Molecular characterization of the gerbil C5a receptor and identification of a transmembrane domain V amino acid that is crucial for small molecule antagonist interaction

Journal of Biological Chemistry

Volumn 280, Issue 49, 2005, Pages 40617-40623

  Waters, Stephen M ^a   Brodbeck, Robbin M ^a   Steflik, Jeremy ^a   Yu, Jianying ^a   Baltazar, Carolyn ^a   Peck, Amy E ^a   Severance, Daniel ^a   Zhang, Lu Yan ^a   Currie, Kevin ^a   Chenard, Bertrand L ^a   Hutchison, Alan J ^a   Maynard, George ^a   Krause, James E ^a  

^a NEUROGEN CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CELLS; PROTEINS;

MOLECULAR CHARACTERIZATION; PCR; TRANSMEMBRANES;

AMINO ACIDS;

COMPLEMENT COMPONENT C5A RECEPTOR; COMPLEMENTARY DNA;

ARTICLE; GERBIL; HUMAN; INFLAMMATION; MACACA; MOLECULAR CLONING; MOUSE; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT; RECEPTOR AFFINITY; SITE DIRECTED MUTAGENESIS; SPECIES DIFFERENCE; WILD TYPE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING SITES; CELL MEMBRANE; CLONING, MOLECULAR; GENE EXPRESSION; GERBILLINAE; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; RATS; RECEPTOR, ANAPHYLATOXIN C5A; SEQUENCE ALIGNMENT; SPECIES SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPTOPHAN;

GERBILLINAE; MACACA; PRIMATES; RODENTIA;

EID: 28844441553     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M509245200     Document Type: Article

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