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Volumn 5, Issue , 2007, Pages

Pancreatic islet cell therapy for type I diabetes: Understanding the effects of glucose stimulation on islets in order to produce better islets for transplantation

Author keywords

[No Author keywords available]

Indexed keywords

DACLIZUMAB; GLUCOSE; INSULIN; MESSENGER RNA; RAPAMYCIN; TACROLIMUS;

EID: 33846679496     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-5-1     Document Type: Review
Times cited : (24)

References (119)
  • 1
    • 0041666293 scopus 로고    scopus 로고
    • Beta-cell function and the development of diabetes-related complications in the diabetes control and complications trial
    • 12610045
    • Steffes MW Sibley S Jackson M Thomas W Beta-cell function and the development of diabetes-related complications in the diabetes control and complications trial Diabetes Care 2003 26 3 832-836 12610045
    • (2003) Diabetes Care , vol.26 , Issue.3 , pp. 832-836
    • Steffes, M.W.1    Sibley, S.2    Jackson, M.3    Thomas, W.4
  • 2
    • 22244456740 scopus 로고    scopus 로고
    • Pancreas transplant outcomes for United States (US) and non-US cases as reported to the United Network for Organ Sharing (UNOS) and the International Pancreas Transplant Registry (IPTR) as of June 2004
    • 10.1111/j.1399-0012.2005.00378.x 16008587
    • Gruessner AC Sutherland DE Pancreas transplant outcomes for United States (US) and non-US cases as reported to the United Network for Organ Sharing (UNOS) and the International Pancreas Transplant Registry (IPTR) as of June 2004 Clin Transplant 2005 19 4 433-455 10.1111/ j.1399-0012.2005.00378.x 16008587
    • (2005) Clin Transplant , vol.19 , Issue.4 , pp. 433-455
    • Gruessner, A.C.1    Sutherland, D.E.2
  • 4
    • 0344630326 scopus 로고    scopus 로고
    • Survival after pancreas transplantation in patients with diabetes and preserved kidney function
    • 10.1001/jama.290.21.2817 14657065
    • Venstrom JM McBride MA Rother KI Hirshberg B Orchard TJ Harlan DM Survival after pancreas transplantation in patients with diabetes and preserved kidney function Jama 2003 290 21 2817-2823 10.1001/ jama.290.21.2817 14657065
    • (2003) Jama , vol.290 , Issue.21 , pp. 2817-2823
    • Venstrom, J.M.1    McBride, M.A.2    Rother, K.I.3    Hirshberg, B.4    Orchard, T.J.5    Harlan, D.M.6
  • 5
    • 10044232979 scopus 로고    scopus 로고
    • Mortality assessment for pancreas transplants
    • 10.1111/j.1600-6143.2004.00667.x 15575904
    • Gruessner RW Sutherland DE Gruessner AC Mortality assessment for pancreas transplants Am J Transplant 2004 4 12 2018-2026 10.1111/ j.1600-6143.2004.00667.x 15575904
    • (2004) Am J Transplant , vol.4 , Issue.12 , pp. 2018-2026
    • Gruessner, R.W.1    Sutherland, D.E.2    Gruessner, A.C.3
  • 6
    • 0015386234 scopus 로고
    • Transplantation of intact pancreatic islets in rats
    • 4262169
    • Ballinger WF Lacy PE Transplantation of intact pancreatic islets in rats Surgery 1972 72 2 175-186 4262169
    • (1972) Surgery , vol.72 , Issue.2 , pp. 175-186
    • Ballinger, W.F.1    Lacy, P.E.2
  • 8
    • 0018885443 scopus 로고
    • A long-term functioning human pancreatic islet allotransplant
    • 10.1097/00007890-198001000-00017 6768175
    • Largiader F Kolb E Binswanger U A long-term functioning human pancreatic islet allotransplant Transplantation 1980 29 1 76-77 10.1097/ 00007890-198001000-00017 6768175
    • (1980) Transplantation , vol.29 , Issue.1 , pp. 76-77
    • Largiader, F.1    Kolb, E.2    Binswanger, U.3
  • 11
    • 0023912253 scopus 로고
    • Automated method for isolation of human pancreatic islets
    • 3288530
    • Ricordi C Lacy PE Finke EH Olack BJ Scharp DW Automated method for isolation of human pancreatic islets Diabetes 1988 37 4 413-420 3288530
    • (1988) Diabetes , vol.37 , Issue.4 , pp. 413-420
    • Ricordi, C.1    Lacy, P.E.2    Finke, E.H.3    Olack, B.J.4    Scharp, D.W.5
  • 12
    • 33749042562 scopus 로고    scopus 로고
    • Diabetes cure - Is the glass half full?
    • 10.1056/NEJMe068183 17005956
    • Bromberg JS LeRoith D Diabetes cure - is the glass half full? N Engl J Med 2006 355 13 1372-1374 10.1056/NEJMe068183 17005956
    • (2006) N Engl J Med , vol.355 , Issue.13 , pp. 1372-1374
    • Bromberg, J.S.1    LeRoith, D.2
  • 13
    • 0034721255 scopus 로고    scopus 로고
    • Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
    • 10.1056/NEJM200007273430401 10911004
    • Shapiro AM Lakey JR Ryan EA Korbutt GS Toth E Warnock GL Kneteman NM Rajotte RV Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen N Engl J Med 2000 343 4 230-238 10.1056/NEJM200007273430401 10911004
    • (2000) N Engl J Med , vol.343 , Issue.4 , pp. 230-238
    • Shapiro, A.M.1    Lakey, J.R.2    Ryan, E.A.3    Korbutt, G.S.4    Toth, E.5    Warnock, G.L.6    Kneteman, N.M.7    Rajotte, R.V.8
  • 14
    • 9644294263 scopus 로고    scopus 로고
    • Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus
    • 518676 15467822 10.1172/JCI200423235
    • Rother KI Harlan DM Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus J Clin Invest 2004 114 7 877-883 518676 15467822 10.1172/JCI200423235
    • (2004) J Clin Invest , vol.114 , Issue.7 , pp. 877-883
    • Rother, K.I.1    Harlan, D.M.2
  • 15
    • 15744381397 scopus 로고    scopus 로고
    • Pancreatic islet transplantation
    • quiz e75 539048 15630467 10.1371/journal.pmed.0010058
    • Naftanel MA Harlan DM Pancreatic islet transplantation PLoS Med 2004 1 3 e58; quiz e75 539048 15630467 10.1371/journal.pmed.0010058
    • (2004) PLoS Med , vol.1 , Issue.3
    • Naftanel, M.A.1    Harlan, D.M.2
  • 17
    • 10744233137 scopus 로고    scopus 로고
    • Benefits and risks of solitary islet transplantation for type 1 diabetes using steroid-sparing immunosuppression: The National Institutes of Health experience
    • 14633816
    • Hirshberg B Rother KI Digon BJ 3rd Lee J Gaglia JL Hines K Read EJ Chang R Wood BJ Harlan DM Benefits and risks of solitary islet transplantation for type 1 diabetes using steroid-sparing immunosuppression: The National Institutes of Health experience Diabetes Care 2003 26 12 3288-3295 14633816
    • (2003) Diabetes Care , vol.26 , Issue.12 , pp. 3288-3295
