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Volumn 1, Issue 2, 2003, Pages 261-273

A Fully Automated [35S]GTPγS Scintillation Proximity Assay for the High-Throughput Screening of Gi-Linked G Protein-Coupled Receptors

Author keywords

[No Author keywords available]

Indexed keywords

DIAGNOSTIC AGENT; G PROTEIN COUPLED RECEPTOR; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); SULFUR;

EID: 3242779121     PISSN: 1540658X     EISSN: 15578127     Source Type: Journal    
DOI: 10.1089/15406580360545071     Document Type: Article
Times cited : (35)

References (45)
  • 2
    • 0034677966 scopus 로고    scopus 로고
    • Drug discovery: a historical perspective
    • Drews J: Drug discovery: a historical perspective. Science 2000;287:1960–1965.
    • (2000) Science , vol.287 , pp. 1960-1965
    • Drews, J.1
  • 4
    • 0035489204 scopus 로고    scopus 로고
    • Reporter-gene systems for the study of G-protein-coupled receptors
    • Hill SJ, Baker JG, Rees S: Reporter-gene systems for the study of G-protein-coupled receptors. Curr Opin Pharmacol 2001;1:526–532.
    • (2001) Curr Opin Pharmacol , vol.1 , pp. 526-532
    • Hill, S.J.1    Baker, J.G.2    Rees, S.3
  • 5
    • 19644375284 scopus 로고    scopus 로고
    • FLIPR: a new instrument for accurate, high throughput optical screening
    • Schroeder KS, Neagle BD: FLIPR: a new instrument for accurate, high throughput optical screening. J Biomol Screen 1996;1:75–80.
    • (1996) J Biomol Screen , vol.1 , pp. 75-80
    • Schroeder, K.S.1    Neagle, B.D.2
  • 7
    • 0035028127 scopus 로고    scopus 로고
    • Homogeneous cell-based fluorescence polarization assay for the direct detection of cAMP
    • Prystay L, Gagne A, Kasila P, Yeh L-A, Banks P: Homogeneous cell-based fluorescence polarization assay for the direct detection of cAMP. J Biomol Screen 2001; 6:75–82.
    • (2001) J Biomol Screen , vol.6 , pp. 75-82
    • Prystay, L.1    Gagne, A.2    Kasila, P.3    Yeh, L.-A.4    Banks, P.5
  • 9
    • 0038475045 scopus 로고    scopus 로고
    • A homogeneous enzyme fragment complementation cyclic AMP screen for GPCR agonists
    • Golla R, Seethala R: A homogeneous enzyme fragment complementation cyclic AMP screen for GPCR agonists. J Biomol Screen 2002;7:515–525.
    • (2002) J Biomol Screen , vol.7 , pp. 515-525
    • Golla, R.1    Seethala, R.2
  • 10
    • 0012132962 scopus 로고    scopus 로고
    • The cellular distribution of fluorescently labeled arrestins provides a robust, sensitive, and universal assay for screening G protein-coupled receptors
    • Oakley RH, Hudson CC, Cruickshank RD, Meyers DM, Payne RE Jr, Rhem SM, Loomis CR: The cellular distribution of fluorescently labeled arrestins provides a robust, sensitive, and universal assay for screening G protein-coupled receptors. Assay Drug Devl Technol 2002;1:21–30.
    • (2002) Assay Drug Devl Technol , vol.1 , pp. 21-30
    • Oakley, R.H.1    Hudson, C.C.2    Cruickshank, R.D.3    Meyers, D.M.4    Payne, R.E.5    Rhem, S.M.6    Loomis, C.R.7
  • 11
    • 0035951849 scopus 로고    scopus 로고
    • Calcium, calcineurin, and the control of transcription
    • Crabtree GR: Calcium, calcineurin, and the control of transcription. J Biol Chem 2001;276:2313–2316.
    • (2001) J Biol Chem , vol.276 , pp. 2313-2316
    • Crabtree, G.R.1
  • 12
    • 0036469065 scopus 로고    scopus 로고
    • Review: transcription: signal transduction of gene expression
    • Brivanlou AH, Darnell JE Jr: Review: transcription: signal transduction of gene expression. Science 2002;295:813–818.
    • (2002) Science , vol.295 , pp. 813-818
    • Brivanlou, A.H.1    Darnell, J.E.2
  • 13
    • 0032852479 scopus 로고    scopus 로고
    • CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals
    • Shaywitz AJ, Greenberg ME: CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. Annu Rev Biochem 1999;68:821–861.
    • (1999) Annu Rev Biochem , vol.68 , pp. 821-861
    • Shaywitz, A.J.1    Greenberg, M.E.2
  • 14
    • 0033021674 scopus 로고    scopus 로고
    • Chimaeric Gα proteins: their potential use in drug discovery
    • Milligan G, Rees S: Chimaeric Gα proteins: their potential use in drug discovery. Trends Pharmacol Sci 1999;20:118–124.
    • (1999) Trends Pharmacol Sci , vol.20 , pp. 118-124
    • Milligan, G.1    Rees, S.2
  • 15
    • 0033956330 scopus 로고    scopus 로고
    • Insights into ligand pharmacology using receptor-G-protein fusion proteins
    • Milligan G: Insights into ligand pharmacology using receptor-G-protein fusion proteins. Trends Pharmacol Sci 2000;21:24–28.
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 24-28
    • Milligan, G.1
  • 18
    • 0035311495 scopus 로고    scopus 로고
    • Fluorescent BODIPY-GTP analogs: real-time measurements of nucleotide binding to G proteins
