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Volumn 58, Issue 4, 2009, Pages 894-905

TCF7L2 regulates late events in insulin secretion from pancreatic islet β-cells

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CALCIUM ION; GLUCOSE; INSULIN; MESSENGER RNA; MUNC18 PROTEIN; POTASSIUM CHLORIDE; RNA; SYNTAXIN 1A; TRANSCRIPTION FACTOR 7 LIKE 2;

EID: 64649105053     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db08-1187     Document Type: Article
Times cited : (175)

References (44)
  • 1
    • 0035856920 scopus 로고    scopus 로고
    • Global and societal implications of the diabetes epidemic
    • Zimmet P, Alberti KG, Shaw J: Global and societal implications of the diabetes epidemic. Nature 414:782-787, 2001
    • (2001) Nature , vol.414 , pp. 782-787
    • Zimmet, P.1    Alberti, K.G.2    Shaw, J.3
  • 2
    • 43049101539 scopus 로고    scopus 로고
    • The beta-cell in type 2 diabetes and in obesity
    • Rutter GA, Parton LE: The beta-cell in type 2 diabetes and in obesity. Front Horm Res 36:118-134, 2008
    • (2008) Front Horm Res , vol.36 , pp. 118-134
    • Rutter, G.A.1    Parton, L.E.2
  • 3
    • 0034750833 scopus 로고    scopus 로고
    • Genetic determinants of type 2 diabetes mellitus
    • Busch CP, Hegele RA: Genetic determinants of type 2 diabetes mellitus. Clin Genet 60:243-254, 2001
    • (2001) Clin Genet , vol.60 , pp. 243-254
    • Busch, C.P.1    Hegele, R.A.2
  • 6
    • 0026937234 scopus 로고    scopus 로고
    • Stoffel M, Patel P, Lo YM, Hattersley AT, Lucassen AM, Page R, Bell JI, Bell GI, Turner RC, Wainscoat JS: Missense glucokinase mutation in maturity- onset diabetes of the young and mutation screening in late-onset diabetes. Nat Genet 2:153-156, 1992
    • Stoffel M, Patel P, Lo YM, Hattersley AT, Lucassen AM, Page R, Bell JI, Bell GI, Turner RC, Wainscoat JS: Missense glucokinase mutation in maturity- onset diabetes of the young and mutation screening in late-onset diabetes. Nat Genet 2:153-156, 1992
  • 7
    • 34548032087 scopus 로고    scopus 로고
    • Genome-wide association studies provide new insights into type 2 diabetes aetiology
    • Frayling TM: Genome-wide association studies provide new insights into type 2 diabetes aetiology. Nat Rev Genet 8:657-662, 2007
    • (2007) Nat Rev Genet , vol.8 , pp. 657-662
    • Frayling, T.M.1
  • 8
    • 34249888775 scopus 로고    scopus 로고
    • Saxena R, Voight BF, Lyssenko V, Burtt NP, de Bakker PI, Chen H, Roix JJ, Kathiresan S, Hirschhorn JN, Daly MJ, Hughes TE, Groop L, Altshuler D, Almgren P, Florez JC, Meyer J, Ardlie K, Bengtsson BK, Isomaa B, Lettre G, Lindblad U, Lyon HN, Melander O, Newton-Cheh C, Nilsson P, Orho-Melander M, Rastam L, Speliotes EK, Taskinen MR, Tuomi T, Guiducci C, Berglund A, Carlson J, Gianniny L, Hackett R, Hall L, Holmkvist J, Laurila E, Sjogren M, Sterner M, Surti A, Svensson M, Svensson M, Tewhey R, Blumenstiel B, Parkin M, Defelice M, Barry R, Brodeur W, Camarata J, Chia N, Fava M, Gibbons J, Handsaker B, Healy C, Nguyen K, Gates C, Sougnez C, Gage D, Nizzari M, Gabriel SB, Chirn GW, Ma Q, Parikh H, Richardson D, Ricke D, Purcell S: Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 316:1331-1336, 2007
