-
1
-
-
0242524453
-
The inherited basis of diabetes mellitus: implications for the genetic analysis of complex traits
-
JC Florez J Hirschhorn D Altshuler The inherited basis of diabetes mellitus: implications for the genetic analysis of complex traits Annu Rev Genomics Hum Genet 4 2003 257 291
-
(2003)
Annu Rev Genomics Hum Genet
, vol.4
, pp. 257-291
-
-
Florez, JC1
Hirschhorn, J2
Altshuler, D3
-
2
-
-
33847176604
-
A genome-wide association study identifies novel risk loci for type 2 diabetes
-
R Sladek G Rocheleau J Rung C Dina L Shen D Serre P Boutin D Vincent A Belisle S Hadjadj B Balkau B Heude G Charpentier TJ Hudson A Montpetit AV Pshezhetsky M Prentki BI Posner DJ Balding D Meyre C Polychronakos P Froguel A genome-wide association study identifies novel risk loci for type 2 diabetes Nature 445 2007 881 885
-
(2007)
Nature
, vol.445
, pp. 881-885
-
-
Sladek, R1
Rocheleau, G2
Rung, J3
Dina, C4
Shen, L5
Serre, D6
Boutin, P7
Vincent, D8
Belisle, A9
Hadjadj, S10
Balkau, B11
Heude, B12
Charpentier, G13
Hudson, TJ14
Montpetit, A15
Pshezhetsky, AV16
Prentki, M17
Posner, BI18
Balding, DJ19
Meyre, D20
Polychronakos, C21
Froguel, P22
more..
-
3
-
-
34249895023
-
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
-
E Zeggini MN Weedon CM Lindgren TM Frayling KS Elliott H Lango NJ Timpson JR Perry NW Rayner RM Freathy JC Barrett B Shields AP Morris S Ellard CJ Groves LW Harries JL Marchini KR Owen B Knight LR Cardon M Walker GA Hitman AD Morris AS Doney Wellcome Trust Case Control Consortium (WTCCC) MI McCarthy AT Hattersley Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes Science [Erratum (2007) 317:1035-1036] 316 2007 1336 1341
-
(2007)
Science [Erratum (2007) 317:1035-1036]
, vol.316
, pp. 1336-1341
-
-
Zeggini, E1
Weedon, MN2
Lindgren, CM3
Frayling, TM4
Elliott, KS5
Lango, H6
Timpson, NJ7
Perry, JR8
Rayner, NW9
Freathy, RM10
Barrett, JC11
Shields, B12
Morris, AP13
Ellard, S14
Groves, CJ15
Harries, LW16
Marchini, JL17
Owen, KR18
Knight, B19
Cardon, LR20
Walker, M21
Hitman, GA22
Morris, AD23
Doney, AS24
Wellcome Trust Case Control Consortium (WTCCC)25
McCarthy, MI26
Hattersley, AT27
more..
-
4
-
-
34249828965
-
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes
-
V Steinthorsdottir G Thorleifsson I Reynisdottir R Benediktsson T Jonsdottir GB Walters U Styrkarsdottir S Gretarsdottir V Emilsson S Ghosh A Baker S Snorradottir H Bjarnason MC Ng T Hansen Y Bagger RL Wilensky MP Reilly A Adeyemo Y Chen J Zhou V Gudnason G Chen H Huang K Lashley A Doumatey WY So RC Ma G Andersen K Borch-Johnsen T Jorgensen JV van Vliet-Ostaptchouk MH Hofker C Wijmenga C Christiansen DJ Rader C Rotimi M Gurney JC Chan O Pedersen G Sigurdsson JR Gulcher U Thorsteinsdottir A Kong K Stefansson A variant in CDKAL1 influences insulin response and risk of type 2 diabetes Nat Genet 39 2007 770 775
-
(2007)
Nat Genet
, vol.39
, pp. 770-775
-
-
Steinthorsdottir, V1
Thorleifsson, G2
Reynisdottir, I3
Benediktsson, R4
Jonsdottir, T5
Walters, GB6
Styrkarsdottir, U7
Gretarsdottir, S8
Emilsson, V9
Ghosh, S10
Baker, A11
Snorradottir, S12
Bjarnason, H13
Ng, MC14
Hansen, T15
Bagger, Y16
Wilensky, RL17
Reilly, MP18
Adeyemo, A19
Chen, Y20
Zhou, J21
Gudnason, V22
Chen, G23
Huang, H24
Lashley, K25
Doumatey, A26
So, WY27
Ma, RC28
Andersen, G29
Borch-Johnsen, K30
Jorgensen, T31
van Vliet-Ostaptchouk, JV32
Hofker, MH33
Wijmenga, C34
Christiansen, C35
Rader, DJ36
Rotimi, C37
Gurney, M38
Chan, JC39
Pedersen, O40
Sigurdsson, G41
Gulcher, JR42
Thorsteinsdottir, U43
Kong, A44
Stefansson, K45
more..