    • Hirshberg, B.1    Rother, K.I.2    Digon III, B.J.3    Lee, J.4    Gaglia, J.L.5    Hines, K.6    Read, E.J.7    Chang, R.8    Wood, B.J.9    Harlan, D.M.10
  • 18
    • 3042758642 scopus 로고    scopus 로고
    • Stem-cell therapy for diabetes mellitus
    • 10.1016/S0140-6736(04)16635-X 15246735
    • Hussain MA Theise ND Stem-cell therapy for diabetes mellitus Lancet 2004 364 9429 203-205 10.1016/S0140-6736(04)16635-X 15246735
    • (2004) Lancet , vol.364 , Issue.9429 , pp. 203-205
    • Hussain, M.A.1    Theise, N.D.2
  • 19
    • 13744261497 scopus 로고    scopus 로고
    • Regeneration of the pancreatic beta cell
    • 539206 15630433 10.1172/JCI200523935
    • Trucco M Regeneration of the pancreatic beta cell J Clin Invest 2005 115 1 5-12 539206 15630433 10.1172/JCI200523935
    • (2005) J Clin Invest , vol.115 , Issue.1 , pp. 5-12
    • Trucco, M.1
  • 20
    • 8644277274 scopus 로고    scopus 로고
    • Adult pancreas generates multipotent stem cells and pancreatic and nonpancreatic progeny
    • 10.1634/stemcells.22-6-1070 15536197
    • Choi Y Ta M Atouf F Lumelsky N Adult pancreas generates multipotent stem cells and pancreatic and nonpancreatic progeny Stem Cells 2004 22 6 1070-1084 10.1634/stemcells.22-6-1070 15536197
    • (2004) Stem Cells , vol.22 , Issue.6 , pp. 1070-1084
    • Choi, Y.1    Ta, M.2    Atouf, F.3    Lumelsky, N.4
  • 22
    • 0035991639 scopus 로고    scopus 로고
    • Identification of insulin-producing cells derived from embryonic stem cells by zinc-chelating dithizone
    • 10.1634/stemcells.20-4-284 12110697
    • Shiroi A Yoshikawa M Yokota H Fukui H Ishizaka S Tatsumi K Takahashi Y Identification of insulin-producing cells derived from embryonic stem cells by zinc-chelating dithizone Stem Cells 2002 20 4 284-292 10.1634/ stemcells.20-4-284 12110697
    • (2002) Stem Cells , vol.20 , Issue.4 , pp. 284-292
    • Shiroi, A.1    Yoshikawa, M.2    Yokota, H.3    Fukui, H.4    Ishizaka, S.5    Tatsumi, K.6    Takahashi, Y.7
  • 23
    • 0042767581 scopus 로고    scopus 로고
    • Pancreatic precursors and differentiated islet cell types from murine embryonic stem cells: An in vitro model to study islet differentiation
    • 12882918
    • Kahan BW Jacobson LM Hullett DA Ochoada JM Oberley TD Lang KM Odorico JS Pancreatic precursors and differentiated islet cell types from murine embryonic stem cells: An in vitro model to study islet differentiation Diabetes 2003 52 8 2016-2024 12882918
    • (2003) Diabetes , vol.52 , Issue.8 , pp. 2016-2024
    • Kahan, B.W.1    Jacobson, L.M.2    Hullett, D.A.3    Ochoada, J.M.4    Oberley, T.D.5    Lang, K.M.6    Odorico, J.S.7
  • 24
    • 0035906902 scopus 로고    scopus 로고
    • Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets
    • 10.1126/science.1058866 11326082
    • Lumelsky N Blondel O Laeng P Velasco I Ravin R McKay R Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets Science 2001 292 5520 1389-1394 10.1126/ science.1058866 11326082
    • (2001) Science , vol.292 , Issue.5520 , pp. 1389-1394
    • Lumelsky, N.1    Blondel, O.2    Laeng, P.3    Velasco, I.4    Ravin, R.5    McKay, R.6
  • 25
    • 0037058934 scopus 로고    scopus 로고
    • Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cells
    • 138572 12441403 10.1073/pnas.252618999
    • Hori Y Rulifson IC Tsai BC Heit JJ Cahoy JD Kim SK Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cells Proc Natl Acad Sci U S A 2002 99 25 16105-16110 138572 12441403 10.1073/pnas.252618999
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.25 , pp. 16105-16110
    • Hori, Y.1    Rulifson, I.C.2    Tsai, B.C.3    Heit, J.J.4    Cahoy, J.D.5    Kim, S.K.6
  • 26
    • 0037417958 scopus 로고    scopus 로고
    • Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells
    • 298715 12525695 10.1073/pnas.0237371100
    • Blyszczuk P Czyz J Kania G Wagner M Roll U St-Onge L Wobus AM Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells Proc Natl Acad Sci U S A 2003 100 3 998-1003 298715 12525695 10.1073/pnas.0237371100
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.3 , pp. 998-1003
    • Blyszczuk, P.1    Czyz, J.2    Kania, G.3    Wagner, M.4    Roll, U.5    St-Onge, L.6    Wobus, A.M.7
  • 29
    • 3042785984 scopus 로고    scopus 로고
    • In vivo and in vitro characterization of insulin-producing cells obtained from murine bone marrow
    • 15220196
    • Tang DQ Cao LZ Burkhardt BR Xia CQ Litherland SA Atkinson MA Yang LJ In vivo and in vitro characterization of insulin-producing cells obtained from murine bone marrow Diabetes 2004 53 7 1721-1732 15220196
    • (2004) Diabetes , vol.53 , Issue.7 , pp. 1721-1732
    • Tang, D.Q.1    Cao, L.Z.2    Burkhardt, B.R.3    Xia, C.Q.4    Litherland, S.A.5    Atkinson, M.A.6    Yang, L.J.7
  • 30
    • 0034068602 scopus 로고    scopus 로고
    • Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia
    • 10.1038/75050 10802714
    • Ferber S Halkin A Cohen H Ber I Einav Y Goldberg I Barshack I Seijffers R Kopolovic J Kaiser N Karasik A Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia Nat Med 2000 6 5 568-572 10.1038/ 75050 10802714
    • (2000) Nat Med , vol.6 , Issue.5 , pp. 568-572
    • Ferber, S.1    Halkin, A.2    Cohen, H.3    Ber, I.4    Einav, Y.5    Goldberg, I.6    Barshack, I.7    Seijffers, R.8    Kopolovic, J.9    Kaiser, N.10    Karasik, A.11
  • 35
    • 0034507714 scopus 로고    scopus 로고
    • Regulation of insulin gene transcription
    • 10.1006/scdb.2000.0171 10966856
    • Ohneda K Ee H German M Regulation of insulin gene transcription Semin Cell Dev Biol 2000 11 4 227-233 10.1006/scdb.2000.0171 10966856
    • (2000) Semin Cell Dev Biol , vol.11 , Issue.4 , pp. 227-233
    • Ohneda, K.1    Ee, H.2    German, M.3
  • 37
    • 0033962883 scopus 로고    scopus 로고
    • The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter
    • 85207 10629047 10.1128/MCB.20.3.900-911.2000
    • Ohneda K Mirmira RG Wang J Johnson JD German MS The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter Mol Cell Biol 2000 20 3 900-911 85207 10629047 10.1128/MCB.20.3.900-911.2000
    • (2000) Mol Cell Biol , vol.20 , Issue.3 , pp. 900-911
    • Ohneda, K.1    Mirmira, R.G.2    Wang, J.3    Johnson, J.D.4    German, M.S.5
  • 39
    • 0037147306 scopus 로고    scopus 로고
    • MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene
    • 10.1074/jbc.M206796200 12368292
    • Kataoka K Han SI Shioda S Hirai M Nishizawa M Handa H MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene J Biol Chem 2002 277 51 49903-49910 10.1074/jbc.M206796200 12368292
    • (2002) J Biol Chem , vol.277 , Issue.51 , pp. 49903-49910
    • Kataoka, K.1    Han, S.I.2    Shioda, S.3    Hirai, M.4    Nishizawa, M.5    Handa, H.6
  • 40
    • 1542271011 scopus 로고    scopus 로고
    • Differentially expressed Maf family transcription factors, c-Maf and MafA, activate glucagon and insulin gene expression in pancreatic islet alpha- and beta-cells
    • 10.1677/jme.0.0320009 14765989
    • Kataoka K Shioda S Ando K Sakagami K Handa H Yasuda K Differentially expressed Maf family transcription factors, c-Maf and MafA, activate glucagon and insulin gene expression in pancreatic islet alpha- and beta-cells J Mol Endocrinol 2004 32 1 9-20 10.1677/jme.0.0320009 14765989
    • (2004) J Mol Endocrinol , vol.32 , Issue.1 , pp. 9-20
    • Kataoka, K.1    Shioda, S.2    Ando, K.3    Sakagami, K.4    Handa, H.5    Yasuda, K.6
  • 41
    • 1542297749 scopus 로고    scopus 로고
    • The MafA transcription factor appears to be responsible for tissue-specific expression of insulin
    • 365722 14973194 10.1073/pnas.0306233101
    • Matsuoka TA Artner I Henderson E Means A Sander M Stein R The MafA transcription factor appears to be responsible for tissue-specific expression of insulin Proc Natl Acad Sci U S A 2004 101 9 2930-2933 365722 14973194 10.1073/pnas.0306233101
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.9 , pp. 2930-2933
    • Matsuoka, T.A.1    Artner, I.2    Henderson, E.3    Means, A.4    Sander, M.5    Stein, R.6
  • 42
    • 0023610730 scopus 로고
    • Proteolytic maturation of insulin is a post-Golgi event which occurs in acidifying clathrin-coated secretory vesicles
    • 10.1016/0092-8674(87)90624-6 3555846
    • Orci L Ravazzola M Storch MJ Anderson RG Vassalli JD Perrelet A Proteolytic maturation of insulin is a post-Golgi event which occurs in acidifying clathrin-coated secretory vesicles Cell 1987 49 6 865-868 10.1016/0092-8674(87)90624-6 3555846
    • (1987) Cell , vol.49 , Issue.6 , pp. 865-868
    • Orci, L.1    Ravazzola, M.2    Storch, M.J.3    Anderson, R.G.4    Vassalli, J.D.5    Perrelet, A.6
  • 43
    • 0021335764 scopus 로고
    • Insulin, not C-peptide (proinsulin), is present in crinophagic bodies of the pancreatic B-cell
    • 10.1083/jcb.98.1.222 6368567
    • Orci L Ravazzola M Amherdt M Yanaihara C Yanaihara N Halban P Renold AE Perrelet A Insulin, not C-peptide (proinsulin), is present in crinophagic bodies of the pancreatic B-cell J Cell Biol 1984 98 1 222-228 10.1083/jcb.98.1.222 6368567
    • (1984) J Cell Biol , vol.98 , Issue.1 , pp. 222-228
    • Orci, L.1    Ravazzola, M.2    Amherdt, M.3    Yanaihara, C.4    Yanaihara, N.5    Halban, P.6    Renold, A.E.7    Perrelet, A.8
  • 44
    • 32544446451 scopus 로고    scopus 로고
    • Coping with stress: EIF2 kinases and translational control
    • 16246168
    • Wek RC Jiang HY Anthony TG Coping with stress: EIF2 kinases and translational control Biochem Soc Trans 2006 34 Pt 1 7-11 16246168
    • (2006) Biochem Soc Trans , vol.34 , Issue.PART 1 , pp. 7-11
    • Wek, R.C.1    Jiang, H.Y.2    Anthony, T.G.3
  • 45
    • 0036895383 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and the development of diabetes: A review
    • 12475790
    • Harding HP Ron D Endoplasmic reticulum stress and the development of diabetes: A review Diabetes 2002 51 Suppl 3 S455-61 12475790
    • (2002) Diabetes , vol.51 , Issue.SUPPL. 3
    • Harding, H.P.1    Ron, D.2
  • 46
    • 0028786952 scopus 로고
    • Repression of cap-dependent translation by 4E-binding protein 1: Competition with p220 for binding to eukaryotic initiation factor-4E
    • 394685 8521827
    • Haghighat A Mader S Pause A Sonenberg N Repression of cap-dependent translation by 4E-binding protein 1: Competition with p220 for binding to eukaryotic initiation factor-4E Embo J 1995 14 22 5701-5709 394685 8521827
    • (1995) Embo J , vol.14 , Issue.22 , pp. 5701-5709
    • Haghighat, A.1    Mader, S.2    Pause, A.3    Sonenberg, N.4
  • 47
    • 0028034233 scopus 로고
    • Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5′-cap function
    • 10.1038/371762a0 7935836
    • Pause A Belsham GJ Gingras AC Donze O Lin TA Lawrence JC Jr. Sonenberg N Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5′-cap function Nature 1994 371 6500 762-767 10.1038/371762a0 7935836
    • (1994) Nature , vol.371 , Issue.6500 , pp. 762-767
    • Pause, A.1    Belsham, G.J.2    Gingras, A.C.3    Donze, O.4    Lin, T.A.5    Lawrence Jr., J.C.6    Sonenberg, N.7
  • 48
    • 0014336473 scopus 로고
    • Dynamics of insulin secretion by the perfused rat pancreas
    • 4877098
    • Curry DL Bennett LL Grodsky GM Dynamics of insulin secretion by the perfused rat pancreas Endocrinology 1968 83 3 572-584 4877098
    • (1968) Endocrinology , vol.83 , Issue.3 , pp. 572-584
    • Curry, D.L.1    Bennett, L.L.2    Grodsky, G.M.3
  • 49
    • 33644762018 scopus 로고    scopus 로고
    • In Vivo and In Vitro Glucose-Induced Biphasic Insulin Secretion in the Mouse: Pattern and Role of Cytoplasmic Ca2+ and Amplification Signals in {beta}-Cells
    • 10.2337/diabetes.55.02.06.db05-1051 16443779
    • Henquin JC Nenquin M Stiernet P Ahren B In Vivo and In Vitro Glucose-Induced Biphasic Insulin Secretion in the Mouse: Pattern and Role of Cytoplasmic Ca2+ and Amplification Signals in {beta}-Cells Diabetes 2006 55 2 441-451 10.2337/diabetes.55.02.06.db05-1051 16443779
    • (2006) Diabetes , vol.55 , Issue.2 , pp. 441-451
    • Henquin, J.C.1    Nenquin, M.2    Stiernet, P.3    Ahren, B.4
  • 50
    • 27744541052 scopus 로고    scopus 로고
    • Exenatide augments first- and second-phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes
    • 10.1210/jc.2005-1093 16144950
    • Fehse F Trautmann M Holst JJ Halseth AE Nanayakkara N Nielsen LL Fineman MS Kim DD Nauck MA Exenatide augments first- and second-phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes J Clin Endocrinol Metab 2005 90 11 5991-5997 10.1210/ jc.2005-1093 16144950
    • (2005) J Clin Endocrinol Metab , vol.90 , Issue.11 , pp. 5991-5997