    • Saxena R, Voight BF, Lyssenko V, Burtt NP, de Bakker PI, Chen H, Roix JJ, Kathiresan S, Hirschhorn JN, Daly MJ, Hughes TE, Groop L, Altshuler D, Almgren P, Florez JC, Meyer J, Ardlie K, Bengtsson BK, Isomaa B, Lettre G, Lindblad U, Lyon HN, Melander O, Newton-Cheh C, Nilsson P, Orho-Melander M, Rastam L, Speliotes EK, Taskinen MR, Tuomi T, Guiducci C, Berglund A, Carlson J, Gianniny L, Hackett R, Hall L, Holmkvist J, Laurila E, Sjogren M, Sterner M, Surti A, Svensson M, Svensson M, Tewhey R, Blumenstiel B, Parkin M, Defelice M, Barry R, Brodeur W, Camarata J, Chia N, Fava M, Gibbons J, Handsaker B, Healy C, Nguyen K, Gates C, Sougnez C, Gage D, Nizzari M, Gabriel SB, Chirn GW, Ma Q, Parikh H, Richardson D, Ricke D, Purcell S: Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 316:1331-1336, 2007
  • 11
    • 32544451924 scopus 로고    scopus 로고
    • Grant SF, Thorleifsson G, Reynisdottir I, Benediktsson R, Manolescu A, Sainz J, Helgason A, Stefansson H, Emilsson V, Helgadottir A, Styrkarsdottir U, Magnusson KP, Walters GB, Palsdottir E, Jonsdottir T, Gudmundsdottir T, Gylfason A, Saemundsdottir J, Wilensky RL, Reilly MP, Rader DJ, Bagger Y, Christiansen C, Gudnason V, Sigurdsson G, Thorsteinsdottir U, Gulcher JR, Kong A, Stefansson K: Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet 38:320-323, 2006
    • Grant SF, Thorleifsson G, Reynisdottir I, Benediktsson R, Manolescu A, Sainz J, Helgason A, Stefansson H, Emilsson V, Helgadottir A, Styrkarsdottir U, Magnusson KP, Walters GB, Palsdottir E, Jonsdottir T, Gudmundsdottir T, Gylfason A, Saemundsdottir J, Wilensky RL, Reilly MP, Rader DJ, Bagger Y, Christiansen C, Gudnason V, Sigurdsson G, Thorsteinsdottir U, Gulcher JR, Kong A, Stefansson K: Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet 38:320-323, 2006
  • 13
    • 33750594321 scopus 로고    scopus 로고
    • Variant of transcription factor 7-like 2 (TCF7L2) gene and the risk of type 2 diabetes in large cohorts of US women and men
    • Zhang C, Qi L, Hunter DJ, Meigs JB, Manson JE, van Dam RM, Hu FB: Variant of transcription factor 7-like 2 (TCF7L2) gene and the risk of type 2 diabetes in large cohorts of US women and men. Diabetes 55:2645-2648, 2006
    • (2006) Diabetes , vol.55 , pp. 2645-2648
    • Zhang, C.1    Qi, L.2    Hunter, D.J.3    Meigs, J.B.4    Manson, J.E.5    van Dam, R.M.6    Hu, F.B.7
  • 14
    • 33845939675 scopus 로고    scopus 로고
    • TCF7L2: The biggest story in diabetes genetics since HLA?
    • Zeggini E, McCarthy MI: TCF7L2: the biggest story in diabetes genetics since HLA? Diabetologia 50:1-4, 2007
    • (2007) Diabetologia , vol.50 , pp. 1-4
    • Zeggini, E.1    McCarthy, M.I.2
  • 19
    • 34447131039 scopus 로고    scopus 로고
    • Transcription factor 7-like 2 polymorphisms and type 2 diabetes, glucose homeostasis traits and gene expression in US participants of European and African descent
    • Elbein SC, Chu WS, Das SK, Yao-Borengasser A, Hasstedt SJ, Wang H, Rasouli N, Kern PA: Transcription factor 7-like 2 polymorphisms and type 2 diabetes, glucose homeostasis traits and gene expression in US participants of European and African descent. Diabetologia 50:1621-1630, 2007
    • (2007) Diabetologia , vol.50 , pp. 1621-1630
    • Elbein, S.C.1    Chu, W.S.2    Das, S.K.3    Yao-Borengasser, A.4    Hasstedt, S.J.5    Wang, H.6    Rasouli, N.7    Kern, P.A.8
  • 21
    • 34247855851 scopus 로고    scopus 로고
    • Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion
    • Wang J, Kuusisto J, Vanttinen M, Kuulasmaa T, Lindstrom J, Tuomilehto J, Uusitupa M, Laakso M: Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion. Diabetologia 50:1192-1200, 2007
    • (2007) Diabetologia , vol.50 , pp. 1192-1200
    • Wang, J.1    Kuusisto, J.2    Vanttinen, M.3    Kuulasmaa, T.4    Lindstrom, J.5    Tuomilehto, J.6    Uusitupa, M.7    Laakso, M.8
