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Volumn 314, Issue 1, 2012, Pages 24-33

Inflammasomes as molecular mediators of inflammation and cancer: Potential role in melanoma

Author keywords

ASC; Cancer; IL 1 ; Inflammasome; Inflammation; Melanoma

Indexed keywords

CANAKINUMAB; CASPASE 1 INHIBITOR; CASPASE INHIBITOR; CRYOPYRIN; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; CXCL3 CHEMOKINE; GAMMA INTERFERON; INFLAMMASOME; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA ANTIBODY; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; PLACEBO; RANTES; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RILONACEPT; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 82355175161     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2011.10.001     Document Type: Review
Times cited : (101)

References (163)
  • 1
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: back to Virchow?
    • Balkwill F., Mantovani A. Inflammation and cancer: back to Virchow?. Lancet 2001, 357:539-545.
    • (2001) Lancet , vol.357 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 3
    • 0029816609 scopus 로고    scopus 로고
    • Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma
    • Leek R.D., Lewis C.E., Whitehouse R., Greenall M., Clarke J., Harris A.L. Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma. Cancer Res. 1996, 56:4625-4629.
    • (1996) Cancer Res. , vol.56 , pp. 4625-4629
    • Leek, R.D.1    Lewis, C.E.2    Whitehouse, R.3    Greenall, M.4    Clarke, J.5    Harris, A.L.6
  • 5
    • 65249138393 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells: linking inflammation and cancer
    • Ostrand-Rosenberg S., Sinha P. Myeloid-derived suppressor cells: linking inflammation and cancer. J. Immunol. 2009, 182:4499-4506.
    • (2009) J. Immunol. , vol.182 , pp. 4499-4506
    • Ostrand-Rosenberg, S.1    Sinha, P.2
  • 6
    • 4644335311 scopus 로고    scopus 로고
    • Cancer: an inflammatory link
    • Balkwill F., Coussens L.M. Cancer: an inflammatory link. Nature 2004, 431:405-406.
    • (2004) Nature , vol.431 , pp. 405-406
    • Balkwill, F.1    Coussens, L.M.2
  • 7
    • 0027396955 scopus 로고
    • Interleukin-6 undergoes transition from paracrine growth inhibitor to autocrine stimulator during human melanoma progression
    • Lu C., Kerbel R.S. Interleukin-6 undergoes transition from paracrine growth inhibitor to autocrine stimulator during human melanoma progression. J. Cell Biol. 1993, 120:1281-1288.
    • (1993) J. Cell Biol. , vol.120 , pp. 1281-1288
    • Lu, C.1    Kerbel, R.S.2
  • 8
    • 41149142016 scopus 로고    scopus 로고
    • Is interleukin-1 a good or bad 'guy' in tumor immunobiology and immunotherapy?
    • Apte R.N., Voronov E. Is interleukin-1 a good or bad 'guy' in tumor immunobiology and immunotherapy?. Immunol. Rev. 2008, 222:222-241.
    • (2008) Immunol. Rev. , vol.222 , pp. 222-241
    • Apte, R.N.1    Voronov, E.2
  • 9
    • 77954551165 scopus 로고    scopus 로고
    • Why not treat human cancer with interleukin-1 blockade?
    • Dinarello C.A. Why not treat human cancer with interleukin-1 blockade?. Cancer Metastasis Rev. 2010, 29:317-329.
    • (2010) Cancer Metastasis Rev. , vol.29 , pp. 317-329
    • Dinarello, C.A.1
  • 10
    • 1342332164 scopus 로고    scopus 로고
    • A continuous delivery system of IL-1 receptor antagonist reduces angiogenesis and inhibits tumor development
    • Bar D., Apte R.N., Voronov E., Dinarello C.A., Cohen S. A continuous delivery system of IL-1 receptor antagonist reduces angiogenesis and inhibits tumor development. FASEB J. 2004, 18:161-163.
    • (2004) FASEB J. , vol.18 , pp. 161-163
    • Bar, D.1    Apte, R.N.2    Voronov, E.3    Dinarello, C.A.4    Cohen, S.5
  • 14
    • 0036375050 scopus 로고    scopus 로고
    • Interleukin-1 - a major pleiotropic cytokine in tumor-host interactions
    • Apte R.N., Voronov E. Interleukin-1 - a major pleiotropic cytokine in tumor-host interactions. Semin. Cancer Biol. 2002, 12:277-290.
    • (2002) Semin. Cancer Biol. , vol.12 , pp. 277-290
    • Apte, R.N.1    Voronov, E.2
  • 16
    • 33747191203 scopus 로고    scopus 로고
    • The inflammasome: first line of the immune response to cell stress
    • Ogura Y., Sutterwala F.S., Flavell R.A. The inflammasome: first line of the immune response to cell stress. Cell 2006, 126:659-662.
    • (2006) Cell , vol.126 , pp. 659-662
    • Ogura, Y.1    Sutterwala, F.S.2    Flavell, R.A.3
  • 17
    • 33845890803 scopus 로고    scopus 로고
    • Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation
    • Mariathasan S., Monack D.M. Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation. Nat. Rev. Immunol. 2007, 7:31-40.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 31-40
    • Mariathasan, S.1    Monack, D.M.2
  • 18
    • 60749104683 scopus 로고    scopus 로고
    • The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis
    • Franchi L., Eigenbrod T., Munoz-Planillo R., Nunez G. The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis. Nat. Immunol. 2009, 10:241-247.
    • (2009) Nat. Immunol. , vol.10 , pp. 241-247
    • Franchi, L.1    Eigenbrod, T.2    Munoz-Planillo, R.3    Nunez, G.4
  • 20
    • 77949889567 scopus 로고    scopus 로고
    • Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta
    • Okamoto M., Liu W., Luo Y., Tanaka A., Cai X., Norris D.A., Dinarello C.A., Fujita M. Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta. J. Biol. Chem. 2010, 285:6477-6488.
    • (2010) J. Biol. Chem. , vol.285 , pp. 6477-6488
    • Okamoto, M.1    Liu, W.2    Luo, Y.3    Tanaka, A.4    Cai, X.5    Norris, D.A.6    Dinarello, C.A.7    Fujita, M.8
  • 21
    • 80051580618 scopus 로고    scopus 로고
    • Cancer statistics The impact of eliminating socioeconomic and racial disparities on premature cancer deaths
    • Siegel R., Ward E., Brawley O., Jemal A., Cancer statistics The impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J. Clin. 2011, 61:212-236.
