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Volumn 39, Issue 5, 1996, Pages 530-536

Cytokine-induced apoptotic cell death in a mouse pancreatic beta-cell line: Inhibition by Bcl-2

Author keywords

apoptosis; Bcl 2; cytokine; interferon ; interleukin 1; pancreatic beta cell; tumour necrosis factor

Indexed keywords

CYTOKINE; RECOMBINANT GAMMA INTERFERON; RECOMBINANT INTERLEUKIN 1BETA; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA;

EID: 9244232272     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00403299     Document Type: Article
Times cited : (126)

References (43)
  • 1
    • 0021875480 scopus 로고
    • In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetes insulitis
    • Bottazzo GF, Dean BM, McNally JM, Mackay EH, Swift PGF, Gamble DR (1985) In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetes insulitis. N Engl J Med 313:353-360
    • (1985) N Engl J Med , vol.313 , pp. 353-360
    • Bottazzo, G.F.1    Dean, B.M.2    McNally, J.M.3    Mackay, E.H.4    Swift, P.G.F.5    Gamble, D.R.6
  • 2
    • 0027361654 scopus 로고
    • Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients
    • Itoh N, Hanafusa T, Miyazaki A, et al. (1993) Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients. J Clin Invest 92:2313-2322
    • (1993) J Clin Invest , vol.92 , pp. 2313-2322
    • Itoh, N.1    Hanafusa, T.2    Miyazaki, A.3
  • 3
    • 0023779707 scopus 로고
    • Destruction of rat islet cell monolayers by cytokines: Synergistic interactions of interferon-γ, tumour necrosis factor, lymphotoxin, and interleukin-1
    • Pukel C, Baquerizo H, Rabinovitch A (1988) Destruction of rat islet cell monolayers by cytokines: synergistic interactions of interferon-γ, tumour necrosis factor, lymphotoxin, and interleukin-1. Diabetes 37: 133-136
    • (1988) Diabetes , vol.37 , pp. 133-136
    • Pukel, C.1    Baquerizo, H.2    Rabinovitch, A.3
  • 4
    • 0023784346 scopus 로고
    • IFN-γ and tumour necrosis factor-α: Cytotoxicity to murine islets of Langerhans
    • Campbell IL, Iscalo A, Harrison LC (1988) IFN-γ and tumour necrosis factor-α: cytotoxicity to murine islets of Langerhans. J Immunol 141: 2325-2329
    • (1988) J Immunol , vol.141 , pp. 2325-2329
    • Campbell, I.L.1    Iscalo, A.2    Harrison, L.C.3
  • 6
    • 0027428461 scopus 로고
    • Endogenous nitric oxide induced by interleukin-1β in rat islets of Langerhans and HIT-T15 cells causes significant DNA damage as measured by the 'comet' assay
    • Delaney CA, Green MH, Lowe JE, Green IC (1993) Endogenous nitric oxide induced by interleukin-1β in rat islets of Langerhans and HIT-T15 cells causes significant DNA damage as measured by the 'comet' assay. FEBS Lett 333: 291-295
    • (1993) FEBS Lett , vol.333 , pp. 291-295
    • Delaney, C.A.1    Green, M.H.2    Lowe, J.E.3    Green, I.C.4
  • 7
    • 0027427136 scopus 로고
    • Nitric oxide and nitric oxide synthase mRNA induction in mouse islet cells by interferon-γ plus tumour necrosis factor-α
    • Yamada K, Otabe S, Inada C, Takane N, Nonaka K (1993) Nitric oxide and nitric oxide synthase mRNA induction in mouse islet cells by interferon-γ plus tumour necrosis factor-α. Biochem Biophys Res Commun 197: 22-27
    • (1993) Biochem Biophys Res Commun , vol.197 , pp. 22-27
    • Yamada, K.1    Otabe, S.2    Inada, C.3    Takane, N.4    Nonaka, K.5
  • 8
    • 0028258386 scopus 로고
    • Mechanisms of cytokine-induced destruction of rat insulinoma cells: The role of nitric oxide
    • Suarez-Pinzon WL, Strynadka K, Schulz R, Rabinovitch A (1994) Mechanisms of cytokine-induced destruction of rat insulinoma cells: the role of nitric oxide. Endocrinology 134: 1006-1010
    • (1994) Endocrinology , vol.134 , pp. 1006-1010
    • Suarez-Pinzon, W.L.1    Strynadka, K.2    Schulz, R.3    Rabinovitch, A.4
  • 9
    • 0027231742 scopus 로고
