Identification of Protor as a novel Rictor-binding component of mTOR complex-2

Biochemical Journal

Volumn 405, Issue 3, 2007, Pages 513-522

  Pearce, Laura R ^a   Huang, Xu ^a   Boudeau, Jérôme ^a   Pawłowski, Rafał ^a   Wullschleger, Stephan ^a   Deak, Maria ^a   Ibrahim, Adel F M ^a   Gourlay, Robert ^a   Magnuson, Mark A ^b   Alessi, Dario R ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cancer; Mammalian target of rapamycin (mTOR); mTOR complex 2 (mTORC2); Proline rich repeat protein 5 (PRR 5); Protein kinase; Protein observed with Rictor 1 (Protor); Rapamycin insensitive companion of mTOR (Rictor)

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN (MTOR); MTOR COMPLEX-2 (MTORC2); PROLINE-RICH REPEAT PROTEIN-5 (PRR-5); PROTEIN KINASE; PROTEIN OBSERVED WITH RICTOR-1 (PROTOR); RAPAMYCIN-INSENSITIVE COMPANION OF MTOR (RICTOR);

CELL GROWTH; HYDROPHOBICITY; ONCOLOGY; PHOSPHORYLATION; PRECIPITATION (CHEMICAL);

PROTEINS;

BINDING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; PROTEIN MTORC2; PROTEIN PROTOR 1; PROTEIN PROTOR 2; RAPAMYCIN; REGULATOR PROTEIN; SOMATOMEDIN C; UNCLASSIFIED DRUG;

ARTICLE; CELL GROWTH; CELL STRAIN HEK293; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT;

CARRIER PROTEINS; CELL LINE; GENE SILENCING; HUMANS; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN KINASES;

MAMMALIA; RAPTORES;

EID: 34347210090     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20070540     Document Type: Article

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