  • 22
    • 0031848068 scopus 로고    scopus 로고
    • Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
    • Korinek V, Barker N, Moerer P, van DE, Huls G, Peters PJ, Clevers H: Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nat Genet 19:379-383, 1998
    • (1998) Nat Genet , vol.19 , pp. 379-383
    • Korinek, V.1    Barker, N.2    Moerer, P.3    van, D.E.4    Huls, G.5    Peters, P.J.6    Clevers, H.7
  • 24
    • 0025281303 scopus 로고
    • Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: Special reference to expression of glucose transporter isoforms
    • Miyazaki J, Araki K, Yamato E, Ikegami H, Asano T, Shibasaki Y, Oka Y, Yamamura K: Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms. Endocrinology 127:126-132, 1990
    • (1990) Endocrinology , vol.127 , pp. 126-132
    • Miyazaki, J.1    Araki, K.2    Yamato, E.3    Ikegami, H.4    Asano, T.5    Shibasaki, Y.6    Oka, Y.7    Yamamura, K.8
  • 25
    • 0034006587 scopus 로고    scopus 로고
    • Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion
    • Hohmeier HE, Mulder H, Chen G, Henkel-Rieger R, Prentki M, Newgard CB: Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion. Diabetes 49:424-430, 2000
    • (2000) Diabetes , vol.49 , pp. 424-430
    • Hohmeier, H.E.1    Mulder, H.2    Chen, G.3    Henkel-Rieger, R.4    Prentki, M.5    Newgard, C.B.6
  • 26
    • 20044394745 scopus 로고    scopus 로고
    • Glucose or insulin, but not zinc ions, inhibit glucagon secretion from mouse pancreatic alpha-cells
    • Ravier MA, Rutter GA: Glucose or insulin, but not zinc ions, inhibit glucagon secretion from mouse pancreatic alpha-cells. Diabetes 54:1789-1797, 2005
    • (2005) Diabetes , vol.54 , pp. 1789-1797
    • Ravier, M.A.1    Rutter, G.A.2
  • 27
    • 0033919717 scopus 로고    scopus 로고
    • Acute overexpression of lactate dehydro- genase-A perturbs beta-cell mitochondrial metabolism and insulin secretion
    • Ainscow EK, Zhao C, Rutter GA: Acute overexpression of lactate dehydro- genase-A perturbs beta-cell mitochondrial metabolism and insulin secretion. Diabetes 49:1149-1155, 2000
    • (2000) Diabetes , vol.49 , pp. 1149-1155
    • Ainscow, E.K.1    Zhao, C.2    Rutter, G.A.3
  • 29
    • 0030043256 scopus 로고    scopus 로고
    • Temporal patterns of changes in ATP/ADP ratio, glucose 6-phosphate and cytoplasmic free Ca2+ in glucose-stimulated pancreatic beta-cells
    • Nilsson T, Schultz V, Berggren PO, Corkey BE, Tornheim K: Temporal patterns of changes in ATP/ADP ratio, glucose 6-phosphate and cytoplasmic free Ca2+ in glucose-stimulated pancreatic beta-cells. Biochem J 314:91-94, 1996
    • (1996) Biochem J , vol.314 , pp. 91-94
    • Nilsson, T.1    Schultz, V.2    Berggren, P.O.3    Corkey, B.E.4    Tornheim, K.5
  • 32
    • 33750562388 scopus 로고    scopus 로고
    • Ca2+ microdomains and the control of insulin secretion
    • Rutter GA, Tsuboi T, Ravier MA: Ca2+ microdomains and the control of insulin secretion. Cell Calcium 40:539 -551, 2006
    • (2006) Cell Calcium , vol.40 , pp. 539-551
    • Rutter, G.A.1    Tsuboi, T.2    Ravier, M.A.3
  • 33
    • 10344258585 scopus 로고    scopus 로고
    • Protein kinase activation increases insulin secretion by sensitizing the secretory machinery to Ca2+
    • Wan QF, Dong Y, Yang H, Lou X, Ding J, Xu T: Protein kinase activation increases insulin secretion by sensitizing the secretory machinery to Ca2+. J Gen Physiol 124:653-662, 2004
    • (2004) J Gen Physiol , vol.124 , pp. 653-662
