Interleukin-36 (IL-36) ligands require processing for full agonist (IL-36α, IL-36β, and IL-36γ) or antagonist (IL-36Ra) activity

Journal of Biological Chemistry

Volumn 286, Issue 49, 2011, Pages 42594-42602

  Towne, Jennifer E ^a   Renshaw, Blair R ^a   Douangpanya, Jason ^a   Lipsky, Brian P ^a   Shen, Min ^a   Gabel, Christopher A ^a   Sims, John E ^a  

^a AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC RECEPTORS; CO-IMMUNOPRECIPITATIONS; EXTRACELLULAR; N-TERMINALS; POST-TRANSLATIONAL PROCESSING; PRE-TREATMENT; SIGNALING COMPLEX; SPECIFIC ACTIVITY;

EXPERIMENTS;

AMINO ACIDS;

ASPARTIC ACID; CYTOKINE; INTERLEUKIN 1 RACP; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 1 RRP2; INTERLEUKIN 36; INTERLEUKIN 36 ALPHA; INTERLEUKIN 36 BETA; INTERLEUKIN 36 GAMMA; INTERLEUKIN 36 RA; METHIONINE; UNCLASSIFIED DRUG; VALINE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CHIMERA; CONTROLLED STUDY; EXTRACELLULAR SPACE; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROCESSING;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CELL MEMBRANE; COS CELLS; HUMANS; INTERLEUKIN-1; INTERLEUKINS; JURKAT CELLS; LIGANDS; MICE; MOLECULAR SEQUENCE DATA; RECEPTORS, INTERLEUKIN-1; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 82755163088     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.267922     Document Type: Article

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