-
1
-
-
0035856920
-
Global and societal implications of the diabetes epidemic
-
Zimmet P, Alberti KG, Shaw J Global and societal implications of the diabetes epidemic. Nature 2001, 414(6865):782-787.
-
(2001)
Nature
, vol.414
, Issue.6865
, pp. 782-787
-
-
Zimmet, P.1
Alberti, K.G.2
Shaw, J.3
-
2
-
-
2342466734
-
Global prevalence of diabetes: estimates for the year 2000 and projections for 2030
-
Wild S, Roglic G, Green A, Sicree R, King H Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004, 27(5):1047-1053.
-
(2004)
Diabetes Care
, vol.27
, Issue.5
, pp. 1047-1053
-
-
Wild, S.1
Roglic, G.2
Green, A.3
Sicree, R.4
King, H.5
-
3
-
-
0037219411
-
Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
-
Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes 2003, 52(1):102-110.
-
(2003)
Diabetes
, vol.52
, Issue.1
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
4
-
-
17044386953
-
Type 2 diabetes: principles of pathogenesis and therapy
-
Stumvoll M, Goldstein BJ, van Haeften TW Type 2 diabetes: principles of pathogenesis and therapy. Lancet 2005, 365(9467):1333-1346.
-
(2005)
Lancet
, vol.365
, Issue.9467
, pp. 1333-1346
-
-
Stumvoll, M.1
Goldstein, B.J.2
van Haeften, T.W.3
-
5
-
-
34249682591
-
Beta-cell failure in diabetes and preservation by clinical treatment
-
Wajchenberg BL beta-cell failure in diabetes and preservation by clinical treatment. Endocr Rev 2007, 28(2):187-218.
-
(2007)
Endocr Rev
, vol.28
, Issue.2
, pp. 187-218
-
-
Wajchenberg, B.L.1
-
6
-
-
0028813310
-
Risk of diabetes in offspring of parents with non-insulin-dependent diabetes
-
Pierce M, Keen H, Bradley C Risk of diabetes in offspring of parents with non-insulin-dependent diabetes. Diabet Med 1995, 12(1):1-6.
-
(1995)
Diabet Med
, vol.12
, Issue.1
, pp. 1-6
-
-
Pierce, M.1
Keen, H.2
Bradley, C.3
-
8
-
-
36849000396
-
Familiality of diabetes mellitus
-
Weires MB, Tausch B, Haug PJ, Edwards CQ, Wetter T, Cannon-Albright LA Familiality of diabetes mellitus. Exp Clin Endocrinol Diabetes 2007, 115(10):634-640.
-
(2007)
Exp Clin Endocrinol Diabetes
, vol.115
, Issue.10
, pp. 634-640
-
-
Weires, M.B.1
Tausch, B.2
Haug, P.J.3
Edwards, C.Q.4
Wetter, T.5
Cannon-Albright, L.A.6
-
9
-
-
0030884057
-
The genetics of human noninsulin-dependent (type 2) diabetes mellitus
-
Elbein SC The genetics of human noninsulin-dependent (type 2) diabetes mellitus. J Nutr 1997, 127(9):1891S-1896S.
-
(1997)
J Nutr
, vol.127
, Issue.9
-
-
Elbein, S.C.1
-
10
-
-
0030896748
-
The global epidemiology of non-insulin-dependent diabetes mellitus and the metabolic syndrome
-
Zimmet PZ, McCarty DJ, de Court The global epidemiology of non-insulin-dependent diabetes mellitus and the metabolic syndrome. J Diabetes Complications 1997, 11(2):60-68.
-
(1997)
J Diabetes Complications
, vol.11
, Issue.2
, pp. 60-68
-
-
Zimmet, P.Z.1
McCarty, D.J.2
de Court3
-
11
-
-
0018223157
-
Diabetes incidence and prevalence in Pima Indians: a 19-fold greater incidence than in Rochester, Minnesota
-
Knowler WC, Bennett PH, Hamman RF, Miller M Diabetes incidence and prevalence in Pima Indians: a 19-fold greater incidence than in Rochester, Minnesota. Am J Epidemiol 1978, 108(6):497-505.
-
(1978)
Am J Epidemiol
, vol.108
, Issue.6
, pp. 497-505
-
-
Knowler, W.C.1
Bennett, P.H.2
Hamman, R.F.3
Miller, M.4
-
12
-
-
43549084587
-
Monogenic diabetes in the young, pharmacogenetics and relevance to multifactorial forms of type 2 diabetes
-
Vaxillaire M, Froguel P Monogenic diabetes in the young, pharmacogenetics and relevance to multifactorial forms of type 2 diabetes. Endocr Rev 2008, 29(3):254-256.
-
(2008)
Endocr Rev
, vol.29
, Issue.3
, pp. 254-256
-
-
Vaxillaire, M.1
Froguel, P.2
-
13
-
-
0030688004
-
Variations on a theme: cataloging human DNA sequence variation
-
Collins FS, Guyer MS, Charkravarti A Variations on a theme: cataloging human DNA sequence variation. Science 1997, 278(5343):1580-1581.
-
(1997)
Science
, vol.278
, Issue.5343
, pp. 1580-1581
-
-
Collins, F.S.1
Guyer, M.S.2
Charkravarti, A.3
-
14
-
-
70849098773
-
Pathomechanisms of type 2 diabetes genes
-
Staiger H, Machicao F, Fritsche A, Haring HU Pathomechanisms of type 2 diabetes genes. Endocr Rev 2009, 30(6):557-585.
-
(2009)
Endocr Rev
, vol.30
, Issue.6
, pp. 557-585
-
-
Staiger, H.1
Machicao, F.2
Fritsche, A.3
Haring, H.U.4
-
15
-
-
33847176604
-
A genome-wide association study identifies novel risk loci for type 2 diabetes
-
Sladek R, Rocheleau G, Rung J, Dina C, Shen L, Serre D, et al. A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 2007, 445(7130):881-885.
-
(2007)
Nature
, vol.445
, Issue.7130
, pp. 881-885
-
-
Sladek, R.1
Rocheleau, G.2
Rung, J.3
Dina, C.4
Shen, L.5
Serre, D.6
-
16
-
-
0034728762
-
The Pro12Ala polymorphism in PPAR gamma2 may confer resistance to type 2 diabetes
-
Hara K, Okada T, Tobe K, Yasuda K, Mori Y, Kadowaki H, et al. The Pro12Ala polymorphism in PPAR gamma2 may confer resistance to type 2 diabetes. Biochem Biophys Res Commun 2000, 271(1):212-216.
-
(2000)
Biochem Biophys Res Commun
, vol.271
, Issue.1
, pp. 212-216
-
-
Hara, K.1
Okada, T.2
Tobe, K.3
Yasuda, K.4
Mori, Y.5
Kadowaki, H.6
-
17
-
-
3543008338
-
Candidate genes for type 2 diabetes
-
Parikh H, Groop L Candidate genes for type 2 diabetes. Rev Endocr Metab Disord 2004, 5(2):151-176.
-
(2004)
Rev Endocr Metab Disord
, vol.5
, Issue.2
, pp. 151-176
-
-
Parikh, H.1
Groop, L.2
-
18
-
-
0037312921
-
Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
-
Lohmueller KE, Pearce CL, Pike M, Lander ES, Hirschhorn JN Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet 2003, 33(2):177-182.
-
(2003)
Nat Genet
, vol.33
, Issue.2
, pp. 177-182
-
-
Lohmueller, K.E.1
Pearce, C.L.2
Pike, M.3
Lander, E.S.4
Hirschhorn, J.N.5
-
19
-
-
0036320603
-
The peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism
-
Stumvoll M, Haring H The peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism. Diabetes 2002, 51(8):2341-2347.
-
(2002)
Diabetes
, vol.51
, Issue.8
, pp. 2341-2347
-
-
Stumvoll, M.1
Haring, H.2
-
20
-
-
0037312864
-
The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes
-
Nielsen EM, Hansen L, Carstensen B, Echwald SM, Drivsholm T, Glumer C, et al. The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes. Diabetes 2003, 52(2):573-577.
-
(2003)
Diabetes
, vol.52
, Issue.2
, pp. 573-577
-
-
Nielsen, E.M.1
Hansen, L.2
Carstensen, B.3
Echwald, S.M.4
Drivsholm, T.5
Glumer, C.6
-
21
-
-
2342561802
-
Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region
-
Florez JC, Burtt N, de Bakker PI, Almgren P, Tuomi T, Holmkvist J, et al. Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region. Diabetes 2004, 53(5):1360-1368.
-
(2004)
Diabetes
, vol.53
, Issue.5
, pp. 1360-1368
-
-
Florez, J.C.1
Burtt, N.2
de Bakker, P.I.3
Almgren, P.4
Tuomi, T.5
Holmkvist, J.6
-
22
-
-
38449118682
-
Impact of common type 2 diabetes risk polymorphisms in the DESIR prospective study
-
Vaxillaire M, Veslot J, Dina C, Proenca C, Cauchi S, Charpentier G, et al. Impact of common type 2 diabetes risk polymorphisms in the DESIR prospective study. Diabetes 2008, 57(1):244-245.
-
(2008)
Diabetes
, vol.57
, Issue.1
, pp. 244-245
-
-
Vaxillaire, M.1
Veslot, J.2
Dina, C.3
Proenca, C.4
Cauchi, S.5
Charpentier, G.6
-
23
-
-
0033772073
-
Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
-
Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, Hara M, et al. Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet 2000, 26(2):163-175.
-
(2000)
Nat Genet
, vol.26
, Issue.2
, pp. 163-175
-
-
Horikawa, Y.1
Oda, N.2
Cox, N.J.3
Li, X.4
Orho-Melander, M.5
Hara, M.6
-
24
-
-
0034894047
-
Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom
-
Evans JC, Frayling TM, Cassell PG, Saker PJ, Hitman GA, Walker M, et al. Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom. Am J Hum Genet 2001, 69(3):544-552.
-
(2001)
Am J Hum Genet
, vol.69
, Issue.3
, pp. 544-552
-
-
Evans, J.C.1
Frayling, T.M.2
Cassell, P.G.3
Saker, P.J.4
Hitman, G.A.5
Walker, M.6
-
25
-
-
33746943663
-
Association of the calpain-10 gene with type 2 diabetes in Europeans: results of pooled and meta-analyses
-
Tsuchiya T, Schwarz PE, Bosque-Plata LD, Geoffrey HM, Dina C, Froguel P, et al. Association of the calpain-10 gene with type 2 diabetes in Europeans: results of pooled and meta-analyses. Mol Genet Metab 2006, 89(1-2):174-184.
-
(2006)
Mol Genet Metab
, vol.89
, Issue.1-2
, pp. 174-184
-
-
Tsuchiya, T.1
Schwarz, P.E.2
Bosque-Plata, L.D.3
Geoffrey, H.M.4
Dina, C.5
Froguel, P.6
-
26
-
-
33750622017
-
Variation in CAPN10 in relation to type 2 diabetes, obesity and quantitative metabolic traits: studies in 6018 whites
-
Jensen DP, Urhammer SA, Eiberg H, Borch-Johnsen K, Jorgensen T, Hansen T, et al. Variation in CAPN10 in relation to type 2 diabetes, obesity and quantitative metabolic traits: studies in 6018 whites. Mol Genet Metab 2006, 89(4):360-367.
-
(2006)
Mol Genet Metab
, vol.89
, Issue.4
, pp. 360-367
-
-
Jensen, D.P.1
Urhammer, S.A.2
Eiberg, H.3
Borch-Johnsen, K.4
Jorgensen, T.5
Hansen, T.6
-
27
-
-
25844490514
-
The K121Q polymorphism of the ENPP1/PC-1 gene is associated with insulin resistance/atherogenic phenotypes, including earlier onset of type 2 diabetes and myocardial infarction
-
Bacci S, Ludovico O, Prudente S, Zhang YY, Di Paola R, Mangiacotti D, et al. The K121Q polymorphism of the ENPP1/PC-1 gene is associated with insulin resistance/atherogenic phenotypes, including earlier onset of type 2 diabetes and myocardial infarction. Diabetes 2005, 54(10):3021-3025.
-
(2005)
Diabetes
, vol.54
, Issue.10
, pp. 3021-3025
-
-
Bacci, S.1
Ludovico, O.2
Prudente, S.3
Zhang, Y.Y.4
Di Paola, R.5
Mangiacotti, D.6
-
28
-
-
42449116149
-
The ENPP1 K121Q polymorphism is associated with type 2 diabetes in European populations: evidence from an updated meta-analysis in 42,042 subjects
-
McAteer JB, Prudente S, Bacci S, Lyon HN, Hirschhorn JN, Trischitta V, et al. The ENPP1 K121Q polymorphism is associated with type 2 diabetes in European populations: evidence from an updated meta-analysis in 42,042 subjects. Diabetes 2008, 57(4):1125-1130.
-
(2008)
Diabetes
, vol.57
, Issue.4
, pp. 1125-1130
-
-
McAteer, J.B.1
Prudente, S.2
Bacci, S.3
Lyon, H.N.4
Hirschhorn, J.N.5
Trischitta, V.6
-
29
-
-
48949088059
-
Effect of ENPP1/PC-1-K121Q and PPARgamma-Pro12Ala polymorphisms on the genetic susceptibility to T2D in the Tunisian population
-
Bouhaha R, Meyre D, Kamoun HA, Ennafaa H, Vaillant E, Sassi R, et al. Effect of ENPP1/PC-1-K121Q and PPARgamma-Pro12Ala polymorphisms on the genetic susceptibility to T2D in the Tunisian population. Diabetes Res Clin Pract 2008, 81(3):278-283.
-
(2008)
Diabetes Res Clin Pract
, vol.81
, Issue.3
, pp. 278-283
-
-
Bouhaha, R.1
Meyre, D.2
Kamoun, H.A.3
Ennafaa, H.4
Vaillant, E.5
Sassi, R.6
-
30
-
-
34249885875
-
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
-
Scott LJ, Mohlke KL, Bonnycastle LL, Wilier CJ, Li Y, Duren WL, et al. A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 2007, 316(5829):1341-1345.
-
(2007)
Science
, vol.316
, Issue.5829
, pp. 1341-1345
-
-
Scott, L.J.1
Mohlke, K.L.2
Bonnycastle, L.L.3
Wilier, C.J.4
Li, Y.5
Duren, W.L.6
-
31
-
-
34249888775
-
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
-
Saxena R, Voight BF, Lyssenko V, Burtt NP, de Bakker PI, Chen H, et al. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 2007, 316(5829):1331-1336.
-
(2007)
Science
, vol.316
, Issue.5829
, pp. 1331-1336
-
-
Saxena, R.1
Voight, B.F.2
Lyssenko, V.3
Burtt, N.P.4
de Bakker, P.I.5
Chen, H.6
-
32
-
-
34249895023
-
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
-
Zeggini E, Weedon MN, Lindgren CM, Frayling TM, Elliott KS, Lango H, et al. Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 2007, 316(5829):1336-1341.
-
(2007)
Science
, vol.316
, Issue.5829
, pp. 1336-1341
-
-
Zeggini, E.1
Weedon, M.N.2
Lindgren, C.M.3
Frayling, T.M.4
Elliott, K.S.5
Lango, H.6
-
33
-
-
55649105963
-
Clinical risk factors, DNA variants, and the development of type 2 diabetes
-
Lyssenko V, Jonsson A, Almgren P, Pulizzi N, Isomaa B, Tuomi T, et al. Clinical risk factors, DNA variants, and the development of type 2 diabetes. N Engl J Med 2008, 359(21):2220-2232.
-
(2008)
N Engl J Med
, vol.359
, Issue.21
, pp. 2220-2232
-
-
Lyssenko, V.1
Jonsson, A.2
Almgren, P.3
Pulizzi, N.4
Isomaa, B.5
Tuomi, T.6
-
34
-
-
42349106044
-
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
-
Zeggini E, Scott LJ, Saxena R, Voight BF, Marchini JL, Hu T, et al. Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 2008, 40(5):638-645.
-
(2008)
Nat Genet
, vol.40
, Issue.5
, pp. 638-645
-
-
Zeggini, E.1
Scott, L.J.2
Saxena, R.3
Voight, B.F.4
Marchini, J.L.5
Hu, T.6
-
35
-
-
0036061598
-
Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population
-
Hara K, Boutin P, Mori Y, Tobe K, Dina C, Yasuda K, et al. Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population. Diabetes 2002, 51(2):536-540.
