The repertoire of heterotrimeric G proteins and RGS proteins in Ciona intestinalis

PLoS ONE

Volumn 4, Issue 10, 2009, Pages

  Prasobh, R ^a   Manoj, Narayanan ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY MADRAS   (India)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; RGS PROTEIN; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN;

ARTICLE; CIONA INTESTINALIS; COMPUTER MODEL; CONTROLLED STUDY; GENETIC CONSERVATION; NONHUMAN; NUCLEOTIDE SEQUENCE; ORTHOLOGY; PROTEIN ANALYSIS; PROTEIN FAMILY; PROTEIN QUATERNARY STRUCTURE; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; UNINDEXED SEQUENCE; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; EXPRESSED SEQUENCE TAG; GENOME; HUMAN; METABOLISM; MOLECULAR GENETICS; PHYLOGENY; PROTEIN TERTIARY STRUCTURE;

CHORDATA; CIONA INTESTINALIS; EUKARYOTA;

AMINO ACID SEQUENCE; ANIMALS; CIONA INTESTINALIS; EXPRESSED SEQUENCE TAGS; GENOME; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEIN STRUCTURE, TERTIARY; RGS PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION;

EID: 70350150309     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007349     Document Type: Article

References (45)

1. Cabrera-Vera TM, Vanhauwe J, Thomas TO, Medkova M, Preininger A, et al. (2003) Insights into G protein structure, function, and regulation. Endocr Rev 24: 765-781.
2. Lambright DG (2004) Heterotrimeric G protein signaling at atomic resolution. In: Bradshaw RA, Dennis EA, eds. Hand book of Cell Signaling. Boston: MA Academic. pp 575-579.
3. Preininger AM, Hamm HE (2004) G protein signaling: insights from new structures. Sci STKE 218: re3.
4. Birnbaumer L (2007) Expansion of signal transduction by G proteins. The second 15 years or so: from 3 to 16 α subunits plus bc dimmers. Biochim Biophys Acta 1768: 772-793.
5. Johnston AC, Siderovski PD (2007) Receptor-Mediated Activation of Heterotrimeric G-Proteins: Current Structural Insights. Mol Pharmacol 72: 219-230.
6. Burchett SA (2000) Regulators of G protein signaling: a bestiary of modular protein binding domains. J Neurochem 75: 1335-1351.
7. Fredriksson R, Lagerstrom MC, Lundin LG, Schioth HB (2003) The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Mol Pharmacol 63: 1256-1272.
8. Clapham DE, Neer EJ (1997) G protein βγ subunits. Annu Rev Pharmacol Toxicol 37: 167-203.
9. Wettschureck N, Offermanns S (2005) Mammalian G Proteins and Their Cell Type Specific Functions. Physiol Rev 85: 1159-1204.
10. Graf R, Mattera R, Codina J, Evans T, Ho YK, et al. (1992) Studies on the interaction of alpha subunits of GTP-binding proteins with beta gamma dimers. Eur J Biochem 210: 609-619.
11. Corbo CJ, Di Gregorio A, Levine M (2001) The ascidian as a model organism in developmental and evolutionary biology. Cell 106: 535-538.
12. Dehal P, Satou Y, Campbell RK, Chapman J, Degnan B, et al. (2002) The draft genome of Ciona intestinalis: insights into chordate and vertebrate origins. Science 298: 2157-2167.
13. Satoh N, Satou Y, Davidson B, Levine M (2003) Ciona intestinalis: an emerging model for whole-genome analyses. Trends Genet 7: 376-381.
14. Delsuc F, Brinkmann H, Chourrout D, Philippe H (2006) Tunicates and not cephalochordates are the closest living relatives of vertebrates. Nature 439: 965-968.
15. Kamesh N, Aradhyam GK, Manoj N (2008) The repertoire of G protein-coupled receptors in the sea squirt Ciona intestinalis. BMC Evo Biol 8: 129.
16. Ciona intestinalis v2.0 Sequencing Project database. (http://genome.jgi-psf.org/Cioin2/Cioin2.home.html).
17. Ciona intestinalis v1.0 Sequencing Project database. (http://genome.jgi-psf.org/ciona4/ciona4.home.html).
18. Theodoropoulou MC, Bagos PG, Spyropoulos IC, Hamodrakas SJ (2008) gpDB: a database of GPCRs, G-proteins, effectors and their interactions. Bioinformatics 24: 1471-1472.
19. Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, et al. (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 25: 3389-3402.
20. Eddy SR (1998) Profile hidden Markov models. Bioinformatics 14: 755-763.
21. Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG (1997) The ClustalX Windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 24: 4876-4882.
22. Hall TA (1999) BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/N. Nucleic Acids Symp 41: 95-98.
23. Felsenstein J (1989) PHYLIP, Phylogeny Inference Package (Version 3.2). Cladistics 5: 164-166.
24. Gouet P, Courcelle E, Stuart DI, Metoz F (1999) ESPript: analysis of multiple sequence alignments in PostScript. Bioinformatics 15: 305-308.
25. Jansen G, Thijssen KL, Werner P, van der Horst M, Hazendonk E, et al. (1999) The complete family of genes encoding G proteins of Caenorhabditis elegans. Nat Genet 21: 414-419.
26. Coleman DE, Berghuis AM, Lee E, Linder ME, Gilman AG, et al. (1994) Structures of active conformations of Gi alpha1 and the mechanism of GTP hydrolysis. Science 265: 1405-1412.
27. Onrust R, Herzmark P, Chi P, Garcia PD, Lichtarge O, et al. (1997) Receptor and βγ binding sites in the a subunit of the retinal G protein transducin. Science 275: 381-384.
28. Sprang SR (1997) G protein mechanisms: insights from structural analysis. Annu Rev Bioche 66: 639-678.
29. Marin EP, Krishna AG, Sakmar TP (2002) Disruption of the alpha5 helix of transducin impairs Rhodopsin-catalyzed nucleotide exchange. Biochemistry 41: 6988-6994.
30. sα: evidence for intramolecular signal transduction. Mol Pharmacol 53: 981-990.
31. sα in which substitutions decrease Receptor-mediated activation and increase receptor affinity. Mol Pharmacol 57: 1081-1092.
32. Resh MD (1996) Regulation of cellular signalling by fatty acid acylation and prenylation of signal transduction proteins. Cell Signal 8: 403-412.
33. Watson AJ, Aragay AM, Slepak VZ, Simon MI (1996) A novel form of the G protein beta subunit Gbeta5 is specifically expressed in the vertebrate retina. J Biol Chem 271: 28154-28160.
34. Jones MB, Siderovski DP, Hooks SB (2004) The G betagamma dimer as a novel source of selectivity in G-protein signaling: GGL-ing at convention. Mol Interv 4: 200-214.
35. iαlβ1γ2,. Cell 83: 1047-1058.
36. Sondek J, Siderovski DP (2001) Gγ-like (GGL) domains: new frontiers in G-protein Signaling and β-propeller scaffolding. Biochem Pharmacol 61: 1329-1337.
37. Davis TL, Bonacci TM, Sprang SR, Smrcka AV (2005) Structural and molecular characterization of a preferred protein interaction surface on G protein beta gamma subunits. Biochemistry 44: 10593-10604.
38. Higgins JB, Casey PJ (1994) In vitro processing of recombinant G protein gamma subunits. Requirements for assembly of an active beta gamma complex. J Biol Chem 269: 9067-9073.
39. Liang JJ, Cockett M, Khawaja XZ (1998) Immunohistochemical localization of G protein β1, β2, β3, β4, β5, and γ3 subunits in the adult rat brain. J Neurochem 71: 345-355.
40. Yost AE, Mervine MS, Sabo LJ, Hynes RT, Berlot HC (2007) Live cell analysis of G protein β5 complex formation, function and targeting. Mol Pharmacol 72: 812-825.
41. 5 subunits. Proc Natl Acad Sci U S A 95: 13307-13312.
42. Marchler-Bauer A, Anderson JB, Chitsaz F, Derbyshire MK, DeWeese-Scott C, et al. (2009) CDD: specific functional annotation with the Conserved Domain Database. Nucleic Acids Res 37(Database issue): D205-10.
43. Chen S, Hamm HE (2006) DEP domains: More than just membrane anchors. Dev Cell 11: 436-438.
44. Cheever ML, Snyder JT, Gershburg S, Siderovski DP, Harden TK, et al. (2008) Crystal structure of the multifunctional Gbeta5-RGS9 complex. Nat Struct Mol Biol 15: 155-162.
45. Imai KS, Levine M, Satoh N, Satou Y (2006) Regulatory blueprint for a chordate embryo. Science 5777: 1183-1187.