-
1
-
-
0032923377
-
The secretory route of the leaderless protein interleukin 1beta involves exocytosis of endolysosome-related vesicles
-
Andrei, C., C. Dazzi, L. Lotti, M.R. Torrisi, G. Chimini, and A. Rubartelli. 1999. The secretory route of the leaderless protein interleukin 1beta involves exocytosis of endolysosome-related vesicles. Mol. Biol. Cell. 10:1463-1475.
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 1463-1475
-
-
Andrei, C.1
Dazzi, C.2
Lotti, L.3
Torrisi, M.R.4
Chimini, G.5
Rubartelli, A.6
-
3
-
-
0042242912
-
Essential role for Ca2+ in the regulation of IL-1β secretion by P2X7 nucleotide receptor in monocytes, macrophages, and HEK-293 cells
-
Gudipaty, L., J. Munetz, P.A. Verhoef, and G.R. Dubyak. 2003. Essential role for Ca2+ in the regulation of IL-1β secretion by P2X7 nucleotide receptor in monocytes, macrophages, and HEK-293 cells. Am. J. Physiol. Cell Physiol. 285:C286-C299.
-
(2003)
Am. J. Physiol. Cell Physiol.
, vol.285
-
-
Gudipaty, L.1
Munetz, J.2
Verhoef, P.A.3
Dubyak, G.R.4
-
4
-
-
0035808396
-
Altered cytokine production in mice lacking P2X(7) receptors
-
Solle, M., J. Labasi, D.G. Perregaux, E. Stam, N. Petrushova, B.H. Koller, R.J. Griffiths, and C.A. Gabel. 2001. Altered cytokine production in mice lacking P2X(7) receptors. J. Biol. Chem. 276:125-132.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 125-132
-
-
Solle, M.1
Labasi, J.2
Perregaux, D.G.3
Stam, E.4
Petrushova, N.5
Koller, B.H.6
Griffiths, R.J.7
Gabel, C.A.8
-
5
-
-
1842581655
-
A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release
-
Elssner, A., M. Duncan, M. Gavrilin, and M.D. Wewers. 2004. A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release. J. Immunol. 172:4987-4994.
-
(2004)
J. Immunol.
, vol.172
, pp. 4987-4994
-
-
Elssner, A.1
Duncan, M.2
Gavrilin, M.3
Wewers, M.D.4
-
6
-
-
3042800587
-
Phospholipases C and A2 control lysosome-mediated IL-1 beta secretion: Implications for inflammatory processes
-
Andrei, C., P. Margiocco, A. Poggi, L.V. Lotti, M.R. Torrisi, and A. Rubartelli. 2004. Phospholipases C and A2 control lysosome-mediated IL-1 beta secretion: implications for inflammatory processes. Proc. Natl. Acad. Sci. USA. 101:9745-9750.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 9745-9750
-
-
Andrei, C.1
Margiocco, P.2
Poggi, A.3
Lotti, L.V.4
Torrisi, M.R.5
Rubartelli, A.6
-
7
-
-
18644385243
-
Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade
-
Pascual, V., F. Allantaz, E. Arce, M. Punaro, and J. Banchereau. 2005. Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade. J. Exp. Med. 201:1477-1484.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1477-1484
-
-
Pascual, V.1
Allantaz, F.2
Arce, E.3
Punaro, M.4
Banchereau, J.5
-
8
-
-
5044223401
-
Effective use of the recombinant interleukin 1 receptor antagonist anakinra in therapy resistant systemic onset juvenile rheumatoid arthritis
-
Verbsky, J.W., and A.J. White. 2004. Effective use of the recombinant interleukin 1 receptor antagonist anakinra in therapy resistant systemic onset juvenile rheumatoid arthritis. J. Rheumatol. 31:2071-2075.
-
(2004)
J. Rheumatol.
, vol.31
, pp. 2071-2075
-
-
Verbsky, J.W.1
White, A.J.2
-
9
-
-
0037231664
-
Cytokine traps: Multi-component, high-affinity blockers of cytokine action
-
Economides, A.N., L.R. Carpenter, J.S. Rudge, V. Wong, E.M. Kochler-Stec, C. Hartnett, E.A. Pyles, X. Xu, T.J. Daly, M.R. Young, et al. 2003. Cytokine traps: multi-component, high-affinity blockers of cytokine action. Nat. Med. 9:47-52.
-
(2003)
Nat. Med.
, vol.9
, pp. 47-52
-
-
Economides, A.N.1
Carpenter, L.R.2
Rudge, J.S.3
Wong, V.4
Kochler-Stec, E.M.5
Hartnett, C.6
Pyles, E.A.7
Xu, X.8
Daly, T.J.9
Young, M.R.10
-
10
-
-
18644370644
-
Rapid response to anakinra in patients with refractory adult onset Still's disease
-
In press
-
Fitzgerald, A.A., S.A. LeClercq, A. Yan, J.E. Homik, and C.A. Dinarello. 2005. Rapid response to anakinra in patients with refractory adult onset Still's disease. Arthritis Rheum. In press.
