Identification and functional characterization of melatonin Mel 1a receptors in pancreatic β cells: Potential role in incretin-mediated cell function by sensitization of cAMP signaling

Molecular and Cellular Endocrinology

Volumn 191, Issue 2, 2002, Pages 157-166

  Kemp, Daniel M ^a   Ubeda, Mariano ^a   Habener, Joel F ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Glucagon like peptide 1; Insulin; Melatonin 1a receptor; Pancreatic cell

Indexed keywords

2 IODOBUTANOYLMETHOXYTRYPTAMINE; 2 IODOMELATONIN; 4 PHENYL 2 PROPIONAMIDOTETRALIN; 6 CHLOROMELATONIN; CYCLIC AMP; FORSKOLIN; G PROTEIN COUPLED RECEPTOR; GLUCAGON LIKE PEPTIDE 1; INSULIN; LUZINDOLE; MELATONIN; MELATONIN 1A RECEPTOR; MELATONIN 1B RECEPTOR; MELATONIN RECEPTOR; N ACETYLSEROTONIN; TETRALIN DERIVATIVE; TRYPTAMINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL FUNCTION; CELL ISOLATION; CELL TYPE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; GENE EXPRESSION; INSULIN RELEASE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RAT; REPORTER GENE; SENSITIZATION; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE; CIRCADIAN RHYTHM; CYCLIC AMP; GLUCAGON; GLUCAGON-LIKE PEPTIDE 1; GLUCAGON-LIKE PEPTIDES; ISLETS OF LANGERHANS; MELATONIN; PEPTIDE FRAGMENTS; PROTEIN PRECURSORS; RATS; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, MELATONIN; SECOND MESSENGER SYSTEMS;

EID: 0037077043     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(02)00064-3     Document Type: Article

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