-
1
-
-
0018841766
-
Breeding of a non-obese diabetic strain of mice
-
Makino, S., K. Kunimoto, Y. Muraoka, Y. Mizushima, K. Katagiri, and Y. Tochino. 1980. Breeding of a non-obese diabetic strain of mice. Exp. Anim. (Tokyo). 29:1-13.
-
(1980)
Exp. Anim. (Tokyo)
, vol.29
, pp. 1-13
-
-
Makino, S.1
Kunimoto, K.2
Muraoka, Y.3
Mizushima, Y.4
Katagiri, K.5
Tochino, Y.6
-
4
-
-
0026539665
-
CD8 T cells are not required for islet destruction induced by a CD4-positive islet-specific T cell clone
-
Bradley, B.J., K. Haskins, F.G. La Rosa, and K.J. Lafferty. 1992. CD8 T cells are not required for islet destruction induced by a CD4-positive islet-specific T cell clone. Diabetes. 41:1603-1608.
-
(1992)
Diabetes
, vol.41
, pp. 1603-1608
-
-
Bradley, B.J.1
Haskins, K.2
La Rosa, F.G.3
Lafferty, K.J.4
-
5
-
-
0029030964
-
T helper cell subsets in insulin-dependent diabetes
-
Katz, J.D., and C. Benoist. 1995. T helper cell subsets in insulin-dependent diabetes. Science (Wash. DC). 268:1185-1188.
-
(1995)
Science (Wash. DC)
, vol.268
, pp. 1185-1188
-
-
Katz, J.D.1
Benoist, C.2
-
6
-
-
0025553819
-
Flow cytometric enumeration of mononuclear cell populations infiltrating the islets of Langerhans in prediabetic NOD mice: Development of a model of autoimmune insulitis for type 1 diabetes
-
Jarpe, A.J., M.R. Hickman, J.T. Anderson, W.E. Winter, and A.B. Peck. 1991. Flow cytometric enumeration of mononuclear cell populations infiltrating the islets of Langerhans in prediabetic NOD mice: development of a model of autoimmune insulitis for type 1 diabetes. Reg. Immunol. 3: 305-317.
-
(1991)
Reg. Immunol.
, vol.3
, pp. 305-317
-
-
Jarpe, A.J.1
Hickman, M.R.2
Anderson, J.T.3
Winter, W.E.4
Peck, A.B.5
-
7
-
-
0021875480
-
In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis
-
Bottazzo, G.F., B.M. Dean, J.M. McNally, E.H. MacKay, P.G.F. Swift, and D.R. Gamble. 1985. In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis. N. Engl. J. Med. 313:353-360.
-
(1985)
N. Engl. J. Med.
, vol.313
, pp. 353-360
-
-
Bottazzo, G.F.1
Dean, B.M.2
McNally, J.M.3
MacKay, E.H.4
Swift, P.G.F.5
Gamble, D.R.6
-
8
-
-
0027367830
-
Major histocompatibility complex class I molecules are required for the development of insulitis in non-obese diabetic mice
-
Katz, J., C. Benoist, and D. Mathis. 1993. Major histocompatibility complex class I molecules are required for the development of insulitis in non-obese diabetic mice. Eur. J. Immunol. 23:3358-3360.
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 3358-3360
-
-
Katz, J.1
Benoist, C.2
Mathis, D.3
-
9
-
-
0028006398
-
β2-microglobulin-deficient mice do not develop insulitis or diabetes
-
Wicker, L.S., E.H. Leiter, J.A. Todd, R.J. Renjilian, E. Peterson, P.A. Fischer, P.L. Podolin, M. Zijlstra, R. Jaenisch, and L.B. Peterson. 1994. β2-microglobulin-deficient mice do not develop insulitis or diabetes. Diabetes. 43:500-504.
-
(1994)
Diabetes
, vol.43
, pp. 500-504
-
-
Wicker, L.S.1
Leiter, E.H.2
Todd, J.A.3
Renjilian, R.J.4
Peterson, E.5
Fischer, P.A.6
Podolin, P.L.7
Zijlstra, M.8
Jaenisch, R.9
Peterson, L.B.10
-
10
-
-
0028123012
-
Prevention of insulitis and diabetes in β2-microglobulin-deficient non-obese diabetic mice
-
Sumida, T., M. Furukawa, A. Sakamoto, T. Namekawa, T. Maeda, M. Zijlstra, I. Iwamoto, T. Koike, S. Yoshida, H. Tomioka, and M. Taniguchi. 1994. Prevention of insulitis and diabetes in β2-microglobulin-deficient non-obese diabetic mice. Int. Immunol. 6:1445-1449.
