Gβ5γ2 is a highly selective activator of phospholipid-dependent enzymes

Journal of Biological Chemistry

Volumn 275, Issue 18, 2000, Pages 13746-13754

  Maier, Udo ^a   Babich, Aleksei ^a   Macrez, Nathalie ^b   Leopoldt, Daniela ^a,d   Gierschik, Peter ^c   Illenberger, Daria ^c   Nürnberg, Bernd ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b CNRS   (France)

^c UNIVERSITY OF ULM   (Germany)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME ACTIVATOR; G PROTEIN COUPLED RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; G PROTEIN BETA GAMMA; G-PROTEIN BETA GAMMA; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; ISOENZYME; PHOSPHOLIPASE C; PHOSPHOLIPASE C BETA; PHOSPHOLIPID; RECOMBINANT PROTEIN;

ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ISOLATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; HUMAN; METABOLISM;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ENZYME ACTIVATION; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; GTP-BINDING PROTEINS; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; ISOENZYMES; PHOSPHOLIPASE C; PHOSPHOLIPIDS; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

EID: 0034607469     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.18.13746     Document Type: Article

References (66)

1. Bockaert, J., and Pin, J. P. (1999) EMBO J. 18, 1723-1729
2. Ji, T. H., Grossmann, M., and Ji, I. (1998) J. Biol. Chem. 273, 17299-17302
3. Wess, J. (1998) Pharmacol. Ther. 80, 231-264
4. Gether, U., and Kobilka, B. K. (1998) J. Biol. Chem. 273, 17979-17982
5. Hamm, H. E. (1998) J. Biol. Chem. 273, 669-672
6. Clapham, D. E., and Neer, E. J. (1997) Annu. Rev. Pharmacol. Toxicol. 37, 167-203
7. Berman, D. M., and Gilman, A. G. (1998) J. Biol. Chem. 273, 1269-1272
8. Kalkbrenner, F., Dippel, E., Wittig, B., and Schultz, G. (1996) Biochim. Biophys. Acta 1314, 125-139
9. Neubig, R. R. (1994) FASEB J. 8, 939-946
10. Degtiar, V., Harhammer, R., and Nürnberg, B. (1997) J. Physiol. (Lond.) 502, 321-333
11. Ford, C. E., Skiba, N. P., Bae, H., Daaka, Y., Reuveny, E., Shekter, L. R., Rosal, R., Weng, G., Yang, C. S., Iyengar, R., Miller, R. J, Jan, L. Y., Lefkowitz, R. J., and Hamm, H. E. (1998) Science 280, 1271-1274
12. Watson, A. J., Katz, A., and Simon, M. I. (1994) J. Biol. Chem. 269, 22150-22156
13. Snow, B. E., Krumins, A. M., Brothers, G. M., Lee, S. F., Wall, M. A., Chung, S., Mangion, J., Arya, S., Gilman, A. G., and Siderovski, D. P. (1988) Proc. Natl. Acad. Sci. U. S. A. 95, 13307-13312
14. Makino, E. R., Handy, J. W., Li, T., and Arshavsky, V. Y. (1999) Proc. Natl. Acad. Sci., U. S. A. 96, 1947-1952
15. Levay, K., Cabrera, J. L., Satpaev, D. K., and Slepak, V. Z. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 2503-2507
16. Snow, B. E., Betts, L., Mangion, J., Sondek, J., and Siderovski, D. P. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 6489-6494
