Revisiting the Clinical Validity of Multiplex Genetic Testing in Complex Diseases [2]

American Journal of Human Genetics

Volumn 74, Issue 3, 2004, Pages 585-588

  Janssens, A Cecile J W ^a   Pardo, M Carolina ^a   Steyerberg, Ewout W ^a   Van Duijn, Cornelia M ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DEEP VEIN THROMBOSIS; DIAGNOSTIC VALUE; GENETIC ANALYSIS; HUMAN; LETTER; MULTIFACTORIAL GENETIC DISORDER; PENETRANCE; PREVALENCE; PRIORITY JOURNAL; PROBABILITY; ROC CURVE; STATISTICAL MODEL; VALIDATION PROCESS;

EID: 1542314297     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/382052     Document Type: Letter

References (6)

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2. Hanley JA, McNeil BJ (1982) The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology 143:29-36
3. Holtzman NA, Marteau TM (2000) Will genetics revolutionize medicine? N Engl J Med 343:141-144
4. Thompson ML, Zucchini W (1989) On the statistical analysis of ROC curves. Stat Med 8:1277-1290
5. Vineis P, Schulte P, McMichael AJ (2001) Misconceptions about the use of genetic tests in populations. Lancet 357: 709-712
6. Yang Q, Khoury MJ, Botto L, Friedman JM, Flanders WD (2003) Improving the prediction of complex diseases by testing for multiple disease-susceptibility genes. Am J Hum Genet 72:636-649