-
1
-
-
0037231664
-
Cytokine traps: Multi-component, high-affinity blockers of cytokine action
-
Economides AN, Carpenter LR, Rudge JS, Wong V, Koehler-Stec EM, Hartnett C, et al. Cytokine traps: multi-component, high-affinity blockers of cytokine action. Nat Med 2003;9:47-52.
-
(2003)
Nat Med
, vol.9
, pp. 47-52
-
-
Economides, A.N.1
Carpenter, L.R.2
Rudge, J.S.3
Wong, V.4
Koehler-Stec, E.M.5
Hartnett, C.6
-
2
-
-
3042560556
-
Safety and efficacy of intra-articular injection of IL-1ra (IL-1 receptor antagonist) in patients with painful osteoarthritis of the knee: A multicenter, double blind study
-
Goupille P, Giraubeau B, Conrozier T, Marliere J, Kiefer P, Chevalier X. Safety and efficacy of intra-articular injection of IL-1ra (IL-1 receptor antagonist) in patients with painful osteoarthritis of the knee: a multicenter, double blind study [abstract]. Arthritis Rheum 2003;48 Suppl 9:S696.
-
(2003)
Arthritis Rheum
, vol.48
, Issue.SUPPL. 9
-
-
Goupille, P.1
Giraubeau, B.2
Conrozier, T.3
Marliere, J.4
Kiefer, P.5
Chevalier, X.6
-
3
-
-
3042800587
-
Phospholipases C and A2 control lysosome-mediated IL-1β secretion: Implications for inflammatory processes
-
Andrei C, Margiocco P, Poggi A, Lotti LV, Torrisi MR, Rubartelli A. Phospholipases C and A2 control lysosome-mediated IL-1β secretion: implications for inflammatory processes. Proc Natl Acad Sci U S A 2004;101:9745-50.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 9745-9750
-
-
Andrei, C.1
Margiocco, P.2
Poggi, A.3
Lotti, L.V.4
Torrisi, M.R.5
Rubartelli, A.6
-
4
-
-
1642285783
-
NALP3 forms an IL-1β processing inflammasome with increased activity in Muckle-Wells auto-inflammatory disorder
-
Agostini L, Martinon F, Burns K, McDermott MF, Hawkins PN. Tschopp J. NALP3 forms an IL-1β processing inflammasome with increased activity in Muckle-Wells auto-inflammatory disorder. Immunity 2004;20:319-25.
-
(2004)
Immunity
, vol.20
, pp. 319-325
-
-
Agostini, L.1
Martinon, F.2
Burns, K.3
McDermott, M.F.4
Hawkins, P.N.5
Tschopp, J.6
-
5
-
-
0036899758
-
De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): A new member of the expanding family of pyrin-associated autoinflammatory diseases
-
Aksentijevich I, Nowak M, Mallah M, Chae JJ, Watford WT, Hofmann SR, et al. De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases. Arthritis Rheum 2002;46:3340-8.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 3340-3348
-
-
Aksentijevich, I.1
Nowak, M.2
Mallah, M.3
Chae, J.J.4
Watford, W.T.5
Hofmann, S.R.6
-
6
-
-
8444229328
-
Anakinra in mutation-negative NOMID/CINCA syndrome: Comment on the articles by Hawkins et al and Hoffman and Patel
-
Frenkel J, Wulffraat NM, Kuis W. Anakinra in mutation-negative NOMID/CINCA syndrome: comment on the articles by Hawkins et al and Hoffman and Patel [letter]. Arthritis Rheum 2004;0: 3738-9.
-
(2004)
Arthritis Rheum
, vol.0
, pp. 3738-3739
-
-
Frenkel, J.1
Wulffraat, N.M.2
Kuis, W.3
-
7
-
-
20844443726
-
Interleukin-1 receptor antagonist anakinra in the treatment of neonatal onset multisystem inflammatory disease
-
Dailey NJ, Aksentijeich I, Chae JJ, Wesley R, Snyder C, Magalnick M, et al. Interleukin-1 receptor antagonist anakinra in the treatment of neonatal onset multisystem inflammatory disease [abstract]. Arthritis Rheum 2004;50 Suppl 9:S440.
