-
1
-
-
10744222574
-
WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27
-
Pflanz S, Hibbert L, Mattson J, Rosales R, Vaisberg E, et al. (2004) WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27. J Immunol 172: 2225-2231.
-
(2004)
J Immunol
, vol.172
, pp. 2225-2231
-
-
Pflanz, S.1
Hibbert, L.2
Mattson, J.3
Rosales, R.4
Vaisberg, E.5
-
2
-
-
0038326688
-
Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment
-
Takeda A, Hamano S, Yamanaka A, Hanada T, Ishibashi T, et al. (2003) Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment. J Immunol 170: 4886-4890.
-
(2003)
J Immunol
, vol.170
, pp. 4886-4890
-
-
Takeda, A.1
Hamano, S.2
Yamanaka, A.3
Hanada, T.4
Ishibashi, T.5
-
3
-
-
18444385868
-
IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells
-
Pflanz S, Timans JC, Cheung J, Rosales R, Kanzler H, et al. (2002) IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells. Immunity 16: 779-790.
-
(2002)
Immunity
, vol.16
, pp. 779-790
-
-
Pflanz, S.1
Timans, J.C.2
Cheung, J.3
Rosales, R.4
Kanzler, H.5
-
4
-
-
0344304399
-
IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanisms
-
Lucas S, Ghilardi N, Li J, de Sauvage FJ, (2003) IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and-independent mechanisms. Proc Natl Acad Sci U S A 100: 15047-15052.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 15047-15052
-
-
Lucas, S.1
Ghilardi, N.2
Li, J.3
de Sauvage, F.J.4
-
5
-
-
0141519112
-
IL-27 and IFN-alpha signal via Stat1 and Stat3 and induce T-Bet and IL-12Rbeta2 in naive T cells
-
Hibbert L, Pflanz S, De Waal Malefyt R, Kastelein RA, (2003) IL-27 and IFN-alpha signal via Stat1 and Stat3 and induce T-Bet and IL-12Rbeta2 in naive T cells. J Interferon Cytokine Res 23: 513-522.
-
(2003)
J Interferon Cytokine Res
, vol.23
, pp. 513-522
-
-
Hibbert, L.1
Pflanz, S.2
de Waal Malefyt, R.3
Kastelein, R.A.4
-
6
-
-
84889886017
-
Zeitvogel J, Werfel T, Wittmann M (submitted) IL-27 acts as a Priming Signal for IL-23 but not IL-12 production on human antigen presenting cells
-
Zeitvogel J, Werfel T, Wittmann M (submitted) IL-27 acts as a Priming Signal for IL-23 but not IL-12 production on human antigen presenting cells. submitted.
-
Submitted
-
-
-
7
-
-
67649233028
-
IL-27 is expressed in chronic human eczematous skin lesions and stimulates human keratinocytes
-
Wittmann M, Zeitvogel J, Wang D, Werfel T, (2009) IL-27 is expressed in chronic human eczematous skin lesions and stimulates human keratinocytes. J Allergy Clin Immunol 124: 81-89.
-
(2009)
J Allergy Clin Immunol
, vol.124
, pp. 81-89
-
-
Wittmann, M.1
Zeitvogel, J.2
Wang, D.3
Werfel, T.4
-
8
-
-
77949516634
-
Possible roles of IL-27 in the pathogenesis of psoriasis
-
Shibata S, Tada Y, Kanda N, Nashiro K, Kamata M, et al. (2010) Possible roles of IL-27 in the pathogenesis of psoriasis. J Invest Dermatol 130: 1034-1039.
-
(2010)
J Invest Dermatol
, vol.130
, pp. 1034-1039
-
-
Shibata, S.1
Tada, Y.2
Kanda, N.3
Nashiro, K.4
Kamata, M.5
-
9
-
-
33747593830
-
Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system
-
Stumhofer JS, Laurence A, Wilson EH, Huang E, Tato CM, et al. (2006) Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system. Nat Immunol 7: 937-945.