    • (2011) CA Cancer J. Clin. , vol.61 , pp. 212-236
    • Siegel, R.1    Ward, E.2    Brawley, O.3    Jemal, A.4
  • 22
    • 0033011011 scopus 로고    scopus 로고
    • Update on the incidence and mortality from melanoma in the United States
    • Hall H.I., Miller D.R., Rogers J.D., Bewerse B. Update on the incidence and mortality from melanoma in the United States. J. Am. Acad. Dermatol. 1999, 40:35-42.
    • (1999) J. Am. Acad. Dermatol. , vol.40 , pp. 35-42
    • Hall, H.I.1    Miller, D.R.2    Rogers, J.D.3    Bewerse, B.4
  • 24
    • 0346880454 scopus 로고    scopus 로고
    • Cytokine gene single nucleotide polymorphisms and susceptibility to and prognosis in cutaneous malignant melanoma
    • Howell W.M., Turner S.J., Theaker J.M., Bateman A.C. Cytokine gene single nucleotide polymorphisms and susceptibility to and prognosis in cutaneous malignant melanoma. Eur. J. Immunogenet. 2003, 30:409-414.
    • (2003) Eur. J. Immunogenet. , vol.30 , pp. 409-414
    • Howell, W.M.1    Turner, S.J.2    Theaker, J.M.3    Bateman, A.C.4
  • 26
    • 62649139025 scopus 로고    scopus 로고
    • Immunological and inflammatory functions of the interleukin-1 family
    • Dinarello C.A. Immunological and inflammatory functions of the interleukin-1 family. Annu. Rev. Immunol. 2009, 27:519-550.
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 519-550
    • Dinarello, C.A.1
  • 31
    • 0028221730 scopus 로고
    • Effect of ultraviolet-inducible cytokines on melanoma growth in vivo: stimulation of melanoma growth by interleukin-1 and -6
    • McKenzie R.C., Park E.S., Brown W.R., Shivji G.S., Sauder D.N. Effect of ultraviolet-inducible cytokines on melanoma growth in vivo: stimulation of melanoma growth by interleukin-1 and -6. Photodermatol. Photoimmunol. Photomed. 1994, 10:74-79.
    • (1994) Photodermatol. Photoimmunol. Photomed. , vol.10 , pp. 74-79
    • McKenzie, R.C.1    Park, E.S.2    Brown, W.R.3    Shivji, G.S.4    Sauder, D.N.5
  • 32
    • 0028283851 scopus 로고
    • Interleukin-1 receptor blockade reduces the number and size of murine B16 melanoma hepatic metastases
    • Vidal-Vanaclocha F., Amezaga C., Asumendi A., Kaplanski G., Dinarello C.A. Interleukin-1 receptor blockade reduces the number and size of murine B16 melanoma hepatic metastases. Cancer Res. 1994, 54:2667-2672.
    • (1994) Cancer Res. , vol.54 , pp. 2667-2672
    • Vidal-Vanaclocha, F.1    Amezaga, C.2    Asumendi, A.3    Kaplanski, G.4    Dinarello, C.A.5
  • 33
    • 0030056869 scopus 로고    scopus 로고
    • Interleukin 1 (IL-1)-dependent melanoma hepatic metastasis in vivo; increased endothelial adherence by IL-1-induced mannose receptors and growth factor production in vitro
    • Vidal-Vanaclocha F., Alvarez A., Asumendi A., Urcelay B., Tonino P., Dinarello C.A. Interleukin 1 (IL-1)-dependent melanoma hepatic metastasis in vivo; increased endothelial adherence by IL-1-induced mannose receptors and growth factor production in vitro. J. Natl. Cancer Inst. 1996, 88:198-205.
    • (1996) J. Natl. Cancer Inst. , vol.88 , pp. 198-205
    • Vidal-Vanaclocha, F.1    Alvarez, A.2    Asumendi, A.3    Urcelay, B.4    Tonino, P.5    Dinarello, C.A.6
  • 34
    • 29144504335 scopus 로고    scopus 로고
    • CD11b+/Gr-1+ immature myeloid cells mediate suppression of T cells in mice bearing tumors of IL-1beta-secreting cells
    • Song X., Krelin Y., Dvorkin T., Bjorkdahl O., Segal S., Dinarello C.A., Voronov E., Apte R.N. CD11b+/Gr-1+ immature myeloid cells mediate suppression of T cells in mice bearing tumors of IL-1beta-secreting cells. J. Immunol. 2005, 175:8200-8208.
    • (2005) J. Immunol. , vol.175 , pp. 8200-8208
    • Song, X.1    Krelin, Y.2    Dvorkin, T.3    Bjorkdahl, O.4    Segal, S.5    Dinarello, C.A.6    Voronov, E.7    Apte, R.N.8
  • 35
    • 0036468297 scopus 로고    scopus 로고
    • Autocrine production of interleukin 1beta confers constitutive nuclear factor kappaB activity and chemoresistance in pancreatic carcinoma cell lines
    • Arlt A., Vorndamm J., Muerkoster S., Yu H., Schmidt W.E., Folsch U.R., Schafer H. Autocrine production of interleukin 1beta confers constitutive nuclear factor kappaB activity and chemoresistance in pancreatic carcinoma cell lines. Cancer Res. 2002, 62:910-916.
    • (2002) Cancer Res. , vol.62 , pp. 910-916
    • Arlt, A.1    Vorndamm, J.2    Muerkoster, S.3    Yu, H.4    Schmidt, W.E.5    Folsch, U.R.6    Schafer, H.7
  • 36
    • 10744221950 scopus 로고    scopus 로고
    • Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta
    • Muerkoster S., Wegehenkel K., Arlt A., Witt M., Sipos B., Kruse M.L., Sebens T., Kloppel G., Kalthoff H., Folsch U.R., Schafer H. Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta. Cancer Res. 2004, 64:1331-1337.