-
5
-
-
34249888775
-
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
-
Diabetes Genetics Initiative of Broad Institute of Harvard and MIT Lund University Novartis Institutes of BioMedical Research R Saxena BF Voight V Lyssenko NP Burtt PI de Bakker H Chen JJ Roix S Kathiresan JN Hirschhorn MJ Daly TE Hughes L Groop D Altshuler P Almgren JC Florez J Meyer K Ardlie K Bengtsson Bostrom B Isomaa G Lettre U Lindblad HN Lyon O Melander C Newton-Cheh P Nilsson M Orho-Melander L Rastam EK Speliotes MR Taskinen T Tuomi C Guiducci A Berglund J Carlson L Gianniny R Hackett L Hall J Holmkvist E Laurila M Sjogren M Sterner A Surti M Svensson M Svensson R Tewhey B Blumenstiel M Parkin M Defelice R Barry W Brodeur J Camarata N Chia M Fava J Gibbons B Handsaker C Healy K Nguyen C Gates C Sougnez D Gage M Nizzari SB Gabriel GW Chirn Q Ma H Parikh D Richardson D Ricke S Purcell Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels Science 316 2007 1331 1336
-
(2007)
Science
, vol.316
, pp. 1331-1336
-
-
Diabetes Genetics Initiative of Broad Institute of Harvard and MIT1
Lund University2
Novartis Institutes of BioMedical Research3
Saxena, R4
Voight, BF5
Lyssenko, V6
Burtt, NP7
de Bakker, PI8
Chen, H9
Roix, JJ10
Kathiresan, S11
Hirschhorn, JN12
Daly, MJ13
Hughes, TE14
Groop, L15
Altshuler, D16
Almgren, P17
Florez, JC18
Meyer, J19
Ardlie, K20
Bengtsson Bostrom, K21
Isomaa, B22
Lettre, G23
Lindblad, U24
Lyon, HN25
Melander, O26
Newton-Cheh, C27
Nilsson, P28
Orho-Melander, M29
Rastam, L30
Speliotes, EK31
Taskinen, MR32
Tuomi, T33
Guiducci, C34
Berglund, A35
Carlson, J36
Gianniny, L37
Hackett, R38
Hall, L39
Holmkvist, J40
Laurila, E41
Sjogren, M42
Sterner, M43
Surti, A44
Svensson, M45
Svensson, M46
Tewhey, R47
Blumenstiel, B48
Parkin, M49
Defelice, M50
Barry, R51
Brodeur, W52
Camarata, J53
Chia, N54
Fava, M55
Gibbons, J56
Handsaker, B57
Healy, C58
Nguyen, K59
Gates, C60
Sougnez, C61
Gage, D62
Nizzari, M63
Gabriel, SB64
Chirn, GW65
Ma, Q66
Parikh, H67
Richardson, D68
Ricke, D69
Purcell, S70
more..