-
(2006)
Nat Immunol
, vol.7
, pp. 937-945
-
-
Stumhofer, J.S.1
Laurence, A.2
Wilson, E.H.3
Huang, E.4
Tato, C.M.5
-
10
-
-
33749515631
-
Two-sided roles of IL-27: induction of Th1 differentiation on naive CD4+ T cells versus suppression of proinflammatory cytokine production including IL-23-induced IL-17 on activated CD4+ T cells partially through STAT3-dependent mechanism
-
Yoshimura T, Takeda A, Hamano S, Miyazaki Y, Kinjyo I, et al. (2006) Two-sided roles of IL-27: induction of Th1 differentiation on naive CD4+ T cells versus suppression of proinflammatory cytokine production including IL-23-induced IL-17 on activated CD4+ T cells partially through STAT3-dependent mechanism. J Immunol 177: 5377-5385.
-
(2006)
J Immunol
, vol.177
, pp. 5377-5385
-
-
Yoshimura, T.1
Takeda, A.2
Hamano, S.3
Miyazaki, Y.4
Kinjyo, I.5
-
11
-
-
33747588291
-
Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells
-
Batten M, Li J, Yi S, Kljavin NM, Danilenko DM, et al. (2006) Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells. Nat Immunol 7: 929-936.
-
(2006)
Nat Immunol
, vol.7
, pp. 929-936
-
-
Batten, M.1
Li, J.2
Yi, S.3
Kljavin, N.M.4
Danilenko, D.M.5
-
12
-
-
53149133918
-
Amelioration of human lupus-like phenotypes in MRL/lpr mice by overexpression of interleukin 27 receptor alpha (WSX-1)
-
Sugiyama N, Nakashima H, Yoshimura T, Sadanaga A, Shimizu S, et al. (2008) Amelioration of human lupus-like phenotypes in MRL/lpr mice by overexpression of interleukin 27 receptor alpha (WSX-1). Ann Rheum Dis 67: 1461-1467.
-
(2008)
Ann Rheum Dis
, vol.67
, pp. 1461-1467
-
-
Sugiyama, N.1
Nakashima, H.2
Yoshimura, T.3
Sadanaga, A.4
Shimizu, S.5
-
13
-
-
44449140104
-
IL-27 activates human monocytes via STAT1 and suppresses IL-10 production but the inflammatory functions of IL-27 are abrogated by TLRs and p38
-
Kalliolias GD, Ivashkiv LB, (2008) IL-27 activates human monocytes via STAT1 and suppresses IL-10 production but the inflammatory functions of IL-27 are abrogated by TLRs and p38. J Immunol 180: 6325-6333.
-
(2008)
J Immunol
, vol.180
, pp. 6325-6333
-
-
Kalliolias, G.D.1
Ivashkiv, L.B.2
-
14
-
-
47249089097
-
IL-1, IL-18, and IL-33 families of cytokines
-
Arend WP, Palmer G, Gabay C, (2008) IL-1, IL-18, and IL-33 families of cytokines. Immunol Rev 223: 20-38.
-
(2008)
Immunol Rev
, vol.223
, pp. 20-38
-
-
Arend, W.P.1
Palmer, G.2
Gabay, C.3
-
15
-
-
13444254086
-
Interleukin-18: a therapeutic target in rheumatoid arthritis?
-
McInnes IB, Liew FY, Gracie JA, (2005) Interleukin-18: a therapeutic target in rheumatoid arthritis? Arthritis Res Ther 7: 38-41.
-
(2005)
Arthritis Res Ther
, vol.7
, pp. 38-41
-
-
McInnes, I.B.1
Liew, F.Y.2
Gracie, J.A.3
-
16
-
-
4644308152
-
Interleukin-18 bioactivity: a novel target for immunopharmacological anti-inflammatory intervention
-
Muhl H, Pfeilschifter J, (2004) Interleukin-18 bioactivity: a novel target for immunopharmacological anti-inflammatory intervention. Eur J Pharmacol 500: 63-71.
-
(2004)
Eur J Pharmacol
, vol.500
, pp. 63-71
-
-
Muhl, H.1
Pfeilschifter, J.2
-
18
-
-
0033952638
-
The role of IL-18 in innate immunity
-
Akira S, (2000) The role of IL-18 in innate immunity. Curr Opin Immunol 12: 59-63.
-
(2000)
Curr Opin Immunol
, vol.12
, pp. 59-63
-
-
Akira, S.1
-
19
-
-
18844481515
-
Defective NK cell activity and Th1 response in IL-18-deficient mice
-
Takeda K, Tsutsui H, Yoshimoto T, Adachi O, Yoshida N, et al. (1998) Defective NK cell activity and Th1 response in IL-18-deficient mice. Immunity 8: 383-390.
