-
1
-
-
0028960739
-
Structure of the human gene encoding sterol regulatory element binding protein-1 (SREBF1) and localization of SREBF1 and SREBF2 to chromosomes 17p11.2 and 22q13
-
Hua X, Wu J, Goldstein JL, Brown MS, Hobbs HH: Structure of the human gene encoding sterol regulatory element binding protein-1 (SREBF1) and localization of SREBF1 and SREBF2 to chromosomes 17p11.2 and 22q13. Genomics 25:667-673, 1995
-
(1995)
Genomics
, vol.25
, pp. 667-673
-
-
Hua, X.1
Wu, J.2
Goldstein, J.L.3
Brown, M.S.4
Hobbs, H.H.5
-
2
-
-
0036251153
-
SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
-
Horton JD, Goldstein JL, Brown MS: SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest 109:1125-1131, 2002
-
(2002)
J Clin Invest
, vol.109
, pp. 1125-1131
-
-
Horton, J.D.1
Goldstein, J.L.2
Brown, M.S.3
-
3
-
-
0030961960
-
Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells
-
Shimomura I, Shimano H, Horton JD, Goldstein JL, Brown MS: Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells. J Clin Invest 99:838-845, 1997
-
(1997)
J Clin Invest
, vol.99
, pp. 838-845
-
-
Shimomura, I.1
Shimano, H.2
Horton, J.D.3
Goldstein, J.L.4
Brown, M.S.5
-
4
-
-
0035029812
-
Regulation by insulin of gene expression in human skeletal muscle and adipose tissue: Evidence for specific defects in type 2 diabetes
-
Ducluzeau PH, Perretti N, Laville M, Andreelli F, Vega N, Riou JP, Vidal H: Regulation by insulin of gene expression in human skeletal muscle and adipose tissue: evidence for specific defects in type 2 diabetes. Diabetes 50:1134-1142, 2001
-
(2001)
Diabetes
, vol.50
, pp. 1134-1142
-
-
Ducluzeau, P.H.1
Perretti, N.2
Laville, M.3
Andreelli, F.4
Vega, N.5
Riou, J.P.6
Vidal, H.7
-
5
-
-
0036259860
-
Sterol regulatory element binding protein-1c expression and action in rat muscles: Insulin-like effects on the control of glycolytic and lipogenic enzymes and UCP3 gene expression
-
Guillet-Deniau I, Mieulet V, Le Lay S, Achouri Y, Carre D, Girard J, Foufelle F, Ferre P: Sterol regulatory element binding protein-1c expression and action in rat muscles: insulin-like effects on the control of glycolytic and lipogenic enzymes and UCP3 gene expression. Diabetes 51:1722-1728, 2002
-
(2002)
Diabetes
, vol.51
, pp. 1722-1728
-
-
Guillet-Deniau, I.1
Mieulet, V.2
Le Lay, S.3
Achouri, Y.4
Carre, D.5
Girard, J.6
Foufelle, F.7
Ferre, P.8
-
6
-
-
0033607176
-
Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes
-
Foretz M, Guichard C, Ferre P, Foufelle F: Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes. Proc Natl Acad Sci USA 96:12737-12742, 1999
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 12737-12742
-
-
Foretz, M.1
Guichard, C.2
Ferre, P.3
Foufelle, F.4
-
7
-
-
0036228456
-
Human obesity and type 2 diabetes are associated with alterations in SREBP1 isoform expression that are reproduced ex vivo by tumor necrosis factor-α
-
Sewter C, Berger D, Considine RV, Medina G, Rochford J, Ciaraldi T, Henry R, Dohm L, Flier JS, O'Rahilly S, Vidal-Puig AJ: Human obesity and type 2 diabetes are associated with alterations in SREBP1 isoform expression that are reproduced ex vivo by tumor necrosis factor-α. Diabetes 51:1035-1041, 2002
-
(2002)
Diabetes
, vol.51
, pp. 1035-1041
-
-
Sewter, C.1
Berger, D.2
Considine, R.V.3
Medina, G.4
Rochford, J.5
Ciaraldi, T.6
Henry, R.7
Dohm, L.8
Flier, J.S.9
O'Rahilly, S.10