-
(2002)
Diabetes
, vol.51
, Issue.2
, pp. 536-540
-
-
Hara, K.1
Boutin, P.2
Mori, Y.3
Tobe, K.4
Dina, C.5
Yasuda, K.6
-
36
-
-
20044384547
-
Hypoadiponectinaemia and high risk of type 2 diabetes are associated with adiponectin-encoding (ACDC) gene promoter variants in morbid obesity: evidence for a role of ACDC in diabesity
-
Vasseur F, Helbecque N, Lobbens S, Vasseur-Delannoy V, Dina C, Clement K, et al. Hypoadiponectinaemia and high risk of type 2 diabetes are associated with adiponectin-encoding (ACDC) gene promoter variants in morbid obesity: evidence for a role of ACDC in diabesity. Diabetologia 2005, 48(5):892-899.
-
(2005)
Diabetologia
, vol.48
, Issue.5
, pp. 892-899
-
-
Vasseur, F.1
Helbecque, N.2
Lobbens, S.3
Vasseur-Delannoy, V.4
Dina, C.5
Clement, K.6
-
37
-
-
33947583511
-
Common adiponectin gene variants show different effects on risk of cardiovascular disease and type 2 diabetes in European subjects
-
Gable DR, Matin J, Whittall R, Cakmak H, Li KW, Cooper J, et al. Common adiponectin gene variants show different effects on risk of cardiovascular disease and type 2 diabetes in European subjects. Ann Hum Genet 2007, 71(Pt4):453-466.
-
(2007)
Ann Hum Genet
, vol.71
, Issue.PART 4
, pp. 453-466
-
-
Gable, D.R.1
Matin, J.2
Whittall, R.3
Cakmak, H.4
Li, K.W.5
Cooper, J.6
-
38
-
-
63249086921
-
Association of adiponectin gene polymorphisms with type 2 diabetes in an African American population enriched for nephropathy
-
Bostrom MA, Freedman BI, Langefeld CD, Liu L, Hicks PJ, Bowden DW Association of adiponectin gene polymorphisms with type 2 diabetes in an African American population enriched for nephropathy. Diabetes 2009, 58(2):499-504.
-
(2009)
Diabetes
, vol.58
, Issue.2
, pp. 499-504
-
-
Bostrom, M.A.1
Freedman, B.I.2
Langefeld, C.D.3
Liu, L.4
Hicks, P.J.5
Bowden, D.W.6
-
39
-
-
10744222217
-
Genetic variants in human sterol regulatory element binding protein-1c in syndromes of severe insulin resistance and type 2 diabetes
-
Laudes M, Barroso I, Luan J, Soos MA, Yeo G, Meirhaeghe A, et al. Genetic variants in human sterol regulatory element binding protein-1c in syndromes of severe insulin resistance and type 2 diabetes. Diabetes 2004, 53(3):842-846.
-
(2004)
Diabetes
, vol.53
, Issue.3
, pp. 842-846
-
-
Laudes, M.1
Barroso, I.2
Luan, J.3
Soos, M.A.4
Yeo, G.5
Meirhaeghe, A.6
-
40
-
-
42449140190
-
Association of variants in the sterol regulatory element-binding factor 1 (SREBF1) gene with type 2 diabetes, glycemia, and insulin resistance: a study of 15,734 Danish subjects
-
Grarup N, Stender-Petersen KL, Andersson EA, Jorgensen T, Borch-Johnsen K, Sandbaek A, et al. Association of variants in the sterol regulatory element-binding factor 1 (SREBF1) gene with type 2 diabetes, glycemia, and insulin resistance: a study of 15,734 Danish subjects. Diabetes 2008, 57(4):1136-1142.
-
(2008)
Diabetes
, vol.57
, Issue.4
, pp. 1136-1142
-
-
Grarup, N.1
Stender-Petersen, K.L.2
Andersson, E.A.3
Jorgensen, T.4
Borch-Johnsen, K.5
Sandbaek, A.6
-
41
-
-
2342625303
-
Complex haplotypes of the PGC-1alpha gene are associated with carbohydrate metabolism and type 2 diabetes
-
Oberkofler H, Linnemayr V, Weitgasser R, Klein K, Xie M, Iglseder B, et al. Complex haplotypes of the PGC-1alpha gene are associated with carbohydrate metabolism and type 2 diabetes. Diabetes 2004, 53(5):1385-1393.
-
(2004)
Diabetes
, vol.53
, Issue.5
, pp. 1385-1393
-
-
Oberkofler, H.1
Linnemayr, V.2
Weitgasser, R.3
Klein, K.4
Xie, M.5
Iglseder, B.6
-
42
-
-
12944308811
-
Common polymorphisms of the PPAR-gamma2 (Pro12Ala) and PGC-1alpha (Gly482Ser) genes are associated with the conversion from impaired glucose tolerance to type 2 diabetes in the STOP-NIDDM trial
-
Andrulionyte L, Zacharova J, Chiasson JL, Laakso M Common polymorphisms of the PPAR-gamma2 (Pro12Ala) and PGC-1alpha (Gly482Ser) genes are associated with the conversion from impaired glucose tolerance to type 2 diabetes in the STOP-NIDDM trial. Diabetologia 2004, 47(12):2176-2184.
-
(2004)
Diabetologia
, vol.47
, Issue.12
, pp. 2176-2184
-
-
Andrulionyte, L.1
Zacharova, J.2
Chiasson, J.L.3
Laakso, M.4
-
43
-
-
33244465167
-
Meta-analysis of the Gly482Ser variant in PPARGC1A in type 2 diabetes and related phenotypes
-
Barroso I, Luan J, Sandhu MS, Franks PW, Crowley V, Schafer AJ, et al. Meta-analysis of the Gly482Ser variant in PPARGC1A in type 2 diabetes and related phenotypes. Diabetologia 2006, 49(3):501-505.
-
(2006)
Diabetologia
, vol.49
, Issue.3
, pp. 501-505
-
-
Barroso, I.1
Luan, J.2
Sandhu, M.S.3
Franks, P.W.4
Crowley, V.5
Schafer, A.J.6
-
44
-
-
42449113349
-
PPARGC1A variation associated with DNA damage, diabetes, and cardiovascular diseases: the Boston Puerto Rican Health Study
-
Lai CQ, Tucker KL, Parnell LD, Adiconis X, Garcia-Bailo B, Griffith J, et al. PPARGC1A variation associated with DNA damage, diabetes, and cardiovascular diseases: the Boston Puerto Rican Health Study. Diabetes 2008, 57(4):809-816.
-
(2008)
Diabetes
, vol.57
, Issue.4
, pp. 809-816
-
-
Lai, C.Q.1
Tucker, K.L.2
Parnell, L.D.3
Adiconis, X.4
Garcia-Bailo, B.5
Griffith, J.6
-
45
-
-
48449101972
-
AHSG tag single nucleotide polymorphisms associate with type 2 diabetes and dyslipidemia: studies of metabolic traits in 7,683 white Danish subjects
-
Andersen G, Burgdorf KS, Sparso T, Borch-Johnsen K, Jorgensen T, Hansen T, et al. AHSG tag single nucleotide polymorphisms associate with type 2 diabetes and dyslipidemia: studies of metabolic traits in 7,683 white Danish subjects. Diabetes 2008, 57(5):1427-1432.
-
(2008)
Diabetes
, vol.57
, Issue.5
, pp. 1427-1432
-
-
Andersen, G.1
Burgdorf, K.S.2
Sparso, T.3
Borch-Johnsen, K.4
Jorgensen, T.5
Hansen, T.6
-
46
-
-
23644433509
-
A synonymous coding polymorphism in the alpha2-Heremans-schmid glycoprotein gene is associated with type 2 diabetes in French Caucasians
-
Siddiq A, Lepretre F, Hercberg S, Froguel P, Gibson F A synonymous coding polymorphism in the alpha2-Heremans-schmid glycoprotein gene is associated with type 2 diabetes in French Caucasians. Diabetes 2005, 54(8):2477-2481.
-
(2005)
Diabetes
, vol.54
, Issue.8
, pp. 2477-2481
-
-
Siddiq, A.1
Lepretre, F.2
Hercberg, S.3
Froguel, P.4
Gibson, F.5
-
47
-
-
65249159171
-
Association of common genetic variation in the FOXO1 gene with beta-cell dysfunction, impaired glucose tolerance, and type 2 diabetes
-
Mussig K, Staiger H, Machicao F, Stancakova A, Kuusisto J, Laakso M, et al. Association of common genetic variation in the FOXO1 gene with beta-cell dysfunction, impaired glucose tolerance, and type 2 diabetes. J Clin Endocrinol Metab 2009, 94(4):1353-1360.
-
(2009)
J Clin Endocrinol Metab
, vol.94
, Issue.4
, pp. 1353-1360
-
-
Mussig, K.1
Staiger, H.2
Machicao, F.3
Stancakova, A.4
Kuusisto, J.5
Laakso, M.6
-
48
-
-
34548660801
-
A SNP haplotype of the forkhead transcription factor FOXO1A gene may have a protective effect against type 2 diabetes in German Caucasians
-
Bottcher Y, Tonjes A, Enigk B, Scholz GH, Bluher M, Stumvoll M, et al. A SNP haplotype of the forkhead transcription factor FOXO1A gene may have a protective effect against type 2 diabetes in German Caucasians. Diabetes Metab 2007, 33(4):277-283.
-
(2007)
Diabetes Metab
, vol.33
, Issue.4
, pp. 277-283
-
-
Bottcher, Y.1
Tonjes, A.2
Enigk, B.3
Scholz, G.H.4
Bluher, M.5
Stumvoll, M.6
-
49
-
-
56349099335
-
Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies
-
Friedrich B, Weyrich P, Stancakova A, Wang J, Kuusisto J, Laakso M, et al. Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies. PLoS ONE 2008, 3(11):e3506.
-
(2008)
PLoS ONE
, vol.3
, Issue.11
-
-
Friedrich, B.1
Weyrich, P.2
Stancakova, A.3
Wang, J.4
Kuusisto, J.5
Laakso, M.6
-
50
-
-
38349148734
-
Association of SGK1 gene polymorphisms with type 2 diabetes
-
Schwab M, Lupescu A, Mota M, Mota E, Frey A, Simon P, et al. Association of SGK1 gene polymorphisms with type 2 diabetes. Cell Physiol Biochem 2008, 21(1-3):151-160.
-
(2008)
Cell Physiol Biochem
, vol.21
, Issue.1-3
, pp. 151-160
-
-
Schwab, M.1
Lupescu, A.2
Mota, M.3
Mota, E.4
Frey, A.5
Simon, P.6
-
51
-
-
77949911881
-
Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes
-
Perry JR, Weedon MN, Langenberg C, Jackson AU, Lyssenko V, Sparso T, et al. Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes. Hum Mol Genet 2010, 19(3):535-544.
-
(2010)
Hum Mol Genet
, vol.19
, Issue.3
, pp. 535-544
-
-
Perry, J.R.1
Weedon, M.N.2
Langenberg, C.3
Jackson, A.U.4
Lyssenko, V.5
Sparso, T.6
-
52
-
-
70349235444
-
Sex hormone-binding globulin and risk of type 2 diabetes in women and men
-
Ding EL, Song Y, Manson JE, Hunter DJ, Lee CC, Rifai N, et al. Sex hormone-binding globulin and risk of type 2 diabetes in women and men. N Engl J Med 2009, 361(12):1152-1163.
-
(2009)
N Engl J Med
, vol.361
, Issue.12
, pp. 1152-1163
-
-
Ding, E.L.1
Song, Y.2
Manson, J.E.3
Hunter, D.J.4
Lee, C.C.5
Rifai, N.6
-
53
-
-
33750596924
-
Common variants in maturity-onset diabetes of the young genes contribute to risk of type 2 diabetes in Finns
-
Bonnycastle LL, Wilier CJ, Conneely KN, Jackson AU, Burrill CP, Watanabe RM, et al. Common variants in maturity-onset diabetes of the young genes contribute to risk of type 2 diabetes in Finns. Diabetes 2006, 55(9):2534-2540.
-
(2006)
Diabetes
, vol.55
, Issue.9
, pp. 2534-2540
-
-
Bonnycastle, L.L.1
Wilier, C.J.2
Conneely, K.N.3
Jackson, A.U.4
Burrill, C.P.5
Watanabe, R.M.6
-
54
-
-
33847361938
-
Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes
-
Winckler W, Weedon MN, Graham RR, McCarroll SA, Purcell S, Almgren P, et al. Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes. Diabetes 2007, 56(3):685-693.
-
(2007)
Diabetes
, vol.56
, Issue.3
, pp. 685-693
-
-
Winckler, W.1
Weedon, M.N.2
Graham, R.R.3
McCarroll, S.A.4
Purcell, S.5
Almgren, P.6
-
55
-
-
34547536393
-
Common variants in WFS1 confer risk of type 2 diabetes
-
Sandhu MS, Weedon MN, Fawcett KA, Wasson J, Debenham SL, Daly A, et al. Common variants in WFS1 confer risk of type 2 diabetes. Nat Genet 2007, 39(8):951-953.
-
(2007)
Nat Genet
, vol.39
, Issue.8
, pp. 951-953
-
-
Sandhu, M.S.1
Weedon, M.N.2
Fawcett, K.A.3
Wasson, J.4
Debenham, S.L.5
Daly, A.6
-
56
-
-
39049146958
-
Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations
-
Franks PW, Rolandsson O, Debenham SL, Fawcett KA, Payne F, Dina C, et al. Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations. Diabetologia 2008, 51(3):458-463.
-
(2008)
Diabetologia
, vol.51
, Issue.3
, pp. 458-463
-
-
Franks, P.W.1
Rolandsson, O.2
Debenham, S.L.3
Fawcett, K.A.4
Payne, F.5
Dina, C.6
-
57
-
-
32544451924
-
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
-
Grant SF, Thorleifsson G, Reynisdottir I, Benediktsson R, Manolescu A, Sainz J, et al. Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet 2006, 38(3):320-323.
-
(2006)
Nat Genet
, vol.38
, Issue.3
, pp. 320-323
-
-
Grant, S.F.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Manolescu, A.5
Sainz, J.6
-
58
-
-
33746075560
-
TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program
-
Florez JC, Jablonski KA, Bayley N, Pollin TI, de Bakker PI, Shuldiner AR, et al. TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program. N Engl J Med 2006, 355(3):241-250.
-
(2006)
N Engl J Med
, vol.355
, Issue.3
, pp. 241-250
-
-
Florez, J.C.1
Jablonski, K.A.2
Bayley, N.3
Pollin, T.I.4
de Bakker, P.I.5
Shuldiner, A.R.6
-
59
-
-
34447340935
-
TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis
-
Cauchi S, El Achhab Y, Choquet H, Dina C, Krempler F, Weitgasser R, et al. TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis. J Mol Med 2007, 85(7):777-782.
-
(2007)
J Mol Med
, vol.85
, Issue.7
, pp. 777-782
-
-
Cauchi, S.1
El Achhab, Y.2
Choquet, H.3
Dina, C.4
Krempler, F.5
Weitgasser, R.6
-
60
-
-
34447131039
-
Transcription factor 7-like 2 polymorphisms and type 2 diabetes, glucose homeostasis traits and gene expression in US participants of European and African descent
-
Elbein SC, Chu WS, Das SK, Yao-Borengasser A, Hasstedt SJ, Wang H, et al. Transcription factor 7-like 2 polymorphisms and type 2 diabetes, glucose homeostasis traits and gene expression in US participants of European and African descent. Diabetologia 2007, 50(8):1621-1630.
-
(2007)
Diabetologia
, vol.50
, Issue.8
, pp. 1621-1630
-
-
Elbein, S.C.1
Chu, W.S.2
Das, S.K.3
Yao-Borengasser, A.4
Hasstedt, S.J.5
Wang, H.6
-
61
-
-
63249118012
-
Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening
-
Tabara Y, Osawa H, Kawamoto R, Onuma H, Shimizu I, Miki T, et al. Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening. Diabetes 2009, 58(2):493-498.