-
(2005)
Arthritis Rheum
-
-
Fitzgerald, A.A.1
LeClercq, S.A.2
Yan, A.3
Homik, J.E.4
Dinarello, C.A.5
-
11
-
-
0032078976
-
Regulation of inhibitory pathways of the interleukin-1 system
-
Mantovani, A., M. Muzio, P. Ghezzi, C. Colotta, and M. Introna. 1998. Regulation of inhibitory pathways of the interleukin-1 system. Ann. N. Y. Acad. Sci. 840:338-351.
-
(1998)
Ann. N. Y. Acad. Sci.
, vol.840
, pp. 338-351
-
-
Mantovani, A.1
Muzio, M.2
Ghezzi, P.3
Colotta, C.4
Introna, M.5
-
12
-
-
0029979369
-
Biological basis for interleukin-1 in disease
-
Dinarello, C.A. 1996. Biological basis for interleukin-1 in disease. Blood. 87:2095-2147.
-
(1996)
Blood
, vol.87
, pp. 2095-2147
-
-
Dinarello, C.A.1
-
13
-
-
8444225132
-
Prevention of cold-associated acute inflammation in familail cold autoinflammatory syndrome by interleukin-1 receptor antagonist prevents
-
Hoffman, H.M., S. Rosengren, D.L. Boyle, J.Y. Cho, J. Nayar, J.L. Mueller, J.P. Anderson, A.A. Wanderer, and G.S. Firestein. 2004. Prevention of cold-associated acute inflammation in familail cold autoinflammatory syndrome by interleukin-1 receptor antagonist prevents. Lancet. 364:1779-1785.
-
(2004)
Lancet
, vol.364
, pp. 1779-1785
-
-
Hoffman, H.M.1
Rosengren, S.2
Boyle, D.L.3
Cho, J.Y.4
Nayar, J.5
Mueller, J.L.6
Anderson, J.P.7
Wanderer, A.A.8
Firestein, G.S.9
-
14
-
-
20844443726
-
Interleukin-1 receptor antagonist anakinra in the treatment of neonatal onset multisystem inflammatory disease
-
Dailey, N.J., I. Aksentijevich, J.J. Chae, R. Wesley, C. Snyder, M. Magalnick, W.T. Watford, A. Gelabert, J. Jones, T.-H. Pham, et al. 2004. Interleukin-1 receptor antagonist anakinra in the treatment of neonatal onset multisystem inflammatory disease. Arthritis Rheum. 50:S440.
-
(2004)
Arthritis Rheum.
, vol.50
-
-
Dailey, N.J.1
Aksentijevich, I.2
Chae, J.J.3
Wesley, R.4
Snyder, C.5
Magalnick, M.6
Watford, W.T.7
Gelabert, A.8
Jones, J.9
Pham, T.-H.10
-
15
-
-
1042290321
-
Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra
-
Hawkins, P.N., H.J. Lachmann, E. Aganna, and M.F. McDermott. 2004. Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra. Arthritis Rheum. 50:607-612.
-
(2004)
Arthritis Rheum.
, vol.50
, pp. 607-612
-
-
Hawkins, P.N.1
Lachmann, H.J.2
Aganna, E.3
McDermott, M.F.4
-
16
-
-
17244381937
-
Interleukin-1 blockade by anakinra improves clinical symptoms in patients with neonatal onset multisystem inflammatory disease
-
Lovell, D.J., and S.L. Bowyer. 2003. Interleukin-1 blockade by anakinra improves clinical symptoms in patients with neonatal onset multisystem inflammatory disease. Arthritis Rheum. 52:1283-1286.
-
(2003)
Arthritis Rheum.
, vol.52
, pp. 1283-1286
-
-
Lovell, D.J.1
Bowyer, S.L.2
-
17
-
-
1642285783
-
NALP3 forms an IL-1β processing inflammasome with increased activity in Muckle-Wells auto-inflammatory disorder
-
Agostini, L., F. Martinon, K. Burns, M.F. McDermott, P.N. Hawkins, and J. Tschopp. 2004. NALP3 forms an IL-1β processing inflammasome with increased activity in Muckle-Wells auto-inflammatory disorder. Immunity. 20:319-325.
-
(2004)
Immunity
, vol.20
, pp. 319-325
-
-
Agostini, L.1
Martinon, F.2
Burns, K.3
McDermott, M.F.4
Hawkins, P.N.5
Tschopp, J.6
-
18
-
-
85081150931
-
Anakinra in mutation-negative NO-MID-CINCA syndrome: Comment on articles by Hawkins et al and Hoffman and Patel
-
Frenkel, J., N.M. Wulffrant, and W. Kuis. 2004. Anakinra in mutation-negative NO-MID-CINCA syndrome: comment on articles by Hawkins et al and Hoffman and Patel. Arthr Rheumat 50:3738-3739.
-
(2004)
Arthr Rheumat.