    • Wan, Q.F.1    Dong, Y.2    Yang, H.3    Lou, X.4    Ding, J.5    Xu, T.6
  • 34
    • 36049049393 scopus 로고    scopus 로고
    • Dual modes of Munc18-1/SNARE interactions are coupled by functionally critical binding to syntaxin-1 N terminus
    • Khvotchev M, Dulubova I, Sun J, Dai H, Rizo J, Sudhof TC: Dual modes of Munc18-1/SNARE interactions are coupled by functionally critical binding to syntaxin-1 N terminus. J Neurosci 27:12147-12155, 2007
    • (2007) J Neurosci , vol.27 , pp. 12147-12155
    • Khvotchev, M.1    Dulubova, I.2    Sun, J.3    Dai, H.4    Rizo, J.5    Sudhof, T.C.6
  • 36
    • 31344433667 scopus 로고    scopus 로고
    • Activation of beta-catenin signaling in prostate cancer by peptidyl-prolyl isomerase Pin1-mediated abrogation of the androgen receptor-beta-catenin interaction
    • Chen SY, Wulf G, Zhou XZ, Rubin MA, Lu KP, Balk SP: Activation of beta-catenin signaling in prostate cancer by peptidyl-prolyl isomerase Pin1-mediated abrogation of the androgen receptor-beta-catenin interaction. Mol Cell Biol 26:929-939, 2006
    • (2006) Mol Cell Biol , vol.26 , pp. 929-939
    • Chen, S.Y.1    Wulf, G.2    Zhou, X.Z.3    Rubin, M.A.4    Lu, K.P.5    Balk, S.P.6
  • 38
    • 8744220599 scopus 로고    scopus 로고
    • Mechanisms of dense core vesicle recapture following 'kiss and run' ('cavicapture') exocytosis in insulinsecreting cells
    • Tsuboi T, McMahon HT, Rutter GA: Mechanisms of dense core vesicle recapture following 'kiss and run' ('cavicapture') exocytosis in insulinsecreting cells. J Biol Chem 279:47115-47124, 2004
    • (2004) J Biol Chem , vol.279 , pp. 47115-47124
    • Tsuboi, T.1    McMahon, H.T.2    Rutter, G.A.3
  • 40
    • 47749089779 scopus 로고    scopus 로고
    • A genome-wide RNAi screen for Wnt/+ -catenin pathway components identifies unexpected roles for TCF transcription factors in cancer
    • Tang W, Dodge M, Gundapaneni D, Michnoff C, Roth M, Lum L: A genome-wide RNAi screen for Wnt/+ -catenin pathway components identifies unexpected roles for TCF transcription factors in cancer. Proc Natl Acad Sci 105:9697-9702, 2008
    • (2008) Proc Natl Acad Sci , vol.105 , pp. 9697-9702
    • Tang, W.1    Dodge, M.2    Gundapaneni, D.3    Michnoff, C.4    Roth, M.5    Lum, L.6
  • 42
    • 33644772589 scopus 로고    scopus 로고
    • Impaired gene and protein expression of exocytotic soluble N-ethylmaleimide attachment protein receptor complex proteins in pancreatic islets of type 2 diabetic patients
    • Ostenson CG, Gaisano H, Sheu L, Tibell A, Bartfai T: Impaired gene and protein expression of exocytotic soluble N-ethylmaleimide attachment protein receptor complex proteins in pancreatic islets of type 2 diabetic patients. Diabetes 55:435-440, 2006
    • (2006) Diabetes , vol.55 , pp. 435-440
    • Ostenson, C.G.1    Gaisano, H.2    Sheu, L.3    Tibell, A.4    Bartfai, T.5
  • 44
    • 0032775945 scopus 로고    scopus 로고
    • Blockade of membrane transport and disassembly of the Golgi complex by expression of syntaxin 1A in neurosecretion-incompetent cells: Prevention by rbSEC1
    • Rowe J, Corradi N, Malosio ML, Taverna E, Halban P, Meldolesi J, Rosa P: Blockade of membrane transport and disassembly of the Golgi complex by expression of syntaxin 1A in neurosecretion-incompetent cells: prevention by rbSEC1. J Cell Sci 112:1865-1877, 1999
    • (1999) J Cell Sci , vol.112 , pp. 1865-1877
    • Rowe, J.1    Corradi, N.2    Malosio, M.L.3    Taverna, E.4    Halban, P.5    Meldolesi, J.6    Rosa, P.7


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