The PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor κB activation pathways

Journal of Experimental Medicine

Volumn 196, Issue 12, 2002, Pages 1605-1615

  Stehlik, Christian ^a   Fiorentino, Loredana ^a   Dorfleutner, Andrea ^a   Bruey, Jean Marie ^a   Ariza, Eugenia M ^a   Sagara, Junji ^b   Reed, John C ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

I B kinase; Inflammation; Monocytes; NF B; Signal transduction

Indexed keywords

I KAPPA B ALPHA; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; PROTEIN; PROTEIN ASC; RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOARCHITECTURE; EMBRYO; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME INDUCTION; ENZYME INHIBITION; HAMSTER; HUMAN; HUMAN CELL; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STIMULUS;

BINDING SITES; CELL LINE; CYTOSKELETAL PROTEINS; GENES, REPORTER; HUMANS; I-KAPPA B KINASE; MACROMOLECULAR SUBSTANCES; NF-KAPPA B; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; RECOMBINANT FUSION PROTEINS; TNF RECEPTOR-ASSOCIATED FACTOR 1; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0037121940     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20021552     Document Type: Article

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