-
(1994)
Int. Immunol.
, vol.6
, pp. 1445-1449
-
-
Sumida, T.1
Furukawa, M.2
Sakamoto, A.3
Namekawa, T.4
Maeda, T.5
Zijlstra, M.6
Iwamoto, I.7
Koike, T.8
Yoshida, S.9
Tomioka, H.10
Taniguchi, M.11
-
13
-
-
13344294394
-
CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells
-
Wong, F.S., I. Visintin, L. Wen, R.A. Flavell, and C.A. Janeway. 1996. CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells. J. Exp. Med. 183:67-76.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 67-76
-
-
Wong, F.S.1
Visintin, I.2
Wen, L.3
Flavell, R.A.4
Janeway, C.A.5
-
14
-
-
0028219791
-
Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
-
Kägi, D., B. Ledermann, K. Bürki, P. Seiler, B. Odermatt, K.J. Olsen, E. Podack, R.M. Zinkernagel, and H. Hengartner. 1994. Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice. Nature (Lond.). 369:31-37.
-
(1994)
Nature (Lond.)
, vol.369
, pp. 31-37
-
-
Kägi, D.1
Ledermann, B.2
Bürki, K.3
Seiler, P.4
Odermatt, B.5
Olsen, K.J.6
Podack, E.7
Zinkernagel, R.M.8
Hengartner, H.9
-
15
-
-
0028110928
-
Fas and perform pathways as major mechanisms of T cell-mediated cytotoxicity
-
Kägi, D., F. Vignaux, B. Ledermann, K. Bürki, V. Depraetere, S. Nagata, H. Hengartner, and P. Golstein. 1994. Fas and perform pathways as major mechanisms of T cell-mediated cytotoxicity. Science (Wash. DC). 265:528-530.
-
(1994)
Science (Wash. DC)
, vol.265
, pp. 528-530
-
-
Kägi, D.1
Vignaux, F.2
Ledermann, B.3
Bürki, K.4
Depraetere, V.5
Nagata, S.6
Hengartner, H.7
Golstein, P.8
-
16
-
-
0028486130
-
Two distinct pathways of specific killing revealed by perform mutant cytotoxic T lymphocytes
-
Kojima, H., N. Shinohara, S. Hanaoka, Y. Someya-Shirota, Y. Takagaki, H. Ohno, T. Saito, T. Katayama, H. Yagita, K. Okumura, et al. 1994. Two distinct pathways of specific killing revealed by perform mutant cytotoxic T lymphocytes. Immunity. 1:357-364.
-
(1994)
Immunity
, vol.1
, pp. 357-364
-
-
Kojima, H.1
Shinohara, N.2
Hanaoka, S.3
Someya-Shirota, Y.4
Takagaki, Y.5
Ohno, H.6
Saito, T.7
Katayama, T.8
Yagita, H.9
Okumura, K.10
-
17
-
-
0027946007
-
A null mutation in the perform gene impairs cytolytic T lymphocyte- And natural killer cell-mediated cytotoxicity
-
Lowin, B., F. Beermann, A. Schmidt, and J. Tschopp. 1994. A null mutation in the perform gene impairs cytolytic T lymphocyte-and natural killer cell-mediated cytotoxicity. Proc. Natl. Acad. Sci. USA. 91:11571-11575.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 11571-11575
-
-
Lowin, B.1
Beermann, F.2
Schmidt, A.3
Tschopp, J.4
-
18
-
-
0028110345
-
Immune function in mice lacking the perform gene
-
Walsh, C.M., M. Matloubian, C.-C. Liu, R. Ueda, C.G. Kurahara, J.L. Christensen, M.T.F. Huang, J.D.-E. Young, R. Ahmed, and W.R. Clark. 1994. Immune function in mice lacking the perform gene. Proc. Natl. Acad. Sci. USA. 91:10854-10858.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 10854-10858
-
-
Walsh, C.M.1
Matloubian, M.2
Liu, C.-C.3
Ueda, R.4
Kurahara, C.G.5
Christensen, J.L.6
Huang, M.T.F.7
Young, J.D.-E.8
Ahmed, R.9
Clark, W.R.10
-
19
-
-
0025755292
-
Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice
-
Ohashi, P.S., S. Oehen, K. Bürki, H.P. Pircher, C.T. Ohashi, B. Odermatt, B. Malissen, R. Zinkernagel, and H. Hengartner. 1991. Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice. Cell. 65:305-317.