-
6
-
-
34249885875
-
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
-
LJ Scott KL Mohlke LL Bonnycastle CJ Willer Y Li WL Duren MR Erdos HM Stringham PS Chines AU Jackson L Prokunina-Olsson CJ Ding AJ Swift N Narisu T Hu R Pruim R Xiao XY Li KN Conneely NL Riebow AG Sprau M Tong PP White KN Hetrick MW Barnhart CW Bark JL Goldstein L Watkins F Xiang J Saramies TA Buchanan RM Watanabe TT Valle L Kinnunen GR Abecasis EW Pugh KF Doheny RN Bergman J Tuomilehto FS Collins M Boehnke A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants Science 316 2007 1341 1345
-
(2007)
Science
, vol.316
, pp. 1341-1345
-
-
Scott, LJ1
Mohlke, KL2
Bonnycastle, LL3
Willer, CJ4
Li, Y5
Duren, WL6
Erdos, MR7
Stringham, HM8
Chines, PS9
Jackson, AU10
Prokunina-Olsson, L11
Ding, CJ12
Swift, AJ13
Narisu, N14
Hu, T15
Pruim, R16
Xiao, R17
Li, XY18
Conneely, KN19
Riebow, NL20
Sprau, AG21
Tong, M22
White, PP23
Hetrick, KN24
Barnhart, MW25
Bark, CW26
Goldstein, JL27
Watkins, L28
Xiang, F29
Saramies, J30
Buchanan, TA31
Watanabe, RM32
Valle, TT33
Kinnunen, L34
Abecasis, GR35
Pugh, EW36
Doheny, KF37
Bergman, RN38
Tuomilehto, J39
Collins, FS40
Boehnke, M41
more..
-
8
-
-
33750014263
-
Extraneuronal roles of cyclin-dependent kinase 5
-
JL Rosales KY Lee Extraneuronal roles of cyclin-dependent kinase 5 Bioessays 28 2006 1023 1034
-
(2006)
Bioessays
, vol.28
, pp. 1023-1034
-
-
Rosales, JL1
Lee, KY2
-
9
-
-
33749389928
-
Inhibition of cyclin-dependent kinase 5 activity protects pancreatic β-cells from glucotoxicity
-
M Ubeda JM Rukstalis JF Habener Inhibition of cyclin-dependent kinase 5 activity protects pancreatic β-cells from glucotoxicity J Biol Chem 281 2006 28858 28864
-
(2006)
J Biol Chem
, vol.281
, pp. 28858-28864
-
-
Ubeda, M1
Rukstalis, JM2
Habener, JF3
-
10
-
-
0031851293
-
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
-
KG Alberti PZ Zimmet Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation Diabet Med 15 1998 539 553
-
(1998)
Diabet Med
, vol.15
, pp. 539-553
-
-
Alberti, KG1
Zimmet, PZ2
-
11
-
-
0018520840
-
Glucose clamp technique: a method for quantifying insulin secretion and resistance
-
RA DeFronzo JD Tobin R Andres Glucose clamp technique: a method for quantifying insulin secretion and resistance Am J Physiol 237 1979 E214 E223
-
(1979)
Am J Physiol
, vol.237
, pp. E214-E223
-
-
DeFronzo, RA1
Tobin, JD2
Andres, R3
-
12
-
-
0031027502
-
Characterization of the MODY3 phenotype. Early-onset diabetes caused by an insulin secretion defect
-
M Lehto T Tuomi MM Mahtani E Widen C Forsblom L Sarelin M Gullström B Isomaa M Lehtovirta A Hyrkkö T Kanninen M Orho S Manley RC Turner T Brettin A Kirby J Thomas G Duyk E Lander MR Taskinen L Groop Characterization of the MODY3 phenotype. Early-onset diabetes caused by an insulin secretion defect J Clin Invest 99 1997 582 591
-
(1997)
J Clin Invest
, vol.99
, pp. 582-591
-
-
Lehto, M1
Tuomi, T2
Mahtani, MM3
Widen, E4
Forsblom, C5
Sarelin, L6
Gullström, M7
Isomaa, B8
Lehtovirta, M9
Hyrkkö, A10
Kanninen, T11
Orho, M12
Manley, S13
Turner, RC14
Brettin, T15
Kirby, A16
Thomas, J17
Duyk, G18
Lander, E19
Taskinen, MR20
Groop, L21
more..