-
(2009)
Diabetes
, vol.58
, Issue.2
, pp. 493-498
-
-
Tabara, Y.1
Osawa, H.2
Kawamoto, R.3
Onuma, H.4
Shimizu, I.5
Miki, T.6
-
62
-
-
44749085712
-
Newly identified loci highlight beta cell dysfunction as a key cause of type 2 diabetes: where are the insulin resistance genes?
-
Florez JC Newly identified loci highlight beta cell dysfunction as a key cause of type 2 diabetes: where are the insulin resistance genes?. Diabetologia 2008, 51(7):1100-1101.
-
(2008)
Diabetologia
, vol.51
, Issue.7
, pp. 1100-1101
-
-
Florez, J.C.1
-
63
-
-
40949087723
-
Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population
-
Omori S, Tanaka Y, Takahashi A, Hirose H, Kashiwagi A, Kaku K, et al. Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population. Diabetes 2008, 57(3):791-795.
-
(2008)
Diabetes
, vol.57
, Issue.3
, pp. 791-795
-
-
Omori, S.1
Tanaka, Y.2
Takahashi, A.3
Hirose, H.4
Kashiwagi, A.5
Kaku, K.6
-
64
-
-
50449104632
-
Implication of genetic variants nearTCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians
-
Ng MC, Park KS, Oh B, Tam CH, Cho YM, Shin HD, et al. Implication of genetic variants nearTCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians. Diabetes 2008, 57(8):2226-2233.
-
(2008)
Diabetes
, vol.57
, Issue.8
, pp. 2226-2233
-
-
Ng, M.C.1
Park, K.S.2
Oh, B.3
Tam, C.H.4
Cho, Y.M.5
Shin, H.D.6
-
65
-
-
36849011549
-
Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies
-
Grarup N, Rose CS, Andersson EA, Andersen G, Nielsen AL, Albrechtsen A, et al. Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies. Diabetes 2007, 56(12):3105-3111.
-
(2007)
Diabetes
, vol.56
, Issue.12
, pp. 3105-3111
-
-
Grarup, N.1
Rose, C.S.2
Andersson, E.A.3
Andersen, G.4
Nielsen, A.L.5
Albrechtsen, A.6
-
66
-
-
35848945259
-
Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population
-
Horikoshi M, Hara K, Ito C, Shojima N, Nagai R, Ueki K, et al. Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population. Diabetologia 2007, 50(12):2461-2466.
-
(2007)
Diabetologia
, vol.50
, Issue.12
, pp. 2461-2466
-
-
Horikoshi, M.1
Hara, K.2
Ito, C.3
Shojima, N.4
Nagai, R.5
Ueki, K.6
-
67
-
-
57349191471
-
Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population
-
Lee YH, Kang ES, Kim SH, Han SJ, Kim CH, Kim HJ, et al. Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population. J Hum Genet 2008, 53(11-12):991-998.
-
(2008)
J Hum Genet
, vol.53
, Issue.11-12
, pp. 991-998
-
-
Lee, Y.H.1
Kang, E.S.2
Kim, S.H.3
Han, S.J.4
Kim, C.H.5
Kim, H.J.6
-
68
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
Frayling TM, Timpson NJ, Weedon MN, Zeggini E, Freathy RM, Lindgren CM, et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007, 316(5826):889-894.
-
(2007)
Science
, vol.316
, Issue.5826
, pp. 889-894
-
-
Frayling, T.M.1
Timpson, N.J.2
Weedon, M.N.3
Zeggini, E.4
Freathy, R.M.5
Lindgren, C.M.6
-
69
-
-
67650655994
-
Replication study for the association of new meta-analysis-derived risk loci with susceptibility to type 2 diabetes in 6,244 Japanese individuals
-
Omori S, Tanaka Y, Horikoshi M, Takahashi A, Hara K, Hirose H, et al. Replication study for the association of new meta-analysis-derived risk loci with susceptibility to type 2 diabetes in 6,244 Japanese individuals. Diabetologia 2009, 52(8):1554-1560.
-
(2009)
Diabetologia
, vol.52
, Issue.8
, pp. 1554-1560
-
-
Omori, S.1
Tanaka, Y.2
Horikoshi, M.3
Takahashi, A.4
Hara, K.5
Hirose, H.6
-
70
-
-
70349833653
-
Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients-EUGENE2 study
-
Boesgaard TW, Gjesing AP, Grarup N, Rutanen J, Jansson PA, Hribal ML, et al. Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients-EUGENE2 study. PLoS ONE 2009, 4(9):e7236.
-
(2009)
PLoS ONE
, vol.4
, Issue.9
-
-
Boesgaard, T.W.1
Gjesing, A.P.2
Grarup, N.3
Rutanen, J.4
Jansson, P.A.5
Hribal, M.L.6
-
71
-
-
50449085212
-
SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations
-
Unoki H, Takahashi A, Kawaguchi T, Hara K, Horikoshi M, Andersen G, et al. SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. Nat Genet 2008, 40(9):1098-1102.
-
(2008)
Nat Genet
, vol.40
, Issue.9
, pp. 1098-1102
-
-
Unoki, H.1
Takahashi, A.2
Kawaguchi, T.3
Hara, K.4
Horikoshi, M.5
Andersen, G.6
-
72
-
-
50449085998
-
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
-
Yasuda K, Miyake K, Horikawa Y, Hara K, Osawa H, Furuta H, et al. Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Nat Genet 2008, 40(9):1092-1097.
-
(2008)
Nat Genet
, vol.40
, Issue.9
, pp. 1092-1097
-
-
Yasuda, K.1
Miyake, K.2
Horikawa, Y.3
Hara, K.4
Osawa, H.5
Furuta, H.6
-
73
-
-
67650251656
-
Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion
-
Mussig K, Staiger H, Machicao F, Kirchhoff K, Guthoff M, Schafer SA, et al. Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion. Diabetes 2009, 58(7):1715-1720.
-
(2009)
Diabetes
, vol.58
, Issue.7
, pp. 1715-1720
-
-
Mussig, K.1
Staiger, H.2
Machicao, F.3
Kirchhoff, K.4
Guthoff, M.5
Schafer, S.A.6
-
74
-
-
70349640785
-
A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion
-
Jonsson A, Isomaa B, Tuomi T, Taneera J, Salehi A, Nilsson P, et al. A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion. Diabetes 2009, 58(10):2409-2413.
-
(2009)
Diabetes
, vol.58
, Issue.10
, pp. 2409-2413
-
-
Jonsson, A.1
Isomaa, B.2
Tuomi, T.3
Taneera, J.4
Salehi, A.5
Nilsson, P.6
-
75
-
-
58149156287
-
Variants in MTNR1B influence fasting glucose levels
-
Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, et al. Variants in MTNR1B influence fasting glucose levels. Nat Genet 2009, 41(1):77-81.
-
(2009)
Nat Genet
, vol.41
, Issue.1
, pp. 77-81
-
-
Prokopenko, I.1
Langenberg, C.2
Florez, J.C.3
Saxena, R.4
Soranzo, N.5
Thorleifsson, G.6
-
76
-
-
58149175143
-
A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk
-
Bouatia-Naji N, Bonnefond A, Cavalcanti-Proenca C, Sparso T, Holmkvist J, Marchand M, et al. A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk. Nat Genet 2009, 41(1):89-94.
-
(2009)
Nat Genet
, vol.41
, Issue.1
, pp. 89-94
-
-
Bouatia-Naji, N.1
Bonnefond, A.2
Cavalcanti-Proenca, C.3
Sparso, T.4
Holmkvist, J.5
Marchand, M.6
-
77
-
-
58149175669
-
Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion
-
Lyssenko V, Nagorny CL, Erdos MR, Wierup N, Jonsson A, Spegel P, et al. Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion. Nat Genet 2009, 41(1):82-88.
-
(2009)
Nat Genet
, vol.41
, Issue.1
, pp. 82-88
-
-
Lyssenko, V.1
Nagorny, C.L.2
Erdos, M.R.3
Wierup, N.4
Jonsson, A.5
Spegel, P.6
-
78
-
-
67349224047
-
Melatonin receptors in pancreatic islets: good morning to a novel type 2 diabetes gene
-
Mulder H, Nagorny CL, Lyssenko V, Groop L Melatonin receptors in pancreatic islets: good morning to a novel type 2 diabetes gene. Diabetologia 2009, 52(7):1240-1249.
-
(2009)
Diabetologia
, vol.52
, Issue.7
, pp. 1240-1249
-
-
Mulder, H.1
Nagorny, C.L.2
Lyssenko, V.3
Groop, L.4
-
79
-
-
67650694101
-
Common genetic variation in the melatonin receptor 1B gene (MTNR1B) is associated with decreased early-phase insulin response
-
Langenberg C, Pascoe L, Mari A, Tura A, Laakso M, Frayling TM, et al. Common genetic variation in the melatonin receptor 1B gene (MTNR1B) is associated with decreased early-phase insulin response. Diabetologia 2009, 52(8):1537-1542.
-
(2009)
Diabetologia
, vol.52
, Issue.8
, pp. 1537-1542
-
-
Langenberg, C.1
Pascoe, L.2
Mari, A.3
Tura, A.4
Laakso, M.5
Frayling, T.M.6
-
80
-
-
58049198441
-
Polymorphisms within the novel type 2 diabetes risk locus MTNR1B determine beta-cell function
-
Staiger H, Machicao F, Schafer SA, Kirchhoff K, Kantartzis K, Guthoff M, et al. Polymorphisms within the novel type 2 diabetes risk locus MTNR1B determine beta-cell function. PLoS ONE 2008, 3(12):e3962.
-
(2008)
PLoS ONE
, vol.3
, Issue.12
-
-
Staiger, H.1
Machicao, F.2
Schafer, S.A.3
Kirchhoff, K.4
Kantartzis, K.5
Guthoff, M.6
-
81
-
-
70350542772
-
Common genetic variation near melatonin receptor MTNR1B contributes to raised plasma glucose and increased risk of type 2 diabetes among Indian Asians and European Caucasians
-
Chambers JC, Zhang W, Zabaneh D, Sehmi J, Jain P, McCarthy MI, et al. Common genetic variation near melatonin receptor MTNR1B contributes to raised plasma glucose and increased risk of type 2 diabetes among Indian Asians and European Caucasians. Diabetes 2009, 58(11):2703-2708.
-
(2009)
Diabetes
, vol.58
, Issue.11
, pp. 2703-2708
-
-
Chambers, J.C.1
Zhang, W.2
Zabaneh, D.3
Sehmi, J.4
Jain, P.5
McCarthy, M.I.6
-
82
-
-
64149094603
-
A common variant in MTNR1B, encoding melatonin receptor 1B, is associated with type 2 diabetes and fasting plasma glucose in Han Chinese individuals
-
Ronn T, Wen J, Yang Z, Lu B, Du Y, Groop L, et al. A common variant in MTNR1B, encoding melatonin receptor 1B, is associated with type 2 diabetes and fasting plasma glucose in Han Chinese individuals. Diabetologia 2009, 52(5):830-833.
-
(2009)
Diabetologia
, vol.52
, Issue.5
, pp. 830-833
-
-
Ronn, T.1
Wen, J.2
Yang, Z.3
Lu, B.4
Du, Y.5
Groop, L.6
-
83
-
-
34548032087
-
Genome-wide association studies provide new insights into type 2 diabetes aetiology
-
Frayling TM Genome-wide association studies provide new insights into type 2 diabetes aetiology. Nat Rev Genet 2007, 8(9):657-662.
-
(2007)
Nat Rev Genet
, vol.8
, Issue.9
, pp. 657-662
-
-
Frayling, T.M.1
-
84
-
-
70349557826
-
Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia
-
Rung J, Cauchi S, Albrechtsen A, Shen L, Rocheleau G, Cavalcanti-Proenca C, et al. Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. Nat Genet 2009, 41(10):1110-1115.
-
(2009)
Nat Genet
, vol.41
, Issue.10
, pp. 1110-1115
-
-
Rung, J.1
Cauchi, S.2
Albrechtsen, A.3
Shen, L.4
Rocheleau, G.5
Cavalcanti-Proenca, C.6
-
85
-
-
68449085627
-
Combined effects of single-nucleotide polymorphisms in GCK, GCKR, G6PC2 and MTNR1B on fasting plasma glucose and type 2 diabetes risk
-
Reiling E, van't RE, Groenewoud MJ, Welschen LM, van Hove EC, Nijpels G, et al. Combined effects of single-nucleotide polymorphisms in GCK, GCKR, G6PC2 and MTNR1B on fasting plasma glucose and type 2 diabetes risk. Diabetologia 2009, 52(9):1866-1870.
-
(2009)
Diabetologia
, vol.52
, Issue.9
, pp. 1866-1870
-
-
Reiling, E.1
van't, R.E.2
Groenewoud, M.J.3
Welschen, L.M.4
van Hove, E.C.5
Nijpels, G.6
-
86
-
-
44449091627
-
A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels
-
Bouatia-Naji N, Rocheleau G, Van Lommel L, Lemaire K, Schuit F, Cavalcanti-Proenca C, et al. A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels. Science 2008, 320(5879):1085-1088.
-
(2008)
Science
, vol.320
, Issue.5879
, pp. 1085-1088
-
-
Bouatia-Naji, N.1
Rocheleau, G.2
Van Lommel, L.3
Lemaire, K.4
Schuit, F.5
Cavalcanti-Proenca, C.6
-
87
-
-
70349980881
-
The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver
-
Beer NL, Tribble ND, McCulloch LJ, Roos C, Johnson PR, Orho-Melander M, et al. The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver. Hum Mol Genet 2009, 18(21):4081-4088.
-
(2009)
Hum Mol Genet
, vol.18
, Issue.21
, pp. 4081-4088
-
-
Beer, N.L.1
Tribble, N.D.2
McCulloch, L.J.3
Roos, C.4
Johnson, P.R.5
Orho-Melander, M.6
-
88
-
-
75749086085
-
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
-
Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010, 42(2):105-116.
-
(2010)
Nat Genet
, vol.42
, Issue.2
, pp. 105-116
-
-
Dupuis, J.1
Langenberg, C.2
Prokopenko, I.3
Saxena, R.4
Soranzo, N.5
Jackson, A.U.6
-
89
-
-
75749091912
-
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
-
Saxena R, Hivert MF, Langenberg C, Tanaka T, Pankow JS, Vollenweider P, et al. Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet 2010, 42(2):142-148.
-
(2010)
Nat Genet
, vol.42
, Issue.2
, pp. 142-148
-
-
Saxena, R.1
Hivert, M.F.2
Langenberg, C.3
Tanaka, T.4
Pankow, J.S.5
Vollenweider, P.6
-
90
-
-
0031595923
-
A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
-
Deeb SS, Fajas L, Nemoto M, Pihlajamaki J, Mykkanen L, Kuusisto J, et al. A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nat Genet 1998, 20(3):284-287.
-
(1998)
Nat Genet
, vol.20
, Issue.3
, pp. 284-287
-
-
Deeb, S.S.1
Fajas, L.2
Nemoto, M.3
Pihlajamaki, J.4
Mykkanen, L.5
Kuusisto, J.6
-
91
-
-
0037221208
-
Impact of two common polymorphisms in the PPARgamma gene on glucose tolerance and plasma insulin profiles in monozygotic and dizygotic twins: thrifty genotype, thrifty phenotype, or both?
-
Poulsen P, Andersen G, Fenger M, Hansen T, Echwald SM, Volund A, et al. Impact of two common polymorphisms in the PPARgamma gene on glucose tolerance and plasma insulin profiles in monozygotic and dizygotic twins: thrifty genotype, thrifty phenotype, or both?. Diabetes 2003, 52(1):194-198.
-
(2003)
Diabetes
, vol.52
, Issue.1
, pp. 194-198
-
-
Poulsen, P.1
Andersen, G.2
Fenger, M.3
Hansen, T.4
Echwald, S.M.5
Volund, A.6
-
92
-
-
33845472305
-
Association of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma with Pre-diabetic phenotypes: meta-analysis of 57 studies on nondiabetic individuals
-
Tonjes A, Scholz M, Loeffler M, Stumvoll M Association of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma with Pre-diabetic phenotypes: meta-analysis of 57 studies on nondiabetic individuals. Diabetes Care 2006, 29(11):2489-2497.