-
(1998)
Immunity
, vol.8
, pp. 383-390
-
-
Takeda, K.1
Tsutsui, H.2
Yoshimoto, T.3
Adachi, O.4
Yoshida, N.5
-
20
-
-
55449129909
-
Interleukin-18-deficient mice exhibit diminished chronic inflammation and airway remodelling in ovalbumin-induced asthma model
-
Yamagata S, Tomita K, Sato R, Niwa A, Higashino H, et al. (2008) Interleukin-18-deficient mice exhibit diminished chronic inflammation and airway remodelling in ovalbumin-induced asthma model. Clin Exp Immunol 154: 295-304.
-
(2008)
Clin Exp Immunol
, vol.154
, pp. 295-304
-
-
Yamagata, S.1
Tomita, K.2
Sato, R.3
Niwa, A.4
Higashino, H.5
-
21
-
-
20544448597
-
Human keratinocytes respond to interleukin-18: implication for the course of chronic inflammatory skin diseases
-
Wittmann M, Purwar R, Hartmann C, Gutzmer R, Werfel T, (2005) Human keratinocytes respond to interleukin-18: implication for the course of chronic inflammatory skin diseases. J Invest Dermatol 124: 1225-1233.
-
(2005)
J Invest Dermatol
, vol.124
, pp. 1225-1233
-
-
Wittmann, M.1
Purwar, R.2
Hartmann, C.3
Gutzmer, R.4
Werfel, T.5
-
22
-
-
0037259311
-
Serum levels of interleukin-18 and s-ICAM-1 in patients affected by psoriasis: preliminary considerations
-
Gangemi S, Merendino RA, Guarneri F, Minciullo PL, DiLorenzo G, et al. (2003) Serum levels of interleukin-18 and s-ICAM-1 in patients affected by psoriasis: preliminary considerations. J Eur Acad Dermatol Venereol 17: 42-46.
-
(2003)
J Eur Acad Dermatol Venereol
, vol.17
, pp. 42-46
-
-
Gangemi, S.1
Merendino, R.A.2
Guarneri, F.3
Minciullo, P.L.4
DiLorenzo, G.5
-
23
-
-
54949137275
-
Evidence for a pathogenetic role of interleukin-18 in cutaneous lupus erythematosus
-
Wang D, Drenker M, Eiz-Vesper B, Werfel T, Wittmann M, (2008) Evidence for a pathogenetic role of interleukin-18 in cutaneous lupus erythematosus. Arthritis Rheum 58: 3205-3215.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 3205-3215
-
-
Wang, D.1
Drenker, M.2
Eiz-Vesper, B.3
Werfel, T.4
Wittmann, M.5
-
24
-
-
6344259982
-
Elevated interleukin-18 protein expression in early active and progressive plaque-type psoriatic lesions
-
Companjen A, van der Wel L, van der Fits L, Laman J, Prens E, (2004) Elevated interleukin-18 protein expression in early active and progressive plaque-type psoriatic lesions. Eur Cytokine Netw 15: 210-216.
-
(2004)
Eur Cytokine Netw
, vol.15
, pp. 210-216
-
-
Companjen, A.1
van der Wel, L.2
van der Fits, L.3
Laman, J.4
Prens, E.5
-
25
-
-
36249006497
-
The activity of caspase-1 is increased in lesional psoriatic epidermis
-
Johansen C, Moeller K, Kragballe K, Iversen L, (2007) The activity of caspase-1 is increased in lesional psoriatic epidermis. J Invest Dermatol 127: 2857-2864.
-
(2007)
J Invest Dermatol
, vol.127
, pp. 2857-2864
-
-
Johansen, C.1
Moeller, K.2
Kragballe, K.3
Iversen, L.4
-
27
-
-
0032709099
-
Human keratinocytes constitutively express interleukin-18 and secrete biologically active interleukin-18 after treatment with pro-inflammatory mediators and dinitrochlorobenzene
-
Naik SM, Cannon G, Burbach GJ, Singh SR, Swerlick RA, et al. (1999) Human keratinocytes constitutively express interleukin-18 and secrete biologically active interleukin-18 after treatment with pro-inflammatory mediators and dinitrochlorobenzene. J Invest Dermatol 113: 766-772.