    • (2004) Cancer Res. , vol.64 , pp. 1331-1337
    • Muerkoster, S.1    Wegehenkel, K.2    Arlt, A.3    Witt, M.4    Sipos, B.5    Kruse, M.L.6    Sebens, T.7    Kloppel, G.8    Kalthoff, H.9    Folsch, U.R.10    Schafer, H.11
  • 37
    • 33644871737 scopus 로고    scopus 로고
    • Gene expression profiling of 30 cancer cell lines predicts resistance towards 11 anticancer drugs at clinically achieved concentrations
    • Gyorffy B., Surowiak P., Kiesslich O., Denkert C., Schafer R., Dietel M., Lage H. Gene expression profiling of 30 cancer cell lines predicts resistance towards 11 anticancer drugs at clinically achieved concentrations. Int. J. Cancer 2006, 118:1699-1712.
    • (2006) Int. J. Cancer , vol.118 , pp. 1699-1712
    • Gyorffy, B.1    Surowiak, P.2    Kiesslich, O.3    Denkert, C.4    Schafer, R.5    Dietel, M.6    Lage, H.7
  • 38
    • 0029979369 scopus 로고    scopus 로고
    • Biologic basis for interleukin-1 in disease
    • Dinarello C.A. Biologic basis for interleukin-1 in disease. Blood 1996, 87:2095-2147.
    • (1996) Blood , vol.87 , pp. 2095-2147
    • Dinarello, C.A.1
  • 40
    • 40049088602 scopus 로고    scopus 로고
    • The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages
    • Allavena P., Sica A., Solinas G., Porta C., Mantovani A. The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages. Crit. Rev. Oncol. Hematol. 2008, 66:1-9.
    • (2008) Crit. Rev. Oncol. Hematol. , vol.66 , pp. 1-9
    • Allavena, P.1    Sica, A.2    Solinas, G.3    Porta, C.4    Mantovani, A.5
  • 42
    • 0023201153 scopus 로고
    • Interleukin 1 induces interleukin 1. I. Induction of circulating interleukin 1 in rabbits in vivo and in human mononuclear cells in vitro
    • Dinarello C.A., Ikejima T., Warner S.J., Orencole S.F., Lonnemann G., Cannon J.G., Libby P. Interleukin 1 induces interleukin 1. I. Induction of circulating interleukin 1 in rabbits in vivo and in human mononuclear cells in vitro. J. Immunol. 1987, 139:1902-1910.
    • (1987) J. Immunol. , vol.139 , pp. 1902-1910
    • Dinarello, C.A.1    Ikejima, T.2    Warner, S.J.3    Orencole, S.F.4    Lonnemann, G.5    Cannon, J.G.6    Libby, P.7
  • 43
    • 0023719001 scopus 로고
    • IL-1 induces IL-1. III. Specific inhibition of IL-1 production by IFN-gamma
    • Ghezzi P., Dinarello C.A. IL-1 induces IL-1. III. Specific inhibition of IL-1 production by IFN-gamma. J. Immunol. 1988, 140:4238-4244.
    • (1988) J. Immunol. , vol.140 , pp. 4238-4244
    • Ghezzi, P.1    Dinarello, C.A.2
  • 44
    • 0025707532 scopus 로고
    • IL-1 induces IL-1. IV. IFN-gamma suppresses IL-1 but not lipopolysaccharide-induced transcription of IL-1
    • Schindler R., Ghezzi P., Dinarello C.A. IL-1 induces IL-1. IV. IFN-gamma suppresses IL-1 but not lipopolysaccharide-induced transcription of IL-1. J. Immunol. 1990, 144:2216-2222.
    • (1990) J. Immunol. , vol.144 , pp. 2216-2222
    • Schindler, R.1    Ghezzi, P.2    Dinarello, C.A.3
  • 45
    • 0023230528 scopus 로고
    • Interleukin 1 induces interleukin 1. II. Recombinant human interleukin 1 induces interleukin 1 production by adult human vascular endothelial cells
    • Warner S.J., Auger K.R., Libby P. Interleukin 1 induces interleukin 1. II. Recombinant human interleukin 1 induces interleukin 1 production by adult human vascular endothelial cells. J. Immunol. 1987, 139:1911-1917.
    • (1987) J. Immunol. , vol.139 , pp. 1911-1917
    • Warner, S.J.1    Auger, K.R.2    Libby, P.3
  • 46
    • 0023179803 scopus 로고
    • Human interleukin 1 induces interleukin 1 gene expression in human vascular smooth muscle cells
    • Warner S.J., Auger K.R., Libby P. Human interleukin 1 induces interleukin 1 gene expression in human vascular smooth muscle cells. J. Exp. Med. 1987, 165:1316-1331.
    • (1987) J. Exp. Med. , vol.165 , pp. 1316-1331
    • Warner, S.J.1    Auger, K.R.2    Libby, P.3
  • 47
    • 0026705784 scopus 로고
    • In vivo and in vitro characteristics of interleukin 6-transfected B16 melanoma cells
    • Sun W.H., Kreisle R.A., Phillips A.W., Ershler W.B. In vivo and in vitro characteristics of interleukin 6-transfected B16 melanoma cells. Cancer Res. 1992, 52:5412-5415.
    • (1992) Cancer Res. , vol.52 , pp. 5412-5415
    • Sun, W.H.1    Kreisle, R.A.2    Phillips, A.W.3    Ershler, W.B.4
  • 48
    • 0025735630 scopus 로고
    • Properties of the novel proinflammatory supergene " intercrine" cytokine family
    • Oppenheim J.J., Zachariae C.O., Mukaida N., Matsushima K. Properties of the novel proinflammatory supergene " intercrine" cytokine family. Annu. Rev. Immunol. 1991, 9:617-648.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 617-648
    • Oppenheim, J.J.1    Zachariae, C.O.2    Mukaida, N.3    Matsushima, K.4
  • 49
    • 0027279450 scopus 로고
    • IL-8 produced by human malignant melanoma cells in vitro is an essential autocrine growth factor
    • Schadendorf D., Moller A., Algermissen B., Worm M., Sticherling M., Czarnetzki B.M. IL-8 produced by human malignant melanoma cells in vitro is an essential autocrine growth factor. J. Immunol. 1993, 151:2667-2675.
    • (1993) J. Immunol. , vol.151 , pp. 2667-2675
    • Schadendorf, D.1    Moller, A.2    Algermissen, B.3    Worm, M.4    Sticherling, M.5    Czarnetzki, B.M.6
  • 50
    • 0037443760 scopus 로고    scopus 로고
    • IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis
    • Li A., Dubey S., Varney M.L., Dave B.J., Singh R.K. IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis. J. Immunol. 2003, 170:3369-3376.