-
(2006)
Diabetes Care
, vol.29
, Issue.11
, pp. 2489-2497
-
-
Tonjes, A.1
Scholz, M.2
Loeffler, M.3
Stumvoll, M.4
-
93
-
-
0032589053
-
The PPARgamma2 amino acid polymorphism Pro 12 Ala is prevalent in offspring of Type II diabetic patients and is associated to increased insulin sensitivity in a subgroup of obese subjects
-
Koch M, Rett K, Maerker E, Volk A, Haist K, Deninger M, et al. The PPARgamma2 amino acid polymorphism Pro 12 Ala is prevalent in offspring of Type II diabetic patients and is associated to increased insulin sensitivity in a subgroup of obese subjects. Diabetologia 1999, 42(6):758-762.
-
(1999)
Diabetologia
, vol.42
, Issue.6
, pp. 758-762
-
-
Koch, M.1
Rett, K.2
Maerker, E.3
Volk, A.4
Haist, K.5
Deninger, M.6
-
94
-
-
0033797241
-
A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance
-
Baier LJ, Permana PA, Yang X, Pratley RE, Hanson RL, Shen GQ, et al. A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance. J Clin Invest 2000, 106(7):R69-R73.
-
(2000)
J Clin Invest
, vol.106
, Issue.7
-
-
Baier, L.J.1
Permana, P.A.2
Yang, X.3
Pratley, R.E.4
Hanson, R.L.5
Shen, G.Q.6
-
95
-
-
2942536810
-
Parallel manifestation of insulin resistance and beta cell decompensation is compatible with a common defect in Type 2 diabetes
-
Tripathy D, Eriksson KF, Orho-Melander M, Fredriksson J, Ahlqvist G, Groop L Parallel manifestation of insulin resistance and beta cell decompensation is compatible with a common defect in Type 2 diabetes. Diabetologia 2004, 47(5):782-793.
-
(2004)
Diabetologia
, vol.47
, Issue.5
, pp. 782-793
-
-
Tripathy, D.1
Eriksson, K.F.2
Orho-Melander, M.3
Fredriksson, J.4
Ahlqvist, G.5
Groop, L.6
-
96
-
-
51449104508
-
The CAPN10 gene is associated with insulin resistance phenotypes in the Spanish population
-
Saez ME, Gonzalez-Sanchez JL, Ramirez-Lorca R, Martinez-Larrad MT, Zabena C, Gonzalez A, et al. The CAPN10 gene is associated with insulin resistance phenotypes in the Spanish population. PLoS ONE 2008, 3(8):e2953.
-
(2008)
PLoS ONE
, vol.3
, Issue.8
-
-
Saez, M.E.1
Gonzalez-Sanchez, J.L.2
Ramirez-Lorca, R.3
Martinez-Larrad, M.T.4
Zabena, C.5
Gonzalez, A.6
-
97
-
-
0347993139
-
Genetic polymorphism PC-1 K121Q and ethnic susceptibility to insulin resistance
-
Abate N, Carulli L, Cabo-Chan A, Chandalia M, Snell PG, Grundy SM Genetic polymorphism PC-1 K121Q and ethnic susceptibility to insulin resistance. J Clin Endocrinol Metab 2003, 88(12):5927-5934.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, Issue.12
, pp. 5927-5934
-
-
Abate, N.1
Carulli, L.2
Cabo-Chan, A.3
Chandalia, M.4
Snell, P.G.5
Grundy, S.M.6
-
98
-
-
0041808862
-
The K121Q polymorphism of the PC-1 gene is associated with insulin resistance but not with dyslipidemia
-
Kubaszek A, Pihlajamaki J, Karhapaa P, Vauhkonen I, Laakso M The K121Q polymorphism of the PC-1 gene is associated with insulin resistance but not with dyslipidemia. Diabetes Care 2003, 26(2):464-467.
-
(2003)
Diabetes Care
, vol.26
, Issue.2
, pp. 464-467
-
-
Kubaszek, A.1
Pihlajamaki, J.2
Karhapaa, P.3
Vauhkonen, I.4
Laakso, M.5
-
99
-
-
34250627956
-
ENPP1 gene, insulin resistance and related clinical outcomes
-
Bacci S, De Cosmo S, Prudente S, Trischitta V ENPP1 gene, insulin resistance and related clinical outcomes. Curr Opin Clin Nutr Metab Care 2007, 10(4):403-409.
-
(2007)
Curr Opin Clin Nutr Metab Care
, vol.10
, Issue.4
, pp. 403-409
-
-
Bacci, S.1
De Cosmo, S.2
Prudente, S.3
Trischitta, V.4
-
100
-
-
48249098981
-
Haplotype structure of the ENPP1 Gene and Nominal Association of the K121Q missense single nucleotide polymorphism with glycemic traits in the Framingham Heart Study
-
Stolerman ES, Manning AK, McAteer JB, Dupuis J, Fox CS, Cupples LA, et al. Haplotype structure of the ENPP1 Gene and Nominal Association of the K121Q missense single nucleotide polymorphism with glycemic traits in the Framingham Heart Study. Diabetes 2008, 57(7):1971-1977.
-
(2008)
Diabetes
, vol.57
, Issue.7
, pp. 1971-1977
-
-
Stolerman, E.S.1
Manning, A.K.2
McAteer, J.B.3
Dupuis, J.4
Fox, C.S.5
Cupples, L.A.6
-
101
-
-
77949262297
-
The ENPP1 K121Q polymorphism determines individual susceptibility to the insulin-sensitising effect of lifestyle intervention
-
Mussig K, Heni M, Thamer C, Kantartzis K, Machicao F, Stefan N, et al. The ENPP1 K121Q polymorphism determines individual susceptibility to the insulin-sensitising effect of lifestyle intervention. Diabetologia 2010, 53(3):504-509.
-
(2010)
Diabetologia
, vol.53
, Issue.3
, pp. 504-509
-
-
Mussig, K.1
Heni, M.2
Thamer, C.3
Kantartzis, K.4
Machicao, F.5
Stefan, N.6
-
102
-
-
0036091918
-
Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes
-
Stumvoll M, Tschritter O, Fritsche A, Staiger H, Renn W, Weisser M, et al. Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes. Diabetes 2002, 51(1):37-41.
-
(2002)
Diabetes
, vol.51
, Issue.1
, pp. 37-41
-
-
Stumvoll, M.1
Tschritter, O.2
Fritsche, A.3
Staiger, H.4
Renn, W.5
Weisser, M.6
-
103
-
-
33847336953
-
The glucose clamp reveals an association between adiponectin gene polymorphisms and insulin sensitivity in obese subjects
-
Buzzetti R, Petrone A, Zavarella S, Zampetti S, Spoletini M, Potenziani S, et al. The glucose clamp reveals an association between adiponectin gene polymorphisms and insulin sensitivity in obese subjects. Int J Obes (Lond) 2007, 31(3):424-428.
-
(2007)
Int J Obes (Lond)
, vol.31
, Issue.3
, pp. 424-428
-
-
Buzzetti, R.1
Petrone, A.2
Zavarella, S.3
Zampetti, S.4
Spoletini, M.5
Potenziani, S.6
-
104
-
-
30444457098
-
The Gly482Ser missense mutation of the peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1 alpha) gene associates with reduced insulin sensitivity in normal and glucose-intolerant obese subjects
-
Fanelli M, Filippi E, Sentinelli F, Romeo S, Fallarino M, Buzzetti R, et al. The Gly482Ser missense mutation of the peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1 alpha) gene associates with reduced insulin sensitivity in normal and glucose-intolerant obese subjects. Dis Markers 2005, 21(4):175-180.
-
(2005)
Dis Markers
, vol.21
, Issue.4
, pp. 175-180
-
-
Fanelli, M.1
Filippi, E.2
Sentinelli, F.3
Romeo, S.4
Fallarino, M.5
Buzzetti, R.6
-
105
-
-
34249852535
-
Genetic variations in PPARD and PPARGC1A determine mitochondrial function and change in aerobic physical fitness and insulin sensitivity during lifestyle intervention
-
Stefan N, Thamer C, Staiger H, Machicao F, Machann J, Schick F, et al. Genetic variations in PPARD and PPARGC1A determine mitochondrial function and change in aerobic physical fitness and insulin sensitivity during lifestyle intervention. J Clin Endocrinol Metab 2007, 92(5):1827-1833.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, Issue.5
, pp. 1827-1833
-
-
Stefan, N.1
Thamer, C.2
Staiger, H.3
Machicao, F.4
Machann, J.5
Schick, F.6
-
106
-
-
12144256604
-
Alpha2-Heremans-Schmid glycoprotein gene polymorphisms are associated with adipocyte insulin action
-
Dahlman I, Eriksson P, Kaaman M, Jiao H, Lindgren CM, Kere J, et al. alpha2-Heremans-Schmid glycoprotein gene polymorphisms are associated with adipocyte insulin action. Diabetologia 2004, 47(11):1974-1979.
-
(2004)
Diabetologia
, vol.47
, Issue.11
, pp. 1974-1979
-
-
Dahlman, I.1
Eriksson, P.2
Kaaman, M.3
Jiao, H.4
Lindgren, C.M.5
Kere, J.6
-
107
-
-
33750584981
-
Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in the Amish: replication and evidence for a role in both insulin secretion and insulin resistance
-
Damcott CM, Pollin TI, Reinhart LJ, Ott SH, Shen H, Silver KD, et al. Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in the Amish: replication and evidence for a role in both insulin secretion and insulin resistance. Diabetes 2006, 55(9):2654-2659.
-
(2006)
Diabetes
, vol.55
, Issue.9
, pp. 2654-2659
-
-
Damcott, C.M.1
Pollin, T.I.2
Reinhart, L.J.3
Ott, S.H.4
Shen, H.5
Silver, K.D.6
-
108
-
-
34447248794
-
Targeted suppression of calpain-10 expression impairs insulin-stimulated glucose uptake in cultured primary human skeletal muscle cells
-
Brown AE, Yeaman SJ, Walker M Targeted suppression of calpain-10 expression impairs insulin-stimulated glucose uptake in cultured primary human skeletal muscle cells. Mol Genet Metab 2007, 91(4):318-324.
-
(2007)
Mol Genet Metab
, vol.91
, Issue.4
, pp. 318-324
-
-
Brown, A.E.1
Yeaman, S.J.2
Walker, M.3
-
109
-
-
0346725912
-
Calpain facilitates GLUT4 vesicle translocation during insulin-stimulated glucose uptake in adipocytes
-
Paul DS, Harmon AW, Winston CP, Patel YM Calpain facilitates GLUT4 vesicle translocation during insulin-stimulated glucose uptake in adipocytes. Biochem J 2003, 376(Pt3):625-632.
-
(2003)
Biochem J
, vol.376
, Issue.PART 3
, pp. 625-632
-
-
Paul, D.S.1
Harmon, A.W.2
Winston, C.P.3
Patel, Y.M.4
-
110
-
-
34447272464
-
Coordinated control of both insulin secretion and insulin action through calpain-10-mediated regulation of exocytosis?
-
Turner MD Coordinated control of both insulin secretion and insulin action through calpain-10-mediated regulation of exocytosis?. Mol Genet Metab 2007, 91(4):305-307.
-
(2007)
Mol Genet Metab
, vol.91
, Issue.4
, pp. 305-307
-
-
Turner, M.D.1
-
111
-
-
76749093118
-
Gene variants in the novel type 2 diabetes loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B affect different aspects of pancreatic beta-cell function
-
Simonis-Bik AM, Nijpels G, van Haeften van Haeften TW, Houwing-Duistermaat JJ, Boomsma DI, Reiling E, et al. Gene variants in the novel type 2 diabetes loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B affect different aspects of pancreatic beta-cell function. Diabetes 2010, 59(1):293-301.
-
(2010)
Diabetes
, vol.59
, Issue.1
, pp. 293-301
-
-
Simonis-Bik, A.M.1
Nijpels, G.2
van Haeften van Haeften, T.W.3
Houwing-Duistermaat, J.J.4
Boomsma, D.I.5
Reiling, E.6
-
112
-
-
50049119989
-
Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes
-
Grarup N, Andersen G, Krarup NT, Albrechtsen A, Schmitz O, Jorgensen T, et al. Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes. Diabetes 2008, 57(9):2534-2540.
-
(2008)
Diabetes
, vol.57
, Issue.9
, pp. 2534-2540
-
-
Grarup, N.1
Andersen, G.2
Krarup, N.T.3
Albrechtsen, A.4
Schmitz, O.5
Jorgensen, T.6
-
113
-
-
70349147046
-
Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men
-
Stancakova A, Kuulasmaa T, Paananen J, Jackson AU, Bonnycastle LL, Collins FS, et al. Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men. Diabetes 2009, 58(9):2129-2136.
-
(2009)
Diabetes
, vol.58
, Issue.9
, pp. 2129-2136
-
-
Stancakova, A.1
Kuulasmaa, T.2
Paananen, J.3
Jackson, A.U.4
Bonnycastle, L.L.5
Collins, F.S.6
-
114
-
-
51549112931
-
Novel meta-analysis-derived type 2 diabetes risk loci do not determine prediabetic phenotypes
-
Staiger H, Machicao F, Kantartzis K, Schafer SA, Kirchhoff K, Guthoff M, et al. Novel meta-analysis-derived type 2 diabetes risk loci do not determine prediabetic phenotypes. PLoS ONE 2008, 3(8):e3019.
-
(2008)
PLoS ONE
, vol.3
, Issue.8
-
-
Staiger, H.1
Machicao, F.2
Kantartzis, K.3
Schafer, S.A.4
Kirchhoff, K.5
Guthoff, M.6
-
115
-
-
61949437406
-
Transcription factor 7-like 2 polymorphism modulates glucose and lipid homeostasis, adipokine profile, and hepatocyte apoptosis in NASH
-
Musso G, Gambino R, Pacini G, Pagano G, Durazzo M, Cassader M Transcription factor 7-like 2 polymorphism modulates glucose and lipid homeostasis, adipokine profile, and hepatocyte apoptosis in NASH. Hepatology 2009, 49(2):426-435.
-
(2009)
Hepatology
, vol.49
, Issue.2
, pp. 426-435
-
-
Musso, G.1
Gambino, R.2
Pacini, G.3
Pagano, G.4
Durazzo, M.5
Cassader, M.6
-
116
-
-
0042814753
-
Increased insulin clearance in peroxisome proliferator-activated receptor gamma2 Pro12Ala
-
Tschritter O, Fritsche A, Stefan N, Haap M, Thamer C, Bachmann O, et al. Increased insulin clearance in peroxisome proliferator-activated receptor gamma2 Pro12Ala. Metabolism 2003, 52(6):778-783.
-
(2003)
Metabolism
, vol.52
, Issue.6
, pp. 778-783
-
-
Tschritter, O.1
Fritsche, A.2
Stefan, N.3
Haap, M.4
Thamer, C.5
Bachmann, O.6
-
117
-
-
0033957339
-
Membrane glycoprotein PC-1 inhibition of insulin receptor function occurs via direct interaction with the receptor alpha-subunit
-
Maddux BA, Goldfine ID Membrane glycoprotein PC-1 inhibition of insulin receptor function occurs via direct interaction with the receptor alpha-subunit. Diabetes 2000, 49(1):13-19.
-
(2000)
Diabetes
, vol.49
, Issue.1
, pp. 13-19
-
-
Maddux, B.A.1
Goldfine, I.D.2
-
118
-
-
11144250219
-
Multigenic control of serum adiponectin levels: evidence for a role of the APM1 gene and a locus on 14ql3
-
Menzaghi C, Ercolino T, Salvemini L, Coco A, Kim SH, Fini G, et al. Multigenic control of serum adiponectin levels: evidence for a role of the APM1 gene and a locus on 14ql3. Physiol Genomics 2004, 19(2):170-174.
-
(2004)
Physiol Genomics
, vol.19
, Issue.2
, pp. 170-174
-
-
Menzaghi, C.1
Ercolino, T.2
Salvemini, L.3
Coco, A.4
Kim, S.H.5
Fini, G.6
-
119
-
-
17844362260
-
The +276 polymorphism of the APM1 gene, plasma adiponectin concentration, and cardiovascular risk in diabetic men
-
Qi L, Li T, Rimm E, Zhang C, Rifai N, Hunter D, et al. The +276 polymorphism of the APM1 gene, plasma adiponectin concentration, and cardiovascular risk in diabetic men. Diabetes 2005, 54(5):1607-1610.
