The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes

Diabetes

Volumn 52, Issue 2, 2003, Pages 573-577

  Nielsen, Eva Maria D ^a   Hansen, Lars ^a,b   Carstensen, Bendix ^a   Echwald, Søren M ^a   Drivsholm, Thomas ^c   Glümer, Charlotte ^a   Thorsteinsson, Birger ^d   Borch Johnsen, Knut ^a   Hansen, Torben ^a   Pedersen, Oluf ^a,e  

^a STENO DIABETES CENTER   (Denmark)

^b NOVO NORDISK A S   (Denmark)

^c GLOSTRUP UNIVERSITY HOSPITAL   (Denmark)

^d HILLERØD HOSPITAL   (Denmark)

^e AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; GLUCOSE; INSULIN; MEMBRANE PROTEIN; POTASSIUM CHANNEL; PROTEIN KIR6.2; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; BODY MASS; CAUCASIAN; CONTROLLED STUDY; DIABETOGENESIS; DISEASE ASSOCIATION; FEMALE; GENETIC VARIABILITY; GENOTYPE; GLUCOSE TOLERANCE TEST; HUMAN; IMPAIRED GLUCOSE TOLERANCE; IN VITRO STUDY; INSULIN BLOOD LEVEL; INSULIN METABOLISM; INSULIN RELEASE; INSULIN RESPONSE; INSULIN SYNTHESIS; KCNJ11 GENE; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN VARIANT; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

AMINO ACID SUBSTITUTION; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; GENOTYPE; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RISK FACTORS; VARIATION (GENETICS);

EID: 0037312864     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.52.2.573     Document Type: Article

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