    • Fehse, F.1    Trautmann, M.2    Holst, J.J.3    Halseth, A.E.4    Nanayakkara, N.5    Nielsen, L.L.6    Fineman, M.S.7    Kim, D.D.8    Nauck, M.A.9
  • 51
    • 24144458524 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 regulates sequential and compound exocytosis in pancreatic islet beta-cells
    • 16123364
    • Kwan EP Gaisano HY Glucagon-like peptide 1 regulates sequential and compound exocytosis in pancreatic islet beta-cells Diabetes 2005 54 9 2734-2743 16123364
    • (2005) Diabetes , vol.54 , Issue.9 , pp. 2734-2743
    • Kwan, E.P.1    Gaisano, H.Y.2
  • 53
    • 0042879951 scopus 로고    scopus 로고
    • Insulin granule dynamics in pancreatic beta cells
    • 10.1007/s00125-003-1153-1 12879249
    • Rorsman P Renstrom E Insulin granule dynamics in pancreatic beta cells Diabetologia 2003 46 8 1029-1045 10.1007/s00125-003-1153-1 12879249
    • (2003) Diabetologia , vol.46 , Issue.8 , pp. 1029-1045
    • Rorsman, P.1    Renstrom, E.2
  • 54
    • 0032832621 scopus 로고    scopus 로고
    • Identification of the docked granule pool responsible for the first phase of glucose-stimulated insulin secretion
    • 10480595
    • Daniel S Noda M Straub SG Sharp GW Identification of the docked granule pool responsible for the first phase of glucose-stimulated insulin secretion Diabetes 1999 48 9 1686-1690 10480595
    • (1999) Diabetes , vol.48 , Issue.9 , pp. 1686-1690
    • Daniel, S.1    Noda, M.2    Straub, S.G.3    Sharp, G.W.4
  • 55
    • 0018831212 scopus 로고
    • Translational control of proinsulin synthesis by glucose
    • 10.1038/283100a0 6985712
    • Itoh N Okamoto H Translational control of proinsulin synthesis by glucose Nature 1980 283 5742 100-102 10.1038/283100a0 6985712
    • (1980) Nature , vol.283 , Issue.5742 , pp. 100-102
    • Itoh, N.1    Okamoto, H.2
  • 56
    • 0022535308 scopus 로고
    • Translational control of insulin biosynthesis. Evidence for regulation of elongation, initiation and signal-recognition-particle-mediated translational arrest by glucose
    • 1146709 3017307
    • Welsh M Scherberg N Gilmore R Steiner DF Translational control of insulin biosynthesis. Evidence for regulation of elongation, initiation and signal-recognition-particle-mediated translational arrest by glucose Biochem J 1986 235 2 459-467 1146709 3017307
    • (1986) Biochem J , vol.235 , Issue.2 , pp. 459-467
    • Welsh, M.1    Scherberg, N.2    Gilmore, R.3    Steiner, D.F.4
  • 57
    • 33644872401 scopus 로고    scopus 로고
    • In beta-cells, mitochondria integrate and generate metabolic signals controlling insulin secretion
    • 16443386
    • Maechler P Carobbio S Rubi B In beta-cells, mitochondria integrate and generate metabolic signals controlling insulin secretion Int J Biochem Cell Biol 2006 16443386
    • (2006) Int J Biochem Cell Biol
    • Maechler, P.1    Carobbio, S.2    Rubi, B.3
  • 58
    • 0042879894 scopus 로고    scopus 로고
    • Voltage-dependent K(+) channels in pancreatic beta cells: Role, regulation and potential as therapeutic targets
    • 10.1007/s00125-003-1159-8 12830383
    • MacDonald PE Wheeler MB Voltage-dependent K(+) channels in pancreatic beta cells: Role, regulation and potential as therapeutic targets Diabetologia 2003 46 8 1046-1062 10.1007/s00125-003-1159-8 12830383
    • (2003) Diabetologia , vol.46 , Issue.8 , pp. 1046-1062
    • MacDonald, P.E.1    Wheeler, M.B.2
  • 60
    • 0036151862 scopus 로고    scopus 로고
    • Molecular determinants of exocytosis
    • 10.1007/s00424-001-0742-4 11810200
    • Bruns D Jahn R Molecular determinants of exocytosis Pflugers Arch 2002 443 3 333-338 10.1007/s00424-001-0742-4 11810200
    • (2002) Pflugers Arch , vol.443 , Issue.3 , pp. 333-338
    • Bruns, D.1    Jahn, R.2
  • 61
    • 0034511895 scopus 로고    scopus 로고
    • Beta-granule transport and exocytosis
    • 10.1006/scdb.2000.0174 10966859
    • Easom RA Beta-granule transport and exocytosis Semin Cell Dev Biol 2000 11 4 253-266 10.1006/scdb.2000.0174 10966859
    • (2000) Semin Cell Dev Biol , vol.11 , Issue.4 , pp. 253-266
    • Easom, R.A.1
  • 63
    • 0036310678 scopus 로고    scopus 로고
    • A subset of 50 secretory granules in close contact with L-type Ca2+ channels accounts for first-phase insulin secretion in mouse beta-cells
    • 11815462
    • Barg S Eliasson L Renstrom E Rorsman P A subset of 50 secretory granules in close contact with L-type Ca2+ channels accounts for first-phase insulin secretion in mouse beta-cells Diabetes 2002 51 Suppl 1 S74-82 11815462
    • (2002) Diabetes , vol.51 , Issue.SUPPL. 1
    • Barg, S.1    Eliasson, L.2    Renstrom, E.3    Rorsman, P.4
  • 65
    • 0032545293 scopus 로고    scopus 로고
    • The changes in adenine nucleotides measured in glucose-stimulated rodent islets occur in beta cells but not in alpha cells and are also observed in human islets
    • 10.1074/jbc.273.51.33905 9852040
    • Detimary P Dejonghe S Ling Z Pipeleers D Schuit F Henquin JC The changes in adenine nucleotides measured in glucose-stimulated rodent islets occur in beta cells but not in alpha cells and are also observed in human islets J Biol Chem 1998 273 51 33905-33908 10.1074/ jbc.273.51.33905 9852040
    • (1998) J Biol Chem , vol.273 , Issue.51 , pp. 33905-33908
    • Detimary, P.1    Dejonghe, S.2    Ling, Z.3    Pipeleers, D.4    Schuit, F.5    Henquin, J.C.6
  • 66
    • 0035856942 scopus 로고    scopus 로고
    • Mitochondrial function in normal and diabetic beta-cells
    • 10.1038/414807a 11742413
    • Maechler P Wollheim CB Mitochondrial function in normal and diabetic beta-cells Nature 2001 414 6865 807-812 10.1038/414807a 11742413
    • (2001) Nature , vol.414 , Issue.6865 , pp. 807-812
    • Maechler, P.1    Wollheim, C.B.2
  • 68
    • 0036720536 scopus 로고    scopus 로고
    • Ion channels in secretory granules of the pancreas and their role in exocytosis and release of secretory proteins
    • 12176723
    • Thevenod F Ion channels in secretory granules of the pancreas and their role in exocytosis and release of secretory proteins Am J Physiol Cell Physiol 2002 283 3 C651-72 12176723
    • (2002) Am J Physiol Cell Physiol , vol.283 , Issue.3
    • Thevenod, F.1
  • 69
    • 0034500397 scopus 로고    scopus 로고
