WFS1 (Wolfram syndrome 1) gene product: Predominant subcellular localization to endoplasmic reticulum in cultured cells and neuronal expression in rat brain

Human Molecular Genetics

Volumn 10, Issue 5, 2001, Pages 477-484

  Takeda, Koumei ^a   Inoue, Hiroshi ^a   Tanizawa, Yukio ^a   Matsuzaki, Yumiko ^a   Oba, Jun ^a   Watanabe, Yoshifumi ^a   Shinoda, Koh ^a   Oka, Yoshitomo ^a  

^a YAMAGUCHI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; GENE PRODUCT; GLYCOSIDASE; MEMBRANE PROTEIN; MESSENGER RNA; PROTEIN;

AMYGDALOID NUCLEUS; ANIMAL TISSUE; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; BEHAVIOR; BIOCHEMISTRY; BRAIN CELL; CALCIUM HOMEOSTASIS; CARBOXY TERMINAL SEQUENCE; CELL POPULATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; DEGENERATIVE DISEASE; EMOTION; ENDOCRINE CELL; ENDOPLASMIC RETICULUM; GENE FUNCTION; HIPPOCAMPUS; HUMAN; HUMAN CELL; HYPOTHESIS; IMMUNOFLUORESCENCE; INSULIN DEPENDENT DIABETES MELLITUS; LIMBIC SYSTEM; MEMBRANE TRANSPORT; MITOCHONDRION; MULTIGENE FAMILY; NERVE CELL CULTURE; NONHUMAN; NUCLEOTIDE SEQUENCE; OLFACTORY BULB; OLFACTORY CORTEX; OPTIC NERVE ATROPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; PSYCHIATRY; RAT; REGULATORY MECHANISM; STAINING; WOLFRAM SYNDROME;

ANIMALIA;

EID: 0035283066     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/10.5.477     Document Type: Article

References (29)

1. Wolfram (DIDMOAD) syndrome
2. Neurodegeneration and diabetes: UK nationwide study of Wolfram (DIDMOAD) syndrome
3. Evidence of widespread axonal pathology in Wolfram syndrome
4. Wolfram syndrome: A neuropathological study
5. The Wolfram syndrome: A primary neurodegenerative disorder with lethal potential
6. A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome)
7. Clinical and molecular genetic analysis of 19 Wolfram syndrome kindreds demonstrating a wide spectrum of mutations in WFS1
8. Diabetes insipidus, diabetes mellitus, optic atrophy and deafness (DIDMOAD) caused by mutations in a novel gene (wolframin) coding for a predicted transmembrane protein
9. Wolframin mutations in Spanish families with Wolfram syndrome
10. Wolfram syndrome: A mitochondrial-mediated disorder?
11. Autosomal recessive Wolfram syndrome associated with an 8.5-kb mtDNA single deletion
12. The mitochondrial genome in Wolfram syndrome
13. Calnexin, calreticulin and Bip/Kar2p in protein folding
14. Identification and characterization of polycystin-2, the PKD2 gene product
15. Identification and localization of two brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors in a macromolecular complex
16. Light and electron microscopical localization of concanavalin A lectin binding sites in rat epiphyseal chondrocytes
17. Human follicle stimulating hormone receptor variants lacking transmembrane domains display altered post-translation conformations
18. Alexa dyes, a series of new fluorescent dyes that yield exceptionally bright, phostostable conjugates
19. Active mitochondria surrounding the pancreatic acinar granule region prevent spreading of inositol triphosphate-evoked local cytosolic Ca(2+) signals
20. Signal-mediated sorting of membrane proteins between the endoplasmic reticulum and the Golgi apparatus
21. The vasopressin precursors is not processed in the hypothalamus of Wolfran syndrom patients with diabetes insipidus: Evidence for the involvement of PC2 and 7B2
22. Localization and possible functions of presenilins in brain
23. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytoxicity by amyloid-beta
24. Psychiatric disorders and mutations at the Wolfram syndrome locus
25. Psychiatric disorders in 36 families with Wolfram syndrome
26. Studies with antipeptide antibody suggest the presence of at least two types of glucose transporter in rat brain an adipocyte
27. Effects of ATP on the release of hsp 70 and hsp 40 from the nucleus in heat-shocked HeLa cells
28. An aromatase-associated cytoplasmic inclusion, the 'stigmoid body', in the rat brain: I. Distribution in the forebrain
29. Isolation of full-length cDNA of mouse PAX4 gene and identification of its human homologue