, vol.50
, pp. 3738-3739
-
-
Frenkel, J.1
Wulffrant, N.M.2
Kuis, W.3
-
19
-
-
14944380059
-
Anakinra for flares of pyogenic arthritis in PAPA syndrome
-
Dierselhuis, M.P., J. Frenkel, N.M. Wulffraat, and J.J. Boelens. 2005. Anakinra for flares of pyogenic arthritis in PAPA syndrome. Rheumatology. 44:406-408.
-
(2005)
Rheumatology
, vol.44
, pp. 406-408
-
-
Dierselhuis, M.P.1
Frenkel, J.2
Wulffraat, N.M.3
Boelens, J.J.4
-
20
-
-
0344823965
-
Pyrin binds the PSTP1P1/ CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway
-
Shoham, N.G., M. Centola, E. Mansfield, K.M. Hull, G. Wood, C.A. Wise, and D.L. Kastner. 2003. Pyrin binds the PSTP1P1/ CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway. Proc. Natl. Acad. Sci. USA. 100:13501-13506.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 13501-13506
-
-
Shoham, N.G.1
Centola, M.2
Mansfield, E.3
Hull, K.M.4
Wood, G.5
Wise, C.A.6
Kastner, D.L.7
-
21
-
-
0037349294
-
Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis
-
Chae, J.J., H.D. Komarow, J. Cheng, G. Wood, N. Raben, P.P. Liu, and D.L. Kastner. 2003. Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis. Mol. Cell. 11:591-604.
-
(2003)
Mol. Cell
, vol.11
, pp. 591-604
-
-
Chae, J.J.1
Komarow, H.D.2
Cheng, J.3
Wood, G.4
Raben, N.5
Liu, P.P.6
Kastner, D.L.7
-
22
-
-
0034929774
-
ICE/caspase-1 inhibitors as novel anti-inflammatory drugs
-
Randle, J.C., M.W. Harding, G. Ku, M. Schonharting, and R. Kurrle. 2001. ICE/Caspase-1 inhibitors as novel anti-inflammatory drugs. Expert Opin. Investig. Drugs. 10:1207-1209.
-
(2001)
Expert Opin. Investig. Drugs
, vol.10
, pp. 1207-1209
-
-
Randle, J.C.1
Harding, M.W.2
Ku, G.3
Schonharting, M.4
Kurrle, R.5
-
23
-
-
1942422683
-
Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release
-
Kahlenberg, J.M., and G.R. Dubyak. 2004. Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release. Am. J. Physiol. Cell Physiol. 286:C1100-C1108.
-
(2004)
Am. J. Physiol. Cell Physiol.
, vol.286
-
-
Kahlenberg, J.M.1
Dubyak, G.R.2
-
24
-
-
0028004236
-
The type II "decoy" receptor: A novel regulatory pathway for interleukin-1
-
Colotta, F., S.K. Dower, J.E. Sims, and A. Mantovani. 1994. The type II "decoy" receptor: a novel regulatory pathway for interleukin-1. Immunol. Today. 15:562-566.
-
(1994)
Immunol. Today
, vol.15
, pp. 562-566
-
-
Colotta, F.1
Dower, S.K.2
Sims, J.E.3
Mantovani, A.4
-
25
-
-
0034657781
-
IL-1 signaling cascade in liver cells and the involvement of a soluble form of the IL-1 receptor accessory protein
-
Jensen, L.E., M. Muzio, A. Mantovani, and A.S. Whitehead. 2000. IL-1 signaling cascade in liver cells and the involvement of a soluble form of the IL-1 receptor accessory protein. J. Immunol. 164:5277-5286.
-
(2000)
J. Immunol.
, vol.164
, pp. 5277-5286
-
-
Jensen, L.E.1
Muzio, M.2
Mantovani, A.3
Whitehead, A.S.4
-
26
-
-
0037237908
-
The soluble form of IL-1 receptor accessory protein enhances the ability of soluble type II IL-1 receptor to inhibit IL-1 action
-
Smith, D.E., R. Hanna, F. Della, H. Moore, H. Chen, A.M. Farese, T.J. MacVittie, G.D. Virca, and J.E. Sims. 2003. The soluble form of IL-1 receptor accessory protein enhances the ability of soluble type II IL-1 receptor to inhibit IL-1 action. Immunity. 18:87-96.
-
(2003)
Immunity
, vol.18
, pp. 87-96
-
-
Smith, D.E.1
Hanna, R.2
Della, F.3
Moore, H.4
Chen, H.5
Farese, A.M.6
MacVittie, T.J.7
Virca, G.D.8
Sims, J.E.9
-
27
-
-
8344261590
-
Infection, fever, and exogenous and endogenous pyrogens: Some concepts have changed
-
Dinarello, C.A. 2004. Infection, fever, and exogenous and endogenous pyrogens: some concepts have changed. J. Endotoxin Res. 10:201-222.
-
(2004)
J. Endotoxin Res.
, vol.10
, pp. 201-222
-
-
Dinarello, C.A.1
|