-
(1999)
J Invest Dermatol
, vol.113
, pp. 766-772
-
-
Naik, S.M.1
Cannon, G.2
Burbach, G.J.3
Singh, S.R.4
Swerlick, R.A.5
-
28
-
-
0034130905
-
Expression of IL-18 in human keratinocytes
-
Companjen AR, Prens E, Mee JB, Groves RW, (2000) Expression of IL-18 in human keratinocytes. J Invest Dermatol 114: 598-599.
-
(2000)
J Invest Dermatol
, vol.114
, pp. 598-599
-
-
Companjen, A.R.1
Prens, E.2
Mee, J.B.3
Groves, R.W.4
-
29
-
-
0347627721
-
Human dendritic cells express the IL-18R and are chemoattracted to IL-18
-
Gutzmer R, Langer K, Mommert S, Wittmann M, Kapp A, et al. (2003) Human dendritic cells express the IL-18R and are chemoattracted to IL-18. J Immunol 171: 6363-6371.
-
(2003)
J Immunol
, vol.171
, pp. 6363-6371
-
-
Gutzmer, R.1
Langer, K.2
Mommert, S.3
Wittmann, M.4
Kapp, A.5
-
30
-
-
0034523052
-
Regulation of interleukin-18 (IL-18) expression in keratinocytes (HaCaT): implications for early wound healing
-
Kampfer H, Muhl H, Manderscheid M, Kalina U, Kauschat D, et al. (2000) Regulation of interleukin-18 (IL-18) expression in keratinocytes (HaCaT): implications for early wound healing. Eur Cytokine Netw 11: 626-633.
-
(2000)
Eur Cytokine Netw
, vol.11
, pp. 626-633
-
-
Kampfer, H.1
Muhl, H.2
Manderscheid, M.3
Kalina, U.4
Kauschat, D.5
-
31
-
-
2942530949
-
Identification of residues in an orthopoxvirus interleukin-18 binding protein involved in ligand binding and species specificity
-
Esteban DJ, Buller RM, (2004) Identification of residues in an orthopoxvirus interleukin-18 binding protein involved in ligand binding and species specificity. Virology 323: 197-207.
-
(2004)
Virology
, vol.323
, pp. 197-207
-
-
Esteban, D.J.1
Buller, R.M.2
-
32
-
-
0141570561
-
Vaccinia virus interleukin-18-binding protein promotes virulence by reducing gamma interferon production and natural killer and T-cell activity
-
Reading PC, Smith GL, (2003) Vaccinia virus interleukin-18-binding protein promotes virulence by reducing gamma interferon production and natural killer and T-cell activity. J Virol 77: 9960-9968.
-
(2003)
J Virol
, vol.77
, pp. 9960-9968
-
-
Reading, P.C.1
Smith, G.L.2
-
33
-
-
0033613224
-
IL-18 binding and inhibition of interferon gamma induction by human poxvirus-encoded proteins
-
Xiang Y, Moss B, (1999) IL-18 binding and inhibition of interferon gamma induction by human poxvirus-encoded proteins. Proc Natl Acad Sci U S A 96: 11537-11542.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 11537-11542
-
-
Xiang, Y.1
Moss, B.2
-
34
-
-
0037320267
-
Molluscum contagiosum virus interleukin-18 (IL-18) binding protein is secreted as a full-length form that binds cell surface glycosaminoglycans through the C-terminal tail and a furin-cleaved form with only the IL-18 binding domain
-
Xiang Y, Moss B, (2003) Molluscum contagiosum virus interleukin-18 (IL-18) binding protein is secreted as a full-length form that binds cell surface glycosaminoglycans through the C-terminal tail and a furin-cleaved form with only the IL-18 binding domain. J Virol 77: 2623-2630.
-
(2003)
J Virol
, vol.77
, pp. 2623-2630
-
-
Xiang, Y.1
Moss, B.2
-
35
-
-
0035399616
-
Both E6 and E7 oncoproteins of human papillomavirus 16 inhibit IL-18-induced IFN-gamma production in human peripheral blood mononuclear and NK cells
-
Lee SJ, Cho YS, Cho MC, Shim JH, Lee KA, et al. (2001) Both E6 and E7 oncoproteins of human papillomavirus 16 inhibit IL-18-induced IFN-gamma production in human peripheral blood mononuclear and NK cells. J Immunol 167: 497-504.
