Abnormal disulfide-linked oligomerization results in ER retention and altered signaling by TNFR1 mutants in TNFR1-associated periodic fever syndrome (TRAPS)

Blood

Volumn 108, Issue 4, 2006, Pages 1320-1327

  Lobito, Adrian A ^b   Kimberley, Fiona C ^b   Muppidi, Jagan R ^b   Komarow, Hirsh ^b   Jackson, Adrianna J ^b   Hull, Keith M ^b   Kastner, Daniel L ^b   Screaton, Gavin R ^b   Siegel, Richard M ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MUTANT PROTEIN; OLIGOMER; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BIOLOGICAL ACTIVITY; CELL MEMBRANE; CONTROLLED STUDY; DISULFIDE BOND; ENDOPLASMIC RETICULUM; GENE MUTATION; GENETIC ASSOCIATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED PERIODIC SYNDROME;

EID: 33747162175     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2005-11-006783     Document Type: Article

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