    • (2003) J. Immunol. , vol.170 , pp. 3369-3376
    • Li, A.1    Dubey, S.2    Varney, M.L.3    Dave, B.J.4    Singh, R.K.5
  • 51
    • 0026051864 scopus 로고
    • Recombinant human MCP-1/JE induces chemotaxis, calcium flux, and the respiratory burst in human monocytes
    • Rollins B.J., Walz A., Baggiolini M. Recombinant human MCP-1/JE induces chemotaxis, calcium flux, and the respiratory burst in human monocytes. Blood 1991, 78:1112-1116.
    • (1991) Blood , vol.78 , pp. 1112-1116
    • Rollins, B.J.1    Walz, A.2    Baggiolini, M.3
  • 52
    • 0026547872 scopus 로고
    • Monocyte chemoattractant protein-1 regulates adhesion molecule expression and cytokine production in human monocytes
    • Jiang Y., Beller D.I., Frendl G., Graves D.T. Monocyte chemoattractant protein-1 regulates adhesion molecule expression and cytokine production in human monocytes. J. Immunol. 1992, 148:2423-2428.
    • (1992) J. Immunol. , vol.148 , pp. 2423-2428
    • Jiang, Y.1    Beller, D.I.2    Frendl, G.3    Graves, D.T.4
  • 53
    • 0028004236 scopus 로고
    • The type II 'decoy' receptor: a novel regulatory pathway for interleukin 1
    • Colotta F., Dower S.K., Sims J.E., Mantovani A. The type II 'decoy' receptor: a novel regulatory pathway for interleukin 1. Immunol. Today 1994, 15:562-566.
    • (1994) Immunol. Today , vol.15 , pp. 562-566
    • Colotta, F.1    Dower, S.K.2    Sims, J.E.3    Mantovani, A.4
  • 54
    • 0034680145 scopus 로고    scopus 로고
    • Toll-like receptors in the induction of the innate immune response
    • Aderem A., Ulevitch R.J. Toll-like receptors in the induction of the innate immune response. Nature 2000, 406:782-787.
    • (2000) Nature , vol.406 , pp. 782-787
    • Aderem, A.1    Ulevitch, R.J.2
  • 55
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: critical proteins linking innate and acquired immunity
    • Akira S., Takeda K., Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol. 2001, 2:675-680.
    • (2001) Nat. Immunol. , vol.2 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 57
    • 0036398446 scopus 로고    scopus 로고
    • The IL-1 family and inflammatory diseases
    • Dinarello C.A. The IL-1 family and inflammatory diseases. Clin. Exp. Rheumatol. 2002, 20:S1-13.
    • (2002) Clin. Exp. Rheumatol. , vol.20
    • Dinarello, C.A.1
  • 58
    • 0025255629 scopus 로고
    • A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequence
    • Rubartelli A., Cozzolino F., Talio M., Sitia R. A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequence. EMBO J. 1990, 9:1503-1510.
    • (1990) EMBO J. , vol.9 , pp. 1503-1510
    • Rubartelli, A.1    Cozzolino, F.2    Talio, M.3    Sitia, R.4
  • 59
    • 3142660196 scopus 로고    scopus 로고
    • IL-1beta: an endosomal exit
    • Wewers M.D. IL-1beta: an endosomal exit. Proc. Natl. Acad. Sci. USA 2004, 101:10241-10242.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 10241-10242
    • Wewers, M.D.1
  • 60
    • 34548614009 scopus 로고    scopus 로고
    • Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages
    • Qu Y., Franchi L., Nunez G., Dubyak G.R. Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages. J. Immunol. 2007, 179:1913-1925.
    • (2007) J. Immunol. , vol.179 , pp. 1913-1925
    • Qu, Y.1    Franchi, L.2    Nunez, G.3    Dubyak, G.R.4
  • 61
    • 3042800587 scopus 로고    scopus 로고
    • Phospholipases C and A2 control lysosome-mediated IL-1 beta secretion: Implications for inflammatory processes
    • Andrei C., Margiocco P., Poggi A., Lotti L.V., Torrisi M.R., Rubartelli A. Phospholipases C and A2 control lysosome-mediated IL-1 beta secretion: Implications for inflammatory processes. Proc. Natl. Acad. Sci. USA 2004, 101:9745-9750.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 9745-9750
    • Andrei, C.1    Margiocco, P.2    Poggi, A.3    Lotti, L.V.4    Torrisi, M.R.5    Rubartelli, A.6
  • 62
    • 18644374105 scopus 로고    scopus 로고
    • Blocking IL-1 in systemic inflammation
    • Dinarello C.A. Blocking IL-1 in systemic inflammation. J. Exp. Med. 2005, 201:1355-1359.
    • (2005) J. Exp. Med. , vol.201 , pp. 1355-1359
    • Dinarello, C.A.1
  • 63
    • 22244475444 scopus 로고    scopus 로고
    • The many worlds of reducing interleukin-1
    • Dinarello C.A. The many worlds of reducing interleukin-1. Arthritis Rheum. 2005, 52:1960-1967.
    • (2005) Arthritis Rheum. , vol.52 , pp. 1960-1967
    • Dinarello, C.A.1
  • 64
    • 0036671894 scopus 로고    scopus 로고
    • The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
    • Martinon F., Burns K., Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol. Cell 2002, 10:417-426.
    • (2002) Mol. Cell , vol.10 , pp. 417-426
    • Martinon, F.1    Burns, K.2    Tschopp, J.3
  • 66
    • 0037121940 scopus 로고    scopus 로고
    • The PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathways
    • Stehlik C., Fiorentino L., Dorfleutner A., Bruey J.M., Ariza E.M., Sagara J., Reed J.C. The PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathways. J. Exp. Med. 2002, 196:1605-1615.
    • (2002) J. Exp. Med. , vol.196 , pp. 1605-1615
    • Stehlik, C.1    Fiorentino, L.2    Dorfleutner, A.3    Bruey, J.M.4    Ariza, E.M.5    Sagara, J.6    Reed, J.C.7
  • 67
    • 34247165763 scopus 로고    scopus 로고
    • ASC, Ipaf and Cryopyrin/Nalp3: bona fide intracellular adapters of the caspase-1 inflammasome
    • Mariathasan S. ASC, Ipaf and Cryopyrin/Nalp3: bona fide intracellular adapters of the caspase-1 inflammasome. Microbes Infect. 2007, 9:664-671.