    • Translational regulation of proinsulin biosynthesis and proinsulin conversion in the pancreatic beta-cell
    • 10.1006/scdb.2000.0172 10966857
    • Goodge KA Hutton JC Translational regulation of proinsulin biosynthesis and proinsulin conversion in the pancreatic beta-cell Semin Cell Dev Biol 2000 11 4 235-242 10.1006/scdb.2000.0172 10966857
    • (2000) Semin Cell Dev Biol , vol.11 , Issue.4 , pp. 235-242
    • Goodge, K.A.1    Hutton, J.C.2
  • 70
    • 0025783174 scopus 로고
    • Glucose induces insulin gene transcription in a murine pancreatic beta-cell line
    • 1710218
    • Efrat S Surana M Fleischer N Glucose induces insulin gene transcription in a murine pancreatic beta-cell line J Biol Chem 1991 266 17 11141-11143 1710218
    • (1991) J Biol Chem , vol.266 , Issue.17 , pp. 11141-11143
    • Efrat, S.1    Surana, M.2    Fleischer, N.3
  • 71
    • 0022346359 scopus 로고
    • Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. II. Regulation of insulin mRNA stability
    • 3902821
    • Welsh M Nielsen DA MacKrell AJ Steiner DF Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. II. Regulation of insulin mRNA stability J Biol Chem 1985 260 25 13590-13594 3902821
    • (1985) J Biol Chem , vol.260 , Issue.25 , pp. 13590-13594
    • Welsh, M.1    Nielsen, D.A.2    MacKrell, A.J.3    Steiner, D.F.4
  • 72
    • 0028220203 scopus 로고
    • Insulin gene transcription is decreased rapidly by lowering glucose concentrations in rat islet cells
    • 8138056
    • Philippe J Pacheco I Meda P Insulin gene transcription is decreased rapidly by lowering glucose concentrations in rat islet cells Diabetes 1994 43 4 523-528 8138056
    • (1994) Diabetes , vol.43 , Issue.4 , pp. 523-528
    • Philippe, J.1    Pacheco, I.2    Meda, P.3
  • 73
    • 0020434553 scopus 로고
    • Direct effect of glucose on the preproinsulin mRNA level in isolated pancreatic islets
    • 10.1016/0006-291X(82)91267-0 7052089
    • Brunstedt J Chan SJ Direct effect of glucose on the preproinsulin mRNA level in isolated pancreatic islets Biochem Biophys Res Commun 1982 106 4 1383-1389 10.1016/0006-291X(82)91267-0 7052089
    • (1982) Biochem Biophys Res Commun , vol.106 , Issue.4 , pp. 1383-1389
    • Brunstedt, J.1    Chan, S.J.2
  • 74
    • 0035933884 scopus 로고    scopus 로고
    • Cooperativity between the preproinsulin mRNA untranslated regions is necessary for glucose-stimulated translation
    • 10.1074/jbc.M011214200 11297542
    • Wicksteed B Herbert TP Alarcon C Lingohr MK Moss LG Rhodes CJ Cooperativity between the preproinsulin mRNA untranslated regions is necessary for glucose-stimulated translation J Biol Chem 2001 276 25 22553-22558 10.1074/jbc.M011214200 11297542
    • (2001) J Biol Chem , vol.276 , Issue.25 , pp. 22553-22558
    • Wicksteed, B.1    Herbert, T.P.2    Alarcon, C.3    Lingohr, M.K.4    Moss, L.G.5    Rhodes, C.J.6
  • 75
    • 0036280885 scopus 로고    scopus 로고
    • A proinsulin gene splice variant with increased translation efficiency is expressed in human pancreatic islets
    • 10.1210/en.143.7.2541 12072386
    • Shalev A Blair PJ Hoffmann SC Hirshberg B Peculis BA Harlan DM A proinsulin gene splice variant with increased translation efficiency is expressed in human pancreatic islets Endocrinology 2002 143 7 2541-2547 10.1210/en.143.7.2541 12072386
    • (2002) Endocrinology , vol.143 , Issue.7 , pp. 2541-2547
    • Shalev, A.1    Blair, P.J.2    Hoffmann, S.C.3    Hirshberg, B.4    Peculis, B.A.5    Harlan, D.M.6
  • 76
    • 0037382747 scopus 로고    scopus 로고
    • Insulin does not mediate glucose stimulation of proinsulin biosynthesis
    • 12663472
    • Leibowitz G Oprescu AI Uckaya G Gross DJ Cerasi E Kaiser N Insulin does not mediate glucose stimulation of proinsulin biosynthesis Diabetes 2003 52 4 998-1003 12663472
    • (2003) Diabetes , vol.52 , Issue.4 , pp. 998-1003
    • Leibowitz, G.1    Oprescu, A.I.2    Uckaya, G.3    Gross, D.J.4    Cerasi, E.5    Kaiser, N.6
  • 77
    • 0142149134 scopus 로고    scopus 로고
    • Glucose-induced translational control of proinsulin biosynthesis is proportional to preproinsulin mRNA levels in islet beta-cells but not regulated via a positive feedback of secreted insulin
    • 10.1074/jbc.M303509200 12928442
    • Wicksteed B Alarcon C Briaud I Lingohr MK Rhodes CJ Glucose-induced translational control of proinsulin biosynthesis is proportional to preproinsulin mRNA levels in islet beta-cells but not regulated via a positive feedback of secreted insulin J Biol Chem 2003 278 43 42080-42090 10.1074/jbc.M303509200 12928442
    • (2003) J Biol Chem , vol.278 , Issue.43 , pp. 42080-42090
    • Wicksteed, B.1    Alarcon, C.2    Briaud, I.3    Lingohr, M.K.4    Rhodes, C.J.5
  • 79
    • 0030447883 scopus 로고    scopus 로고
    • Purification of the beta-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells
    • 26355 8986763 10.1073/pnas.93.26.15057
    • Marshak S Totary H Cerasi E Melloul D Purification of the beta-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells Proc Natl Acad Sci U S A 1996 93 26 15057-15062 26355 8986763 10.1073/pnas.93.26.15057
    • (1996) Proc Natl Acad Sci U S A , vol.93 , Issue.26 , pp. 15057-15062
    • Marshak, S.1    Totary, H.2    Cerasi, E.3    Melloul, D.4
  • 80
    • 0037076351 scopus 로고    scopus 로고
    • Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA
    • 124472 12011435 10.1073/pnas.102168499
    • Olbrot M Rud J Moss LG Sharma A Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA Proc Natl Acad Sci U S A 2002 99 10 6737-6742 124472 12011435 10.1073/ pnas.102168499
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.10 , pp. 6737-6742
    • Olbrot, M.1    Rud, J.2    Moss, L.G.3    Sharma, A.4
  • 81
    • 0041970072 scopus 로고    scopus 로고
    • Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells
    • 180917 12917329 10.1128/MCB.23.17.6049-6062.2003
    • Matsuoka TA Zhao L Artner I Jarrett HW Friedman D Means A Stein R Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells Mol Cell Biol 2003 23 17 6049-6062 180917 12917329 10.1128/MCB.23.17.6049-6062.2003
    • (2003) Mol Cell Biol , vol.23 , Issue.17 , pp. 6049-6062
    • Matsuoka, T.A.1    Zhao, L.2    Artner, I.3    Jarrett, H.W.4    Friedman, D.5    Means, A.6    Stein, R.7
  • 82
    • 0031943003 scopus 로고    scopus 로고