    • McEwen DP, Gee KR, Kang HC, Neubig RR: Fluorescent BODIPY-GTP analogs: real-time measurements of nucleotide binding to G proteins. Anal Biochem 2001;291:109–117.
    • (2001) Anal Biochem , vol.291 , pp. 109-117
    • McEwen, D.P.1    Gee, K.R.2    Kang, H.C.3    Neubig, R.R.4
  • 19
    • 0037107007 scopus 로고    scopus 로고
    • Novel detection strategies for drug discovery
    • Hemmila I, Hurskainen P: Novel detection strategies for drug discovery. Drug Discovery Today 2002;7:S150–S156.
    • (2002) Drug Discovery Today , vol.7 , pp. S150-S156
    • Hemmila, I.1    Hurskainen, P.2
  • 20
    • 0027525822 scopus 로고
    • Pharmacological characterisation of guanine-nucleotide exchange reactions in membranes from CHO cells stably transfected with human muscarinic receptors M1-M4
    • Lazareno S, Farries T, Birdsall NJM: Pharmacological characterisation of guanine-nucleotide exchange reactions in membranes from CHO cells stably transfected with human muscarinic receptors M1-M4. Life Sci 1993;52:449–456.
    • (1993) Life Sci , vol.52 , pp. 449-456
    • Lazareno, S.1    Farries, T.2    Birdsall, N.J.M.3
  • 23
    • 85018918159 scopus 로고    scopus 로고
    • 35S]GTPγS binding by scintillation proximity assay (SPA)
    • 35S]GTPγS binding by scintillation proximity assay (SPA). Proximity News 1996;25.
    • (1996) Proximity News , pp. 25
  • 24
    • 0036468067 scopus 로고    scopus 로고
    • Detection of glucagon-dependent GTPγS binding in high-throughput format
    • Dallas-Yang Q, Qureshi SA, Xie D, Zhang BB, Jiang G: Detection of glucagon-dependent GTPγS binding in high-throughput format. Anal Biochem 2002;301:156–159.
    • (2002) Anal Biochem , vol.301 , pp. 156-159
    • Dallas-Yang, Q.1    Qureshi, S.A.2    Xie, D.3    Zhang, B.B.4    Jiang, G.5
  • 26
    • 0032586641 scopus 로고    scopus 로고
    • 35S]guanosine-5′-O-(3-thio)triphosphate binding mediated by cholinergic muscarinic receptors in membranes from Chinese hamster ovary cells and rat striatum using anti-G protein scintillation proximity assay
    • 35S]guanosine-5′-O-(3-thio)triphosphate binding mediated by cholinergic muscarinic receptors in membranes from Chinese hamster ovary cells and rat striatum using anti-G protein scintillation proximity assay. J Pharmacol Exp Ther 1999;289:946–955.
    • (1999) J Pharmacol Exp Ther , vol.289 , pp. 946-955
    • DeLapp, N.W.1    McKinzie, J.H.2    Sawyer, B.D.3    Vandergriff, A.4    Falcone, J.5    McClure, D.6    Felder, C.C.7
  • 27
    • 0036765530 scopus 로고    scopus 로고
    • i3 activation: conformational selection by high-efficacy agonists, and relationship to trafficking of receptor signaling
    • i3 activation: conformational selection by high-efficacy agonists, and relationship to trafficking of receptor signaling. Mol Pharmacol 2002;62:590–601.
    • (2002) Mol Pharmacol , vol.62 , pp. 590-601
    • Newman-Tancredi, A.1    Cussac, D.2    Marini, L.3    Millan, M.J.4
  • 29
  • 33
    • 0034661482 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate signalling in mammalian cells
    • Pyne S, Pyne NJ: Sphingosine 1-phosphate signalling in mammalian cells. Biochem J 2000;349:385–402.
    • (2000) Biochem J , vol.349 , pp. 385-402
    • Pyne, S.1    Pyne, N.J.2
  • 36
    • 0031553387 scopus 로고    scopus 로고
    • Nociceptin/orphanin FQ and the opioid receptor-like ORL1 receptor
    • Meunier J-C: Nociceptin/orphanin FQ and the opioid receptor-like ORL1 receptor. Eur J Pharmacol 1997;340:1–15.
    • (1997) Eur J Pharmacol , vol.340 , pp. 1-15
    • Meunier, J.-C.1
  • 37
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye staining
    • Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye staining. Anal Biochem 1976;72:248–254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 40
    • 85018926094 scopus 로고    scopus 로고
    • Preventing assay drift in the SPA G-protein coupled receptor assay
    • AmershamBiosciences: Preventing assay drift in the SPA G-protein coupled receptor assay. Proximity News 1998;51.
    • (1998) Proximity News , pp. 51
  • 42
    • 85018915772 scopus 로고    scopus 로고
    • Effect of bead settling on observed cpm and quench index parameter
    • AmershamBiosciences: Effect of bead settling on observed cpm and quench index parameter. Proximity News 1997;48.
    • (1997) Proximity News , pp. 48
  • 43
    • 0035869428 scopus 로고    scopus 로고
    • Miniaturization of a hepatitis C virus RNA polymerase assay using a — 102°C cooled CCD camera-based imaging system
    • Zheng W, Carroll SS, Inglese J, Graves R, Howell L, Strulovici B: Miniaturization of a hepatitis C virus RNA polymerase assay using a — 102°C cooled CCD camera-based imaging system. Anal Biochem 2001;290:214–220.
    • (2001) Anal Biochem , vol.290 , pp. 214-220
    • Zheng, W.1    Carroll, S.S.2    Inglese, J.3    Graves, R.4    Howell, L.5    Strulovici, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.