17. Posner, B. A., Gilman, A. G., and Harris B. A. (1999) J. Biol. Chem. 274, 31087-31093
18. Fletcher, J. E., Lindorfer, M. A., DeFilippo, J. M., Yasuda, H., Guilmard, M., and Garrison, J. C. (1998) J. Biol. Chem. 273, 636-644
19. Lindorfer, M. A., Myung, C.-S., Savino, Y., Yasuda, H., Khazan, R., and Garrison, J. C. (1998) J. Biol. Chem. 273, 34429-34436
20. Zhang, S., Coso, O. A., Collins, R., Gutkind, J. S., and Simonds, W. F. (1996) J. Biol. Chem. 271, 20208-20212
21. Camps, M., Carozzi, A., Schnabel, P., Scheer, A., Parker, P. J., and Gierschik, P. (1992) Nature 360, 684-686
22. Illenberger, D., Schwald, F., Pimmer, D., Binder, W., Maier, G., Dietrich, A., and Gierschik, P. (1998) EMBO J. 17, 6241-6249
23. Leopoldt, D., Hanck, T., Exner, T., Maier, U., Wetzker, R., and Nürnberg, B. (1998) J. Biol. Chem. 273, 7024-7029
24. Maier, U., Babich, A., and Nürnberg, B. (1999) J. Biol. Chem. 274, 29311-29317
25. Sinke, R. J., and Geurts van Kessel, A. G. (1995) Genomics 25, 568-569
26. Gierschik, P., and Camps, M. (1994) Methods Enzymol. 238, 181-195
27. Exner, T., Jensen, O. N., Kleuss, C., Mann, M., and Nürnberg, B. (1999) Proc. Natl. Acad. Sci., U. S. A. 96, 1327-1332
28. Leopoldt, D., Harteneck, C., and Nürnberg, B. (1997) Naunyn-Schmiedeberg's Arch. Pharmacol. 356, 216-224
29. Siffert, W., Rosskopf, D., Siffert, G., Busch, S., Moritz, A., Erbel, R., Sharma, A. M., Ritz, E., Wichmann, H. E., Jakobs, K. H., and Horsthemke, B. (1998) Nat. Genet. 18, 45-48
30. Kozasa, T., and Gilman, A. G. (1995) J. Biol. Chem. 270, 1734-1741
31. Stephens, L., Smrcka, A., Cooke, F. T., Jackson, T. H., Sternweis, P. C., and Hawkins, P. T. (1994) Cell 77, 83-93
32. Viard, P., Exner, T., Maier, U., Mironneau, J., Nürnberg, B., and Macrez, N. (1999) FASEB J. 13, 685-694
33. Brunk, I., Pahner, I., Maier, U., Jenner, B., Veh, R. W., Nürnberg, B., and Ahnert-Hilger, G. (1999) Eur. J. Cell Biol. 78, 311-322
34. Carozzi, A. J., Kriz, R. W., Webster, C., and Parker, P. J. (1992) Eur. J. Biochem. 210, 521-529
35. Laemmli, U. K. (1970) Nature 227, 680-685
36. Lepretre, N., Mironneau, J., and Morel, J. L. (1994) J. Biol. Chem. 269, 29546-29552
37. Hawes, B. E., Luttrell, L. M., van Biesen, T., and Lefkowitz, R. J. (1996) J. Biol. Chem. 271, 12133-12136
38. Lopez-Ilasaca, M., Crespo, P., Pellici, P. G., Gutkind, J. S., and Wetzker, R. (1997) Science 275, 394-397
39. Lopez-Ilasaca, M., Gutkind, J. S., and Wetzker, R. (1998) J. Biol. Chem. 273, 2505-2508
40. Boyer, J. L., Graber, S. G., Waldo, G. L., Harden, T. K., and Garrison, J. C. (1994) J. Biol. Chem. 269, 2814-2819
41. Myung, C.-S., Yasuda, H., Liu, W. W., Harden, T. K., and Garrison, J. C. (1999) J. Biol. Chem. 274, 16595-16603
42. Schmidt, C. J., Thomas, T. C., Levine, M. A., and Neer, E. J. (1992) J. Biol. Chem. 267, 13807-13810
