Is caspase 1 central to activation of interleukin-1?

Joint Bone Spine

Volumn 78, Issue 4, 2011, Pages 327-330

  Wittmann, Miriam ^a,b   Kingsbury, Sarah R ^c   McDermott, Michael F ^c  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

Caspase 1; Interleukin 1; Metalloproteases; Neutrophil serine proteases

Indexed keywords

CANAKINUMAB; CASPASE 1 INHIBITOR; CASPASE INHIBITOR; CATHEPSIN G; CRYOPYRIN; GELATINASE B; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MYELOBLASTIN; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RILONACEPT; UNCLASSIFIED DRUG;

ARTHRITIS; BIOLOGICAL ACTIVITY; CINCA SYNDROME; CYTOKINE RELEASE; DRUG EFFICACY; EDITORIAL; ENZYME ACTIVATION; ENZYME INHIBITION; GOUT; HUMAN; IMMUNOPATHOGENESIS; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN FUNCTION; PSEUDOGOUT; RHEUMATOID ARTHRITIS; SCHNITZLER SYNDROME; SJOEGREN SYNDROME;

CASPASE 1; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INFLAMMASOMES; INTERLEUKIN-1BETA; METALLOPROTEASES; SERINE PROTEASES;

EID: 79960634959     PISSN: 1297319X     EISSN: 17787254     Source Type: Journal    
DOI: 10.1016/j.jbspin.2011.02.004     Document Type: Editorial

References (31)

1. Gabay C., Lamacchia C., Palmer G. IL-1 pathways in inflammation and human diseases. Nat Rev Rheumatol 2010, 6:232-241.
2. Molto A., Olive A. Anti-IL-1 molecules: new comers and new indications. Joint Bone Spine 2010, 77:102-107.
3. Cohen I., Rider P., Carmi Y., et al. Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation. Proc Natl Acad Sci U S A 2010, 107:2574-2579.
4. Keller M., Ruegg A., Werner S., et al. Active caspase-1 is a regulator of unconventional protein secretion. Cell 2008, 132:818-831.
5. Netea M.G., Simon A., van de Veerdonk F., et al. IL-1beta processing in host defense: beyond the inflammasomes. PLoS Pathog 2010, 6:e1000661.
6. Joosten L.A., Netea M.G., Fantuzzi G., et al. Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta. Arthritis Rheum 2009, 60:3651-3662.
7. Guma M., Ronacher L., Liu-Bryan R., et al. Caspase 1-independent activation of interleukin-1beta in neutrophil-predominant inflammation. Arthritis Rheum 2009, 60:3642-3650.
8. Stehlik C. Multiple interleukin-1beta-converting enzymes contribute to inflammatory arthritis. Arthritis Rheum 2009, 60:3524-3530.
9. Schonbeck U., Mach F., Libby P. Generation of biologically active IL-1 beta by matrix metalloproteinases: a novel caspase-1-independent pathway of IL-1 beta processing. J Immunol 1998, 161:3340-3346.
10. Coeshott C., Ohnemus C., Pilyavskaya A., et al. Converting enzyme-independent release of tumor necrosis factor alpha and IL-1beta from a stimulated human monocytic cell line in the presence of activated neutrophils or purified proteinase 3. Proc Natl Acad Sci U S A 1999, 96:6261-6266.
11. Meyer-Hoffert U., Wiedow O. Neutrophil serine proteases: mediators of innate immune responses. Curr Opin Hematol 2010, [Epub ahead of print, Oct 29, 2010].
12. Herzog C., Kaushal G.P., Haun R.S. Generation of biologically active interleukin-1beta by meprin B. Cytokine 2005, 31:394-403.
13. Irmler M., Hertig S., MacDonald H.R., et al. Granzyme A is an interleukin 1 beta-converting enzyme. J Exp Med 1995, 181:1917-1922.
14. Omoto Y., Yamanaka K., Tokime K., et al. Granzyme B is a novel interleukin-18 converting enzyme. J Dermatol Sci 2010, 59:129-135.
15. Taxman D.J., Huang M.T., Ting J.P. Inflammasome inhibition as a pathogenic stealth mechanism. Cell Host Microbe 2010, 8:7-11.
16. Dinarello C.A. Anti-inflammatory agents: present and future. Cell 2010, 140:935-950.
17. Black R.A., Kronheim S.R., Merriam J.E., et al. A pre-aspartate-specific protease from human leukocytes that cleaves pro-interleukin-1 beta. J Biol Chem 1989, 264:5323-5326.
18. Kostura M.J., Tocci M.J., Limjuco G., et al. Identification of a monocyte specific pre-interleukin 1 beta convertase activity. Proc Natl Acad Sci U S A 1989, 86:5227-5231.
19. Sugawara S. Immune functions of proteinase 3. Crit Rev Immunol 2005, 25:343-360.
20. Black R.A., Kronheim S.R., Cantrell M., et al. Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor. J Biol Chem 1988, 263:9437-9442.
21. Hazuda D.J., Strickler J., Kueppers F., et al. Processing of precursor interleukin 1 beta and inflammatory disease. J Biol Chem 1990, 265:6318-6322.
22. Robertson S.E., Young J.D., Kitson S., et al. Expression and alternative processing of IL-18 in human neutrophils. Eur J Immunol 2006, 36:722-731.
23. Mizutani H., Schechter N., Lazarus G., et al. Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase. J Exp Med 1991, 174:821-825.
24. Omoto Y., Tokime K., Yamanaka K., et al. Human mast cell chymase cleaves pro-IL-18 and generates a novel and biologically active IL-18 fragment. J Immunol 2006, 177:8315-8319.
25. Nylander-Lundqvist E., Egelrud T. Formation of active IL-1 beta from pro-IL-1 beta catalyzed by stratum corneum chymotryptic enzyme in vitro. Acta Derm Venereol 1997, 77:203-206.
26. Matsushima K., Taguchi M., Kovacs E.J., et al. Intracellular localization of human monocyte associated interleukin 1 (IL 1) activity and release of biologically active IL 1 from monocytes by trypsin and plasmin. J Immunol 1986, 136:2883-2891.
27. Maelfait J., Vercammen E., Janssens S., et al. Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8. J Exp Med 2008, 205:1967-1973.
28. Ito A., Mukaiyama A., Itoh Y., et al. Degradation of interleukin 1beta by matrix metalloproteinases. J Biol Chem 1996, 271:14657-14660.
29. Que X., Kim S.H., Sajid M., et al. A surface amebic cysteine proteinase inactivates interleukin-18. Infect Immun 2003, 71:1274-1280.
30. Zhang Z., Wang L., Seydel K.B., et al. Entamoeba histolytica cysteine proteinases with interleukin-1 beta converting enzyme (ICE) activity cause intestinal inflammation and tissue damage in amoebiasis. Mol Microbiol 2000, 37:542-548.
31. Beausejour A., Grenier D., Goulet J.P., et al. Proteolytic activation of the interleukin-1beta precursor by Candida albicans. Infect Immun 1998, 66:676-681.