-
(2001)
J Immunol
, vol.167
, pp. 497-504
-
-
Lee, S.J.1
Cho, Y.S.2
Cho, M.C.3
Shim, J.H.4
Lee, K.A.5
-
36
-
-
68949207806
-
IL-18 neutralization ameliorates obstruction-induced epithelial-mesenchymal transition and renal fibrosis
-
Bani-Hani AH, Leslie JA, Asanuma H, Dinarello CA, Campbell MT, et al. (2009) IL-18 neutralization ameliorates obstruction-induced epithelial-mesenchymal transition and renal fibrosis. Kidney Int 76: 500-511.
-
(2009)
Kidney Int
, vol.76
, pp. 500-511
-
-
Bani-Hani, A.H.1
Leslie, J.A.2
Asanuma, H.3
Dinarello, C.A.4
Campbell, M.T.5
-
37
-
-
35548946223
-
T helper 1 cells stimulated with ovalbumin and IL-18 induce airway hyperresponsiveness and lung fibrosis by IFN-gamma and IL-13 production
-
Hayashi N, Yoshimoto T, Izuhara K, Matsui K, Tanaka T, et al. (2007) T helper 1 cells stimulated with ovalbumin and IL-18 induce airway hyperresponsiveness and lung fibrosis by IFN-gamma and IL-13 production. Proc Natl Acad Sci U S A 104: 14765-14770.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 14765-14770
-
-
Hayashi, N.1
Yoshimoto, T.2
Izuhara, K.3
Matsui, K.4
Tanaka, T.5
-
38
-
-
78149244847
-
Overexpression of interleukin-18 aggravates cardiac fibrosis and diastolic dysfunction in fructose-fed rats
-
Xing SS, Bi XP, Tan HW, Zhang Y, Xing QC, et al. (2010) Overexpression of interleukin-18 aggravates cardiac fibrosis and diastolic dysfunction in fructose-fed rats. Mol Med 16: 465-470.
-
(2010)
Mol Med
, vol.16
, pp. 465-470
-
-
Xing, S.S.1
Bi, X.P.2
Tan, H.W.3
Zhang, Y.4
Xing, Q.C.5
-
39
-
-
67650067281
-
IL-18 induction of osteopontin mediates cardiac fibrosis and diastolic dysfunction in mice
-
Yu Q, Vazquez R, Khojeini EV, Patel C, Venkataramani R, et al. (2009) IL-18 induction of osteopontin mediates cardiac fibrosis and diastolic dysfunction in mice. Am J Physiol Heart Circ Physiol 297: H76-85.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
-
-
Yu, Q.1
Vazquez, R.2
Khojeini, E.V.3
Patel, C.4
Venkataramani, R.5
-
40
-
-
33947726182
-
IL-18 enhances IFN-gamma-induced production of CXCL9, CXCL10, and CXCL11 in human keratinocytes
-
Kanda N, Shimizu T, Tada Y, Watanabe S, (2007) IL-18 enhances IFN-gamma-induced production of CXCL9, CXCL10, and CXCL11 in human keratinocytes. Eur J Immunol 37: 338-350.
-
(2007)
Eur J Immunol
, vol.37
, pp. 338-350
-
-
Kanda, N.1
Shimizu, T.2
Tada, Y.3
Watanabe, S.4
-
41
-
-
0032983336
-
Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response
-
Novick D, Kim SH, Fantuzzi G, Reznikov LL, Dinarello CA, et al. (1999) Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response. Immunity 10: 127-136.
-
(1999)
Immunity
, vol.10
, pp. 127-136
-
-
Novick, D.1
Kim, S.H.2
Fantuzzi, G.3
Reznikov, L.L.4
Dinarello, C.A.5
-
42
-
-
0033974776
-
Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18
-
Kim SH, Eisenstein M, Reznikov L, Fantuzzi G, Novick D, et al. (2000) Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18. Proc Natl Acad Sci U S A 97: 1190-1195.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 1190-1195
-
-
Kim, S.H.1
Eisenstein, M.2
Reznikov, L.3
Fantuzzi, G.4
Novick, D.5
-
43
-
-
0343775741
-
Interferon-gamma mediates gene expression of IL-18 binding protein in nonleukocytic cells
-
Muhl H, Kampfer H, Bosmann M, Frank S, Radeke H, et al. (2000) Interferon-gamma mediates gene expression of IL-18 binding protein in nonleukocytic cells. Biochem Biophys Res Commun 267: 960-963.