43. Pronin, A. N., and Gautam, N. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 6220-6224
44. Quitterer, U., and Lohse, M. J. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 10626-10631
45. Hawes, B. E., van Biesen, T., Koch, W. J., Luttrell, L. M., and Lefkowitz, R. J. (1995) J. Biol. Chem. 270, 17148-17153
46. Garcia, D. E., Li, B., Garcia-Ferreiro, R. E., Hernandez-Ochoa, E. O., Yan, K., Gautam, N., Catterall, W. A., Mackie, K., and Hille, B. (1998) J. Neurosci. 18, 9163-9170
47. Daaka, Y., Pitcher, J. A., Richardson, M., Stoffel, R. H., Robishaw, J. D., and Lefkowitz, R. J. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 2180-2185
48. Bondeva, T., Pirola, L., Bulgarelli-Leva, G., Rubio, I., Wetzker, R., and Wymann, M. P. (1998) Science 282, 293-296
49. Kurosu, H., Maehama, T., Okada, T., Yamamoto, T., Hoshino, S., Fukui, Y., Ui, M., Hazeki, O., and Katada, T. (1997) J. Biol. Chem. 272, 24252-24262
50. Macrez-Lepretre, N., Kalkbrenner, F., Morel, J.-L., Schultz, G., and Mironneau, J. (1997) J. Biol. Chem. 272, 10095-10102
51. Watson, A. J., Aragay, A. M., Slepak, V. Z., and Simon, M. I. (1996) J. Biol. Chem. 271, 28154-28160
52. Park, D., Jhon, D. Y., Lee, C. W., Lee, K. H., and Rhee, S. G. (1993) J. Biol. Chem. 268, 4573-4576
53. Smrcka, A. V., and Sternweis, P. C. (1993) J. Biol. Chem. 268, 9667-9674
54. Hepler, J. R., Kozasa, T., Smrcka, A. V., Simon, M. I., Rhee, S. G., Sternweis, P. C., and Gilman, A. G. (1993) J. Biol. Chem. 268, 14367-14375
55. Exton, J. H. (1997) Eur. J. Biochem. 243, 10-20
56. Jiang, H., Kuang, Y., Wu, Y., Smrcka, A., Simon, M. I., and Wu, D. (1996) J. Biol. Chem. 271, 13430-13434
57. Bayewitch, M. L., Avidor-Reiss, T., Levy, R., Pfeuffer, T., Nevo, I., Simonds, W. F., and Vogel, Z. (1998) J. Biol. Chem. 273, 2273-2276
58. Bayewitch, M. L., Avidor-Reiss, T., Levy, R., Pfeuffer, T., Nevo, I., Simonds, W. F., and Vogel, Z. (1998) FASEB J. 12, 1019-1025
59. Rhee, S. G., and Bae, Y. S. (1997) J. Biol. Chem. 272, 15045-15048
60. Zhang, S., Coso, O. A., Lee, C., Gutkind, J. S., and Simonds, W. F. (1996) J. Biol. Chem. 271, 33575-33579
61. Yan, K., and Gautam, N. (1997) J. Biol. Chem. 272, 2056-2059
62. Li, Y., Sternweis, P. M., Charnecki, S., Smith, T. F., Gilman, A. G., Neer, E. J., and Kozasa, T. (1998) J. Biol. Chem. 273, 16265-16272
63. Panchenko, M. P., Saxena, K., Li, Y., Charnecki, S., Sternweis, P. M., Smith, T. F., Gilman, A. G., Kozasa, T., and Neer, E. J. (1998) J. Biol. Chem. 273, 28298-28304
64. Sankaran, B., Osterhout, J., Wu, D., and Smrcka, A. V. (1998) J. Biol. Chem. 273, 7148-7154
65. Wang, T., Pentyala, S., Rebecchi, M. J., and Scarlata, S. (1999) Biochemistry 38, 1517-1524
66. Buck, E., Li, J., Chen, Y., Weng, G., Scarlata, S., and Iyengar, R. (1999) Science 283, 1332-1335