-
(2005)
Diabetes
, vol.54
, Issue.5
, pp. 1607-1610
-
-
Qi, L.1
Li, T.2
Rimm, E.3
Zhang, C.4
Rifai, N.5
Hunter, D.6
-
120
-
-
33644745284
-
Interactions between noncontiguous haplotypes in the adiponectin gene ACDC are associated with plasma adiponectin
-
Woo JG, Dolan LM, Deka R, Kaushal RD, Shen Y, Pal P, et al. Interactions between noncontiguous haplotypes in the adiponectin gene ACDC are associated with plasma adiponectin. Diabetes 2006, 55(2):523-529.
-
(2006)
Diabetes
, vol.55
, Issue.2
, pp. 523-529
-
-
Woo, J.G.1
Dolan, L.M.2
Deka, R.3
Kaushal, R.D.4
Shen, Y.5
Pal, P.6
-
121
-
-
33845592201
-
Adipose tissue-derived factors: impact on health and disease
-
Trujillo ME, Scherer PE Adipose tissue-derived factors: impact on health and disease. Endocr Rev 2006, 27(7):762-778.
-
(2006)
Endocr Rev
, vol.27
, Issue.7
, pp. 762-778
-
-
Trujillo, M.E.1
Scherer, P.E.2
-
122
-
-
18844432308
-
Adiponectin and adiponectin receptors
-
Kadowaki T, Yamauchi T Adiponectin and adiponectin receptors. Endocr Rev 2005, 26(3):439-451.
-
(2005)
Endocr Rev
, vol.26
, Issue.3
, pp. 439-451
-
-
Kadowaki, T.1
Yamauchi, T.2
-
123
-
-
33749135225
-
The relationships of plasma adiponectin with a favorable lipid profile, decreased inflammation, and less ectopic fat accumulation depend on adiposity
-
Kantartzis K, Rittig K, Balletshofer B, Machann J, Schick F, Porubska K, et al. The relationships of plasma adiponectin with a favorable lipid profile, decreased inflammation, and less ectopic fat accumulation depend on adiposity. Clin Chem 2006, 52(10):1934-1942.
-
(2006)
Clin Chem
, vol.52
, Issue.10
, pp. 1934-1942
-
-
Kantartzis, K.1
Rittig, K.2
Balletshofer, B.3
Machann, J.4
Schick, F.5
Porubska, K.6
-
124
-
-
58849105826
-
Adiponectin oligomers and ectopic fat in liver and skeletal muscle in humans
-
Kantartzis K, Staiger H, Machann J, Schick F, Claussen CD, Machicao F, et al. Adiponectin oligomers and ectopic fat in liver and skeletal muscle in humans. Obesity (Silver Spring) 2009, 17(2):390-392.
-
(2009)
Obesity (Silver Spring)
, vol.17
, Issue.2
, pp. 390-392
-
-
Kantartzis, K.1
Staiger, H.2
Machann, J.3
Schick, F.4
Claussen, C.D.5
Machicao, F.6
-
125
-
-
33745298222
-
Regulation of fat metabolism in the liver: link to non-alcoholic hepatic steatosis and impact of physical exercise
-
Lavoie JM, Gauthier MS Regulation of fat metabolism in the liver: link to non-alcoholic hepatic steatosis and impact of physical exercise. Cell Mol Life Sei 2006, 63(12):1393-1409.
-
(2006)
Cell Mol Life Sei
, vol.63
, Issue.12
, pp. 1393-1409
-
-
Lavoie, J.M.1
Gauthier, M.S.2
-
126
-
-
57349116780
-
Causes and metabolic consequences of fatty liver
-
Stefan N, Kantartzis K, Haring HU Causes and metabolic consequences of fatty liver. Endocr Rev 2008, 29(7):939-960.
-
(2008)
Endocr Rev
, vol.29
, Issue.7
, pp. 939-960
-
-
Stefan, N.1
Kantartzis, K.2
Haring, H.U.3
-
127
-
-
0038054341
-
PGC-lalpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, et al. PGC-lalpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 2003, 34(3):267-273.
-
(2003)
Nat Genet
, vol.34
, Issue.3
, pp. 267-273
-
-
Mootha, V.K.1
Lindgren, C.M.2
Eriksson, K.F.3
Subramanian, A.4
Sihag, S.5
Lehar, J.6
-
128
-
-
41949114990
-
Role of mitochondrial dysfunction in insulin resistance
-
Kim JA, Wei Y, Sowers JR Role of mitochondrial dysfunction in insulin resistance. Circ Res 2008, 102(4):401-414.
-
(2008)
Circ Res
, vol.102
, Issue.4
, pp. 401-414
-
-
Kim, J.A.1
Wei, Y.2
Sowers, J.R.3
-
129
-
-
68849104744
-
High cardiorespiratory fitness is an independent predictor of the reduction in liver fat during a lifestyle intervention in non-alcoholic fatty liver disease
-
Kantartzis K, Thamer C, Peter A, Machann J, Schick F, Schraml C, et al. High cardiorespiratory fitness is an independent predictor of the reduction in liver fat during a lifestyle intervention in non-alcoholic fatty liver disease. Gut 2009, 58(9):1281-1288.
-
(2009)
Gut
, vol.58
, Issue.9
, pp. 1281-1288
-
-
Kantartzis, K.1
Thamer, C.2
Peter, A.3
Machann, J.4
Schick, F.5
Schraml, C.6
-
130
-
-
50449084335
-
Mitochondrial dysfunction in type 2 diabetes and obesity
-
Hojlund K, Mogensen M, Sahlin K, Beck-Nielsen H Mitochondrial dysfunction in type 2 diabetes and obesity. Endocrinol Metab Clin North Am 2008, 37(3):713-731.
-
(2008)
Endocrinol Metab Clin North Am
, vol.37
, Issue.3
, pp. 713-731
-
-
Hojlund, K.1
Mogensen, M.2
Sahlin, K.3
Beck-Nielsen, H.4
-
131
-
-
70350469295
-
AHSG gene variation is not associated with regional body fat distribution - a magnetic resonance study
-
Mussig K, Staiger H, Machicao F, Machann J, Hennige AM, Schick F, et al. AHSG gene variation is not associated with regional body fat distribution - a magnetic resonance study. Exp Clin Endocrinol Diabetes 2009, 117(8):432-437.
-
(2009)
Exp Clin Endocrinol Diabetes
, vol.117
, Issue.8
, pp. 432-437
-
-
Mussig, K.1
Staiger, H.2
Machicao, F.3
Machann, J.4
Hennige, A.M.5
Schick, F.6
-
132
-
-
33746367157
-
Alpha2-Heremans-Schmid glycoprotein/fetuin-A is associated with insulin resistance and fat accumulation in the liver in humans
-
Stefan N, Hennige AM, Staiger H, Machann J, Schick F, Krober SM, et al. Alpha2-Heremans-Schmid glycoprotein/fetuin-A is associated with insulin resistance and fat accumulation in the liver in humans. Diabetes Care 2006, 29(4):853-857.
-
(2006)
Diabetes Care
, vol.29
, Issue.4
, pp. 853-857
-
-
Stefan, N.1
Hennige, A.M.2
Staiger, H.3
Machann, J.4
Schick, F.5
Krober, S.M.6
-
133
-
-
56649094538
-
Plasma fetuin-A levels and the risk of type 2 diabetes
-
Stefan N, Fritsche A, Weikert C, Boeing H, Joost HG, Haring HU, et al. Plasma fetuin-A levels and the risk of type 2 diabetes. Diabetes 2008, 57(10):2762-2767.
-
(2008)
Diabetes
, vol.57
, Issue.10
, pp. 2762-2767
-
-
Stefan, N.1
Fritsche, A.2
Weikert, C.3
Boeing, H.4
Joost, H.G.5
Haring, H.U.6
-
134
-
-
58149393662
-
Plasma fetuin-a levels and the risk of myocardial infarction and ischemie stroke
-
Weikert C, Stefan N, Schulze MB, Pischon T, Berger K, Joost HG, et al. Plasma fetuin-a levels and the risk of myocardial infarction and ischemie stroke. Circulation 2008, 118(24):2555-2562.
-
(2008)
Circulation
, vol.118
, Issue.24
, pp. 2555-2562
-
-
Weikert, C.1
Stefan, N.2
Schulze, M.B.3
Pischon, T.4
Berger, K.5
Joost, H.G.6
-
135
-
-
47049126504
-
Fetuin-A and incident diabetes mellitus in older persons
-
Ix JH, Wassel CL, Kanaya AM, Vittinghoff E, Johnson KC, Koster A, et al. Fetuin-A and incident diabetes mellitus in older persons. JAMA 2008, 300(2):182-188.
-
(2008)
JAMA
, vol.300
, Issue.2
, pp. 182-188
-
-
Ix, J.H.1
Wassel, C.L.2
Kanaya, A.M.3
Vittinghoff, E.4
Johnson, K.C.5
Koster, A.6
-
136
-
-
77449147603
-
Association of AHSG gene polymorphisms with fetuin-A plasma levels and cardiovascular diseases in the EPIC-Potsdam study
-
Fisher E, Stefan N, Saar K, Drogan D, Schulze MB, Fritsche A, et al. Association of AHSG gene polymorphisms with fetuin-A plasma levels and cardiovascular diseases in the EPIC-Potsdam study. Circ Cardiovasc Genet 2009, 2(6):607-613.
-
(2009)
Circ Cardiovasc Genet
, vol.2
, Issue.6
, pp. 607-613
-
-
Fisher, E.1
Stefan, N.2
Saar, K.3
Drogan, D.4
Schulze, M.B.5
Fritsche, A.6
-
137
-
-
38449098674
-
Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation
-
Andreasen CH, Stender-Petersen KL, Mogensen MS, Torekov SS, Wegner L, Andersen G, et al. Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation. Diabetes 2008, 57(1):10-95.
-
(2008)
Diabetes
, vol.57
, Issue.1
, pp. 10-95
-
-
Andreasen, C.H.1
Stender-Petersen, K.L.2
Mogensen, M.S.3
Torekov, S.S.4
Wegner, L.5
Andersen, G.6
-
138
-
-
48749097565
-
Impact of variation in the FTO gene on whole body fat distribution, ectopic fat, and weight loss
-
Haupt A, Thamer C, Machann J, Kirchhoff K, Stefan N, Tschritter O, et al. Impact of variation in the FTO gene on whole body fat distribution, ectopic fat, and weight loss. Obesity (Silver Spring) 2008, 16(8):1969-1972.
-
(2008)
Obesity (Silver Spring)
, vol.16
, Issue.8
, pp. 1969-1972
-
-
Haupt, A.1
Thamer, C.2
Machann, J.3
Kirchhoff, K.4
Stefan, N.5
Tschritter, O.6
-
139
-
-
34249777814
-
Variation in FTO contributes to childhood obesity and severe adult obesity
-
Dina C, Meyre D, Gallina S, Durand E, Korner A, Jacobson P, et al. Variation in FTO contributes to childhood obesity and severe adult obesity. Nat Genet 2007, 39(6):724-726.
-
(2007)
Nat Genet
, vol.39
, Issue.6
, pp. 724-726
-
-
Dina, C.1
Meyre, D.2
Gallina, S.3
Durand, E.4
Korner, A.5
Jacobson, P.6
-
140
-
-
42449153273
-
Genetic variants of FTO influence adiposity, insulin sensitivity, leptin levels, and resting metabolic rate in the Quebec Family Study
-
Do R, Bailey SD, Desbiens K, Belisle A, Montpetit A, Bouchard C, et al. Genetic variants of FTO influence adiposity, insulin sensitivity, leptin levels, and resting metabolic rate in the Quebec Family Study. Diabetes 2008, 57(4):1147-1150.
-
(2008)
Diabetes
, vol.57
, Issue.4
, pp. 1147-1150
-
-
Do, R.1
Bailey, S.D.2
Desbiens, K.3
Belisle, A.4
Montpetit, A.5
Bouchard, C.6
-
141
-
-
48249100977
-
Association of FTO with obesity-related traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) Cohort
-
Marvelle AF, Lange LA, Qin L, Adair LS, Mohlke KL Association of FTO with obesity-related traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) Cohort. Diabetes 2008, 57(7):1987-1991.
-
(2008)
Diabetes
, vol.57
, Issue.7
, pp. 1987-1991
-
-
Marvelle, A.F.1
Lange, L.A.2
Qin, L.3
Adair, L.S.4
Mohlke, K.L.5
-
142
-
-
67649852402
-
Variation in the FTO gene influences food intake but not energy expenditure
-
Haupt A, Thamer C, Staiger H, Tschritter O, Kirchhoff K, Machicao F, et al. Variation in the FTO gene influences food intake but not energy expenditure. Exp Clin Endocrinol Diabetes 2009, 117(4):194-197.
-
(2009)
Exp Clin Endocrinol Diabetes
, vol.117
, Issue.4
, pp. 194-197
-
-
Haupt, A.1
Thamer, C.2
Staiger, H.3
Tschritter, O.4
Kirchhoff, K.5
Machicao, F.6
-
143
-
-
36749041363
-
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase
-
Gerken T, Girard CA, Tung YC, Webby CJ, Saudek V, Hewitson KS, et al. The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science 2007, 318(5855):1469-1472.
-
(2007)
Science
, vol.318
, Issue.5855
, pp. 1469-1472
-
-
Gerken, T.1
Girard, C.A.2
Tung, Y.C.3
Webby, C.J.4
Saudek, V.5
Hewitson, K.S.6
-
144
-
-
51649128621
-
Obesity associated genetic variation in FTO is associated with diminished satiety
-
Wardle J, Carnell S, Haworth CM, Farooqi IS, O'Rahilly S, Plomin R Obesity associated genetic variation in FTO is associated with diminished satiety. J Clin Endocrinol Metab 2008, 93(9):3640-3643.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, Issue.9
, pp. 3640-3643
-
-
Wardle, J.1
Carnell, S.2
Haworth, C.M.3
Farooqi, I.S.4
O'Rahilly, S.5
Plomin, R.6
-
145
-
-
57749121512
-
An obesity-associated FTO gene variant and increased energy intake in children
-
Cecil JE, Tavendale R, Watt P, Hetherington MM, Palmer CN An obesity-associated FTO gene variant and increased energy intake in children. N Engl J Med 2008, 359(24):2558-2566.
-
(2008)
N Engl J Med
, vol.359
, Issue.24
, pp. 2558-2566
-
-
Cecil, J.E.1
Tavendale, R.2
Watt, P.3
Hetherington, M.M.4
Palmer, C.N.5
-
146
-
-
35848938196
-
Variation in the FTO gene locus is associated with cerebrocortical insulin resistance in humans
-
Tschritter O, Preissl H, Yokoyama Y, Machicao F, Haring HU, Fritsche A Variation in the FTO gene locus is associated with cerebrocortical insulin resistance in humans. Diabetologia 2007, 50(12):2602-2603.
-
(2007)
Diabetologia
, vol.50
, Issue.12
, pp. 2602-2603
-
-
Tschritter, O.1
Preissl, H.2
Yokoyama, Y.3
Machicao, F.4
Haring, H.U.5
Fritsche, A.6
-
147
-
-
44349142294
-
Common variants near MC4R are associated with fat mass, weight and risk of obesity
-
Loos RJ, Lindgren CM, Li S, Wheeler E, Zhao JH, Prokopenko I, et al. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet 2008, 40(6):768-775.
-
(2008)
Nat Genet
, vol.40
, Issue.6
, pp. 768-775
-
-
Loos, R.J.1
Lindgren, C.M.2
Li, S.3
Wheeler, E.4
Zhao, J.H.5
Prokopenko, I.6
-
148
-
-
58149163142
-
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
-
Wilier CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM, et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2009, 41(1):25-34.
