Synergistic roles for G-protein γ 3and γ 7 subtypes in seizure susceptibility as revealed in double knock-out mice

Journal of Biological Chemistry

Volumn 287, Issue 10, 2012, Pages 7121-7133

  Schwindinger, William F ^a   Mirshahi, Uyenlinh L ^a   Baylor, Kelly A ^a   Sheridan, Kathleen M ^a   Stauffer, Anna M ^a   Usefof, Stephanie ^a   Stecker, Mark M ^a,b   Mirshahi, Tooraj ^a   Robishaw, Janet D ^a  

^a WEIS CENTER FOR RESEARCH   (United States)

^b MARSHALL UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOBUTYRIC ACIDS; BIOCHEMICAL ANALYSIS; BRAIN FUNCTIONS; G PROTEIN; GENE TARGETING; KNOCK OUTS; LIFE SPAN; MOUSE MODELS; PREMATURE DEATH; SEIZURE DISORDERS; SIGNALING PATHWAYS;

AMINO ACIDS; GENETIC ENGINEERING; PIGMENTS; PROTEINS; SIGNALING;

MAMMALS;

4 AMINOBUTYRIC ACID B RECEPTOR; ADENOSINE A2A RECEPTOR; BACLOFEN; DOPAMINE 1 RECEPTOR; G PROTEIN GAMMA3 SUBUNIT; G PROTEIN GAMMA7 SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT; MESSENGER RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CAUSE OF DEATH; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORPUS STRIATUM; DISEASE COURSE; DISEASE SEVERITY; DRUG EFFECT; DRUG EFFICACY; G PROTEIN GAMMA3 SUBUNIT GENE; G PROTEIN GAMMA7 SUBUNIT GENE; GENE; GENE EXPRESSION REGULATION; GENE TARGETING; GENETIC VARIABILITY; KNOCKOUT MOUSE; LIFESPAN; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR PATHOLOGY; MOUSE; NERVE CELL EXCITABILITY; NEUROMODULATION; NEUROPROTECTION; NONHUMAN; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RECEPTOR UPREGULATION; SEIZURE SUSCEPTIBILITY; SIGNAL TRANSDUCTION; SURVIVAL RATE; TONIC CLONIC SEIZURE; TREATMENT DURATION;

ANIMALS; BRAIN; EPILEPSY; GENETIC PREDISPOSITION TO DISEASE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEIN GAMMA SUBUNITS; MICE; MICE, KNOCKOUT; RECEPTOR, ADENOSINE A2A; RECEPTORS, DOPAMINE; RECEPTORS, GABA-B; SIGNAL TRANSDUCTION;

MUS;

EID: 84857736477     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.308395     Document Type: Article

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