Vidal-Puig, A.J.11
-
8
-
-
0037088683
-
Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c
-
Liang G, Yang J, Horton JD, Hammer RE, Goldstein JL, Brown MS: Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c. J Biol Chem 277:9520-9528, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 9520-9528
-
-
Liang, G.1
Yang, J.2
Horton, J.D.3
Hammer, R.E.4
Goldstein, J.L.5
Brown, M.S.6
-
9
-
-
0033749620
-
Signalling aspects of insulin resistance in skeletal muscle: Mechanisms induced by lipid oversupply
-
Schmitz-Peiffer C: Signalling aspects of insulin resistance in skeletal muscle: mechanisms induced by lipid oversupply. Cell Signal 12:583-594, 2000
-
(2000)
Cell Signal
, vol.12
, pp. 583-594
-
-
Schmitz-Peiffer, C.1
-
10
-
-
0033570119
-
Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus
-
Shimomura I, Bashmakov Y, Horton JD: Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus. J Biol Chem 274:30028-30032, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 30028-30032
-
-
Shimomura, I.1
Bashmakov, Y.2
Horton, J.D.3
-
11
-
-
10744230909
-
A meta-analysis of four European genome screens (GIFT Consortium) shows evidence for a novel region on chromosome 17p11.2-q22 linked to type 2 diabetes
-
Demenais F, Kanninen T, Lindgren CM, Wiltshire S, Gaget S, Dandrieux C, Almgren P, Sjogren M, Hattersley A, Dina C, Tuomi T, McCarthy MI, Froguel P, Groop LC: A meta-analysis of four European genome screens (GIFT Consortium) shows evidence for a novel region on chromosome 17p11.2-q22 linked to type 2 diabetes. Hum Mol Genet 12:1865-1873, 2003
-
(2003)
Hum Mol Genet
, vol.12
, pp. 1865-1873
-
-
Demenais, F.1
Kanninen, T.2
Lindgren, C.M.3
Wiltshire, S.4
Gaget, S.5
Dandrieux, C.6
Almgren, P.7
Sjogren, M.8
Hattersley, A.9
Dina, C.10
Tuomi, T.11
McCarthy, M.I.12
Froguel, P.13
Groop, L.C.14
-
12
-
-
3242809742
-
SREBF-1 gene polymorphisms are associated with obesity and type 2 diabetes in French obese and diabetic cohorts
-
Eberlé D, Clément K, Meyre D, Sahbatou M, Vaxillaire M, Le Gall A, Ferré P, Basdevant A, Froguel P, Foufelle F: SREBF-1 gene polymorphisms are associated with obesity and type 2 diabetes in French obese and diabetic cohorts. Diabetes 53:2153-2157, 2004
-
(2004)
Diabetes
, vol.53
, pp. 2153-2157
-
-
Eberlé, D.1
Clément, K.2
Meyre, D.3
Sahbatou, M.4
Vaxillaire, M.5
Le Gall, A.6
Ferré, P.7
Basdevant, A.8
Froguel, P.9
Foufelle, F.10
-
13
-
-
10744222217
-
Genetic variants in human sterol regulatory element binding protein-1c in syndromes of severe insulin resistance and type 2 diabetes
-
Laudes M, Barroso I, Luan J, Soos MA, Yeo G, Meirhaeghe A, Logie L, Vidal-Puig A, Schafer AJ, Wareham NJ, O'Rahilly S: Genetic variants in human sterol regulatory element binding protein-1c in syndromes of severe insulin resistance and type 2 diabetes. Diabetes 53:842-846, 2004
-
(2004)
Diabetes
, vol.53
, pp. 842-846
-
-
Laudes, M.1
Barroso, I.2
Luan, J.3
Soos, M.A.4
Yeo, G.5
Meirhaeghe, A.6
Logie, L.7
Vidal-Puig, A.8
Schafer, A.J.9
Wareham, N.J.10
O'Rahilly, S.11
-
14
-
-
33749851823
-
Polymorphisms in the gene encoding sterol regulatory element-binding factor-1c are associated with type 2 diabetes
-
Harding AH, Loos RJ, Luan J, O'Rahilly S, Wareham NJ, Barroso I: Polymorphisms in the gene encoding sterol regulatory element-binding factor-1c are associated with type 2 diabetes. Diabetologia 49:2642-2648.
