Transgenic overexpression of human Bcl-2 in islet β cells inhibits apoptosis but does not prevent autoimmune destruction

International Immunology

Volumn 12, Issue 1, 2000, Pages 9-17

  Allison, Janette ^a   Thomas, Helen ^a   Beck, Dianne ^a   Brady, Jamie L ^a   Lew, Andrew M ^a   Elefanty, Andrew ^a   Kosaka, Hiro ^b   Kay, Thomas W ^a   Huang, David C S ^a   Strasser, Andreas ^a  

^a ROYAL MELBOURNE HOSPITAL   (Australia)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Insulin dependent diabetes mellitus; Non obese diabetic mouse; cell death

Indexed keywords

CYTOKINE; FAS LIGAND; FREE RADICAL; PERFORIN; PROTEIN BCL 2; SERINE PROTEINASE; STAUROSPORINE; STREPTOZOCIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; CYTOTOXICITY; DISEASE COURSE; GENE OVEREXPRESSION; INSULIN DEPENDENT DIABETES MELLITUS; MALE; MOUSE; NONHUMAN; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; TRANSGENE;

EID: 0033957476     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/12.1.9     Document Type: Article

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