    • Nitric oxide-mediated apoptosis in murine peritoneal macrophages
    • Albina JE, Cui S, Mateo RB, Reichner JS (1993) Nitric oxide-mediated apoptosis in murine peritoneal macrophages. J Immunol 150: 5080-5085
    • (1993) J Immunol , vol.150 , pp. 5080-5085
    • Albina, J.E.1    Cui, S.2    Mateo, R.B.3    Reichner, J.S.4
  • 11
    • 0022379447 scopus 로고
    • The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining
    • Tsujimoto Y, Gorham J, Crossman J, Jaffe E, Croce CM (1985) The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining. Science 229: 1390-1393
    • (1985) Science , vol.229 , pp. 1390-1393
    • Tsujimoto, Y.1    Gorham, J.2    Crossman, J.3    Jaffe, E.4    Croce, C.M.5
  • 12
    • 0023786047 scopus 로고
    • Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
    • Vaux DL, Cory S, Adams JM (1988) Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 335: 440-442
    • (1988) Nature , vol.335 , pp. 440-442
    • Vaux, D.L.1    Cory, S.2    Adams, J.M.3
  • 13
    • 0026454763 scopus 로고
    • Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene
    • Garcia I, Martinou I, Tsujimoto Y, Martinou JC (1992) Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene. Science 258: 302-304
    • (1992) Science , vol.258 , pp. 302-304
    • Garcia, I.1    Martinou, I.2    Tsujimoto, Y.3    Martinou, J.C.4
  • 14
    • 0025255538 scopus 로고
    • Deregulated bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines
    • Nunez G, London L, Hockenbery D, Alexander M, McKearn JP (1990) Deregulated bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines. J Immunol 144: 3602-3610
    • (1990) J Immunol , vol.144 , pp. 3602-3610
    • Nunez, G.1    London, L.2    Hockenbery, D.3    Alexander, M.4    McKearn, J.P.5
  • 15
    • 0025939204 scopus 로고
    • Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease
    • Strasser A, Whittingham S, Vaux DL, et al. (1991) Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease. Proc Natl Acad Sci USA 88: 8661-8665
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 8661-8665
    • Strasser, A.1    Whittingham, S.2    Vaux, D.L.3
  • 16
    • 0027944004 scopus 로고
    • Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia
    • Martinou JC, Dauphin DM, Staple JK, et al. (1994) Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia. Neuron 13: 1017-1030
    • (1994) Neuron , vol.13 , pp. 1017-1030
    • Martinou, J.C.1    Dauphin, D.M.2    Staple, J.K.3
  • 17
    • 0027427492 scopus 로고
    • Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
    • Veis DJ, Sorenson CM, Shutter JR, Korsmeyer SJ (1993) Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 75: 229-240
    • (1993) Cell , vol.75 , pp. 229-240
    • Veis, D.J.1    Sorenson, C.M.2    Shutter, J.R.3    Korsmeyer, S.J.4
  • 18
    • 0028175759 scopus 로고
    • Targeted disruption of Bcl-2αβ in mice: Occurrence of gray hair, polycystic kidney disease, and lymphocytopenia
    • Nakayama K, Nakayama KI, Negishi I, Kuida K, Sawa H, Loh DY (1994) Targeted disruption of Bcl-2αβ in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia. Proc Natl Acad Sci USA 91: 3700-3704
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3700-3704
    • Nakayama, K.1    Nakayama, K.I.2    Negishi, I.3    Kuida, K.4    Sawa, H.5    Loh, D.Y.6
  • 19
    • 0028833859 scopus 로고
    • Bcl-2 deficiency in mice leads to pleiotropic abnormalities: Accelerated lymphoid cell death in thymus and spleen, polycystic kidney, hair hypopigmentation, and distorted small intestine
    • Kamada S, Shimono A, Shinto Y, et al. (1995) bcl-2 deficiency in mice leads to pleiotropic abnormalities: accelerated lymphoid cell death in thymus and spleen, polycystic kidney, hair hypopigmentation, and distorted small intestine. Cancer Research 55: 354-359
    • (1995) Cancer Research , vol.55 , pp. 354-359
    • Kamada, S.1    Shimono, A.2    Shinto, Y.3