-
(2004)
Arthritis Rheum
, vol.50
, Issue.SUPPL. 9
-
-
Dailey, N.J.1
Aksentijeich, I.2
Chae, J.J.3
Wesley, R.4
Snyder, C.5
Magalnick, M.6
-
8
-
-
0141992897
-
Successful treatment of a patient with refractory adult-onset Still's disease with anakinra
-
Rudinskaya A, Trock DH. Successful treatment of a patient with refractory adult-onset Still's disease with anakinra. J Clin Rheumatol 2003;9:330-2.
-
(2003)
J Clin Rheumatol
, vol.9
, pp. 330-332
-
-
Rudinskaya, A.1
Trock, D.H.2
-
9
-
-
18644370644
-
Rapid, responses to anakinra in patients with refractory adult-onset Still's disease
-
Fitzgerald AA, LeClercq SA, Yan A, Homik JE, Dinarello CA. Rapid, responses to anakinra in patients with refractory adult-onset Still's disease. Arthritis Rheum 2005;52:1794-803.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1794-1803
-
-
Fitzgerald, A.A.1
Leclercq, S.A.2
Yan, A.3
Homik, J.E.4
Dinarello, C.A.5
-
10
-
-
20044396441
-
Anakinra in the treatment of adult onset Still's disease
-
Haraoui B, Bourrelle D, Kaminska E. Anakinra in the treatment of adult onset Still's disease [abstract]. Ann Rheum Dis 2004;63 Suppl 1:263.
-
(2004)
Ann Rheum Dis
, vol.63
, Issue.SUPPL. 1
, pp. 263
-
-
Haraoui, B.1
Bourrelle, D.2
Kaminska, E.3
-
11
-
-
20044390451
-
Prompt response to treatment with anakinra in adult onset Still's disease
-
Aelion JA, Odhav SK. Prompt response to treatment with anakinra in adult onset Still's disease [abstract]. Ann Rheum Dis 2004;63 Suppl 1:265.
-
(2004)
Ann Rheum Dis
, vol.63
, Issue.SUPPL. 1
, pp. 265
-
-
Aelion, J.A.1
Odhav, S.K.2
-
12
-
-
14944387115
-
Treatment of systemic onset juvenile rheumatoid arthritis with anakinra
-
Irigoyen PI, Olson J, Horn C, Ilowite NT. Treatment of systemic onset juvenile rheumatoid arthritis with anakinra [abstract]. Arthritis Rheum 2004;50 Suppl 9:S437.
-
(2004)
Arthritis Rheum
, vol.50
, Issue.SUPPL. 9
-
-
Irigoyen, P.I.1
Olson, J.2
Horn, C.3
Ilowite, N.T.4
-
13
-
-
0344823965
-
Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway
-
Shoham NG, Centola M, Mansfield E, Hull KM, Wood G, Wise CA, et al. Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway. Proc Natl Acad Sci U S A 2003;100:13501-6.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 13501-13506
-
-
Shoham, N.G.1
Centola, M.2
Mansfield, E.3
Hull, K.M.4
Wood, G.5
Wise, C.A.6
-
14
-
-
3843110981
-
Beneficial response to interleukin-1 receptor antagonist in TRAPS
-
Simon A, Bodar EJ, van der Hilst JC, van der Meer JW, Fiselier TJ, Cuppen MP, et al. Beneficial response to interleukin-1 receptor antagonist in TRAPS. Am J Med 2004;117:208-10.
-
(2004)
Am J Med
, vol.117
, pp. 208-210
-
-
Simon, A.1
Bodar, E.J.2
Van Der Hilst, J.C.3
Van Der Meer, J.W.4
Fiselier, T.J.5
Cuppen, M.P.6
-
15
-
-
1042290321
-
Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra
-
Hawkins PN, Lachmann HJ, Aganna E, McDermott MF. Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra. Arthritis Rheum 2004;50:607-12.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 607-612
-
-
Hawkins, P.N.1
Lachmann, H.J.2
Aganna, E.3
McDermott, M.F.4
-
16
-
-
8444225132
-
Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist
-
Hoffman HM, Rosengren S, Boyle DL, Cho JY, Nayar J, Mueller JL, et al. Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist. Lancet 2004;364:1779-85.
-
(2004)
Lancet
, vol.364
, pp. 1779-1785
-
-
Hoffman, H.M.1
Rosengren, S.2
Boyle, D.L.3
Cho, J.Y.4
Nayar, J.5
Mueller, J.L.6
-
17
-
-
8344261590
-
Infection, fever, and exogenous and endogenous pyrogens: Some concepts have changed
-
Dinarello CA. Infection, fever, and exogenous and endogenous pyrogens: some concepts have changed. J Endotoxin Res 2004;10: 202-22.