    • p300 mediates transcriptional stimulation by the basic helix-loop-helix activators of the insulin gene
    • 110675 9566915
    • Qiu Y Sharma A Stein R p300 mediates transcriptional stimulation by the basic helix-loop-helix activators of the insulin gene Mol Cell Biol 1998 18 5 2957-2964 110675 9566915
    • (1998) Mol Cell Biol , vol.18 , Issue.5 , pp. 2957-2964
    • Qiu, Y.1    Sharma, A.2    Stein, R.3
  • 83
    • 0037066726 scopus 로고    scopus 로고
    • Induction of c-Myc expression suppresses insulin gene transcription by inhibiting NeuroD/BETA2-mediated transcriptional activation
    • 10.1074/jbc.M111148200 11799123
    • Kaneto H Sharma A Suzuma K Laybutt DR Xu G Bonner-Weir S Weir GC Induction of c-Myc expression suppresses insulin gene transcription by inhibiting NeuroD/BETA2-mediated transcriptional activation J Biol Chem 2002 277 15 12998-13006 10.1074/jbc.M111148200 11799123
    • (2002) J Biol Chem , vol.277 , Issue.15 , pp. 12998-13006
    • Kaneto, H.1    Sharma, A.2    Suzuma, K.3    Laybutt, D.R.4    Xu, G.5    Bonner-Weir, S.6    Weir, G.C.7
  • 84
    • 0027154077 scopus 로고
    • Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters
    • 46406 8483904 10.1073/pnas.90.9.3865
    • Melloul D Ben-Neriah Y Cerasi E Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters Proc Natl Acad Sci U S A 1993 90 9 3865-3869 46406 8483904 10.1073/pnas.90.9.3865
    • (1993) Proc Natl Acad Sci U S A , vol.90 , Issue.9 , pp. 3865-3869
    • Melloul, D.1    Ben-Neriah, Y.2    Cerasi, E.3
  • 85
    • 0028808719 scopus 로고
    • The role of the insulin control element and RIPE3b1 activators in glucose-stimulated transcription of the insulin gene
    • 10.1210/me.9.11.1468 8584024
    • Sharma A Fusco-DeMane D Henderson E Efrat S Stein R The role of the insulin control element and RIPE3b1 activators in glucose-stimulated transcription of the insulin gene Mol Endocrinol 1995 9 11 1468-1476 10.1210/me.9.11.1468 8584024
    • (1995) Mol Endocrinol , vol.9 , Issue.11 , pp. 1468-1476
    • Sharma, A.1    Fusco-DeMane, D.2    Henderson, E.3    Efrat, S.4    Stein, R.5
  • 86
    • 22444443484 scopus 로고    scopus 로고
    • Synergistic activation of the insulin gene promoter by the beta-cell enriched transcription factors MafA, Beta2, and Pdx1
    • 15993959
    • Aramata S Han SI Yasuda K Kataoka K Synergistic activation of the insulin gene promoter by the beta-cell enriched transcription factors MafA, Beta2, and Pdx1 Biochim Biophys Acta 2005 1730 1 41-46 15993959
    • (2005) Biochim Biophys Acta , vol.1730 , Issue.1 , pp. 41-46
    • Aramata, S.1    Han, S.I.2    Yasuda, K.3    Kataoka, K.4
  • 87
    • 0034695492 scopus 로고    scopus 로고
    • Transcription factor BETA2 acts cooperatively with E2A and PDX1 to activate the insulin gene promoter
    • 10.1074/jbc.275.3.2199 10636926
    • Glick E Leshkowitz D Walker MD Transcription factor BETA2 acts cooperatively with E2A and PDX1 to activate the insulin gene promoter J Biol Chem 2000 275 3 2199-2204 10.1074/jbc.275.3.2199 10636926
    • (2000) J Biol Chem , vol.275 , Issue.3 , pp. 2199-2204
    • Glick, E.1    Leshkowitz, D.2    Walker, M.D.3
  • 88
    • 15744393397 scopus 로고    scopus 로고
    • The islet beta cell-enriched MafA activator is a key regulator of insulin gene transcription
    • 10.1074/jbc.M409475200 15665000
    • Zhao L Guo M Matsuoka TA Hagman DK Parazzoli SD Poitout V Stein R The islet beta cell-enriched MafA activator is a key regulator of insulin gene transcription J Biol Chem 2005 280 12 11887-11894 10.1074/ jbc.M409475200 15665000
    • (2005) J Biol Chem , vol.280 , Issue.12 , pp. 11887-11894
    • Zhao, L.1    Guo, M.2    Matsuoka, T.A.3    Hagman, D.K.4    Parazzoli, S.D.5    Poitout, V.6    Stein, R.7
  • 89
    • 25444480496 scopus 로고    scopus 로고
    • Palmitate inhibits insulin gene expression by altering PDX-1 nuclear localization and reducing MafA expression in isolated rat islets of Langerhans
    • 1361267 15944145 10.1074/jbc.M506000200
    • Hagman DK Hays LB Parazzoli SD Poitout V Palmitate inhibits insulin gene expression by altering PDX-1 nuclear localization and reducing MafA expression in isolated rat islets of Langerhans J Biol Chem 2005 280 37 32413-32418 1361267 15944145 10.1074/jbc.M506000200
    • (2005) J Biol Chem , vol.280 , Issue.37 , pp. 32413-32418
    • Hagman, D.K.1    Hays, L.B.2    Parazzoli, S.D.3    Poitout, V.4
  • 90
    • 4544233448 scopus 로고    scopus 로고
    • Glucose regulation of insulin gene expression requires the recruitment of p300 by the beta-cell-specific transcription factor Pdx-1
    • 10.1210/me.2003-0463 15166251
    • Mosley AL Corbett JA Ozcan S Glucose regulation of insulin gene expression requires the recruitment of p300 by the beta-cell-specific transcription factor Pdx-1 Mol Endocrinol 2004 18 9 2279-2290 10.1210/ me.2003-0463 15166251
    • (2004) Mol Endocrinol , vol.18 , Issue.9 , pp. 2279-2290
    • Mosley, A.L.1    Corbett, J.A.2    Ozcan, S.3
  • 91
    • 0036062438 scopus 로고    scopus 로고
    • PDX-1 mediates glucose responsiveness of GAD(67), but not GAD(65), gene transcription in islets of Langerhans
    • Pedersen AA, Petersen HV, Videbaek N, Skak K, Michelsen BK: PDX-1 mediates glucose responsiveness of GAD(67), but not GAD(65), gene transcription in islets of Langerhans. Biochem Biophys Res Commun 2002, 295(2):243-248.
    • (2002) Biochem Biophys Res Commun , vol.295 , Issue.2 , pp. 243-248
    • Pedersen, A.A.1    Petersen, H.V.2    Videbaek, N.3    Skak, K.4    Michelsen, B.K.5
  • 92
    • 0036210550 scopus 로고    scopus 로고
    • Regulation of insulin gene transcription
    • Melloul D, Marshak S, Cerasi E: Regulation of insulin gene transcription. Diabetologia 2002, 45(3):309-326.
    • (2002) Diabetologia , vol.45 , Issue.3 , pp. 309-326
    • Melloul, D.1    Marshak, S.2    Cerasi, E.3
  • 93
    • 0034530947 scopus 로고    scopus 로고
    • The PDX-1 activation domain provides specific functions necessary transcriptional stimulation in pancreatic beta-cells
    • Peshavaria M, Cissell MA, Henderson E, Petersen HV, Stein R: The PDX-1 activation domain provides specific functions necessary for transcriptional stimulation in pancreatic beta-cells. Mol Endocrinol 2000, 14(12):1907-1917.