-
Diabetologia
, vol.49
, pp. 2642-2648
-
-
Harding, A.H.1
Loos, R.J.2
Luan, J.3
O'Rahilly, S.4
Wareham, N.J.5
Barroso, I.6
-
15
-
-
64549106230
-
-
2006
-
2006
-
-
-
-
16
-
-
34250888726
-
The SREBF-1 locus is associated with type 2 diabetes and plasma adiponectin levels in a middle-aged Austrian population
-
Felder TK, Oberkofler H, Weitgasser R, Mackevics V, Krempler F, Paulwe-ber B, Patsch W: The SREBF-1 locus is associated with type 2 diabetes and plasma adiponectin levels in a middle-aged Austrian population. Int J Obes (Lond) 31:1099-1103, 2007
-
(2007)
Int J Obes (Lond)
, vol.31
, pp. 1099-1103
-
-
Felder, T.K.1
Oberkofler, H.2
Weitgasser, R.3
Mackevics, V.4
Krempler, F.5
Paulwe-ber, B.6
Patsch, W.7
-
17
-
-
33847176604
-
A genome-wide association study identifies novel risk loci for type 2 diabetes
-
Sladek R, Rocheleau G, Rung J, Dina C, Shen L, Serre D, Boutin P, Vincent D, Belisle A, Hadjadj S, Balkau B, Heude B, Charpentier G, Hudson TJ, Montpetit A, Pshezhetsky AV, Prentki M, Posner BI, Balding DJ, Meyre D, Polychronakos C, Froguel P: A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 445:881-885, 2007
-
(2007)
Nature
, vol.445
, pp. 881-885
-
-
Sladek, R.1
Rocheleau, G.2
Rung, J.3
Dina, C.4
Shen, L.5
Serre, D.6
Boutin, P.7
Vincent, D.8
Belisle, A.9
Hadjadj, S.10
Balkau, B.11
Heude, B.12
Charpentier, G.13
Hudson, T.J.14
Montpetit, A.15
Pshezhetsky, A.V.16
Prentki, M.17
Posner, B.I.18
Balding, D.J.19
Meyre, D.20
Polychronakos, C.21
Froguel, P.22
more..
-
18
-
-
34249828965
-
-
Steinthorsdottir V, Thorleifsson G, Reynisdottir I, Benediktsson R, Jonsdottir T, Walters GB, Styrkarsdottir U, Gretarsdottir S, Emilsson V, Ghosh S, Baker A, Snorradottir S, Bjarnason H, Ng MCY, Hansen T, Bagger Y, Wilensky RL, Reilly MP, Adeyemo A, Chen Y, Zhou J, Gudnason V, Chen G, Huang H, Lashley K, Doumatey A, So WY, Ma RCY, Andersen G, Borch-Johnsen K, Jorgensen T, Vliet-Ostaptchouk JV, Hofker MH, Wij-menga C, Christiansen C, Rader DJ, Rotimi C, Gurney M, Chan JCN, Pedersen O, Sigurdsson G, Gulcher JR, Thorsteinsdottir U, Kong A, Stefansson K: A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet 39:770-775, 2007
-
Steinthorsdottir V, Thorleifsson G, Reynisdottir I, Benediktsson R, Jonsdottir T, Walters GB, Styrkarsdottir U, Gretarsdottir S, Emilsson V, Ghosh S, Baker A, Snorradottir S, Bjarnason H, Ng MCY, Hansen T, Bagger Y, Wilensky RL, Reilly MP, Adeyemo A, Chen Y, Zhou J, Gudnason V, Chen G, Huang H, Lashley K, Doumatey A, So WY, Ma RCY, Andersen G, Borch-Johnsen K, Jorgensen T, Vliet-Ostaptchouk JV, Hofker MH, Wij-menga C, Christiansen C, Rader DJ, Rotimi C, Gurney M, Chan JCN, Pedersen O, Sigurdsson G, Gulcher JR, Thorsteinsdottir U, Kong A, Stefansson K: A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet 39:770-775, 2007
-
-
-
-
19
-
-
34249888775
-
-
Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, and Novartis Institutes of BioMedical Research; Saxena R, Voight BF, Lyssenko V, Burtt NP, de Bakker PIW, Chen H, Roix JJ, Kathiresan S, Hirschhorn JN, Daly MJ, Hughes TE, Groop L, Altshuler D, Almgren P, Florez JC, Meyer J, Ardlie K, Bengtsson Bostrom K, Isomaa B, Lettre G, Lindblad U, Lyon HN, Melander O, Newton-Cheh C, Nilsson P, Orho-Melander M, Rastam L, Speliotes EK, Taskinen MR, Tuomi T, Guiducci C, Berglund A, Carlson J, Gianniny L, Hackett R, Hall L, Holmkvist J, Laurila E, Sjogren M, Sterner M, Surti A, Svensson M, Svensson M, Tewhey R, Blumenstiel B, Parkin M, DeFelice M, Barry R, Brodeur W, Camarata J, Chia N, Fava M, Gibbons J, Handsaker B, Healy C, Nguyen K, Gates C, Sougnez C, Gage D, Nizzari M, Gabriel SB, Chirn GW, Ma Q, Parikh H, Richardson D, Ricke D, Purcell S: Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 316:1331-1336
-
Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, and Novartis Institutes of BioMedical Research; Saxena R, Voight BF, Lyssenko V, Burtt NP, de Bakker PIW, Chen H, Roix JJ, Kathiresan S, Hirschhorn JN, Daly MJ, Hughes TE, Groop L, Altshuler D, Almgren P, Florez JC, Meyer J, Ardlie K, Bengtsson Bostrom K, Isomaa B, Lettre G, Lindblad U, Lyon HN, Melander O, Newton-Cheh C, Nilsson P, Orho-Melander M, Rastam L, Speliotes EK, Taskinen MR, Tuomi T, Guiducci C, Berglund A, Carlson J, Gianniny L, Hackett R, Hall L, Holmkvist J, Laurila E, Sjogren M, Sterner M, Surti A, Svensson M, Svensson M, Tewhey R, Blumenstiel B, Parkin M, DeFelice M, Barry R, Brodeur W, Camarata J, Chia N, Fava M, Gibbons J, Handsaker B, Healy C, Nguyen K, Gates C, Sougnez C, Gage D, Nizzari M, Gabriel SB, Chirn GW, Ma Q, Parikh H, Richardson D, Ricke D, Purcell S: Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 316:1331-1336, 2007
-
-
-
-
20
-
-
34249895023
-
-
Zeggini E, Weedon MN, Lindgren CM, Frayling TM, Elliott KS, Lango H, Timpson NJ, Perry JRB, Rayner NW, Freathy RM, Barrett JC, Shields B, Morris AP, Ellard S, Groves CJ, Harries LW, Marchini JL, Owen KR, Knight B, Cardon LR, Walker M, Hitman GA, Morris AD, Doney ASF, The Wellcome Trust Case Control Consortium, McCarthy MI, Hattersley AT: Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 316:1336-1341, 2007
-
Zeggini E, Weedon MN, Lindgren CM, Frayling TM, Elliott KS, Lango H, Timpson NJ, Perry JRB, Rayner NW, Freathy RM, Barrett JC, Shields B, Morris AP, Ellard S, Groves CJ, Harries LW, Marchini JL, Owen KR, Knight B, Cardon LR, Walker M, Hitman GA, Morris AD, Doney ASF, The Wellcome Trust Case Control Consortium, McCarthy MI, Hattersley AT: Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 316:1336-1341, 2007
-
-
-
-
21
-
-
34249885875
-
-
Scott LJ, Mohlke KL, Bonnycastle LL, Willer CJ, Li Y, Duren WL, Erdos MR, Stringham HM, Chines PS, Jackson AU, Prokunina-Olsson L, Ding CJ, Swift AJ, Narisu N, Hu T, Pruim R, Xiao R, Li XY, Conneely KN, Riebow NL, Sprau AG, Tong M, White PP, Hetrick KN, Barnhart MW, Bark CW, Goldstein JL, Watkins L, Xiang F, Saramies J, Buchanan TA, Watanabe RM, Valle TT, Kinnunen L, Abecasis GR, Pugh EW, Doheny KF, Bergman RN, Tuomilehto J, Collins FS, Boehnke M: A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 316:1341-1345, 2007
-
Scott LJ, Mohlke KL, Bonnycastle LL, Willer CJ, Li Y, Duren WL, Erdos MR, Stringham HM, Chines PS, Jackson AU, Prokunina-Olsson L, Ding CJ, Swift AJ, Narisu N, Hu T, Pruim R, Xiao R, Li XY, Conneely KN, Riebow NL, Sprau AG, Tong M, White PP, Hetrick KN, Barnhart MW, Bark CW, Goldstein JL, Watkins L, Xiang F, Saramies J, Buchanan TA, Watanabe RM, Valle TT, Kinnunen L, Abecasis GR, Pugh EW, Doheny KF, Bergman RN, Tuomilehto J, Collins FS, Boehnke M: A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 316:1341-1345, 2007
