The PPARγ2 amino acid polymorphism Pro 12 Ala is prevalent in offspring of Type II diabetic patients and is associated to increased insulin sensitivity in a subgroup of obese subjects

Diabetologia

Volumn 42, Issue 6, 1999, Pages 758-762

  Koch, M ^a,b   Rett, K ^a   Maerker, E ^a   Volk, A ^a   Haist, K ^a   Deninger, M ^a   Renn, W ^a   Haring H U ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b Labor Wagner und Partner   (Germany)

Author keywords

Insulin resistance; Obesity; Peroxisome proliferator activated receptors; Pro 12 Ala mutation; Type II diabetes

Indexed keywords

ALANINE; GLUCOSE; INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PROLINE; CELL RECEPTOR; TRANSCRIPTION FACTOR;

ADIPOCYTE; ADULT; AMINO ACID SUBSTITUTION; ARTICLE; DNA POLYMORPHISM; FEMALE; GLUCOSE CLAMP TECHNIQUE; GLUCOSE TOLERANCE TEST; HETEROZYGOTE DETECTION; HOMOZYGOTE; HUMAN; INSULIN RESISTANCE; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL; RISK FACTOR; CODON; DIABETES MELLITUS; GENETIC POLYMORPHISM; GENETICS; MUTATION; QUANTITATIVE TRAIT;

ADULT; ALANINE; AMINO ACID SUBSTITUTION; CODON; DIABETES MELLITUS; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; INSULIN RESISTANCE; MALE; MUTATION; OBESITY; POLYMORPHISM, GENETIC; PROLINE; QUANTITATIVE TRAIT, HERITABLE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TRANSCRIPTION FACTORS;

EID: 0032589053     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051225     Document Type: Article

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