Autoinflammatory syndromes and cellular responses to stress: Pathophysiology, diagnosis and new treatment perspectives

Best Practice and Research: Clinical Rheumatology

Volumn 26, Issue 4, 2012, Pages 505-533

  Savic, Sinisa ^a   Dickie, Laura J ^a   Wittmann, Miriam ^a,b,c   McDermott, Michael F ^a  

^a ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

^b UNIVERSITY OF BRADFORD   (United Kingdom)

^c BRADFORD TEACHING HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Autoinflammation; Biological therapy; FMF (familial Mediterranean fever); IL 1 TNF; Metabolism; NLRP3 (Nod like receptor family, pyrin domain containing protein 3) inflammasome; ROS (reactive oxygen species); TRAPS (TNF receptor associated periodic fever syndrome)

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; AMYLIN; C REACTIVE PROTEIN; CASPASE RECRUITMENT DOMAIN PROTEIN 15; COLCHICINE; CRYOPYRIN; DEFICIENCY IN THIRTY SIX RECEPTOR ANTAGONIST; ETANERCEPT; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN RECEPTOR; METHOTREXATE; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 22; NONSTEROID ANTIINFLAMMATORY AGENT; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN PROTEIN; PROTEASOME; RANTES; REACTIVE OXYGEN METABOLITE; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; STAT1 PROTEIN; TOCILIZUMAB; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR RECEPTOR 1; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ADAPTIVE IMMUNITY; ANKYLOSING SPONDYLITIS; ANTIGEN PRESENTING CELL; AUTOIMMUNITY; AUTOINFLAMMATORY DISEASE; CELLULAR STRESS RESPONSE; CHRONIC ATYPICAL NEUTROPHILIC DERMATOSIS WITH LIPODYSTROPHY AND ELEVATED TEMPERATURE; CHRONIC GRANULOMATOUS DISEASE; CINCA SYNDROME; CYTOKINE RELEASE; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; FAMILIAL COLD AUTOINFLAMMATORY SYNDROME; FAMILIAL MEDITERRANEAN FEVER; GENE; GENE DOSAGE; GENE MUTATION; GENETIC ASSOCIATION; GENETIC SCREENING; GRANULOMATOSIS; HUMAN; HYPERIMMUNOGLOBULINEMIA D AND PERIODIC FEVER SYNDROME; IMMUNOPATHOGENESIS; INNATE IMMUNITY; IRON DEFICIENCY ANEMIA; LIPODYSTROPHY; MAJOR HISTOCOMPATIBILITY COMPLEX; MEVALONIC ACIDURIA; MONOGENIC DISORDER; MUCKLE WELLS SYNDROME; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATIVE STRESS; PAPA SYNDROME; PATHOPHYSIOLOGY; PFAPA SYNDROME; PREVALENCE; PRIORITY JOURNAL; PSORIASIS SUSCEPTIBILITY LOCUS 2 GENE; PSORIATIC ARTHRITIS; RETINA MACULA AGE RELATED DEGENERATION; REVIEW; SCHNITZLER SYNDROME; T LYMPHOCYTE SUBPOPULATION; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED PERIODIC SYNDROME; UNFOLDED PROTEIN RESPONSE; WILD TYPE;

CARRIER PROTEINS; CYTOKINES; FAMILIAL MEDITERRANEAN FEVER; HEREDITARY AUTOINFLAMMATORY DISEASES; HUMANS; IMMUNITY, INNATE; INFLAMMASOMES; MUTATION; SYNDROME;

EID: 84867364866     PISSN: 15216942     EISSN: 15321770     Source Type: Journal    
DOI: 10.1016/j.berh.2012.07.009     Document Type: Review

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