-
(2004)
J Endotoxin Res
, vol.10
, pp. 202-222
-
-
Dinarello, C.A.1
-
18
-
-
0029979369
-
Biological basis for interleukin-1 in disease
-
Dinarello CA. Biological basis for interleukin-1 in disease. Blood 1996;87:2095-147.
-
(1996)
Blood
, vol.87
, pp. 2095-2147
-
-
Dinarello, C.A.1
-
19
-
-
0034255127
-
-
Koetz K, Bryl E, Spickschen K, O'Fallon WM, Goronzy JJ, Weyand CM. T cell homeostasis in patients with rheumatoid arthritis. Proc Natl Acad Sci U S A 2000;97:9203-8.
-
(2000)
T Cell Homeostasis in Patients with Rheumatoid Arthritis. Proc Natl Acad Sci U S a
, vol.97
, pp. 9203-9208
-
-
Koetz, K.1
Bryl, E.2
Spickschen, K.3
O'Fallon, W.M.4
Goronzy, J.J.5
Weyand, C.M.6
-
20
-
-
22244474304
-
Soluble interleukin-1 receptor accessory protein ameliorates collagen-induced arthritis by a different mode of action from that of interleukin-1 receptor antagonist
-
Smeets RL, Joosten LA, Arntz OJ, Bennink MB, Takahashi N, Carlsen H, et al. Soluble interleukin-1 receptor accessory protein ameliorates collagen-induced arthritis by a different mode of action from that of interleukin-1 receptor antagonist. Arthritis Rheum 2005;52:2202-11.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 2202-2211
-
-
Smeets, R.L.1
Joosten, L.A.2
Arntz, O.J.3
Bennink, M.B.4
Takahashi, N.5
Carlsen, H.6
-
21
-
-
2342468669
-
Granulomatous infectious diseases associated with tumor necrosis factor antagonists
-
Wallis RS, Broder MS, Wong JY, Hanson ME, Beenhouwer DO. Granulomatous infectious diseases associated with tumor necrosis factor antagonists. Clin Infect Dis 2004;38:1261-5.
-
(2004)
Clin Infect Dis
, vol.38
, pp. 1261-1265
-
-
Wallis, R.S.1
Broder, M.S.2
Wong, J.Y.3
Hanson, M.E.4
Beenhouwer, D.O.5
-
22
-
-
0037389680
-
Anakinra, a recombinant human interleukin-1 receptor antagonist (r-metHuIL-1ra), in patients with rheumatoid arthritis: A large, international, multicenter, placebo-controlled trial
-
Fleischmann RM, Schechtman J, Bennett R, Handel ML, Burmester GR, Tesser J, et al. Anakinra, a recombinant human interleukin-1 receptor antagonist (r-metHuIL-1ra), in patients with rheumatoid arthritis: a large, international, multicenter, placebo-controlled trial. Arthritis Rheum 2003;48:927-34.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 927-934
-
-
Fleischmann, R.M.1
Schechtman, J.2
Bennett, R.3
Handel, M.L.4
Burmester, G.R.5
Tesser, J.6
-
23
-
-
17444394445
-
Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist
-
Bresnihan B, Alvaro-Gracia JM, Cobby M, Doherty M, Domljan Z, Emery P, et al. Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist. Arthritis Rheum 1998;41:2196-204.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 2196-2204
-
-
Bresnihan, B.1
Alvaro-Gracia, J.M.2
Cobby, M.3
Doherty, M.4
Domljan, Z.5
Emery, P.6
-
24
-
-
0027181936
-
Interleukin-1 type II receptor: A decoy target for IL-1 that is regulated by IL-4
-
Colotta F, Re F, Muzio M, Bertini R, Polentarutti N, Sironi M, et al. Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4. Science 1993;261:472-5.
-
(1993)
Science
, vol.261
, pp. 472-475
-
-
Colotta, F.1
Re, F.2
Muzio, M.3
Bertini, R.4
Polentarutti, N.5
Sironi, M.6
-
25
-
-
0032537506
-
Interleukin-1 receptor accessory protein interacts with the type II interleukin-1 receptor
-
Malinowsky D, Lundkvist J, Laye S, Bartfai T. Interleukin-1 receptor accessory protein interacts with the type II interleukin-1 receptor. FEBS Lett 1998;429:299-302.