-
(2009)
Nat Genet
, vol.41
, Issue.1
, pp. 25-34
-
-
Wilier, C.J.1
Speliotes, E.K.2
Loos, R.J.3
Li, S.4
Lindgren, C.M.5
Heid, I.M.6
-
149
-
-
58149163141
-
Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity
-
Thorleifsson G, Walters GB, Gudbjartsson DF, Steinthorsdottir V, Sulem P, Helgadottir A, et al. Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat Genet 2009, 41(1):18-24.
-
(2009)
Nat Genet
, vol.41
, Issue.1
, pp. 18-24
-
-
Thorleifsson, G.1
Walters, G.B.2
Gudbjartsson, D.F.3
Steinthorsdottir, V.4
Sulem, P.5
Helgadottir, A.6
-
150
-
-
0036868797
-
Glucose-stimulated signaling pathways in biphasic insulin secretion
-
Straub SG, Sharp GW Glucose-stimulated signaling pathways in biphasic insulin secretion. Diabetes Metab Res Rev 2002, 18(6):451-463.
-
(2002)
Diabetes Metab Res Rev
, vol.18
, Issue.6
, pp. 451-463
-
-
Straub, S.G.1
Sharp, G.W.2
-
151
-
-
0036310679
-
Triggering and augmentation mechanisms, granule pools, and biphasic insulin secretion
-
Bratanova-Tochkova TK, Cheng H, Daniel S, Gunawardana S, Liu YJ, Mulvaney-Musa J, et al. Triggering and augmentation mechanisms, granule pools, and biphasic insulin secretion. Diabetes 2002, 51(Suppl 1):S83-S90.
-
(2002)
Diabetes
, vol.51
, Issue.SUPPL. 1
-
-
Bratanova-Tochkova, T.K.1
Cheng, H.2
Daniel, S.3
Gunawardana, S.4
Liu, Y.J.5
Mulvaney-Musa, J.6
-
152
-
-
64149126546
-
Regulation of insulin secretion: a matter of phase control and amplitude modulation
-
Henquin JC Regulation of insulin secretion: a matter of phase control and amplitude modulation. Diabetologia 2009, 52(5):739-751.
-
(2009)
Diabetologia
, vol.52
, Issue.5
, pp. 739-751
-
-
Henquin, J.C.1
-
153
-
-
0026473236
-
Cellular and molecular biology of the beta cell
-
Steiner DF, James DE Cellular and molecular biology of the beta cell. Diabetologia 1992, 35(Suppl 2):S41-S48.
-
(1992)
Diabetologia
, vol.35
, Issue.SUPPL. 2
-
-
Steiner, D.F.1
James, D.E.2
-
154
-
-
0031791047
-
Disproportionately elevated proinsulin levels reflect the degree of impaired B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus
-
Roder ME, Porte D, Schwartz RS, Kahn SE Disproportionately elevated proinsulin levels reflect the degree of impaired B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 1998, 83(2):604-608.
-
(1998)
J Clin Endocrinol Metab
, vol.83
, Issue.2
, pp. 604-608
-
-
Roder, M.E.1
Porte, D.2
Schwartz, R.S.3
Kahn, S.E.4
-
155
-
-
0034678739
-
The importance of the beta-cell in the pathogenesis of type 2 diabetes mellitus
-
Kahn SE The importance of the beta-cell in the pathogenesis of type 2 diabetes mellitus. Am J Med 2000, 108(Suppl 6a):2S-8S.
-
(2000)
Am J Med
, vol.108
, Issue.SUPPL. 6A
-
-
Kahn, S.E.1
-
156
-
-
18644376240
-
Type 2 diabetes, insulin secretion and beta-cell mass
-
Ahren B Type 2 diabetes, insulin secretion and beta-cell mass. Curr Mol Med 2005, 5(3):275-286.
-
(2005)
Curr Mol Med
, vol.5
, Issue.3
, pp. 275-286
-
-
Ahren, B.1
-
157
-
-
33845881411
-
Mechanisms linking obesity to insulin resistance and type 2 diabetes
-
Kahn SE, Hull RL, Utzschneider KM Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 2006, 444(7121):840-846.
-
(2006)
Nature
, vol.444
, Issue.7121
, pp. 840-846
-
-
Kahn, S.E.1
Hull, R.L.2
Utzschneider, K.M.3
-
158
-
-
33846679496
-
Pancreatic islet cell therapy for type I diabetes: understanding the effects of glucose stimulation on islets in order to produce better islets for transplantation
-
Ren J, Jin P, Wang E, Liu E, Harlan DM, Li X, et al. Pancreatic islet cell therapy for type I diabetes: understanding the effects of glucose stimulation on islets in order to produce better islets for transplantation. J Transi Med 2007, 5:1.
-
(2007)
J Transi Med
, vol.5
, pp. 1
-
-
Ren, J.1
Jin, P.2
Wang, E.3
Liu, E.4
Harlan, D.M.5
Li, X.6
-
159
-
-
61349111509
-
Insulin granule biogenesis, trafficking and exocytosis
-
Hou JC, Min L, Pessin JE Insulin granule biogenesis, trafficking and exocytosis. Vitam Horm 2009, 80:473-506.
-
(2009)
Vitam Horm
, vol.80
, pp. 473-506
-
-
Hou, J.C.1
Min, L.2
Pessin, J.E.3
-
160
-
-
0028859374
-
Human and rat beta cells differ in glucose transporter but not in glucokinase gene expression
-
De Vos A, Heimberg H, Quartier E, Huypens P, Bouwens L, Pipeleers D, et al. Human and rat beta cells differ in glucose transporter but not in glucokinase gene expression. J Clin Invest 1995, 96(5):2489-2495.
-
(1995)
J Clin Invest
, vol.96
, Issue.5
, pp. 2489-2495
-
-
De Vos, A.1
Heimberg, H.2
Quartier, E.3
Huypens, P.4
Bouwens, L.5
Pipeleers, D.6
-
161
-
-
77955584690
-
K(ATP) channelopathies in the pancreas
-
Remedi MS, Koster JC K(ATP) channelopathies in the pancreas. Pflugers Arch 2010, 460(2):307-320.
-
(2010)
Pflugers Arch
, vol.460
, Issue.2
, pp. 307-320
-
-
Remedi, M.S.1
Koster, J.C.2
-
162
-
-
0035960122
-
Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young
-
Fajans SS, Bell GI, Polonsky KS Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young. N Engl J Med 2001, 345(13):971-980.
-
(2001)
N Engl J Med
, vol.345
, Issue.13
, pp. 971-980
-
-
Fajans, S.S.1
Bell, G.I.2
Polonsky, K.S.3
-
163
-
-
33746778878
-
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus
-
Babenko AP, Polak M, Cave H, Busiah K, Czernichow P, Scharfmann R, et al. Activating mutations in the ABCC8 gene in neonatal diabetes mellitus. N Engl J Med 2006, 355(5):456.
-
(2006)
N Engl J Med
, vol.355
, Issue.5
, pp. 456
-
-
Babenko, A.P.1
Polak, M.2
Cave, H.3
Busiah, K.4
Czernichow, P.5
Scharfmann, R.6
-
164
-
-
4644309915
-
Kir6.2 mutations are a common cause of permanent neonatal diabetes in a large cohort of French patients
-
Vaxillaire M, Populaire C, Busiah K, Cave H, Gloyn AL, Hattersley AT, et al. Kir6.2 mutations are a common cause of permanent neonatal diabetes in a large cohort of French patients. Diabetes 2004, 53(10):2719-2722.
-
(2004)
Diabetes
, vol.53
, Issue.10
, pp. 2719-2722
-
-
Vaxillaire, M.1
Populaire, C.2
Busiah, K.3
Cave, H.4
Gloyn, A.L.5
Hattersley, A.T.6
-
165
-
-
33746686369
-
Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations
-
Pearson ER, Flechtner I, Njolstad PR, Malecki MT, Flanagan SE, Larkin B, et al. Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations. N Engl J Med 2006, 355(5):467.
-
(2006)
N Engl J Med
, vol.355
, Issue.5
, pp. 467
-
-
Pearson, E.R.1
Flechtner, I.2
Njolstad, P.R.3
Malecki, M.T.4
Flanagan, S.E.5
Larkin, B.6
-
166
-
-
33847617011
-
Mechanisms of action of glucagon-like peptide 1 in the pancreas
-
Doyle ME, Egan JM Mechanisms of action of glucagon-like peptide 1 in the pancreas. Pharmacol Ther 2007, 113(3):546-593.
-
(2007)
Pharmacol Ther
, vol.113
, Issue.3
, pp. 546-593
-
-
Doyle, M.E.1
Egan, J.M.2
-
167
-
-
69849093583
-
The contribution of incretin hormones to the pathogenesis of type 2 diabetes
-
Meier JJ The contribution of incretin hormones to the pathogenesis of type 2 diabetes. Best Pract Res Clin Endocrinol Metab 2009, 23(4):433-441.
-
(2009)
Best Pract Res Clin Endocrinol Metab
, vol.23
, Issue.4
, pp. 433-441
-
-
Meier, J.J.1
-
168
-
-
68049137605
-
Kir6.2 variant E23K increases ATP-sensitive K+ channel activity and is associated with impaired insulin release and enhanced insulin sensitivity in adults with normal glucose tolerance
-
Villareal DT, Koster JC, Robertson H, Akrouh A, Miyake K, Bell GI, et al. Kir6.2 variant E23K increases ATP-sensitive K+ channel activity and is associated with impaired insulin release and enhanced insulin sensitivity in adults with normal glucose tolerance. Diabetes 2009, 58(8):1869-1878.
-
(2009)
Diabetes
, vol.58
, Issue.8
, pp. 1869-1878
-
-
Villareal, D.T.1
Koster, J.C.2
Robertson, H.3
Akrouh, A.4
Miyake, K.5
Bell, G.I.6
-
169
-
-
0035461345
-
Functional significance of the UCSNP-43 polymorphism in the CAPN10 gene for proinsulin processing and insulin secretion in nondiabetic Germans
-
Stumvoll M, Fritsche A, Madaus A, Stefan N, Weisser M, Machicao F, et al. Functional significance of the UCSNP-43 polymorphism in the CAPN10 gene for proinsulin processing and insulin secretion in nondiabetic Germans. Diabetes 2001, 50(9):2161-2163.
-
(2001)
Diabetes
, vol.50
, Issue.9
, pp. 2161-2163
-
-
Stumvoll, M.1
Fritsche, A.2
Madaus, A.3
Stefan, N.4
Weisser, M.5
Machicao, F.6
-
170
-
-
11244322076
-
Evidence that an isoform of calpain-10 is a regulator of exocytosis in pancreatic beta-cells
-
Marshall C, Hitman GA, Partridge CJ, Clark A, Ma H, Shearer TR, et al. Evidence that an isoform of calpain-10 is a regulator of exocytosis in pancreatic beta-cells. Mol Endocrinol 2005, 19(1):213-224.
-
(2005)
Mol Endocrinol
, vol.19
, Issue.1
, pp. 213-224
-
-
Marshall, C.1
Hitman, G.A.2
Partridge, C.J.3
Clark, A.4
Ma, H.5
Shearer, T.R.6
-
171
-
-
33845409374
-
Calpain facilitates actin reorganization during glucose-stimulated insulin secretion
-
Turner MD, Fulcher FK, Jones CV, Smith BT, Aganna E, Partridge CJ, et al. Calpain facilitates actin reorganization during glucose-stimulated insulin secretion. Biochem Biophys Res Commun 2007, 352(3):650-655.
-
(2007)
Biochem Biophys Res Commun
, vol.352
, Issue.3
, pp. 650-655
-
-
Turner, M.D.1
Fulcher, F.K.2
Jones, C.V.3
Smith, B.T.4
Aganna, E.5
Partridge, C.J.6
-
172
-
-
67349190497
-
A common genetic variant in WFS1 determines impaired glucagon-like peptide-1-induced insulin secretion
-
Schafer SA, Mussig K, Staiger H, Machicao F, Stefan N, Gallwitz B, et al. A common genetic variant in WFS1 determines impaired glucagon-like peptide-1-induced insulin secretion. Diabetologia 2009, 52(6):1075-1082.
-
(2009)
Diabetologia
, vol.52
, Issue.6
, pp. 1075-1082
-
-
Schafer, S.A.1
Mussig, K.2
Staiger, H.3
Machicao, F.4
Stefan, N.5
Gallwitz, B.6
-
173
-
-
49249110747
-
Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation
-
Sparso T, Andersen G, Albrechtsen A, Jorgensen T, Borch-Johnsen K, Sandbaek A, et al. Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation. Diabetologia 2008, 51(9):1646-1652.
-
(2008)
Diabetologia
, vol.51
, Issue.9
, pp. 1646-1652
-
-
Sparso, T.1
Andersen, G.2
Albrechtsen, A.3
Jorgensen, T.4
Borch-Johnsen, K.5
Sandbaek, A.6
-
174
-
-
35848942800
-
Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms
-
Schafer SA, Tschritter O, Machicao F, Thamer C, Stefan N, Gallwitz B, et al. Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms. Diabetologia 2007, 50(12):2443-2450.
-
(2007)
Diabetologia
, vol.50
, Issue.12
, pp. 2443-2450
-
-
Schafer, S.A.1
Tschritter, O.2
Machicao, F.3
Thamer, C.4
Stefan, N.5
Gallwitz, B.6
-
175
-
-
41149178492
-
Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion
-
Kirchhoff K, Machicao F, Haupt A, Schafer SA, Tschritter O, Staiger H, et al. Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion. Diabetologia 2008, 51(4):597-601.
-
(2008)
Diabetologia
, vol.51
, Issue.4
, pp. 597-601
-
-
Kirchhoff, K.1
Machicao, F.2
Haupt, A.3
Schafer, S.A.4
Tschritter, O.5
Staiger, H.6
-
176
-
-
38149035064
-
Association of TCF7L2 gene polymorphisms with reduced acute insulin response in Hispanic Americans
-
Palmer ND, Lehtinen AB, Langefeld CD, Campbell JK, Haffner SM, Norris JM, et al. Association of TCF7L2 gene polymorphisms with reduced acute insulin response in Hispanic Americans. J Clin Endocrinol Metab 2008, 93(1):304-309.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, Issue.1
, pp. 304-309
-
-
Palmer, N.D.1
Lehtinen, A.B.2
Langefeld, C.D.3
Campbell, J.K.4
Haffner, S.M.5
Norris, J.M.6
-
177
-
-
33845542020
-
Polymorphism in the transcription factor 7-like 2 (TCF7L2) gene is associated with reduced insulin secretion in nondiabetic women
-
Munoz J, Lok KH, Gower BA, Fernandez JR, Hunter GR, Lara-Castro C, et al. Polymorphism in the transcription factor 7-like 2 (TCF7L2) gene is associated with reduced insulin secretion in nondiabetic women. Diabetes 2006, 55(12):3630-3634.
-
(2006)
Diabetes
, vol.55
, Issue.12
, pp. 3630-3634
-
-
Munoz, J.1
Lok, K.H.2
Gower, B.A.3
Fernandez, J.R.4
Hunter, G.R.5
Lara-Castro, C.6
-
178
-
-
33750892139
-
Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals
-
Saxena R, Gianniny L, Burtt NP, Lyssenko V, Giuducci C, Sjogren M, et al. Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals. Diabetes 2006, 55(10):2890-2895.
-
(2006)
Diabetes
, vol.55
, Issue.10
, pp. 2890-2895
-
-
Saxena, R.1
Gianniny, L.2
Burtt, N.P.3
Lyssenko, V.4
Giuducci, C.5
Sjogren, M.6
-
179
-
-
41849117959
-
The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients - the EUGENE2 study
-
Boesgaard TW, Zilinskaite J, Vanttinen M, Laakso M, Jansson PA, Hammarstedt A, et al. The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients - the EUGENE2 study. Diabetologia 2008, 51(5):816-820.
-
(2008)
Diabetologia
, vol.51
, Issue.5
, pp. 816-820
-
-
Boesgaard, T.W.1
Zilinskaite, J.2
Vanttinen, M.3
Laakso, M.4
Jansson, P.A.5
Hammarstedt, A.6
-
180
-
-
42449159284
-
Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study
-
Palmer ND, Goodarzi MO, Langefeld CD, Ziegler J, Norris JM, Haffner SM, et al. Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study. Diabetes 2008, 57(4):1093-1100.
