Knockout of G protein β5 impairs brain development and causes multiple neurologic abnormalities in mice

Journal of Neurochemistry

Volumn 119, Issue 3, 2011, Pages 544-554

  Zhang, Jian Hua ^a   Pandey, Mritunjay ^a   Seigneur, Erica M ^a   Panicker, Leelamma M ^a,d   Koo, Lily ^b   Schwartz, Owen M ^b   Chen, Weiping ^a   Chen, Ching Kang ^c   Simonds, William F ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

dendrite; dentate gyrus; limbic cortex; Purkinje cell; R7BP; regulator of G protein signaling

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN BETA5 SUBUNIT; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPROTEIN; R7 PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN TISSUE; CEREBELLUM; CONTROLLED STUDY; COORDINATION; DENDRITE; GENE EXPRESSION; GENE INACTIVATION; HIPPOCAMPUS; KNOCKOUT MOUSE; LEARNING; MOTOR ACTIVITY; MOUSE; NERVE CELL DIFFERENTIATION; NERVOUS TISSUE; NEUROLOGIC DISEASE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; SYNAPSE; WALKING;

ABNORMALITIES, MULTIPLE; ANIMALS; BRAIN; CEREBELLUM; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GTP-BINDING PROTEIN BETA SUBUNITS; HIPPOCAMPUS; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; PHENOTYPE;

MUS;

EID: 80054089606     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07457.x     Document Type: Article

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