    • (2007) Microbes Infect. , vol.9 , pp. 664-671
    • Mariathasan, S.1
  • 69
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • Schroder K., Tschopp J. The inflammasomes. Cell 2010, 140:821-832.
    • (2010) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 71
    • 79953046719 scopus 로고    scopus 로고
    • The inflammasome NLRs in immunity, inflammation, and associated diseases
    • Davis B.K., Wen H., Ting J.P. The inflammasome NLRs in immunity, inflammation, and associated diseases. Annu. Rev. Immunol. 2011, 29:707-735.
    • (2011) Annu. Rev. Immunol. , vol.29 , pp. 707-735
    • Davis, B.K.1    Wen, H.2    Ting, J.P.3
  • 78
    • 1642285783 scopus 로고    scopus 로고
    • NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
    • Agostini L., Martinon F., Burns K., McDermott M.F., Hawkins P.N., Tschopp J. NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 2004, 20:319-325.
    • (2004) Immunity , vol.20 , pp. 319-325
    • Agostini, L.1    Martinon, F.2    Burns, K.3    McDermott, M.F.4    Hawkins, P.N.5    Tschopp, J.6
  • 79
    • 7944232105 scopus 로고    scopus 로고
    • Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome
    • Martinon F., Agostini L., Meylan E., Tschopp J. Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome. Curr. Biol. 2004, 14:1929-1934.
    • (2004) Curr. Biol. , vol.14 , pp. 1929-1934
    • Martinon, F.1    Agostini, L.2    Meylan, E.3    Tschopp, J.4
  • 80
    • 37549066934 scopus 로고    scopus 로고
    • Osteoblasts express NLRP3, a nucleotide-binding domain and leucine-rich repeat region containing receptor implicated in bacterially induced cell death
    • McCall S.H., Sahraei M., Young A.B., Worley C.S., Duncan J.A., Ting J.P., Marriott I. Osteoblasts express NLRP3, a nucleotide-binding domain and leucine-rich repeat region containing receptor implicated in bacterially induced cell death. J. Bone Miner. Res. 2008, 23:30-40.
    • (2008) J. Bone Miner. Res. , vol.23 , pp. 30-40
    • McCall, S.H.1    Sahraei, M.2    Young, A.B.3    Worley, C.S.4    Duncan, J.A.5    Ting, J.P.6    Marriott, I.7
  • 82
    • 63649145255 scopus 로고    scopus 로고
    • AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
    • Fernandes-Alnemri T., Yu J.W., Datta P., Wu J., Alnemri E.S. AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature 2009, 458:509-513.
    • (2009) Nature , vol.458 , pp. 509-513
    • Fernandes-Alnemri, T.1    Yu, J.W.2    Datta, P.3    Wu, J.4    Alnemri, E.S.5
  • 83
    • 33845497181 scopus 로고    scopus 로고
    • Inflammatory caspases and inflammasomes: master switches of inflammation
    • Martinon F., Tschopp J. Inflammatory caspases and inflammasomes: master switches of inflammation. Cell Death Differ. 2007, 14:10-22.
    • (2007) Cell Death Differ. , vol.14 , pp. 10-22
    • Martinon, F.1    Tschopp, J.2
  • 84
    • 31744441475 scopus 로고    scopus 로고
    • Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
    • Boyden E.D., Dietrich W.F. Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin. Nat. Genet. 2006, 38:240-244.
    • (2006) Nat. Genet. , vol.38 , pp. 240-244
    • Boyden, E.D.1    Dietrich, W.F.2
  • 90
    • 47149108866 scopus 로고    scopus 로고
    • Interferon-inducible Ifi200-family genes in systemic lupus erythematosus
    • Choubey D., Panchanathan R. Interferon-inducible Ifi200-family genes in systemic lupus erythematosus. Immunol. Lett. 2008, 119:32-41.
    • (2008) Immunol. Lett. , vol.119 , pp. 32-41
    • Choubey, D.1    Panchanathan, R.2
  • 93
    • 77749270973 scopus 로고    scopus 로고
    • Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor
    • Harder J., Franchi L., Muñoz-Planillo R., Park J.H., Reimer T., Núñez G. Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor. J. Immunol. 2009, 183:5823-5829.
    • (2009) J. Immunol. , vol.183 , pp. 5823-5829
    • Harder, J.1    Franchi, L.2    Muñoz-Planillo, R.3    Park, J.H.4    Reimer, T.5    Núñez, G.6
  • 94
    • 33748598700 scopus 로고    scopus 로고
    • Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival
    • Gurcel L., Abrami L., Girardin S., Tschopp J., van der Goot F.G. Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival. Cell 2006, 126:1135-1145.
    • (2006) Cell , vol.126 , pp. 1135-1145
    • Gurcel, L.1    Abrami, L.2    Girardin, S.3    Tschopp, J.4    van der Goot, F.G.5
  • 96
    • 70349334298 scopus 로고    scopus 로고
    • A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome
    • Munoz-Planillo R., Franchi L., Miller L.S., Nunez G. A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome. J. Immunol. 2009, 183:3942-3948.
    • (2009) J. Immunol. , vol.183 , pp. 3942-3948
    • Munoz-Planillo, R.1    Franchi, L.2    Miller, L.S.3    Nunez, G.4
  • 98
    • 32944468985 scopus 로고    scopus 로고
    • Gout-associated uric acid crystals activate the NALP3 inflammasome
    • Martinon F., Petrilli V., Mayor A., Tardivel A., Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 2006, 440:237-241.
    • (2006) Nature , vol.440 , pp. 237-241
    • Martinon, F.1    Petrilli, V.2    Mayor, A.3    Tardivel, A.4    Tschopp, J.5
  • 99
    • 75649096002 scopus 로고    scopus 로고
    • Thioredoxin-interacting protein links oxidative stress to inflammasome activation
    • Zhou R., Tardivel A., Thorens B., Choi I., Tschopp J. Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat. Immunol. 2010, 11:136-140.
    • (2010) Nat. Immunol. , vol.11 , pp. 136-140
    • Zhou, R.1    Tardivel, A.2    Thorens, B.3    Choi, I.4    Tschopp, J.5
  • 102
    • 43249125839 scopus 로고    scopus 로고
    • Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
    • Dostert C., Pétrilli V., Van Bruggen R., Steele C., Mossman B.T., Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 2008, 320:674-677.
