Activation of the β2-adrenergic receptor-Gα(s) complex leads to rapid depalmitoylation and inhibition of repalmitoylation of both the receptor and Gα(s)

Journal of Biological Chemistry

Volumn 274, Issue 43, 1999, Pages 31014-31019

  Loisel, Thomas P ^a,d   Ansanay, Hervé ^a   Adam, Lynda ^a   Marullo, Stefano ^b   Seifert, Roland ^c,e   Lagacé, Monique ^a   Bouvier, Michel ^a,f  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b INSTITUT COCHIN   (France)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d LABORATOIRE D ENZYMOLOGIE ET BIOCHIMIE STRUCTURALES   (France)

^e UNIVERSITY OF KANSAS   (United States)

^f UNIVERSITY OF MONTREAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; BETA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; GUANINE NUCLEOTIDE BINDING PROTEIN; HYBRID PROTEIN; ISOPRENALINE;

ANIMAL CELL; ARTICLE; CONFORMATIONAL TRANSITION; ENZYME ACTIVITY; NONHUMAN; PALMITOYLATION; PHARMACOLOGICAL STIMULATION; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION;

ANIMALS; CELL LINE; CLONING, MOLECULAR; CYANOGEN BROMIDE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HUMANS; HYDROXYLAMINE; ISOPROTERENOL; KINETICS; MACROMOLECULAR SUBSTANCES; PALMITIC ACID; PEPTIDE FRAGMENTS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTORS, ADRENERGIC, BETA-2; RECOMBINANT FUSION PROTEINS; SPODOPTERA; TRANSFECTION;

EID: 0032747133     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.43.31014     Document Type: Article

References (59)