-
(1991)
Cell
, vol.65
, pp. 305-317
-
-
Ohashi, P.S.1
Oehen, S.2
Bürki, K.3
Pircher, H.P.4
Ohashi, C.T.5
Odermatt, B.6
Malissen, B.7
Zinkernagel, R.8
Hengartner, H.9
-
20
-
-
0029942839
-
Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity
-
Kägi, D., B. Odermatt, P.S. Ohashi, R.M. Zinkemagel, and H. Hengartner. 1996. Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity. J. Exp. Med. 183:2143-2152.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2143-2152
-
-
Kägi, D.1
Odermatt, B.2
Ohashi, P.S.3
Zinkemagel, R.M.4
Hengartner, H.5
-
21
-
-
0025777873
-
Genetic analysis of autoimmune type 1 diabetes mellitus in mice
-
Todd, J.A., T.J. Aitman, R.J. Cornall, S. Ghosh, J.R. Hall, C.M. Hearne, A.M. Knight, J.M. Love, M.A. McAleer, and J.B. Prins. 1991. Genetic analysis of autoimmune type 1 diabetes mellitus in mice. Nature (Lond.). 351:542-547.
-
(1991)
Nature (Lond.)
, vol.351
, pp. 542-547
-
-
Todd, J.A.1
Aitman, T.J.2
Cornall, R.J.3
Ghosh, S.4
Hall, J.R.5
Hearne, C.M.6
Knight, A.M.7
Love, J.M.8
McAleer, M.A.9
Prins, J.B.10
-
22
-
-
0021723276
-
Therapy with monoclonal antibodies by elimination of T cell subsets in vivo
-
Cobbold, S.P., A. Jayasuriya, A. Nash, T.D. Prospero, and H. Waldmann. 1984. Therapy with monoclonal antibodies by elimination of T cell subsets in vivo. Nature (Lond.). 312:548-551.
-
(1984)
Nature (Lond.)
, vol.312
, pp. 548-551
-
-
Cobbold, S.P.1
Jayasuriya, A.2
Nash, A.3
Prospero, T.D.4
Waldmann, H.5
-
23
-
-
0000443245
-
Stereological techniques for electron microscopy
-
M.A. Hayat, editor. Van Nostrand Reinhold Company, New York
-
Weibel, E.R. 1973. Stereological techniques for electron microscopy. In Principles and Techniques of Electron Microscopy. Biological Applications. Vol.3. M.A. Hayat, editor. Van Nostrand Reinhold Company, New York. 237-296.
-
(1973)
Principles and Techniques of Electron Microscopy. Biological Applications
, vol.3
, pp. 237-296
-
-
Weibel, E.R.1
-
24
-
-
0021716386
-
Promotion of spontaneous diabetes in non-obese diabetic-prone mice by cyclophosphamide
-
Harada, M., and S. Makino. 1984. Promotion of spontaneous diabetes in non-obese diabetic-prone mice by cyclophosphamide. Diabetologia. 37:604-606.
-
(1984)
Diabetologia
, vol.37
, pp. 604-606
-
-
Harada, M.1
Makino, S.2
-
25
-
-
0027168794
-
The effect of cyclophosphamide treatment on lymphocyte subsets in the nonobese diabetic mouse: A comparison of various lymphoid organs
-
Zhang, Z.L., H.M. Georgiou, and T.E. Mandel. 1993. The effect of cyclophosphamide treatment on lymphocyte subsets in the nonobese diabetic mouse: a comparison of various lymphoid organs. Autoimmunity. 15:1-10.
-
(1993)
Autoimmunity
, vol.15
, pp. 1-10
-
-
Zhang, Z.L.1
Georgiou, H.M.2
Mandel, T.E.3
-
27
-
-
0024272635
-
Administration of silica particles or anti-Lyt2 antibody prevents β-cell destruction in NOD mice given cyclophosphamide
-
Charlton, B., A. Bacelj, and T.E. Mandel. 1988. Administration of silica particles or anti-Lyt2 antibody prevents β-cell destruction in NOD mice given cyclophosphamide. Diabetes. 37:930-935.
