A KATP channel-dependent pathway within α cells regulates glucagon release from both rodent and human islets of langerhans

PLoS Biology

Volumn 5, Issue 6, 2007, Pages 1236-1247

  MacDonald, Patrick E ^a,b   De Marinis, Yang Zhang ^c   Ramracheya, Reshma ^a   Salehi, Albert ^c   Ma, Xiaosong ^c   Johnson, Paul R V ^a   Cox, Roger ^d   Eliasson, Lena ^c   Rorsman, Patrik ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF ALBERTA   (Canada)

^c LUND UNIVERSITY DIABETES CENTRE   (Sweden)

^d MRC MAMMALIAN GENETICS UNIT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CALCIUM; CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL N TYPE; CELLOBIOSE; CELLULOSE; DIAZOXIDE; GLUCAGON; GLUCOSE; INSULIN; NIFEDIPINE; POTASSIUM CHANNEL; TOLBUTAMIDE; VOLTAGE GATED SODIUM CHANNEL; ZINC; SODIUM CHANNEL;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ELECTRIC ACTIVITY; EXOCYTOSIS; FEMALE; GLUCAGON RELEASE; HORMONE RELEASE; HUMAN; HUMAN CELL; INSULIN RELEASE; MEMBRANE POLARIZATION AND DEPOLARIZATION; MEMBRANE POTENTIAL; NONHUMAN; PANCREAS ISLET; PARACRINE SIGNALING; SIGNAL TRANSDUCTION; ANIMAL; BAGG ALBINO MOUSE; METABOLISM; MOUSE; MOUSE MUTANT; PANCREAS ISLET ALPHA CELL; PHYSIOLOGY; SECRETION;

RODENTIA;

ANIMALS; CALCIUM; CALCIUM CHANNELS, N-TYPE; EXOCYTOSIS; FEMALE; GLUCAGON; GLUCAGON-SECRETING CELLS; GLUCOSE; HUMANS; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; POTASSIUM CHANNELS; SODIUM CHANNELS;

EID: 34250307235     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.0050143     Document Type: Article

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