-
13
-
-
0022361971
-
Assessment of insulin sensitivity in vivo
-
RN Bergman DT Finegood M Ader Assessment of insulin sensitivity in vivo Endocr Rev 6 1985 45 86
-
(1985)
Endocr Rev
, vol.6
, pp. 45-86
-
-
Bergman, RN1
Finegood, DT2
Ader, M3
-
14
-
-
0028204065
-
Understanding oral glucose tolerance: comparison of glucose or insulin measurements during the oral glucose tolerance test with specific measurements of insulin resistance and insulin secretion
-
DI Phillips PM Clark CN Hales C Osmond Understanding oral glucose tolerance: comparison of glucose or insulin measurements during the oral glucose tolerance test with specific measurements of insulin resistance and insulin secretion Diabet Med 11 1994 286 292
-
(1994)
Diabet Med
, vol.11
, pp. 286-292
-
-
Phillips, DI1
Clark, PM2
Hales, CN3
Osmond, C4
-
15
-
-
0034650163
-
Evaluation of simple indices of insulin sensitivity and insulin secretion for use in epidemiologic studies
-
RL Hanson RE Pratley C Bogardus KM Narayan JM Roumain G Imperatore A Fagot-Campagna DJ Pettitt PH Bennett WC Knowler Evaluation of simple indices of insulin sensitivity and insulin secretion for use in epidemiologic studies Am J Epidemiol 151 2000 190 198
-
(2000)
Am J Epidemiol
, vol.151
, pp. 190-198
-
-
Hanson, RL1
Pratley, RE2
Bogardus, C3
Narayan, KM4
Roumain, JM5
Imperatore, G6
Fagot-Campagna, A7
Pettitt, DJ8
Bennett, PH9
Knowler, WC10
-
16
-
-
0019810028
-
Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and β-cell glucose sensitivity from the response to intravenous glucose
-
RN Bergman LS Phillips C Cobelli Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and β-cell glucose sensitivity from the response to intravenous glucose J Clin Invest 68 1981 1456 1467
-
(1981)
J Clin Invest
, vol.68
, pp. 1456-1467
-
-
Bergman, RN1
Phillips, LS2
Cobelli, C3
-
17
-
-
34249785394
-
Acute insulin response is an independent predictor of type 2 diabetes mellitus in individuals with both normal fasting and 2-h plasma glucose concentrations
-
JC Bunt J Krakoff E Ortega WC Knowler C Bogardus Acute insulin response is an independent predictor of type 2 diabetes mellitus in individuals with both normal fasting and 2-h plasma glucose concentrations Diabetes Metab Res Rev 23 2007 304 310
-
(2007)
Diabetes Metab Res Rev
, vol.23
, pp. 304-310
-
-
Bunt, JC1
Krakoff, J2
Ortega, E3
Knowler, WC4
Bogardus, C5
-
18
-
-
0025861715
-
Risk factors for developing non-insulin dependent diabetes: a 10 year follow up of men in Uppsala
-
ET Skarfors KI Selinus HO Lithell Risk factors for developing non-insulin dependent diabetes: a 10 year follow up of men in Uppsala BMJ 303 1991 755 760
-
(1991)
BMJ
, vol.303
, pp. 755-760
-
-
Skarfors, ET1
Selinus, KI2
Lithell, HO3
-
20
-
-
27144441483
-
Cdk5-dependent regulation of glucose-stimulated insulin secretion
-
FY Wei K Nagashima T Ohshima Y Saheki YF Lu M Matsushita Y Yamada K Mikoshiba Y Seino H Matsui K Tomizawa Cdk5-dependent regulation of glucose-stimulated insulin secretion Nat Med 11 2005 1104 1108
-
(2005)
Nat Med
, vol.11
, pp. 1104-1108
-
-
Wei, FY1
Nagashima, K2
Ohshima, T3
Saheki, Y4
Lu, YF5
Matsushita, M6
Yamada, Y7
Mikoshiba, K8
Seino, Y9
Matsui, H10
Tomizawa, K11
|