-
-
-
-
22
-
-
0346394178
-
-
J0rgensen T, Borch-Johnsen K, Thomsen TF, Ibsen H, Glumer C, Pisinger C: A randomized non-pharmacological intervention study for prevention of ischaemic heart disease: Baseline results Inter99 (1). Eur J Cardiovasc Prev Rehab 10:377-386, 2003
-
J0rgensen T, Borch-Johnsen K, Thomsen TF, Ibsen H, Glumer C, Pisinger C: A randomized non-pharmacological intervention study for prevention of ischaemic heart disease: Baseline results Inter99 (1). Eur J Cardiovasc Prev Rehab 10:377-386, 2003
-
-
-
-
23
-
-
0033808127
-
The ADDITION study: Proposed trial of the cost-effectiveness of an intensive multifactorial intervention on morbidity and mortality among people with type 2 diabetes detected by screening
-
for the ADDITION Study Group
-
Lauritzen T, Griffin S, Borch-Johnsen K, Wareham NJ, Wolffenbuttel BH, Rutten G, for the ADDITION Study Group: The ADDITION study: proposed trial of the cost-effectiveness of an intensive multifactorial intervention on morbidity and mortality among people with type 2 diabetes detected by screening. Int J Obes Relat Metab Disord 24 (Suppl. 3):S6-S11, 2000
-
(2000)
Int J Obes Relat Metab Disord
, vol.24
, Issue.SUPPL. 3
-
-
Lauritzen, T.1
Griffin, S.2
Borch-Johnsen, K.3
Wareham, N.J.4
Wolffenbuttel, B.H.5
Rutten, G.6
-
24
-
-
0003725206
-
Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications
-
World Health Organization Study Group:, Geneva, World Health Org
-
World Health Organization Study Group: Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications. Part 1. Diagnosis and Classification of Diabetes Mellitus. Geneva, World Health Org., 1999
-
(1999)
Diagnosis and Classification of Diabetes Mellitus
, Issue.PART 1
-
-
-
25
-
-
64549145153
-
-
Carlson CS, Eberle MA, Rieder MJ, Yi Q, Kruglyak L, Nickerson DA
-
Carlson CS, Eberle MA, Rieder MJ, Yi Q, Kruglyak L, Nickerson DA:
-
-
-
-
26
-
-
0346373654
-
-
Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. Am J Hum Genet 74:106-120, 2004
-
Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. Am J Hum Genet 74:106-120, 2004
-
-
-
-
27
-
-
0041672374
-
Estimation and tests of haplotype-environment interaction when linkage phase is ambiguous
-
Lake SL, Lyon H, Tantisira K, Silverman EK, Weiss ST, Laird NM, Schaid DJ: Estimation and tests of haplotype-environment interaction when linkage phase is ambiguous. Hum Hered 55:56-65, 2003
-
(2003)
Hum Hered
, vol.55
, pp. 56-65
-
-
Lake, S.L.1
Lyon, H.2
Tantisira, K.3
Silverman, E.K.4
Weiss, S.T.5
Laird, N.M.6
Schaid, D.J.7
-
28
-
-
33846821782
-
The BIGTT test: A novel test for simultaneous measurement of pancreatic β-cell function, insulin sensitivity, and glucose tolerance
-
Hansen T, Drivsholm T, Urhammer SA, Palacios RT, Vølund A, Borch-Johnsen K, Pedersen O: The BIGTT test: a novel test for simultaneous measurement of pancreatic β-cell function, insulin sensitivity, and glucose tolerance. Diabetes Care 30:257-262, 2007
-
(2007)
Diabetes Care
, vol.30
, pp. 257-262
-
-
Hansen, T.1
Drivsholm, T.2
Urhammer, S.A.3
Palacios, R.T.4
Vølund, A.5
Borch-Johnsen, K.6
Pedersen, O.7
|