    • (2008) Science , vol.320 , pp. 674-677
    • Dostert, C.1    Pétrilli, V.2    Van Bruggen, R.3    Steele, C.4    Mossman, B.T.5    Tschopp, J.6
  • 104
    • 34250835251 scopus 로고    scopus 로고
    • The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes
    • Feldmeyer L., Keller M., Niklaus G., Hohl D., Werner S., Beer H.D. The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes. Curr. Biol. 2007, 17:1140-1145.
    • (2007) Curr. Biol. , vol.17 , pp. 1140-1145
    • Feldmeyer, L.1    Keller, M.2    Niklaus, G.3    Hohl, D.4    Werner, S.5    Beer, H.D.6
  • 105
    • 34047261260 scopus 로고    scopus 로고
    • ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages
    • Cruz C.M., Rinna A., Forman H.J., Ventura A.L., Persechini P.M., Ojcius D.M. ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages. J. Biol. Chem. 2007, 282:2871-2879.
    • (2007) J. Biol. Chem. , vol.282 , pp. 2871-2879
    • Cruz, C.M.1    Rinna, A.2    Forman, H.J.3    Ventura, A.L.4    Persechini, P.M.5    Ojcius, D.M.6
  • 106
    • 78651393239 scopus 로고    scopus 로고
    • A role for mitochondria in NLRP3 inflammasome activation
    • Zhou R., Yazdi A.S., Menu P., Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature 2011, 469:221-225.
    • (2011) Nature , vol.469 , pp. 221-225
    • Zhou, R.1    Yazdi, A.S.2    Menu, P.3    Tschopp, J.4
  • 108
    • 28844437999 scopus 로고    scopus 로고
    • Poxviruses aren't stuPYD
    • Benedict C.A., Ware C.F. Poxviruses aren't stuPYD. Immunity 2005, 23:553-555.
    • (2005) Immunity , vol.23 , pp. 553-555
    • Benedict, C.A.1    Ware, C.F.2
  • 109
    • 34247265509 scopus 로고    scopus 로고
    • A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses
    • Mayor A., Martinon F., De Smedt T., Petrilli V., Tschopp J. A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses. Nat. Immunol. 2007, 8:497-503.
    • (2007) Nat. Immunol. , vol.8 , pp. 497-503
    • Mayor, A.1    Martinon, F.2    De Smedt, T.3    Petrilli, V.4    Tschopp, J.5
  • 111
    • 62649092113 scopus 로고    scopus 로고
    • Mechanism of Bcl-2 and Bcl-X(L) inhibition of NLRP1 inflammasome: loop domain-dependent suppression of ATP binding and oligomerization
    • Faustin B., Chen Y., Zhai D., Le Negrate G., Lartigue L., Satterthwait A., Reed J.C. Mechanism of Bcl-2 and Bcl-X(L) inhibition of NLRP1 inflammasome: loop domain-dependent suppression of ATP binding and oligomerization. Proc. Natl. Acad. Sci. USA 2009, 106:3935-3940.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 3935-3940
    • Faustin, B.1    Chen, Y.2    Zhai, D.3    Le Negrate, G.4    Lartigue, L.5    Satterthwait, A.6    Reed, J.C.7
  • 114
    • 1442277112 scopus 로고    scopus 로고
    • TMS1/ASC: the cancer connection
    • McConnell B.B., Vertino P.M. TMS1/ASC: the cancer connection. Apoptosis 2004, 9:5-18.
    • (2004) Apoptosis , vol.9 , pp. 5-18
    • McConnell, B.B.1    Vertino, P.M.2
  • 115
    • 77953813317 scopus 로고    scopus 로고
    • Differential splicing of the apoptosis-associated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomes
    • Bryan N.B., Dorfleutner A., Kramer S.J., Yun C., Rojanasakul Y., Stehlik C. Differential splicing of the apoptosis-associated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomes. J. Inflamm. (Lond.) 2010, 7:23.
    • (2010) J. Inflamm. (Lond.) , vol.7 , pp. 23
    • Bryan, N.B.1    Dorfleutner, A.2    Kramer, S.J.3    Yun, C.4    Rojanasakul, Y.5    Stehlik, C.6
  • 116
    • 64849097220 scopus 로고    scopus 로고
    • Activation of inflammasomes requires intracellular redistribution of the apoptotic speck-like protein containing a caspase recruitment domain
    • Bryan N.B., Dorfleutner A., Rojanasakul Y., Stehlik C. Activation of inflammasomes requires intracellular redistribution of the apoptotic speck-like protein containing a caspase recruitment domain. J. Immunol. 2009, 182:3173-3182.
    • (2009) J. Immunol. , vol.182 , pp. 3173-3182
    • Bryan, N.B.1    Dorfleutner, A.2    Rojanasakul, Y.3    Stehlik, C.4
  • 118
    • 40049108218 scopus 로고    scopus 로고
    • COPs and POPs: modulators of inflammasome activity
    • Stehlik C., Dorfleutner A. COPs and POPs: modulators of inflammasome activity. J. Immunol. 2007, 179:7993-7998.
    • (2007) J. Immunol. , vol.179 , pp. 7993-7998
    • Stehlik, C.1    Dorfleutner, A.2
  • 119
    • 0344823965 scopus 로고    scopus 로고
    • Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway
    • Shoham N.G., Centola M., Mansfield E., Hull K.M., Wood G., Wise C.A., Kastner D.L. Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway. Proc. Natl. Acad. Sci. USA 2003, 100:13501-13506.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 13501-13506
    • Shoham, N.G.1    Centola, M.2    Mansfield, E.3    Hull, K.M.4    Wood, G.5    Wise, C.A.6    Kastner, D.L.7
  • 120
    • 0037091012 scopus 로고    scopus 로고
    • Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder
    • Wise C.A., Gillum J.D., Seidman C.E., Lindor N.M., Veile R., Bashiardes S., Lovett M. Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder. Hum. Mol. Genet. 2002, 11:961-969.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 961-969
    • Wise, C.A.1    Gillum, J.D.2    Seidman, C.E.3    Lindor, N.M.4    Veile, R.5    Bashiardes, S.6    Lovett, M.7
  • 121
    • 79956299492 scopus 로고    scopus 로고
    • Gain-of-function pyrin mutations induce NLRP3 protein-independent interleukin-1β activation and severe autoinflammation in mice
    • Chae J.J., Cho Y.H., Lee G.S., Cheng J., Liu P.P., Feigenbaum L., Katz S.I., Kastner D.L. Gain-of-function pyrin mutations induce NLRP3 protein-independent interleukin-1β activation and severe autoinflammation in mice. Immunity 2011, 34:755-768.
