A common genetic variant in WFS1 determines impaired glucagon-like peptide-1-induced insulin secretion

Diabetologia

Volumn 52, Issue 6, 2009, Pages 1075-1082

  Schafer S A ^a   Mussig K ^a   Staiger, H ^a   MacHicao, F ^a   Stefan, N ^a   Gallwitz, B ^a   Haring H U ^a   Fritsche, A ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

Endoplasmic reticulum; GLP 1; Incretin; Pancreatic beta cell; Single nucleotide polymorphism; Wolfram syndrome; Wolframin

Indexed keywords

ARGININE; GLUCAGON LIKE PEPTIDE 1; INSULIN;

ADULT; ALLELE; ARTICLE; BODY MASS; EUGLYCEMIC HYPERINSULINEMIC CLAMP; FEMALE; GENE; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; HIGH RISK POPULATION; HUMAN; HUMAN EXPERIMENT; HYPERGLYCEMIC CLAMP; INSULIN RELEASE; INSULIN SENSITIVITY; INTRAVENOUS GLUCOSE TOLERANCE TEST; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; WFS1 GENE;

ADULT; DIABETES MELLITUS, TYPE 2; FEMALE; GENOTYPE; GLUCAGON-LIKE PEPTIDE 1; GLUCOSE CLAMP TECHNIQUE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN; ISLETS OF LANGERHANS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 67349190497     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-009-1344-5     Document Type: Article

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