    • (2000) Mol Endocrinol , vol.14 , Issue.12 , pp. 1907-1917
    • Peshavaria, M.1    Cissell, M.A.2    Henderson, E.3    Petersen, H.V.4    Stein, R.5
  • 94
    • 0033050114 scopus 로고    scopus 로고
    • Regulation of the insulin gene by glucose: Stimulation of trans-activation potency of human PDX-1 N-terminal domain DNA
    • Shushan EB, Cerasi E, Melloul D: Regulation of the insulin gene by glucose: Stimulation of trans-activation potency of human PDX-1 N-terminal domain. DNA Cell Biol 1999, 18(6):471-479.
    • (1999) Cell Biol , vol.18 , Issue.6 , pp. 471-479
    • Shushan, E.B.1    Cerasi, E.2    Melloul, D.3
  • 95
    • 0035489991 scopus 로고    scopus 로고
    • Phosphorylation-dependent nucleocytoplasmic shuttling of pancreatic duodenal homeobox-1
    • Elrick LJ, Docherty K: Phosphorylation-dependent nucleocytoplasmic shuttling of pancreatic duodenal homeobox-1. Diabetes 2001, 50(10):2244-2252.
    • (2001) Diabetes , vol.50 , Issue.10 , pp. 2244-2252
    • Elrick, L.J.1    Docherty, K.2
  • 96
    • 0034717337 scopus 로고    scopus 로고
    • Glucose-stimulated preproinsulin gene expression and nuclear trans-location of pancreatic duodenum homeobox-1 require activation of phosphatidylinositol 3-kinase but not p38 MAPK/SAPK2
    • Rafiq I, da Silva Xavier G, Hooper S, Rutter GA: Glucose-stimulated preproinsulin gene expression and nuclear trans-location of pancreatic duodenum homeobox-1 require activation of phosphatidylinositol 3-kinase but not p38 MAPK/SAPK2. J Biol Chem 2000, 275(21):15977-15984.
    • (2000) J Biol Chem , vol.275 , Issue.21 , pp. 15977-15984
    • Rafiq, I.1    da Silva Xavier, G.2    Hooper, S.3    Rutter, G.A.4
  • 97
    • 0032061042 scopus 로고    scopus 로고
    • Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/ PI-3 kinase/p70 s6 kinase and CaM kinase pathways
    • Leibiger IB, Leibiger B, Moede T, Berggren PO: Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/ PI-3 kinase/p70 s6 kinase and CaM kinase pathways. Mol Cell 1998, 1(6):933-938.
    • (1998) Mol Cell , vol.1 , Issue.6 , pp. 933-938
    • Leibiger, I.B.1    Leibiger, B.2    Moede, T.3    Berggren, P.O.4
  • 98
    • 0034610307 scopus 로고    scopus 로고
    • Insulin regulation of beta-cell function involves a feedback loop on SERCA gene expression, Ca(2+) homeostasis, and insulin expression and secretion
    • Xu GG, Gao ZY, Borge PD Jr., Jegier PA, Young RA, Wolf BA: Insulin regulation of beta-cell function involves a feedback loop on SERCA gene expression, Ca(2+) homeostasis, and insulin expression and secretion. Biochemistry 2000, 39(48):14912-14919.
    • (2000) Biochemistry , vol.39 , Issue.48 , pp. 14912-14919
    • Xu, G.G.1    Gao, Z.Y.2    Borge Jr., P.D.3    Jegier, P.A.4    Young, R.A.5    Wolf, B.A.6
  • 99
    • 0034730756 scopus 로고    scopus 로고
    • Glucose-stimulated insulin biosynthesis depends on insulin-stimulated insulin gene transcription
    • Leibiger B, Wahlander K, Berggren PO, Leibiger IB: Glucose-stimulated insulin biosynthesis depends on insulin-stimulated insulin gene transcription. J Biol Chem 2000, 275(39):30153-30156.
    • (2000) J Biol Chem , vol.275 , Issue.39 , pp. 30153-30156
    • Leibiger, B.1    Wahlander, K.2    Berggren, P.O.3    Leibiger, I.B.4
  • 100
    • 11144237178 scopus 로고    scopus 로고
    • The pancreatic duodenal homeobox-1 protein (Pdx-1) interacts with histone deacetylases Hdac-1 and Hdac-2 on low levels of glucose
    • Mosley AL, Ozcan S: The pancreatic duodenal homeobox-1 protein (Pdx-1) interacts with histone deacetylases Hdac-1 and Hdac-2 on low levels of glucose. J Biol Chem 2004, 279(52):54241-54247.
    • (2004) J Biol Chem , vol.279 , Issue.52 , pp. 54241-54247
    • Mosley, A.L.1    Ozcan, S.2
  • 101
    • 0028941181 scopus 로고
    • Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor
    • Naya FJ, Stellrecht CM, Tsai MJ: Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor. Genes Dev 1995, 9(8):1009-1019.
    • (1995) Genes Dev , vol.9 , Issue.8 , pp. 1009-1019
    • Naya, F.J.1    Stellrecht, C.M.2    Tsai, M.J.3
  • 102
    • 0030070145 scopus 로고    scopus 로고
    • Function of the human insulin promoter in primary cultured islet cells
    • Odagiri H, Wang J, German MS: Function of the human insulin promoter in primary cultured islet cells. J Biol Chem 1996, 271(4):1909-1915.
    • (1996) J Biol Chem , vol.271 , Issue.4 , pp. 1909-1915
    • Odagiri, H.1    Wang, J.2    German, M.S.3
  • 104
    • 0041856361 scopus 로고    scopus 로고
    • Regulation of insulin gene transcription by ERK1 and ERK2 in pancreatic beta cells
    • Khoo S, Griffen SC, Xia Y, Baer RJ, German MS, Cobb MH: Regulation of insulin gene transcription by ERK1 and ERK2 in pancreatic beta cells. J Biol Chem 2003, 278(35):32969-32977.
    • (2003) J Biol Chem , vol.278 , Issue.35 , pp. 32969-32977
    • Khoo, S.1    Griffen, S.C.2    Xia, Y.3    Baer, R.J.4    German, M.S.5    Cobb, M.H.6
  • 105
    • 22844446279 scopus 로고    scopus 로고
    • ERK1/2-dependent activation of transcription factors required for acute and chronic effects of glucose on the insulin gene promoter
    • Lawrence MC, McGlynn K, Park BH, Cobb MH: ERK1/2-dependent activation of transcription factors required for acute and chronic effects of glucose on the insulin gene promoter. J Biol Chem 2005, 280(29):26751-26759.
    • (2005) J Biol Chem , vol.280 , Issue.29 , pp. 26751-26759
    • Lawrence, M.C.1    McGlynn, K.2    Park, B.H.3    Cobb, M.H.4
  • 106
    • 0031656888 scopus 로고    scopus 로고
    • Glucose and glucoincretin peptides synergize to induce c-fos, c-jun, junB, zif-268, and nur-77 gene expression in pancreatic beta(INS-1) cells
    • Susini S, Roche E, Prentki M, Schlegel W: Glucose and glucoincretin peptides synergize to induce c-fos, c-jun, junB, zif-268, and nur-77 gene expression in pancreatic beta(INS-1) cells. Faseb J 1998, 12(12):1173-1182.
    • (1998) Faseb J , vol.12 , Issue.12 , pp. 1173-1182
    • Susini, S.1    Roche, E.2    Prentki, M.3    Schlegel, W.4
  • 107
    • 0032955739 scopus 로고    scopus 로고
    • Glucose induces early growth response gene (Egr-1) expression in pancreatic beta cells
    • Josefsen K, Sorensen LR, Buschard K, Birkenbach M: Glucose induces early growth response gene (Egr-1) expression in pancreatic beta cells. Diabetologia 1999, 42(2):195-203.