    • (2011) Immunity , vol.34 , pp. 755-768
    • Chae, J.J.1    Cho, Y.H.2    Lee, G.S.3    Cheng, J.4    Liu, P.P.5    Feigenbaum, L.6    Katz, S.I.7    Kastner, D.L.8
  • 122
    • 79956307337 scopus 로고    scopus 로고
    • A new twist on the PYRIN mediterranean coast
    • Franchi L., Núñez G. A new twist on the PYRIN mediterranean coast. Immunity 2011, 34:695-697.
    • (2011) Immunity , vol.34 , pp. 695-697
    • Franchi, L.1    Núñez, G.2
  • 125
    • 0036302235 scopus 로고    scopus 로고
    • Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes
    • Feldmann J., Prieur A.M., Quartier P., Berquin P., Certain S., Cortis E., Teillac-Hamel D., Fischer A., de Saint Basile G. Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes. Am. J. Hum. Genet. 2002, 71:198-203.
    • (2002) Am. J. Hum. Genet. , vol.71 , pp. 198-203
    • Feldmann, J.1    Prieur, A.M.2    Quartier, P.3    Berquin, P.4    Certain, S.5    Cortis, E.6    Teillac-Hamel, D.7    Fischer, A.8    de Saint Basile, G.9
  • 128
    • 33745631232 scopus 로고    scopus 로고
    • The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production
    • Chae J.J., Wood G., Masters S.L., Richard K., Park G., Smith B.J., Kastner D.L. The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production. Proc. Natl. Acad. Sci. USA 2006, 103:9982-9987.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 9982-9987
    • Chae, J.J.1    Wood, G.2    Masters, S.L.3    Richard, K.4    Park, G.5    Smith, B.J.6    Kastner, D.L.7
  • 129
    • 18644370644 scopus 로고    scopus 로고
    • Rapid responses to anakinra in patients with refractory adult-onset Still's disease
    • Fitzgerald A.A., Leclercq S.A., Yan A., Homik J.E., Dinarello C.A. Rapid responses to anakinra in patients with refractory adult-onset Still's disease. Arthritis Rheum. 2005, 52:1794-1803.
    • (2005) Arthritis Rheum. , vol.52 , pp. 1794-1803
    • Fitzgerald, A.A.1    Leclercq, S.A.2    Yan, A.3    Homik, J.E.4    Dinarello, C.A.5
  • 130
    • 18644385243 scopus 로고    scopus 로고
    • Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade
    • Pascual V., Allantaz F., Arce E., Punaro M., Banchereau J. Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade. J. Exp. Med. 2005, 201:1479-1486.
    • (2005) J. Exp. Med. , vol.201 , pp. 1479-1486
    • Pascual, V.1    Allantaz, F.2    Arce, E.3    Punaro, M.4    Banchereau, J.5
  • 131
    • 33846139340 scopus 로고    scopus 로고
    • Pathogenesis of familial periodic fever syndromes or hereditary autoinflammatory syndromes
    • Simon A., van der Meer J.W. Pathogenesis of familial periodic fever syndromes or hereditary autoinflammatory syndromes. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007, 292:R86-98.
    • (2007) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.292
    • Simon, A.1    van der Meer, J.W.2
  • 138
    • 25844459154 scopus 로고    scopus 로고
    • NF-kappaB: linking inflammation and immunity to cancer development and progression
    • Karin M., Greten F.R. NF-kappaB: linking inflammation and immunity to cancer development and progression. Nat. Rev. Immunol. 2005, 5:749-759.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 749-759
    • Karin, M.1    Greten, F.R.2
  • 139
  • 141
    • 77950002937 scopus 로고    scopus 로고
    • The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis
    • Zaki M.H., Boyd K.L., Vogel P., Kastan M.B., Lamkanfi M., Kanneganti T.D. The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. Immunity 2010, 32:379-391.
    • (2010) Immunity , vol.32 , pp. 379-391
    • Zaki, M.H.1    Boyd, K.L.2    Vogel, P.3    Kastan, M.B.4    Lamkanfi, M.5    Kanneganti, T.D.6
  • 143
    • 72449179439 scopus 로고    scopus 로고
    • Oncolytic adenovirus expressing interleukin-18 induces significant antitumor effects against melanoma in mice through inhibition of angiogenesis
    • Zheng J.N., Pei D.S., Mao L.J., Liu X.Y., Sun F.H., Zhang B.F., Liu Y.Q., Liu J.J., Li W., Han D. Oncolytic adenovirus expressing interleukin-18 induces significant antitumor effects against melanoma in mice through inhibition of angiogenesis. Cancer Gene Ther. 2010, 17:28-36.
    • (2010) Cancer Gene Ther. , vol.17 , pp. 28-36
    • Zheng, J.N.1    Pei, D.S.2    Mao, L.J.3    Liu, X.Y.4    Sun, F.H.5    Zhang, B.F.6    Liu, Y.Q.7    Liu, J.J.8    Li, W.9    Han, D.10
  • 146
    • 17144455957 scopus 로고    scopus 로고
    • Endogenous interleukin-18 modulates immune escape of murine melanoma cells by regulating the expression of Fas ligand and reactive oxygen intermediates
    • Cho D., Song H., Kim Y.M., Houh D., Hur D.Y., Park H., Yoon D., Pyun K.H., Lee W.J., Kurimoto M., Kim Y.B., Kim Y.S., Choi I. Endogenous interleukin-18 modulates immune escape of murine melanoma cells by regulating the expression of Fas ligand and reactive oxygen intermediates. Cancer Res. 2000, 60:2703-2709.