-
(2000)
Biochem Biophys Res Commun
, vol.267
, pp. 960-963
-
-
Muhl, H.1
Kampfer, H.2
Bosmann, M.3
Frank, S.4
Radeke, H.5
-
44
-
-
75749116720
-
HIV-1 causes an imbalance in the production of interleukin-18 and its natural antagonist in HIV-infected individuals: implications for enhanced viral replication
-
Iannello A, Boulassel MR, Samarani S, Tremblay C, Toma E, et al. (2010) HIV-1 causes an imbalance in the production of interleukin-18 and its natural antagonist in HIV-infected individuals: implications for enhanced viral replication. J Infect Dis 201: 608-617.
-
(2010)
J Infect Dis
, vol.201
, pp. 608-617
-
-
Iannello, A.1
Boulassel, M.R.2
Samarani, S.3
Tremblay, C.4
Toma, E.5
-
45
-
-
0035892991
-
Expression and release of IL-18 binding protein in response to IFN-gamma
-
Paulukat J, Bosmann M, Nold M, Garkisch S, Kampfer H, et al. (2001) Expression and release of IL-18 binding protein in response to IFN-gamma. J Immunol 167: 7038-7043.
-
(2001)
J Immunol
, vol.167
, pp. 7038-7043
-
-
Paulukat, J.1
Bosmann, M.2
Nold, M.3
Garkisch, S.4
Kampfer, H.5
-
46
-
-
0345268692
-
Interferon-gamma induces expression of interleukin-18 binding protein in fibroblast-like synoviocytes
-
Moller B, Paulukat J, Nold M, Behrens M, Kukoc-Zivojnov N, et al. (2003) Interferon-gamma induces expression of interleukin-18 binding protein in fibroblast-like synoviocytes. Rheumatology (Oxford) 42: 442-445.
-
(2003)
Rheumatology (Oxford)
, vol.42
, pp. 442-445
-
-
Moller, B.1
Paulukat, J.2
Nold, M.3
Behrens, M.4
Kukoc-Zivojnov, N.5
-
47
-
-
0037168677
-
The promoter of IL-18 binding protein: activation by an IFN-gamma -induced complex of IFN regulatory factor 1 and CCAAT/enhancer binding protein beta
-
Hurgin V, Novick D, Rubinstein M, (2002) The promoter of IL-18 binding protein: activation by an IFN-gamma-induced complex of IFN regulatory factor 1 and CCAAT/enhancer binding protein beta. Proc Natl Acad Sci U S A 99: 16957-16962.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 16957-16962
-
-
Hurgin, V.1
Novick, D.2
Rubinstein, M.3
-
48
-
-
69849090731
-
Molecular mechanisms of IL-18BP regulation in DLD-1 cells: pivotal direct action of the STAT1/GAS axis on the promoter level
-
Bachmann M, Paulukat J, Pfeilschifter J, Muhl H, (2009) Molecular mechanisms of IL-18BP regulation in DLD-1 cells: pivotal direct action of the STAT1/GAS axis on the promoter level. J Cell Mol Med 13: 1987-1994.
-
(2009)
J Cell Mol Med
, vol.13
, pp. 1987-1994
-
-
Bachmann, M.1
Paulukat, J.2
Pfeilschifter, J.3
Muhl, H.4
-
49
-
-
84155180926
-
beta2 adrenergic activation induces the expression of IL-18 binding protein, a potent inhibitor of isoproterenol induced cardiomyocyte hypertrophy in vitro and myocardial hypertrophy in vivo
-
Murray DR, Mummidi S, Valente AJ, Yoshida T, Somanna NK, et al. (2011) beta2 adrenergic activation induces the expression of IL-18 binding protein, a potent inhibitor of isoproterenol induced cardiomyocyte hypertrophy in vitro and myocardial hypertrophy in vivo. J Mol Cell Cardiol 52: 206-218.
-
(2011)
J Mol Cell Cardiol
, vol.52
, pp. 206-218
-
-
Murray, D.R.1
Mummidi, S.2
Valente, A.J.3
Yoshida, T.4
Somanna, N.K.5
-
50
-
-
0036379347
-
Interferon-alpha induces interleukin-18 binding protein in chronic hepatitis C patients
-
Kaser A, Novick D, Rubinstein M, Siegmund B, Enrich B, et al. (2002) Interferon-alpha induces interleukin-18 binding protein in chronic hepatitis C patients. Clin Exp Immunol 129: 332-338.
