CHOP deletion does not impact the development of diabetes but suppresses the early production of insulin autoantibody in the NOD mouse

Apoptosis

Volumn 16, Issue 4, 2011, Pages 438-448

  Satoh, T ^a   Abiru, N ^a   Kobayashi, M ^a   Zhou, H ^a   Nakamura, K ^a   Kuriya, G ^a   Nakamura, H ^a   Nagayama, Y ^a   Kawasaki, E ^b   Yamasaki, H ^a   Yu, L ^c   Eisenbarth, G S ^c   Araki, E ^d   Mori, M ^e   Oyadomari, S ^f   Eguchi, K ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b NAGASAKI UNIVERSITY HOSPITAL   (Japan)

^c UNIVERSITY OF COLORADO DENVER   (United States)

^d KUMAMOTO UNIVERSITY   (Japan)

^e SOJO UNIVERSITY   (Japan)

^f UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Apoptosis; Autoantibody; CHOP; ER stress; Non obese diabetic mouse; Type 1 diabetes

Indexed keywords

GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; IMMUNOGLOBULIN G; INSULIN; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CD8+ T LYMPHOCYTE; CELL DESTRUCTION; CONTROLLED STUDY; DISEASE COURSE; ENDOPLASMIC RETICULUM STRESS; FEMALE; GENE EXPRESSION; INSULIN DEPENDENT DIABETES MELLITUS; INSULITIS; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEPLETION; UPREGULATION;

ADOPTIVE TRANSFER; ANIMALS; APOPTOSIS; AUTOANTIBODIES; CD8-POSITIVE T-LYMPHOCYTES; ENDOPLASMIC RETICULUM; GENE DELETION; GENE EXPRESSION REGULATION; IN SITU NICK-END LABELING; INSULIN; INSULIN-SECRETING CELLS; LYMPHOCYTE DEPLETION; MICE; MICE, INBRED NOD; PEROXIDASE; PREDIABETIC STATE; SPLEEN; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTOR CHOP;

MUS;

EID: 79955782921     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-011-0576-2     Document Type: Article

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