    • (2000) Cancer Res. , vol.60 , pp. 2703-2709
    • Cho, D.1    Song, H.2    Kim, Y.M.3    Houh, D.4    Hur, D.Y.5    Park, H.6    Yoon, D.7    Pyun, K.H.8    Lee, W.J.9    Kurimoto, M.10    Kim, Y.B.11    Kim, Y.S.12    Choi, I.13
  • 147
    • 80054901319 scopus 로고    scopus 로고
    • Green tea polyphenol epigallocatechin-3-gallate suppresses melanoma growth by inhibiting inflammasome and IL-1β secretion
    • in press, [Epub ahead of print]. doi:10.1016/j./bbrc.2011.09.115
    • L.Z. Ellis, W. Liu, Y. Luo, M. Okamoto, D. Qu, J.H. Dunn, M. Fujita, Green tea polyphenol epigallocatechin-3-gallate suppresses melanoma growth by inhibiting inflammasome and IL-1β secretion. Biochem. Biophys. Res. Commun., (2011), in press, [Epub ahead of print]. doi:10.1016/j./bbrc.2011.09.115.
    • (2011) Biochem. Biophys. Res. Commun.
    • Ellis, L.Z.1    Liu, W.2    Luo, Y.3    Okamoto, M.4    Qu, D.5    Dunn, J.H.6    Fujita, M.7
  • 150
    • 79959221313 scopus 로고    scopus 로고
    • Inflammasome-mediated suppression of inflammation-induced colorectal cancer progression is mediated by direct regulation of epithelial cell proliferation
    • Hu B., Elinav E., Flavell R.A. Inflammasome-mediated suppression of inflammation-induced colorectal cancer progression is mediated by direct regulation of epithelial cell proliferation. Cell Cycle 2011, 10:1936-1939.
    • (2011) Cell Cycle , vol.10 , pp. 1936-1939
    • Hu, B.1    Elinav, E.2    Flavell, R.A.3
  • 151
    • 57749094105 scopus 로고    scopus 로고
    • The innate immune receptor Nod1 protects the intestine from inflammation-induced tumorigenesis
    • Chen G.Y., Shaw M.H., Redondo G., Nunez G. The innate immune receptor Nod1 protects the intestine from inflammation-induced tumorigenesis. Cancer Res. 2008, 68:10060-10067.
    • (2008) Cancer Res. , vol.68 , pp. 10060-10067
    • Chen, G.Y.1    Shaw, M.H.2    Redondo, G.3    Nunez, G.4
  • 154
    • 0036875365 scopus 로고    scopus 로고
    • A proapoptotic caspase recruitment domain protein gene, TMS1, is hypermethylated in human breast and gastric cancers
    • Moriai R., Tsuji N., Kobayashi D., Yagihashi A., Namiki Y., Takahashi H., Watanabe N. A proapoptotic caspase recruitment domain protein gene, TMS1, is hypermethylated in human breast and gastric cancers. Anticancer Res. 2002, 22:4163-4168.
    • (2002) Anticancer Res. , vol.22 , pp. 4163-4168
    • Moriai, R.1    Tsuji, N.2    Kobayashi, D.3    Yagihashi, A.4    Namiki, Y.5    Takahashi, H.6    Watanabe, N.7
  • 156
    • 0141857814 scopus 로고    scopus 로고
    • ASC/TMS1, a caspase-1 activating adaptor, is downregulated by aberrant methylation in human melanoma
    • Guan X., Sagara J., Yokoyama T., Koganehira Y., Oguchi M., Saida T., Taniguchi S. ASC/TMS1, a caspase-1 activating adaptor, is downregulated by aberrant methylation in human melanoma. Int. J. Cancer 2003, 107:202-208.
    • (2003) Int. J. Cancer , vol.107 , pp. 202-208
    • Guan, X.1    Sagara, J.2    Yokoyama, T.3    Koganehira, Y.4    Oguchi, M.5    Saida, T.6    Taniguchi, S.7
  • 158
    • 79957624096 scopus 로고    scopus 로고
    • The NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasome
    • Taxman D.J., Holley-Guthrie E.A., Huang M.T., Moore C.B., Bergstralh D.T., Allen I.C., Lei Y., Gris D., Ting J.P. The NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasome. J. Biol. Chem. 2011, 286:19605-19616.
    • (2011) J. Biol. Chem. , vol.286 , pp. 19605-19616
    • Taxman, D.J.1    Holley-Guthrie, E.A.2    Huang, M.T.3    Moore, C.B.4    Bergstralh, D.T.5    Allen, I.C.6    Lei, Y.7    Gris, D.8    Ting, J.P.9
  • 159
    • 33744495746 scopus 로고    scopus 로고
    • F.H. van den Hoogen, Observational study on efficacy, safety, and drug survival of anakinra in rheumatoid arthritis patients in clinical practice
    • den Broeder A.A., de Jong E., Franssen M.J., Jeurissen M.E., Flendrie M. F.H. van den Hoogen, Observational study on efficacy, safety, and drug survival of anakinra in rheumatoid arthritis patients in clinical practice. Ann. Rheum. Dis. 2006, 65:760-762.
    • (2006) Ann. Rheum. Dis. , vol.65 , pp. 760-762
    • den Broeder, A.A.1    de Jong, E.2    Franssen, M.J.3    Jeurissen, M.E.4    Flendrie, M.5
  • 161
    • 23444439667 scopus 로고    scopus 로고
    • IL-converting enzyme/caspase-1 inhibitor VX-765 blocks the hypersensitive response to an inflammatory stimulus in monocytes from familial cold autoinflammatory syndrome patients
    • Stack J.H., Beaumont K., Larsen P.D., Straley K.S., Henkel G.W., Randle J.C., Hoffman H.M. IL-converting enzyme/caspase-1 inhibitor VX-765 blocks the hypersensitive response to an inflammatory stimulus in monocytes from familial cold autoinflammatory syndrome patients. J. Immunol. 2005, 175:2630-2634.
    • (2005) J. Immunol. , vol.175 , pp. 2630-2634
    • Stack, J.H.1    Beaumont, K.2    Larsen, P.D.3    Straley, K.S.4    Henkel, G.W.5    Randle, J.C.6    Hoffman, H.M.7
  • 163
    • 0037309790 scopus 로고    scopus 로고
    • Interleukin 1 receptor antagonist anakinra improves functional status in patients with rheumatoid arthritis
    • Cohen S.B., Woolley J.M., Chan W. Interleukin 1 receptor antagonist anakinra improves functional status in patients with rheumatoid arthritis. J. Rheumatol. 2003, 30:225-231.
    • (2003) J. Rheumatol. , vol.30 , pp. 225-231
    • Cohen, S.B.1    Woolley, J.M.2    Chan, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.