  • 20
    • 0025835716 scopus 로고
    • Bcl-2 protein is topographically restricted in tissues characterized by apoptotic cell death
    • Hockenbery DM, Zutter M, Hickey W, Nahm M, Korsmeyer SJ (1991) Bcl-2 protein is topographically restricted in tissues characterized by apoptotic cell death. Proc Natl Acad Sci USA 88: 6961-6965
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 6961-6965
    • Hockenbery, D.M.1    Zutter, M.2    Hickey, W.3    Nahm, M.4    Korsmeyer, S.J.5
  • 21
    • 0027715083 scopus 로고
    • Expression of bcl-2 in fetal tissues suggests a role in morphogenesis
    • LeBrun DP, Warnke RA, Cleary ML (1993) Expression of bcl-2 in fetal tissues suggests a role in morphogenesis. Am J Pathol 142: 743-753
    • (1993) Am J Pathol , vol.142 , pp. 743-753
    • Lebrun, D.P.1    Warnke, R.A.2    Cleary, M.L.3
  • 22
    • 0000181874 scopus 로고
    • Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene
    • Efrat S, Linde S, Kofod H, et al. (1988) Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene. Proc Natl Acad Sci USA 85: 9037-9041
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 9037-9041
    • Efrat, S.1    Linde, S.2    Kofod, H.3
  • 23
    • 0025349639 scopus 로고
    • Proglucagon processing similar to normal islets in pancreatic α-like cell line derived from transgenic mouse tumor
    • Powers AC, Efrat S, Mojsov S, Spector D, Habener JF, Hanahan D (1990) Proglucagon processing similar to normal islets in pancreatic α-like cell line derived from transgenic mouse tumor. Diabetes 39: 406-414
    • (1990) Diabetes , vol.39 , pp. 406-414
    • Powers, A.C.1    Efrat, S.2    Mojsov, S.3    Spector, D.4    Habener, J.F.5    Hanahan, D.6
  • 24
    • 0025878776 scopus 로고
    • NIT-1, a pancreatic β-cell line established from a transgenic NOD/ Lt mouse
    • Hamaguchi K, Gaskins HR, Leiter EH (1991) NIT-1, a pancreatic β-cell line established from a transgenic NOD/ Lt mouse. Diabetes 40: 842-849
    • (1991) Diabetes , vol.40 , pp. 842-849
    • Hamaguchi, K.1    Gaskins, H.R.2    Leiter, E.H.3
  • 25
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti I, Migliorati G, Pagliacci MC, Grignani F, Riccardi C (1991) A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 139: 271-279
    • (1991) J Immunol Methods , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 26
    • 0019929362 scopus 로고
    • Hormone-induced cell death; purification and properties of thymocytes undergoing apoptosis after glucocorticoid treatment
    • Wyllie AH, Morris RG (1982) Hormone-induced cell death; purification and properties of thymocytes undergoing apoptosis after glucocorticoid treatment. Am J Pathol 109: 78-87
    • (1982) Am J Pathol , vol.109 , pp. 78-87
    • Wyllie, A.H.1    Morris, R.G.2
  • 27
    • 0026577266 scopus 로고
    • Bcl-2 confers growth and survival advantage to interleukin 7-dependent early pre-B cells which become factor independent by a multistep process in culture
    • Borzillo GV, Endo K, Tsujimoto Y (1992) Bcl-2 confers growth and survival advantage to interleukin 7-dependent early pre-B cells which become factor independent by a multistep process in culture. Oncogene 7: 869-876
    • (1992) Oncogene , vol.7 , pp. 869-876
    • Borzillo, G.V.1    Endo, K.2    Tsujimoto, Y.3
  • 28
    • 0019225636 scopus 로고
    • Cell death: The significance of apoptosis
    • Wyllie AH (1980) Cell death: the significance of apoptosis. Int Rev Cytol 68: 251-307
    • (1980) Int Rev Cytol , vol.68 , pp. 251-307
    • Wyllie, A.H.1
  • 30
    • 0025817888 scopus 로고
    • Apoptosis in the nervous system in experimental allergic encephalomyelitis
    • Pender MP, Nguyen KB, McCombe PA, Kerr JFR (1991) Apoptosis in the nervous system in experimental allergic encephalomyelitis. J Neurol Sci 104: 81-87
    • (1991) J Neurol Sci , vol.104 , pp. 81-87