-
(1998)
FEBS Lett
, vol.429
, pp. 299-302
-
-
Malinowsky, D.1
Lundkvist, J.2
Laye, S.3
Bartfai, T.4
-
26
-
-
0032534729
-
The type II IL-1 receptor interacts with the IL-1 receptor accessory protein: A novel mechanism of regulation of IL-1 responsiveness
-
Lang D, Knop J, Wesche H, Raffetseder U, Kurrle R, Boraschi D, et al. The type II IL-1 receptor interacts with the IL-1 receptor accessory protein: a novel mechanism of regulation of IL-1 responsiveness. J Immunol 1998;161:6871-7.
-
(1998)
J Immunol
, vol.161
, pp. 6871-6877
-
-
Lang, D.1
Knop, J.2
Wesche, H.3
Raffetseder, U.4
Kurrle, R.5
Boraschi, D.6
-
27
-
-
0037237908
-
The soluble form of IL-1 receptor accessory protein enhances the ability of soluble type II IL-1 receptor to inhibit IL-1 action
-
Smith DE, Hanna R, Della F, Moore H, Chen H, Farese AM, et al. The soluble form of IL-1 receptor accessory protein enhances the ability of soluble type II IL-1 receptor to inhibit IL-1 action. Immunity 2003;18:87-96.
-
(2003)
Immunity
, vol.18
, pp. 87-96
-
-
Smith, D.E.1
Hanna, R.2
Della, F.3
Moore, H.4
Chen, H.5
Farese, A.M.6
-
28
-
-
0029009910
-
Molecular cloning and characterization of a second subunit of the interleukin-1 receptor complex
-
Greenfeder SA, Nunes P, Kwee L, Labow M, Chizzonite RA, Ju G. Molecular cloning and characterization of a second subunit of the interleukin-1 receptor complex. J Biol Chem 1995;270: 13757-65.
-
(1995)
J Biol Chem
, vol.270
, pp. 13757-13765
-
-
Greenfeder, S.A.1
Nunes, P.2
Kwee, L.3
Labow, M.4
Chizzonite, R.A.5
Ju, G.6
-
29
-
-
0034657781
-
IL-1 signaling cascade in liver cells and the involvement of a soluble form of the IL-I receptor accessory protein
-
Jensen LE, Muzio M, Mantovani A, Whitehead AS. IL-1 signaling cascade in liver cells and the involvement of a soluble form of the IL-I receptor accessory protein. J Immunol 2000;164:5277-86.
-
(2000)
J Immunol
, vol.164
, pp. 5277-5286
-
-
Jensen, L.E.1
Muzio, M.2
Mantovani, A.3
Whitehead, A.S.4
-
30
-
-
0037682251
-
Expression of alternatively spliced interleukin-1 receptor accessory protein mRNAs is differentially regulated during inflammation and apoptosis
-
Jensen LE, Whitehead AS. Expression of alternatively spliced interleukin-1 receptor accessory protein mRNAs is differentially regulated during inflammation and apoptosis. Cell Signal 2003;15: 793-802.
-
(2003)
Cell Signal
, vol.15
, pp. 793-802
-
-
Jensen, L.E.1
Whitehead, A.S.2
-
31
-
-
0030961241
-
Interleukin 1 receptor antagonist (IL-1Ra) is an acute-phase protein
-
Gabay C, Smith MF, Eidlen D, Arend WP. Interleukin 1 receptor antagonist (IL-1Ra) is an acute-phase protein. J Clin Invest 1997;99:2930-40.
-
(1997)
J Clin Invest
, vol.99
, pp. 2930-2940
-
-
Gabay, C.1
Smith, M.F.2
Eidlen, D.3
Arend, W.P.4
-
32
-
-
0035671761
-
Interleukin-1β, but not interleukin-1α, is required for T-cell-dependent antibody production
-
Nakae S, Asano M, Horai R, Iwakura Y. Interleukin-1β, but not interleukin-1α, is required for T-cell-dependent antibody production. Immunology 2001;104:402-9.
-
(2001)
Immunology
, vol.104
, pp. 402-409
-
-
Nakae, S.1
Asano, M.2
Horai, R.3
Iwakura, Y.4
-
33
-
-
0035213451
-
IL-1α, but not IL-1β, is required for contact-allergen- specific T cell activation during the sensitization phase in contact hypersensitivity
-
Nakae S, Naruse-Nakajima C, Sudo K, Horai R, Asano M, Iwakura Y. IL-1α, but not IL-1β, is required for contact-allergen-specific T cell activation during the sensitization phase in contact hypersensitivity. Int Immunol 2001;13:1471-8.