    • (1999) Diabetologia , vol.42 , Issue.2 , pp. 195-203
    • Josefsen, K.1    Sorensen, L.R.2    Buschard, K.3    Birkenbach, M.4
  • 108
    • 0036721124 scopus 로고    scopus 로고
    • Glucose-regulated proinsulin gene expression is required for adequate insulin production during chronic glucose exposure
    • Leibowitz G, Uckaya G, Oprescu AI, Cerasi E, Gross DJ, Kaiser N: Glucose-regulated proinsulin gene expression is required for adequate insulin production during chronic glucose exposure. Endocrinology 2002, 143(9):3214-3220.
    • (2002) Endocrinology , vol.143 , Issue.9 , pp. 3214-3220
    • Leibowitz, G.1    Uckaya, G.2    Oprescu, A.I.3    Cerasi, E.4    Gross, D.J.5    Kaiser, N.6
  • 110
    • 0039829851 scopus 로고
    • Glucose stimulates proinsulin biosynthesis by a dose-dependent recruitment of pancreatic beta cells
    • Schuit FC, In't Veld PA, Pipeleers DG: Glucose stimulates proinsulin biosynthesis by a dose-dependent recruitment of pancreatic beta cells. Proc Natl Acad Sci U S A 1988, 85(11):3865-3869.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , Issue.11 , pp. 3865-3869
    • Schuit, F.C.1    In't Veld, P.A.2    Pipeleers, D.G.3
  • 111
    • 0030028173 scopus 로고    scopus 로고
    • Glucose stimulates the activity of the guanine nucleotide-exchange factor eIF-2B in isolated rat islets of Langerhans
    • Gilligan M, Welsh GI, Flynn A, Bujalska I, Diggle TA, Denton RM, Proud CG, Docherty K: Glucose stimulates the activity of the guanine nucleotide-exchange factor eIF-2B in isolated rat islets of Langerhans. J Biol Chem 1996, 271(4):2121-2125.
    • (1996) J Biol Chem , vol.271 , Issue.4 , pp. 2121-2125
    • Gilligan, M.1    Welsh, G.I.2    Flynn, A.3    Bujalska, I.4    Diggle, T.A.5    Denton, R.M.6    Proud, C.G.7    Docherty, K.8
  • 112
    • 0037705347 scopus 로고    scopus 로고
    • Glucose regulates EF-2 phosphorylation and protein translation by a protein phosphatase-2A-dependent mechanism in INS-1-derived 832/13 cells
    • Yan L, Nairn AC, Palfrey HC, Brady MJ: Glucose regulates EF-2 phosphorylation and protein translation by a protein phosphatase-2A-dependent mechanism in INS-1-derived 832/13 cells. J Biol Chem 2003, 278(20):18177-18183.
    • (2003) J Biol Chem , vol.278 , Issue.20 , pp. 18177-18183
    • Yan, L.1    Nairn, A.C.2    Palfrey, H.C.3    Brady, M.J.4
  • 113
    • 0032548831 scopus 로고    scopus 로고
    • Insulin mediates glucose-stimulated phosphorylation of PHAS-I by pancreatic beta cells. An insulin-receptor mechanism for autoregulation of protein synthesis by translation
    • Xu G, Marshall CA, Lin TA, Kwon G, Munivenkatappa RB, Hill JR, Lawrence JC Jr., McDaniel ML: Insulin mediates glucose-stimulated phosphorylation of PHAS-I by pancreatic beta cells. An insulin-receptor mechanism for autoregulation of protein synthesis by translation. J Biol Chem 1998, 273(8):4485-4491.
    • (1998) J Biol Chem , vol.273 , Issue.8 , pp. 4485-4491
    • Xu, G.1    Marshall, C.A.2    Lin, T.A.3    Kwon, G.4    Munivenkatappa, R.B.5    Hill, J.R.6    Lawrence Jr., J.C.7    McDaniel, M.L.8
  • 114
    • 11144222577 scopus 로고    scopus 로고
    • Glucose-stimulated protein synthesis in pancreatic beta-cells parallels an increase in the availability of the translational ternary complex (eIF2-GTP.Met-tRNAi) and the dephosphorylation of eIF2 alpha
    • Gomez E, Powell ML, Greenman IC, Herbert TP: Glucose-stimulated protein synthesis in pancreatic beta-cells parallels an increase in the availability of the translational ternary complex (eIF2-GTP.Met-tRNAi) and the dephosphorylation of eIF2 alpha. J Biol Chem 2004, 279(52):53937-53946.
    • (2004) J Biol Chem , vol.279 , Issue.52 , pp. 53937-53946
    • Gomez, E.1    Powell, M.L.2    Greenman, I.C.3    Herbert, T.P.4
  • 115
    • 0022380579 scopus 로고
    • Control of insulin gene expression in pancreatic beta-cells and in an insulinproducing cell line, RIN-5F cells. I. Effects of glucose and cyclic AMP on the transcription of insulin mRNA
    • Nielsen DA, Welsh M, Casadaban MJ, Steiner DF: Control of insulin gene expression in pancreatic beta-cells and in an insulinproducing cell line, RIN-5F cells. I. Effects of glucose and cyclic AMP on the transcription of insulin mRNA. J Biol Chem 1985, 260(25):13585-13589.
    • (1985) J Biol Chem , vol.260 , Issue.25 , pp. 13585-13589
    • Nielsen, D.A.1    Welsh, M.2    Casadaban, M.J.3    Steiner, D.F.4
  • 116
  • 117
    • 0027199057 scopus 로고
    • Glucose regulates acetyl-CoA carboxylase gene expression in a pancreatic beta-cell line (INS-1)
    • Brun T, Roche E, Kim KH, Prentki M: Glucose regulates acetyl-CoA carboxylase gene expression in a pancreatic beta-cell line (INS-1). J Biol Chem 1993, 268(25):18905-18911.
    • (1993) J Biol Chem , vol.268 , Issue.25 , pp. 18905-18911
    • Brun, T.1    Roche, E.2    Kim, K.H.3    Prentki, M.4
  • 118
    • 0027436399 scopus 로고
    • The pyruvate kinase gene as a model for studies of glucosedependent regulation of gene expression in the endocrine pancreatic beta-cell type
    • Marie S, Diaz-Guerra MJ, Miquerol L, Kahn A, Iynedjian PB: The pyruvate kinase gene as a model for studies of glucosedependent regulation of gene expression in the endocrine pancreatic beta-cell type. J Biol Chem 1993, 268(32):23881-23890.
    • (1993) J Biol Chem , vol.268 , Issue.32 , pp. 23881-23890
    • Marie, S.1    Diaz-Guerra, M.J.2    Miquerol, L.3    Kahn, A.4    Iynedjian, P.B.5
  • 119
    • 8644277274 scopus 로고    scopus 로고
    • Adult pancreas generates multipotent stem cells and pancreatic and nonpancreatic progeny
    • Choi Y, Ta M, Atouf F, Lumelsky N: Adult pancreas generates multipotent stem cells and pancreatic and nonpancreatic progeny. Stem Cells 2004, 22:1070-1084.
    • (2004) Stem Cells , vol.22 , pp. 1070-1084
    • Choi, Y.1    Ta, M.2    Atouf, F.3    Lumelsky, N.4


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