    • Pender, M.P.1    Nguyen, K.B.2    McCombe, P.A.3    Kerr, J.F.R.4
  • 31
    • 0028179849 scopus 로고
    • Interleukin-1β-induced nitric oxide production activates apoptosis in pancreatic RINm5F cells
    • Ankarcrona M, Dyphukt JM, Brune B, Nicotera P (1994) Interleukin-1β-induced nitric oxide production activates apoptosis in pancreatic RINm5F cells. Exp Cell Res 213: 172-177
    • (1994) Exp Cell Res , vol.213 , pp. 172-177
    • Ankarcrona, M.1    Dyphukt, J.M.2    Brune, B.3    Nicotera, P.4
  • 32
    • 0029093781 scopus 로고
    • Apoptotic cell death triggered by nitric oxide in pancreatic β-cells
    • Kaneto H, Fujii J, Seo HG, et al. (1995) Apoptotic cell death triggered by nitric oxide in pancreatic β-cells. Diabetes 44: 733-738
    • (1995) Diabetes , vol.44 , pp. 733-738
    • Kaneto, H.1    Fujii, J.2    Seo, H.G.3
  • 33
    • 0027282044 scopus 로고
    • Bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
    • Boice LH, Gonzalez-Garcia M, Postema CE, et al. (1993) bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 74: 597-608
    • (1993) Cell , vol.74 , pp. 597-608
    • Boice, L.H.1    Gonzalez-Garcia, M.2    Postema, C.E.3
  • 34
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death
    • Oltvai ZN, Milliman CL, Korsmeyer SJ (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death. Cell 74: 609-619
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 35
    • 0028847915 scopus 로고
    • Cloning and functional analysis of BAG-1: A novel Bcl-2-binding protein with anti-cell death activity
    • Takayama S, Sato T, Krajewski S, et al. (1995) Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity. Cell 80: 279-284
    • (1995) Cell , vol.80 , pp. 279-284
    • Takayama, S.1    Sato, T.2    Krajewski, S.3
  • 36
    • 0028809209 scopus 로고
    • Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces Bax and promotes cell death
    • Yang E, Zha J, Jockel J, Boice LH, Thompson CB, Korsmeyer SJ (1995) Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces Bax and promotes cell death. Cell 80: 285-291
    • (1995) Cell , vol.80 , pp. 285-291
    • Yang, E.1    Zha, J.2    Jockel, J.3    Boice, L.H.4    Thompson, C.B.5    Korsmeyer, S.J.6
  • 37
    • 0028946015 scopus 로고
    • Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19 K
    • Farrow SN, White JHM, Martinou I, et al. (1995) Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19 K. Nature 374: 731-733
    • (1995) Nature , vol.374 , pp. 731-733
    • Farrow, S.N.1    White, J.H.M.2    Martinou, I.3
  • 38
    • 0028986876 scopus 로고
    • Induction of apoptosis by the Bcl-2 homologue Bak
    • Chittenden T, Harrington EA, O'Connor R, et al. (1995) Induction of apoptosis by the Bcl-2 homologue Bak. Nature 374: 733-736
    • (1995) Nature , vol.374 , pp. 733-736
    • Chittenden, T.1    Harrington, E.A.2    O'Connor, R.3
  • 39
    • 0028904163 scopus 로고
    • Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak
    • Kiefer MC, Brauer MJ, Powers VC, et al. (1995) Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak. Nature 374: 736-739
    • (1995) Nature , vol.374 , pp. 736-739
    • Kiefer, M.C.1    Brauer, M.J.2    Powers, V.C.3
  • 41
    • 0028110928 scopus 로고
    • Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity
    • Kagi D, Vignaux F, Ledermann B, et al. (1994) Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity. Science 265: 528-530
    • (1994) Science , vol.265 , pp. 528-530
    • Kagi, D.1    Vignaux, F.2    Ledermann, B.3
  • 42
    • 0027161158 scopus 로고
    • Effect of bcl-2 on Fas antigen-mediated cell death
    • Itoh N, Tsujimoto Y, Nagata S (1993) Effect of bcl-2 on Fas antigen-mediated cell death. J Immunol 151: 621-627
    • (1993) J Immunol , vol.151 , pp. 621-627
    • Itoh, N.1    Tsujimoto, Y.2    Nagata, S.3


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