-
(2008)
Diabetes
, vol.57
, Issue.4
, pp. 1093-1100
-
-
Palmer, N.D.1
Goodarzi, M.O.2
Langefeld, C.D.3
Ziegler, J.4
Norris, J.M.5
Haffner, S.M.6
-
181
-
-
38849129636
-
Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function
-
Staiger H, Machicao F, Stefan N, Tschritter O, Thamer C, Kantartzis K, et al. Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function. PLoS ONE 2007, 2(9):e832.
-
(2007)
PLoS ONE
, vol.2
, Issue.9
-
-
Staiger, H.1
Machicao, F.2
Stefan, N.3
Tschritter, O.4
Thamer, C.5
Kantartzis, K.6
-
182
-
-
40749087319
-
A candidate type 2 diabetes polymorphism near the HHEX locus affects acute glucose-stimulated insulin release in European populations: results from the EUGENE2 study
-
Staiger H, Stancakova A, Zilinskaite J, Vanttinen M, Hansen T, Marini MA, et al. A candidate type 2 diabetes polymorphism near the HHEX locus affects acute glucose-stimulated insulin release in European populations: results from the EUGENE2 study. Diabetes 2008, 57(2):514-517.
-
(2008)
Diabetes
, vol.57
, Issue.2
, pp. 514-517
-
-
Staiger, H.1
Stancakova, A.2
Zilinskaite, J.3
Vanttinen, M.4
Hansen, T.5
Marini, M.A.6
-
183
-
-
50049128467
-
Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention program
-
Moore AF, Jablonski KA, McAteer JB, Saxena R, Pollin TI, Franks PW, et al. Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention program. Diabetes 2008, 57(9):2503-2510.
-
(2008)
Diabetes
, vol.57
, Issue.9
, pp. 2503-2510
-
-
Moore, A.F.1
Jablonski, K.A.2
McAteer, J.B.3
Saxena, R.4
Pollin, T.I.5
Franks, P.W.6
-
184
-
-
35449001954
-
Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function
-
Pascoe L, Tura A, Patel SK, Ibrahim IM, Ferrannini E, Zeggini E, et al. Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function. Diabetes 2007, 56(12):3101-3104.
-
(2007)
Diabetes
, vol.56
, Issue.12
, pp. 3101-3104
-
-
Pascoe, L.1
Tura, A.2
Patel, S.K.3
Ibrahim, I.M.4
Ferrannini, E.5
Zeggini, E.6
-
185
-
-
43249095915
-
Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance
-
Stancakova A, Pihlajamaki J, Kuusisto J, Stefan N, Fritsche A, Haring H, et al. Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance. J Clin Endocrinol Metab 2008, 93(5):1924-1930.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, Issue.5
, pp. 1924-1930
-
-
Stancakova, A.1
Pihlajamaki, J.2
Kuusisto, J.3
Stefan, N.4
Fritsche, A.5
Haring, H.6
-
186
-
-
49249094275
-
Variants of CDKAL1 and IGF2BP2 affect first-phase insulin secretion during hyperglycaemic clamps
-
Groenewoud MJ, Dekker JM, Fritsche A, Reiling E, Nijpels G, Heine RJ, et al. Variants of CDKAL1 and IGF2BP2 affect first-phase insulin secretion during hyperglycaemic clamps. Diabetologia 2008, 51(9):1659-1663.
-
(2008)
Diabetologia
, vol.51
, Issue.9
, pp. 1659-1663
-
-
Groenewoud, M.J.1
Dekker, J.M.2
Fritsche, A.3
Reiling, E.4
Nijpels, G.5
Heine, R.J.6
-
187
-
-
66649101376
-
Genetic variation in KCNQ1 associates with fasting glucose and beta-cell function: a study of 3,734 subjects comprising three ethnicities living in Singapore
-
Tan JT, Nurbaya S, Gardner D, Ye S, Tai ES, Ng DP Genetic variation in KCNQ1 associates with fasting glucose and beta-cell function: a study of 3,734 subjects comprising three ethnicities living in Singapore. Diabetes 2009, 58(6):1445-1449.
-
(2009)
Diabetes
, vol.58
, Issue.6
, pp. 1445-1449
-
-
Tan, J.T.1
Nurbaya, S.2
Gardner, D.3
Ye, S.4
Tai, E.S.5
Ng, D.P.6
-
188
-
-
0036314298
-
K(IR)6.2 polymorphism predisposes to type 2 diabetes by inducing overactivity of pancreatic beta-cell ATP-sensitive K(+) channels
-
Schwanstecher C, Meyer U, Schwanstecher M K(IR)6.2 polymorphism predisposes to type 2 diabetes by inducing overactivity of pancreatic beta-cell ATP-sensitive K(+) channels. Diabetes 2002, 51(3):875-879.
-
(2002)
Diabetes
, vol.51
, Issue.3
, pp. 875-879
-
-
Schwanstecher, C.1
Meyer, U.2
Schwanstecher, M.3
-
189
-
-
0036724723
-
The prevalent Glu23Lys polymorphism in the potassium inward rectifier 6.2 (KIR6.2) gene is associated with impaired glucagon suppression in response to hyperglycemia
-
Tschritter O, Stumvoll M, Machicao F, Holzwarth M, Weisser M, Maerker E, et al. The prevalent Glu23Lys polymorphism in the potassium inward rectifier 6.2 (KIR6.2) gene is associated with impaired glucagon suppression in response to hyperglycemia. Diabetes 2002, 51(9):2854-2860.
-
(2002)
Diabetes
, vol.51
, Issue.9
, pp. 2854-2860
-
-
Tschritter, O.1
Stumvoll, M.2
Machicao, F.3
Holzwarth, M.4
Weisser, M.5
Maerker, E.6
-
190
-
-
34250307235
-
A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans
-
MacDonald PE, De Marinis YZ, Ramracheya R, Salehi A, Ma X, Johnson PR, et al. A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans. PLoS Biol 2007, 5(6):el43.
-
(2007)
PLoS Biol
, vol.5
, Issue.6
-
-
MacDonald, P.E.1
De Marinis, Y.Z.2
Ramracheya, R.3
Salehi, A.4
Ma, X.5
Johnson, P.R.6
-
191
-
-
38649116056
-
Selective versus total insulin resistance: a pathogenic paradox
-
Brown MS, Goldstein JL Selective versus total insulin resistance: a pathogenic paradox. Cell Metab 2008, 7(2):95-96.
-
(2008)
Cell Metab
, vol.7
, Issue.2
, pp. 95-96
-
-
Brown, M.S.1
Goldstein, J.L.2
-
192
-
-
11144240071
-
Diabetes: outfoxing insulin resistance?
-
Montminy M, Koo SH Diabetes: outfoxing insulin resistance?. Nature 2004, 432(7020):958-959.
-
(2004)
Nature
, vol.432
, Issue.7020
, pp. 958-959
-
-
Montminy, M.1
Koo, S.H.2
-
193
-
-
33644660954
-
Role of the forkhead protein FoxO1 in beta cell compensation to insulin resistance
-
Okamoto H, Hribal ML, Lin HV, Bennett WR, Ward A, Accili D Role of the forkhead protein FoxO1 in beta cell compensation to insulin resistance. J Clin Invest 2006, 116(3):775-782.
-
(2006)
J Clin Invest
, vol.116
, Issue.3
, pp. 775-782
-
-
Okamoto, H.1
Hribal, M.L.2
Lin, H.V.3
Bennett, W.R.4
Ward, A.5
Accili, D.6
-
194
-
-
33745315716
-
Transcription factor FoxO1 mediates glucagon-like peptide-1 effects on pancreatic beta-cell mass
-
Buteau J, Spatz ML, Accili D Transcription factor FoxO1 mediates glucagon-like peptide-1 effects on pancreatic beta-cell mass. Diabetes 2006, 55(5):1190-1196.
-
(2006)
Diabetes
, vol.55
, Issue.5
, pp. 1190-1196
-
-
Buteau, J.1
Spatz, M.L.2
Accili, D.3
-
196
-
-
20144389835
-
Serum- and glucocorticoid-inducible kinase 1 (SGK1) mediates glucocorticoid-induced inhibition of insulin secretion
-
Ullrich S, Berchtold S, Ranta F, Seebohm G, Henke G, Lupescu A, et al. Serum- and glucocorticoid-inducible kinase 1 (SGK1) mediates glucocorticoid-induced inhibition of insulin secretion. Diabetes 2005, 54(4):1090-1099.
-
(2005)
Diabetes
, vol.54
, Issue.4
, pp. 1090-1099
-
-
Ullrich, S.1
Berchtold, S.2
Ranta, F.3
Seebohm, G.4
Henke, G.5
Lupescu, A.6
-
197
-
-
0033912350
-
Characterisation of beta-cell dysfunction of impaired glucose tolerance: evidence for impairment of incretin-induced insulin secretion
-
Fritsche A, Stefan N, Hardt E, Haring H, Stumvoll M Characterisation of beta-cell dysfunction of impaired glucose tolerance: evidence for impairment of incretin-induced insulin secretion. Diabetologia 2000, 43(7):852-858.
-
(2000)
Diabetologia
, vol.43
, Issue.7
, pp. 852-858
-
-
Fritsche, A.1
Stefan, N.2
Hardt, E.3
Haring, H.4
Stumvoll, M.5
-
198
-
-
1342263517
-
Hex homeobox gene-dependent tissue positioning is required for organogénesis of the ventral pancreas
-
Bort R, Martinez-Barbera JP, Beddington RS, Zaret KS Hex homeobox gene-dependent tissue positioning is required for organogénesis of the ventral pancreas. Development 2004, 131(4):797-806.
-
(2004)
Development
, vol.131
, Issue.4
, pp. 797-806
-
-
Bort, R.1
Martinez-Barbera, J.P.2
Beddington, R.S.3
Zaret, K.S.4
-
199
-
-
33751183948
-
In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion
-
Chimienti F, Devergnas S, Pattou F, Schuit F, Garcia-Cuenca R, Vandewalle B, et al. In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion. J Cell Sei 2006, 119(Pt 20):4199-4206.
-
(2006)
J Cell Sei
, vol.119
, Issue.PART 20
, pp. 4199-4206
-
-
Chimienti, F.1
Devergnas, S.2
Pattou, F.3
Schuit, F.4
Garcia-Cuenca, R.5
Vandewalle, B.6
-
200
-
-
0036786193
-
Melatonin inhibits insulin secretion and decreases PKA levels without interfering with glucose metabolism in rat pancreatic islets
-
Picinato MC, Haber EP, Cipolla-Neto J, Curi R, Oliveira Carvalho CR, Carpinelli AR Melatonin inhibits insulin secretion and decreases PKA levels without interfering with glucose metabolism in rat pancreatic islets. J Pineal Res 2002, 33(3):156-160.
-
(2002)
J Pineal Res
, vol.33
, Issue.3
, pp. 156-160
-
-
Picinato, M.C.1
Haber, E.P.2
Cipolla-Neto, J.3
Curi, R.4
Oliveira Carvalho, C.R.5
Carpinelli, A.R.6
-
201
-
-
0036720357
-
Receptor (MT(1)) mediated influence of melatonin on cAMP concentration and insulin secretion of rat insulinoma cells INS-1
-
Peschke E, Muhlbauer E, Musshoff U, Csernus VJ, Chankiewitz E, Peschke D Receptor (MT(1)) mediated influence of melatonin on cAMP concentration and insulin secretion of rat insulinoma cells INS-1. J Pineal Res 2002, 33(2):63-71.
-
(2002)
J Pineal Res
, vol.33
, Issue.2
, pp. 63-71
-
-
Peschke, E.1
Muhlbauer, E.2
Musshoff, U.3
Csernus, V.J.4
Chankiewitz, E.5
Peschke, D.6
-
202
-
-
0037077043
-
Identification and functional characterization of melatonin Mel la receptors in pancreatic beta cells: potential role in incretin-mediated cell function by sensitization of cAMP signaling
-
Kemp DM, Ubeda M, Habener JF Identification and functional characterization of melatonin Mel la receptors in pancreatic beta cells: potential role in incretin-mediated cell function by sensitization of cAMP signaling. Mol Cell Endocrinol 2002, 191(2):157-166.
-
(2002)
Mol Cell Endocrinol
, vol.191
, Issue.2
, pp. 157-166
-
-
Kemp, D.M.1
Ubeda, M.2
Habener, J.F.3
-
203
-
-
36849034462
-
Melatonin, endocrine pancreas and diabetes
-
Peschke E Melatonin, endocrine pancreas and diabetes. J Pineal Res 2008, 44(1):26-40.
-
(2008)
J Pineal Res
, vol.44
, Issue.1
, pp. 26-40
-
-
Peschke, E.1
-
204
-
-
33645098511
-
Parallel signaling pathways of melatonin in the pancreatic beta-cell
-
Peschke E, Bach AG, Muhlbauer E Parallel signaling pathways of melatonin in the pancreatic beta-cell. J Pineal Res 2006, 40(2):184-191.
-
(2006)
J Pineal Res
, vol.40
, Issue.2
, pp. 184-191
-
-
Peschke, E.1
Bach, A.G.2
Muhlbauer, E.3
-
205
-
-
40849142345
-
Function and expression of melatonin receptors on human pancreatic islets
-
Ramracheya RD, Muller DS, Squires PE, Brereton H, Sugden D, Huang GC, et al. Function and expression of melatonin receptors on human pancreatic islets. J Pineal Res 2008, 44(3):273-279.
-
(2008)
J Pineal Res
, vol.44
, Issue.3
, pp. 273-279
-
-
Ramracheya, R.D.1
Muller, D.S.2
Squires, P.E.3
Brereton, H.4
Sugden, D.5
Huang, G.C.6
-
206
-
-
23044443563
-
Characterization of the role of CaMKI-like kinase (CKLiK) in human granulocyte function
-
Verploegen S, Ulfman L, van Deutekom HW, van Aalst C, Honing H, Lammers JW, et al. Characterization of the role of CaMKI-like kinase (CKLiK) in human granulocyte function. Blood 2005, 106(3):1076-1083.
-
(2005)
Blood
, vol.106
, Issue.3
, pp. 1076-1083
-
-
Verploegen, S.1
Ulfman, L.2
van Deutekom, H.W.3
van Aalst, C.4
Honing, H.5
Lammers, J.W.6
-
207
-
-
0141618356
-
Identification of a gene rearranged by 2p21 aberrations in thyroid adenomas
-
Rippe V, Drieschner N, Meiboom M, Murua EH, Bonk U, Belge G, et al. Identification of a gene rearranged by 2p21 aberrations in thyroid adenomas. Oncogene 2003, 22(38):6111-6114.
-
(2003)
Oncogene
, vol.22
, Issue.38
, pp. 6111-6114
-
-
Rippe, V.1
Drieschner, N.2
Meiboom, M.3
Murua, E.H.4
Bonk, U.5
Belge, G.6
-
208
-
-
34347393853
-
TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population
-
Loos RJ, Franks PW, Francis RW, Barroso I, Gribble FM, Savage DB, et al. TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population. Diabetes 2007, 56(7):1943-1947.
-
(2007)
Diabetes
, vol.56
, Issue.7
, pp. 1943-1947
-
-
Loos, R.J.1
Franks, P.W.2
Francis, R.W.3
Barroso, I.4
Gribble, F.M.5
Savage, D.B.6
-
209
-
-
61449237995
-
TCF7L2 variants are associated with increased proinsulin/insulin ratios but not obesity traits in the Framingham Heart Study
-
Stolerman ES, Manning AK, McAteer JB, Fox CS, Dupuis J, Meigs JB, et al. TCF7L2 variants are associated with increased proinsulin/insulin ratios but not obesity traits in the Framingham Heart Study. Diabetologia 2009, 52(4):614-620.
-
(2009)
Diabetologia
, vol.52
, Issue.4
, pp. 614-620
-
-
Stolerman, E.S.1
Manning, A.K.2
McAteer, J.B.3
Fox, C.S.4
Dupuis, J.5
Meigs, J.B.6
-
210
-
-
64649105053
-
TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells
-
da Silva X, Loder MK, McDonald A, Tarasov AI, Carzaniga R, Kronenberger K, et al. TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells. Diabetes 2009, 58(4):894-905.