-
(1988)
Diabetes
, vol.37
, pp. 930-935
-
-
Charlton, B.1
Bacelj, A.2
Mandel, T.E.3
-
29
-
-
0025191074
-
Genomic organization of the mouse pore-forming protein (perform) gene and localization to chromosome 10: Similarities to and differences from C9
-
Trapani, J.A., B.Y. Kwon, C.A. Kozak, C. Chintamaneni, J.D.-E. Young, and B. Dupont. 1989. Genomic organization of the mouse pore-forming protein (perform) gene and localization to chromosome 10: similarities to and differences from C9. J. Exp. Med. 171:545-557.
-
(1989)
J. Exp. Med.
, vol.171
, pp. 545-557
-
-
Trapani, J.A.1
Kwon, B.Y.2
Kozak, C.A.3
Chintamaneni, C.4
Young, J.D.-E.5
Dupont, B.6
-
30
-
-
0028922437
-
Genetic control of autoimmune diabetes in the NOD mouse
-
Wicker, L.S., J.A. Todd, and L.B. Peterson. 1995. Genetic control of autoimmune diabetes in the NOD mouse. Annu. Rep. Immunol. 13:179-200.
-
(1995)
Annu. Rep. Immunol.
, vol.13
, pp. 179-200
-
-
Wicker, L.S.1
Todd, J.A.2
Peterson, L.B.3
-
31
-
-
0024379645
-
Detection of perform and granzyme a mRNAs in infiltrating cells during LCMV infection of mice
-
Müller, C., D. Kägi, T. Aebischer, B. Odermatt, W. Held, E.R. Podack, R.M. Zinkernagel, and H. Hengartner. 1989. Detection of perform and granzyme A mRNAs in infiltrating cells during LCMV infection of mice. Eur. J. Immunol. 19: 1253-1259.
-
(1989)
Eur. J. Immunol.
, vol.19
, pp. 1253-1259
-
-
Müller, C.1
Kägi, D.2
Aebischer, T.3
Odermatt, B.4
Held, W.5
Podack, E.R.6
Zinkernagel, R.M.7
Hengartner, H.8
-
32
-
-
0006781752
-
The role of T-cells in the development of autoimmune diabetes
-
Shehadeh, N.N., and K.J. Lafferty. 1993. The role of T-cells in the development of autoimmune diabetes. Diabetes Rev. 1: 141-151.
-
(1993)
Diabetes Rev.
, vol.1
, pp. 141-151
-
-
Shehadeh, N.N.1
Lafferty, K.J.2
-
33
-
-
0027420929
-
Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells
-
Leithäuser, F., J. Dhein, G. Mechtersheimer, K. Koretz, S. Brüderlein, C. Henne, A. Schmidt, K.-M. Debatin, P.H. Krammer, and P. Möller. 1993. Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells. Lab. Invest. 69:415-429.
-
(1993)
Lab. Invest.
, vol.69
, pp. 415-429
-
-
Leithäuser, F.1
Dhein, J.2
Mechtersheimer, G.3
Koretz, K.4
Brüderlein, S.5
Henne, C.6
Schmidt, A.7
Debatin, K.-M.8
Krammer, P.H.9
Möller, P.10
-
34
-
-
0029560147
-
Expression of apoptosis-inducing CD95 (Fas/Apo-1) on human β-cells sorted by flow cytometry and cultured in vitro
-
Stassi, G., M. Todaro, P. Richiusa, M. Giordano, A. Mattina, M.S. Sbriglia, A. Lo Monte, G. Buscemi, A. Galluzo, and C. Giordano. 1995. Expression of apoptosis-inducing CD95 (Fas/Apo-1) on human β-cells sorted by flow cytometry and cultured in vitro. Transplant. Proc. 27:3271-3275.
-
(1995)
Transplant. Proc.
, vol.27
, pp. 3271-3275
-
-
Stassi, G.1
Todaro, M.2
Richiusa, P.3
Giordano, M.4
Mattina, A.5
Sbriglia, M.S.6
Lo Monte, A.7
Buscemi, G.8
Galluzo, A.9
Giordano, C.10
-
35
-
-
0030890721
-
The role of Fas in autoimmune diabetes
-
Chervonsky, A.V., Y. Wang, S. Wong, I. Visintin, R. Flavell, C.A. Janeway, and L.A. Matis. 1997. The role of Fas in autoimmune diabetes. Cell. 89:17-24.
-
(1997)
Cell
, vol.89
, pp. 17-24
-
-
Chervonsky, A.V.1
Wang, Y.2
Wong, S.3
Visintin, I.4
Flavell, R.5
Janeway, C.A.6
Matis, L.A.7
-
36
-
-
0031034933
-
Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto's thyroiditis
-
Giordano, C., G. Stassi, R. De Maria, M. Todaro, P. Richiusa, G. Papoff, G. Ruberti, M. Bagnasco, R. Testi, and A. Galluzzo. 1997. Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto's thyroiditis. Science (Wash. DC). 275:960-963.