-
(2002)
Clin Exp Immunol
, vol.129
, pp. 332-338
-
-
Kaser, A.1
Novick, D.2
Rubinstein, M.3
Siegmund, B.4
Enrich, B.5
-
51
-
-
67649359509
-
Use of IL-18 production in a human keratinocyte cell line to discriminate contact sensitizers from irritants and low molecular weight respiratory allergens
-
Corsini E, Mitjans M, Galbiati V, Lucchi L, Galli CL, et al. (2009) Use of IL-18 production in a human keratinocyte cell line to discriminate contact sensitizers from irritants and low molecular weight respiratory allergens. Toxicol In Vitro 23: 789-796.
-
(2009)
Toxicol In Vitro
, vol.23
, pp. 789-796
-
-
Corsini, E.1
Mitjans, M.2
Galbiati, V.3
Lucchi, L.4
Galli, C.L.5
-
52
-
-
33847336449
-
Interleukin-18 and the pathogenesis of inflammatory diseases
-
Dinarello CA, (2007) Interleukin-18 and the pathogenesis of inflammatory diseases. Semin Nephrol 27: 98-114.
-
(2007)
Semin Nephrol
, vol.27
, pp. 98-114
-
-
Dinarello, C.A.1
-
53
-
-
4344573548
-
Increased expression of IL-18 in cutaneous graft-versus-host disease
-
Park HJ, Kim JE, Lee JY, Cho BK, Lee WJ, et al. (2004) Increased expression of IL-18 in cutaneous graft-versus-host disease. Immunol Lett 95: 57-61.
-
(2004)
Immunol Lett
, vol.95
, pp. 57-61
-
-
Park, H.J.1
Kim, J.E.2
Lee, J.Y.3
Cho, B.K.4
Lee, W.J.5
-
54
-
-
26244435934
-
Th1 cytokines in the pathogenesis of lupus nephritis: the role of IL-18
-
Calvani N, Tucci M, Richards HB, Tartaglia P, Silvestris F, (2005) Th1 cytokines in the pathogenesis of lupus nephritis: the role of IL-18. Autoimmun Rev 4: 542-548.
-
(2005)
Autoimmun Rev
, vol.4
, pp. 542-548
-
-
Calvani, N.1
Tucci, M.2
Richards, H.B.3
Tartaglia, P.4
Silvestris, F.5
-
56
-
-
77956261780
-
Expressions of IL-18 and its binding protein in peripheral blood leukocytes and kidney tissues of lupus nephritis patients
-
Hu D, Liu X, Chen S, Bao C, (2010) Expressions of IL-18 and its binding protein in peripheral blood leukocytes and kidney tissues of lupus nephritis patients. Clin Rheumatol 29: 717-721.
-
(2010)
Clin Rheumatol
, vol.29
, pp. 717-721
-
-
Hu, D.1
Liu, X.2
Chen, S.3
Bao, C.4
-
57
-
-
75349084506
-
High circulating levels of free interleukin-18 in patients with active SLE in the presence of elevated levels of interleukin-18 binding protein
-
Novick D, Elbirt D, Miller G, Dinarello CA, Rubinstein M, et al. (2010) High circulating levels of free interleukin-18 in patients with active SLE in the presence of elevated levels of interleukin-18 binding protein. J Autoimmun 34: 121-126.
-
(2010)
J Autoimmun
, vol.34
, pp. 121-126
-
-
Novick, D.1
Elbirt, D.2
Miller, G.3
Dinarello, C.A.4
Rubinstein, M.5
-
58
-
-
38949124339
-
IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced Langerhans cell migration in murine epidermis
-
Antonopoulos C, Cumberbatch M, Mee JB, Dearman RJ, Wei XQ, et al. (2008) IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced Langerhans cell migration in murine epidermis. J Leukoc Biol 83: 361-367.
-
(2008)
J Leukoc Biol
, vol.83
, pp. 361-367
-
-
Antonopoulos, C.1
Cumberbatch, M.2
Mee, J.B.3
Dearman, R.J.4
Wei, X.Q.5
-
59
-
-
69949149477
-
IL-18 activity in systemic lupus erythematosus
-
Favilli F, Anzilotti C, Martinelli L, Quattroni P, De Martino S, et al. (2009) IL-18 activity in systemic lupus erythematosus. Ann N Y Acad Sci 1173: 301-309.