-
(2009)
Diabetes
, vol.58
, Issue.4
, pp. 894-905
-
-
da Silva, X.1
Loder, M.K.2
McDonald, A.3
Tarasov, A.I.4
Carzaniga, R.5
Kronenberger, K.6
-
211
-
-
34547702501
-
Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes
-
Lyssenko V, Lupi R, Marchetti P, Del Guerra S, Orho-Melander M, Almgren P, et al. Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes. J Clin Invest 2007, 117(8):2155-2163.
-
(2007)
J Clin Invest
, vol.117
, Issue.8
, pp. 2155-2163
-
-
Lyssenko, V.1
Lupi, R.2
Marchetti, P.3
Del Guerra, S.4
Orho-Melander, M.5
Almgren, P.6
-
212
-
-
67349102328
-
The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men
-
Pilgaard K, Jensen CB, Schou JH, Lyssenko V, Wegner L, Brons C, et al. The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men. Diabetologia 2009, 52(7):1298-1307.
-
(2009)
Diabetologia
, vol.52
, Issue.7
, pp. 1298-1307
-
-
Pilgaard, K.1
Jensen, C.B.2
Schou, J.H.3
Lyssenko, V.4
Wegner, L.5
Brons, C.6
-
213
-
-
77449099615
-
TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action
-
Villareal DT, Robertson H, Bell GI, Patterson BW, Tran H, Wice B, et al. TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action. Diabetes 2010, 59(2):479-485.
-
(2010)
Diabetes
, vol.59
, Issue.2
, pp. 479-485
-
-
Villareal, D.T.1
Robertson, H.2
Bell, G.I.3
Patterson, B.W.4
Tran, H.5
Wice, B.6
-
214
-
-
45249084351
-
TCF7L2 controls insulin gene expression and insulin secretion in mature pancreatic beta-cells
-
Loder MK, da Silva X, McDonald A, Rutter GA TCF7L2 controls insulin gene expression and insulin secretion in mature pancreatic beta-cells. Biochem Soc Trans 2008, 36(Pt 3):357-359.
-
(2008)
Biochem Soc Trans
, vol.36
, Issue.PART 3
, pp. 357-359
-
-
Loder, M.K.1
da Silva, X.2
McDonald, A.3
Rutter, G.A.4
-
215
-
-
12544254474
-
TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta
-
Yi F, Brubaker PL, Jin T TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta. J Biol Chem 2005, 280(2):1457-1464.
-
(2005)
J Biol Chem
, vol.280
, Issue.2
, pp. 1457-1464
-
-
Yi, F.1
Brubaker, P.L.2
Jin, T.3
-
216
-
-
34547516561
-
Wnt signaling regulates pancreatic beta cell proliferation
-
Rulifson IC, Karnik SK, Heiser PW, ten Berge D, Chen H, Gu X, et al. Wnt signaling regulates pancreatic beta cell proliferation. Proc Nati Acad Sei U S A 2007, 104(15):6247-6252.
-
(2007)
Proc Nati Acad Sei U S A
, vol.104
, Issue.15
, pp. 6247-6252
-
-
Rulifson, I.C.1
Karnik, S.K.2
Heiser, P.W.3
ten Berge, D.4
Chen, H.5
Gu, X.6
-
217
-
-
40949141938
-
Transcription factor 7-like 2 regulates beta-cell survival and function in human pancreatic islets
-
Shu L, Sauter NS, Schulthess FT, Matveyenko AV, Oberholzer J, Maedler K Transcription factor 7-like 2 regulates beta-cell survival and function in human pancreatic islets. Diabetes 2008, 57(3):645-653.
-
(2008)
Diabetes
, vol.57
, Issue.3
, pp. 645-653
-
-
Shu, L.1
Sauter, N.S.2
Schulthess, F.T.3
Matveyenko, A.V.4
Oberholzer, J.5
Maedler, K.6
-
218
-
-
67249096093
-
Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP-and GLP-1 receptors and impaired beta-cell function
-
Shu L, Matveyenko AV, Kerr-Conte J, Cho JH, McIntosh CH, Maedler K Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP-and GLP-1 receptors and impaired beta-cell function. Hum Mol Genet 2009, 18(13):2388-2399.
-
(2009)
Hum Mol Genet
, vol.18
, Issue.13
, pp. 2388-2399
-
-
Shu, L.1
Matveyenko, A.V.2
Kerr-Conte, J.3
Cho, J.H.4
McIntosh, C.H.5
Maedler, K.6
-
219
-
-
0035283066
-
WFS1 (Wolfram syndrome 1) gene product: predominant subcellular localization to endoplasmic reticulum in cultured cells and neuronal expression in rat brain
-
Takeda K, Inoue H, Tanizawa Y, Matsuzaki Y, Oba J, Watanabe Y, et al. WFS1 (Wolfram syndrome 1) gene product: predominant subcellular localization to endoplasmic reticulum in cultured cells and neuronal expression in rat brain. Hum Mol Genet 2001, 10(5):477-484.
-
(2001)
Hum Mol Genet
, vol.10
, Issue.5
, pp. 477-484
-
-
Takeda, K.1
Inoue, H.2
Tanizawa, Y.3
Matsuzaki, Y.4
Oba, J.5
Watanabe, Y.6
-
220
-
-
0030826078
-
Wolfram (DIDMOAD) syndrome
-
Barrett TG, Bundey SE Wolfram (DIDMOAD) syndrome. J Med Genet 1997, 34(10):838-841.
-
(1997)
J Med Genet
, vol.34
, Issue.10
, pp. 838-841
-
-
Barrett, T.G.1
Bundey, S.E.2
-
221
-
-
2942731683
-
Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion
-
Ishihara H, Takeda S, Tamura A, Takahashi R, Yamaguchi S, Takei D, et al. Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion. Hum Mol Genet 2004, 13(11):1159-1170.
-
(2004)
Hum Mol Genet
, vol.13
, Issue.11
, pp. 1159-1170
-
-
Ishihara, H.1
Takeda, S.2
Tamura, A.3
Takahashi, R.4
Yamaguchi, S.5
Takei, D.6
-
222
-
-
27744523525
-
Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis
-
Riggs AC, Bernal-Mizrachi E, Ohsugi M, Wasson J, Fatrai S, Welling C, et al. Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis. Diabetologia 2005, 48(11):2313-2321.
-
(2005)
Diabetologia
, vol.48
, Issue.11
, pp. 2313-2321
-
-
Riggs, A.C.1
Bernal-Mizrachi, E.2
Ohsugi, M.3
Wasson, J.4
Fatrai, S.5
Welling, C.6
-
223
-
-
28244435870
-
WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic beta-cells
-
Fonseca SG, Fukuma M, Lipson KL, Nguyen LX, Allen JR, Oka Y, et al. WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic beta-cells. J Biol Chem 2005, 280(47):39609-39615.
-
(2005)
J Biol Chem
, vol.280
, Issue.47
, pp. 39609-39615
-
-
Fonseca, S.G.1
Fukuma, M.2
Lipson, K.L.3
Nguyen, L.X.4
Allen, J.R.5
Oka, Y.6
-
224
-
-
0035313235
-
Molecular biology and the prolonged QT syndromes
-
Towbin JA, Vatta M Molecular biology and the prolonged QT syndromes. Am J Med 2001, 110(5):385-398.
-
(2001)
Am J Med
, vol.110
, Issue.5
, pp. 385-398
-
-
Towbin, J.A.1
Vatta, M.2
-
225
-
-
29144482537
-
KCNQl-dependent transport in renal and gastrointestinal epithelia
-
Vallon V, Grahammer F, Volkl H, Sandu CD, Richter K, Rexhepaj R, et al. KCNQl-dependent transport in renal and gastrointestinal epithelia. Proc Nati Acad Sei USA 2005, 102(49):17864-17869.
-
(2005)
Proc Nati Acad Sei USA
, vol.102
, Issue.49
, pp. 17864-17869
-
-
Vallon, V.1
Grahammer, F.2
Volkl, H.3
Sandu, C.D.4
Richter, K.5
Rexhepaj, R.6
-
226
-
-
67649427368
-
Whole-grain consumption and transcription factor-7-like 2 (TCF7L2) rs7903146: gene-diet interaction in modulating type 2 diabetes risk
-
Fisher E, Boeing H, Fritsche A, Doering F, Joost HG, Schulze MB Whole-grain consumption and transcription factor-7-like 2 (TCF7L2) rs7903146: gene-diet interaction in modulating type 2 diabetes risk. Br J Nutr 2009, 101(4):478-481.
-
(2009)
Br J Nutr
, vol.101
, Issue.4
, pp. 478-481
-
-
Fisher, E.1
Boeing, H.2
Fritsche, A.3
Doering, F.4
Joost, H.G.5
Schulze, M.B.6
-
227
-
-
77649167599
-
Interactions between genetic factors that predict diabetes and dietary factors that ultimately impact on risk of diabetes
-
Qi L, Liang J Interactions between genetic factors that predict diabetes and dietary factors that ultimately impact on risk of diabetes. Curr Opin Lipidol 2010, 21(1):31-37.
-
(2010)
Curr Opin Lipidol
, vol.21
, Issue.1
, pp. 31-37
-
-
Qi, L.1
Liang, J.2
-
228
-
-
77950344135
-
Gene Variants of TCF7L2 Influence Weight Loss and Body Composition During Lifestyle Intervention in a Population at Risk for Type 2 Diabetes
-
Haupt A, Thamer C, Heni M, Ketterer C, Machann J, Schick F, et al. Gene Variants of TCF7L2 Influence Weight Loss and Body Composition During Lifestyle Intervention in a Population at Risk for Type 2 Diabetes. Diabetes 2010, 59(3):747-750.
-
(2010)
Diabetes
, vol.59
, Issue.3
, pp. 747-750
-
-
Haupt, A.1
Thamer, C.2
Heni, M.3
Ketterer, C.4
Machann, J.5
Schick, F.6
-
229
-
-
39049100084
-
Testing of diabetes-associated WFS1 polymorphisms in the Diabetes Prevention Program
-
Florez JC, Jablonski KA, McAteer J, Sandhu MS, Wareham NJ, Barroso I, et al. Testing of diabetes-associated WFS1 polymorphisms in the Diabetes Prevention Program. Diabetologia 2008, 51(3):451-457.
-
(2008)
Diabetologia
, vol.51
, Issue.3
, pp. 451-457
-
-
Florez, J.C.1
Jablonski, K.A.2
McAteer, J.3
Sandhu, M.S.4
Wareham, N.J.5
Barroso, I.6
-
230
-
-
66649093212
-
Previously associated type 2 diabetes variants may interact with physical activity to modify the risk of impaired glucose regulation and type 2 diabetes: a study of 16,003 Swedish adults
-
Brito EC, Lyssenko V, Renstrom F, Berglund G, Nilsson PM, Groop L, et al. Previously associated type 2 diabetes variants may interact with physical activity to modify the risk of impaired glucose regulation and type 2 diabetes: a study of 16,003 Swedish adults. Diabetes 2009, 58(6):1411-1418.
-
(2009)
Diabetes
, vol.58
, Issue.6
, pp. 1411-1418
-
-
Brito, E.C.1
Lyssenko, V.2
Renstrom, F.3
Berglund, G.4
Nilsson, P.M.5
Groop, L.6
-
231
-
-
34547585382
-
Variation in TCF7L2 influences therapeutic response to sulfonylureas: a GoDARTs study
-
Pearson ER, Donnelly LA, Kimber C, Whitley A, Doney AS, McCarthy MI, et al. Variation in TCF7L2 influences therapeutic response to sulfonylureas: a GoDARTs study. Diabetes 2007, 56(8):2178-2182.
-
(2007)
Diabetes
, vol.56
, Issue.8
, pp. 2178-2182
-
-
Pearson, E.R.1
Donnelly, L.A.2
Kimber, C.3
Whitley, A.4
Doney, A.S.5
McCarthy, M.I.6
-
232
-
-
33748773883
-
Predictive genetic testing for type 2 diabetes
-
Janssens AC, Gwinn M, Valdez R, Narayan KM, Khoury MJ Predictive genetic testing for type 2 diabetes. BMJ 2006, 333(7567):509-510.
-
(2006)
BMJ
, vol.333
, Issue.7567
, pp. 509-510
-
-
Janssens, A.C.1
Gwinn, M.2
Valdez, R.3
Narayan, K.M.4
Khoury, M.J.5
-
233
-
-
34548790660
-
The importance of TCF7L2
-
Weedon MN The importance of TCF7L2. Diabet Med 2007, 24(10):1062-1066.
-
(2007)
Diabet Med
, vol.24
, Issue.10
, pp. 1062-1066
-
-
Weedon, M.N.1
-
234
-
-
1542314297
-
Revisiting the clinical validity of multiplex genetic testing in complex diseases
-
Janssens AC, Pardo MC, Steyerberg EW, van Duijn CM Revisiting the clinical validity of multiplex genetic testing in complex diseases. Am J Hum Genet 2004, 74(3):585-588.
-
(2004)
Am J Hum Genet
, vol.74
, Issue.3
, pp. 585-588
-
-
Janssens, A.C.1
Pardo, M.C.2
Steyerberg, E.W.3
van Duijn, C.M.4
-
235
-
-
33750876203
-
Combining information from common type 2 diabetes risk polymorphisms improves disease prediction
-
Weedon MN, McCarthy MI, Hitman G, Walker M, Groves CJ, Zeggini E, et al. Combining information from common type 2 diabetes risk polymorphisms improves disease prediction. PLoS Med 2006, 3(10):e374.
-
(2006)
PLoS Med
, vol.3
, Issue.10
-
-
Weedon, M.N.1
McCarthy, M.I.2
Hitman, G.3
Walker, M.4
Groves, C.J.5
Zeggini, E.6
-
236
-
-
47749124258
-
Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value
-
Cauchi S, Meyre D, Durand E, Proenca C, Marre M, Hadjadj S, et al. Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value. PLoS ONE 2008, 3(5):e2031.
-
(2008)
PLoS ONE
, vol.3
, Issue.5
-
-
Cauchi, S.1
Meyre, D.2
Durand, E.3
Proenca, C.4
Marre, M.5
Hadjadj, S.6
-
237
-
-
56349096931
-
Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk
-
Lango H, Palmer CN, Morris AD, Zeggini E, Hattersley AT, McCarthy MI, et al. Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk. Diabetes 2008, 57(11):3129-3135.
-
(2008)
Diabetes
, vol.57
, Issue.11
, pp. 3129-3135
-
-
Lango, H.1
Palmer, C.N.2
Morris, A.D.3
Zeggini, E.4
Hattersley, A.T.5
McCarthy, M.I.6
-
238
-
-
70449381518
-
Use of multiple metabolic and genetic markers to improve the prediction of type 2 diabetes: the EPIC-Potsdam Study
-
Schulze MB, Weikert C, Pischon T, Bergmann MM, Al Hasani H, Schleicher E, et al. Use of multiple metabolic and genetic markers to improve the prediction of type 2 diabetes: the EPIC-Potsdam Study. Diabetes Care 2009, 32(11):2116-2119.
-
(2009)
Diabetes Care
, vol.32
, Issue.11
, pp. 2116-2119
-
-
Schulze, M.B.1
Weikert, C.2
Pischon, T.3
Bergmann, M.M.4
Al Hasani, H.5
Schleicher, E.6
-
239
-
-
67349169201
-
Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction
-
Sparso T, Grarup N, Andreasen C, Albrechtsen A, Holmkvist J, Andersen G, et al. Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction. Diabetologia 2009, 52(7):1308-1314.
-
(2009)
Diabetologia
, vol.52
, Issue.7
, pp. 1308-1314
-
-
Sparso, T.1
Grarup, N.2
Andreasen, C.3
Albrechtsen, A.4
Holmkvist, J.5
Andersen, G.6
-
240
-
-
27544432314
-
How many genes underlie the occurrence of common complex diseases in the population?
-
Yang Q, Khoury MJ, Friedman J, Little J, Flanders WD How many genes underlie the occurrence of common complex diseases in the population?. Int J Epidemiol 2005, 34(5):1129-1137.
-
(2005)
Int J Epidemiol
, vol.34
, Issue.5
, pp. 1129-1137
-
-
Yang, Q.1
Khoury, M.J.2
Friedman, J.3
Little, J.4
Flanders, W.D.5
|