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••], are the first to identify one of the components of the Hedgehog signaling pathway, costal 2, as a novel kinesin-related protein. In addition, these papers show that costal 2 is in a complex with the transcription factor CI and the protein kinase, fused. This is the first report of a MT motor-like protein in association with a transcription factor and suggests that sequestering and release of the complex from the MT may regulate availability of the transcription factor.
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