-
(2009)
Ann N Y Acad Sci
, vol.1173
, pp. 301-309
-
-
Favilli, F.1
Anzilotti, C.2
Martinelli, L.3
Quattroni, P.4
de Martino, S.5
-
60
-
-
0036845058
-
Plasma levels of interleukin-18 and interleukin-18 binding protein are elevated in patients with chronic liver disease
-
Ludwiczek O, Kaser A, Novick D, Dinarello CA, Rubinstein M, et al. (2002) Plasma levels of interleukin-18 and interleukin-18 binding protein are elevated in patients with chronic liver disease. J Clin Immunol 22: 331-337.
-
(2002)
J Clin Immunol
, vol.22
, pp. 331-337
-
-
Ludwiczek, O.1
Kaser, A.2
Novick, D.3
Dinarello, C.A.4
Rubinstein, M.5
-
61
-
-
9444247540
-
Evidence for altered interleukin 18 (IL)-18 pathway in human heart failure
-
Mallat Z, Heymes C, Corbaz A, Logeart D, Alouani S, et al. (2004) Evidence for altered interleukin 18 (IL)-18 pathway in human heart failure. FASEB J 18: 1752-1754.
-
(2004)
FASEB J
, vol.18
, pp. 1752-1754
-
-
Mallat, Z.1
Heymes, C.2
Corbaz, A.3
Logeart, D.4
Alouani, S.5
-
62
-
-
34447521412
-
The interleukin-22/STAT3 pathway potentiates expression of inducible nitric-oxide synthase in human colon carcinoma cells
-
Ziesche E, Bachmann M, Kleinert H, Pfeilschifter J, Muhl H, (2007) The interleukin-22/STAT3 pathway potentiates expression of inducible nitric-oxide synthase in human colon carcinoma cells. J Biol Chem 282: 16006-16015.
-
(2007)
J Biol Chem
, vol.282
, pp. 16006-16015
-
-
Ziesche, E.1
Bachmann, M.2
Kleinert, H.3
Pfeilschifter, J.4
Muhl, H.5
-
63
-
-
33746687953
-
Pharmacokinetics of IL-18 binding protein in healthy volunteers and subjects with rheumatoid arthritis or plaque psoriasis
-
Tak PP, Bacchi M, Bertolino M, (2006) Pharmacokinetics of IL-18 binding protein in healthy volunteers and subjects with rheumatoid arthritis or plaque psoriasis. Eur J Drug Metab Pharmacokinet 31: 109-116.
-
(2006)
Eur J Drug Metab Pharmacokinet
, vol.31
, pp. 109-116
-
-
Tak, P.P.1
Bacchi, M.2
Bertolino, M.3
-
64
-
-
83055163376
-
IL-37: a new anti-inflammatory cytokine of the IL-1 family
-
Boraschi D, Lucchesi D, Hainzl S, Leitner M, Maier E, et al. (2011) IL-37: a new anti-inflammatory cytokine of the IL-1 family. Eur Cytokine Netw 22: 127-147.
-
(2011)
Eur Cytokine Netw
, vol.22
, pp. 127-147
-
-
Boraschi, D.1
Lucchesi, D.2
Hainzl, S.3
Leitner, M.4
Maier, E.5
-
65
-
-
77958149102
-
IL-37 is a fundamental inhibitor of innate immunity
-
Nold MF, Nold-Petry CA, Zepp JA, Palmer BE, Bufler P, et al. (2010) IL-37 is a fundamental inhibitor of innate immunity. Nat Immunol 11: 1014-1022.
-
(2010)
Nat Immunol
, vol.11
, pp. 1014-1022
-
-
Nold, M.F.1
Nold-Petry, C.A.2
Zepp, J.A.3
Palmer, B.E.4
Bufler, P.5
-
66
-
-
69849108798
-
Activation of interferon regulatory factor-3 via toll-like receptor 3 and immunomodulatory functions detected in A549 lung epithelial cells exposed to misplaced U1-snRNA
-
Sadik CD, Bachmann M, Pfeilschifter J, Muhl H, (2009) Activation of interferon regulatory factor-3 via toll-like receptor 3 and immunomodulatory functions detected in A549 lung epithelial cells exposed to misplaced U1-snRNA. Nucleic Acids Res 37: 5041-5056.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 5041-5056
-
-
Sadik, C.D.1
Bachmann, M.2
Pfeilschifter, J.3
Muhl, H.4
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