-
(2001)
Int Immunol
, vol.13
, pp. 1471-1478
-
-
Nakae, S.1
Naruse-Nakajima, C.2
Sudo, K.3
Horai, R.4
Asano, M.5
Iwakura, Y.6
-
35
-
-
1442306085
-
The precursor form of IL-Ia is an intracrine proinflammatory activator of transcription
-
Werman A, Werman-Venkert R, White R, Lee JK, Werman B, Krelin Y, et al. The precursor form of IL-Ia is an intracrine proinflammatory activator of transcription. Proc Natl Acad Sci U S A 2004;101:2434-9.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 2434-2439
-
-
Werman, A.1
Werman-Venkert, R.2
White, R.3
Lee, J.K.4
Werman, B.5
Krelin, Y.6
-
36
-
-
1042278175
-
Intracellular interleukin-1α functionally interacts with histone acetyltransferase complexes
-
Buryskova M, Pospisek M, Grothey A, Simmet T, Burysek L, Intracellular interleukin-1α functionally interacts with histone acetyltransferase complexes. J Biol Chem 2004;279:4017-26.
-
(2004)
J Biol Chem
, vol.279
, pp. 4017-4026
-
-
Buryskova, M.1
Pospisek, M.2
Grothey, A.3
Simmet, T.4
Burysek, L.5
-
38
-
-
0027985033
-
Interleukin-1 induces interleukin-8 from endothelial cells by a juxacrine mechanism
-
Kaplanski G, Farnarier C, Kaplanski S, Porat R, Shapiro L, Bongrand P, et al. Interleukin-1 induces interleukin-8 from endothelial cells by a juxacrine mechanism. Blood 1994;84:4242-8.
-
(1994)
Blood
, vol.84
, pp. 4242-4248
-
-
Kaplanski, G.1
Farnarier, C.2
Kaplanski, S.3
Porat, R.4
Shapiro, L.5
Bongrand, P.6
-
39
-
-
0034677174
-
Arterial inflammation in mice lacking the interleukin 1 receptor antagonist gene
-
Nicklin MJ, Hughes DE, Barton JL, Ure JM, Duff GW. Arterial inflammation in mice lacking the interleukin 1 receptor antagonist gene. J Exp Med 2000;191:303-12.
-
(2000)
J Exp Med
, vol.191
, pp. 303-312
-
-
Nicklin, M.J.1
Hughes, D.E.2
Barton, J.L.3
Ure, J.M.4
Duff, G.W.5
-
40
-
-
0034677123
-
Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice
-
Horai R, Saijo S, Tanioka H, Nakae S, Sudo K, Okahara A, et al. Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice. J Exp Med 2000;191:313-20.
-
(2000)
J Exp Med
, vol.191
, pp. 313-320
-
-
Horai, R.1
Saijo, S.2
Tanioka, H.3
Nakae, S.4
Sudo, K.5
Okahara, A.6
-
41
-
-
0030039524
-
Recombinant human interleukin-1 receptor type I in the treatment of patients with active rheumatoid arthritis
-
Drevlow BE, Lovis R, Haag MA, Sinacore JM, Jacobs C, Blosche C, et al. Recombinant human interleukin-1 receptor type I in the treatment of patients with active rheumatoid arthritis. Arthritis Rheum 1996;39:257-65.
-
(1996)
Arthritis Rheum
, vol.39
, pp. 257-265
-
-
Drevlow, B.E.1
Lovis, R.2
Haag, M.A.3
Sinacore, J.M.4
Jacobs, C.5
Blosche, C.6
-
42
-
-
0029796138
-
Effects of recombinant soluble type I interleukin-1 receptor on human inflammatory responses to endotoxin
-
Preas HL II, Reda D, Tropea M, Vandivier RW, Banks SM, Agosti JM, et al. Effects of recombinant soluble type I interleukin-1 receptor on human inflammatory responses to endotoxin. Blood 1996;88:2465-72.
-
(1996)
Blood
, vol.88
, pp. 2465-2472
-
-
Preas II, H.L.1
Reda, D.2
Tropea, M.3
Vandivier, R.W.4
Banks, S.M.5
Agosti, J.M.6
|