-
(1997)
Science (Wash. DC)
, vol.275
, pp. 960-963
-
-
Giordano, C.1
Stassi, G.2
De Maria, R.3
Todaro, M.4
Richiusa, P.5
Papoff, G.6
Ruberti, G.7
Bagnasco, M.8
Testi, R.9
Galluzzo, A.10
-
37
-
-
0022445268
-
Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans
-
Bendtzen, K., T. Mandrup-Poulsen, J. Nerup, J.H. Nielsen, C.A. Dinarello, and M. Svenson. 1986. Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans. Science (Wash. DC). 232:1545-1547.
-
(1986)
Science (Wash. DC)
, vol.232
, pp. 1545-1547
-
-
Bendtzen, K.1
Mandrup-Poulsen, T.2
Nerup, J.3
Nielsen, J.H.4
Dinarello, C.A.5
Svenson, M.6
-
38
-
-
0026683354
-
Perspectives in diabetes: Does nitric oxide mediate autoimmune destruction of β-cells? Possible therapeutic interventions in IDDM
-
Corbett, J.A., and M.L. McDaniel. 1992. Perspectives in diabetes: does nitric oxide mediate autoimmune destruction of β-cells? Possible therapeutic interventions in IDDM. Diabetes. 41:897-903.
-
(1992)
Diabetes
, vol.41
, pp. 897-903
-
-
Corbett, J.A.1
McDaniel, M.L.2
-
39
-
-
0023784346
-
IFN-γ and tumor necrosis factor-α cytototoxicity to murine islets of Langerhans
-
Campbell, I.L., A. Iscaro, and L.C. Harrison. 1988. IFN-γ and tumor necrosis factor-α cytototoxicity to murine islets of Langerhans. J. Immunol. 141:2325-2329.
-
(1988)
J. Immunol.
, vol.141
, pp. 2325-2329
-
-
Campbell, I.L.1
Iscaro, A.2
Harrison, L.C.3
-
40
-
-
0023601773
-
Human necrosis factor potentiates human interleukin-1 mediated rat pancreatic β-cell cytotoxicity
-
Mandrup-Poulsen, T., K. Bendtzen, C.A. Dinarello, and J. Nerup. 1987. Human necrosis factor potentiates human interleukin-1 mediated rat pancreatic β-cell cytotoxicity. J. Immunol. 139:4077-4082.
-
(1987)
J. Immunol.
, vol.139
, pp. 4077-4082
-
-
Mandrup-Poulsen, T.1
Bendtzen, K.2
Dinarello, C.A.3
Nerup, J.4
-
41
-
-
0027990811
-
Effect of tumor necrosis factor α on insulin-dependent diabetes mellitus in NOD mice. I. the early development of autoimmunity and the diabetogenic process
-
Yang, X.-D., R. Tisch, S.M. Singer, Z.A. Cao, R.S. Liblau, R.D. Schreiber, and H.O. McDevitt. 1994. Effect of tumor necrosis factor α on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process. J. Exp. Med. 180:995-1004.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 995-1004
-
-
Yang, X.-D.1
Tisch, R.2
Singer, S.M.3
Cao, Z.A.4
Liblau, R.S.5
Schreiber, R.D.6
McDevitt, H.O.7
-
42
-
-
0031051747
-
Interferon γ is essential for destruction of β cells and development of insulin-dependent diabetes mellitus
-
von Herrath, M.G., and M.B.A. Oldstone. 1996. Interferon γ is essential for destruction of β cells and development of insulin-dependent diabetes mellitus. J. Exp. Med. 185:531-539.
-
(1996)
J. Exp. Med.
, vol.185
, pp. 531-539
-
-
Herrath, M.G.1
Oldstone, M.B.A.2
-
43
-
-
0029948898
-
Genetic absence of γ-interferon delays but does not prevent diabetes in NOD mice
-
Hultgren, B., X. Huang, N. Dybal, and T.A. Stewart. 1996. Genetic absence of γ-interferon delays but does not prevent diabetes in NOD mice. Diabetes. 45:812-817.
-
(1996)
Diabetes
, vol.45
, pp. 812-817
-
-
Hultgren, B.1
Huang, X.2
Dybal, N.3
Stewart, T.A.4
|