1. Casey, P. J. (1995) Science 268, 221-225
2. Omary, M. B., and Trowbridge, I. S. (1981) J. Biol. Chem. 256, 4715-4718
3. Omary, M. B., and Trowbridge, I. S. (1981) J. Biol. Chem. 256, 12888-12892
4. Bonatti, S., Migliaccio, G., and Simons, K. (1989) J. Biol. Chem. 264, 12590-12595
5. Mouillac, B., Caron, M., Bonin, H., Dennis, M., and Bouvier, M. (1992) J. Biol. Chem. 267, 21733-21737
6. Ng, G. Y. K., Mouillac, B., George, S. R., Caron, M., Dennis, M., Bouvier, M., and O'Dowd, B. F. (1994) Eur. J. Pharmacol. 267, 7-19
7. Loisel, T. P., Adam, L., Hebert, T., and Bouvier, M. (1996) Biochemistry 35, 15923-15932
8. Jones, T. L., Degtyarev, M. Y., and Backlund, P. S., Jr. (1997) Biochemistry 36, 7185-7191
9. Hayashi, M, K., and Haga, T. (1997) Arch. Biochem. Biophys. 340, 376-382
10. Mumby, S. M., Kleuss, C., and Gilman, A. G. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 2800-2804
11. Degtyarev, M. Y., Spiegel, A. M., and Jones, T. L. Z. (1993) J. Biol. Chem. 268, 23769-23772
12. Wedegaertner, P. B., and Bourne, H. R. (1994) Cell 77, 1063-1070
13. Kennedy, M. E., and Limbird, L. E. (1994) J. Biol. Chem. 269, 31915-31922
14. Ng, G. Y. K., O'Dowd, B. F., Caron, M., Dennis, M., Brann, M. R., and George, S. R. (1994) J. Neurochem. 63, 1589-1595
15. Grassie, M. A., McCallum, J. F., Guzzi, F., Magee, A. I., Milligan, G., and Parenti, M. (1994) Biochem. J. 302, 913-920
16. McCallum, J. F., Wise, A., Grassie, M. A., Magee, A. I., Guzzi, F., Parenti, M., and Milligan, G. (1995) Biochem. J. 310, 1021-1027
17. Wedegaertner, P. B., Chu, D. H., Wilson, P. T., Levis, M. J., and Bourne, H. R. (1993) J. Biol. Chem. 268, 25001-25008
18. Morales, J., Fishburn, C. S., Wilson, P. T., and Bourne, H. R. (1998) Mol. Biol. Cell 9, 1-14
19. Iiri, T., Backlund, P. S., Jones, T. L. Z., Wedegaertner, P. B., and Bourne, H. R. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 14592-14597
20. O'Dowd, B. F., Hnatowitch, M., Caron, M. G., Lefkowitz, R. J., and Bouvier, M. (1989) J. Biol. Chem. 264, 7564-7569
21. Jensen, A. A., Pederson, U. B., Kiemer, A., Din, N., and Anderson, P. H. (1995) J. Neurochem. 66, 1325-1331
22. Horstmeyer, A., Cramer, H., Sauer, T., Muller-Esterl, W., and Schroeder, C. (1996) J. Biol. Chem. 271, 20811-20819
23. Okamoto, Y., Ninomiya, H., Tanioka, M., Sakamoto, A., Miwa, S., and Masaki, T. (1997) J. Biol. Chem. 272, 21589-21596
24. Schülein, R., Liebenhoff, U., Muller, H., Birnbaumer, M., and Rosenthal, W. (1996) Biochem. J. 313, 611-616
25. Kawate, N., and Menon, K. M. J. (1994) J. Biol. Chem. 269, 30651-30658
26. Eason, M. G., Jacinto, M. T., Theiss, C. T., and Liggett, S. B. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 11178-11182
27. Moffett, S., Adam, L., Bonin, H., Loisel, T. P., Bouvier, M., and Mouillac, B. (1996) J. Biol. Chem. 271, 21490-21497
28. Karnik, S. S., Ridge, K. D., Bhattacharya, S., and Khorana, H. G. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 40-44
29. Linder, M. E., Middleton, P., Hepler, J. R., Taussig, R., Gilman, A. G., and Mumby, S. M. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 3675-3679
30. Berthiaume, L., and Resh, M. D. (1995) J. Biol. Chem. 270, 22399-22405
31. Resh, M. D. (1996) Cell. Signal. 8, 403-412
32. Veit, M., Sachs, K., Heckelmann, M., Maretzki, D., Hofmann, K. P., and Schmidt, M. F. (1998) Biochim. Biophys. Acta 1394, 90-98
33. Tu, Y., Wang, J., and Ross, E. M. (1997) Science 278, 1132-1135
34. Duncan, J. A., and Gilman, A. G. (1996) J. Biol. Chem. 271, 23594-23600
35. Duncan, J. A., and Gilman, A. G. (1998) J. Biol. Chem. 273, 15830-15837
36. Mumby, S. M. (1997) Curr. Opin. Cell Biol. 9, 148-154
37. Benovic, J. L., Bouvier, M., Caron, M. G., and Lefkowitz, R. J. (1988) Annu. Rev. Cell Biol. 4, 405-427
38. Bohm, S. K., Grady, E. F., and Bunnett, N. W. (1997) Biochemical J. 322, 1-18
39. Svoboda, P., and Milligan, G. (1994) Eur. J. Biochem. 224, 455-462
40. Drmota, T., Novotny, J., Kim, G. D., Eidne, K. A., Milligan, G., and Svoboda, P. (1998) J. Biol. Chem. 273, 21699-21707
41. Svoboda, P., Kim, G. D., Grassie, M. A., Eidne, K. A., and Milligan, G. (1996) Mol. Pharmacol. 49, 646-655
42. Milligan, G. (1993) Trends Pharmacol. Sci. 14, 413-418
43. van de Westerlo, E., Yang, J., Logsdon, C., and Williams, J. A. (1995) Biochem. J. 310, 559-563
44. Bertin, B., Jockers, R., Strosberg, A. D., and Marullo, S. (1997)Recept. Chann. 5, 41-51
45. Bertin, B., Freissmuth, M., Jockers, R., Strosberg, A. D., and Marullo, S. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 8827-8831
46. Seifert, R., Wenzel-Seifert, K., and Kobilka, B. K. (1999) Trends Pharmacol. Sci., in press
47. Milligan, G. (1998) Trends Endocrinol. Metab. 9, 13-19
48. Bertin, B., Strosberg, A. D., and Marullo, S. (1997) Int. J. Cancer 71, 1029-1034
49. Seifert, R., Wenzel-Seifert, K., Lee, T. W., Gether, U., Sanders-Bush, E., and Kobilka, B. K. (1998) J. Biol. Chem. 273, 5109-5116
50. Seifert, R., Lee, T. W., Lam, V. T., and Kobilka, B. K. (1998) Eur. J. Biochem. 255, 369-382
51. Graziano, M. P., Freissmuth, M., and Gilman, A. G. (1989) J. Biol. Chem. 264, 409-418
52. O'Reilly, D. R., Miller, L. K., and Luckow, V. A. (1992) Baculovirus Expression Vectors, A Laboratory Manual, W. H. Freeman and Co., New York
53. Seifert, R., Wenzel-Seifert, K., Gether, U., Lam, V. T., and Kobilka, B. K. (1999) Eur. J. Biochem. 260, 661-666
54. Benovic, J. L., Shorr, R. G. L., Caron, M. G., and Leikowitz, R. J. (1984) Biochemistry 23, 4510-4518
55. Bouvier, M., Hnatowich, M., Collins, S., Kobilka, B. K., De Blasi, A., Lefkowitz, R. J., and Caron, M. G. (1988) Mol. Pharmacol. 33, 133-139
56. Luo, K., Hurley, T. R., and Sefton, B. M. (1991) Methods Enzymol. 201, 149-152
57. Legocki, R. P., and Verma, D. P. (1981) Anal. Biochem. 111, 385-392
58. Salomon, Y., Londos, C., and Rodbell, M. (1974) Anal. Biochem. 58, 541-548
59. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254