Functional selectivity of GPCR ligand stereoisomers: New pharmacological opportunities

Molecular Pharmacology

Volumn 75, Issue 1, 2009, Pages 13-18

  Seifert, Roland ^a,b   Dove, Stefan ^a,b  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; CATECHOLAMINE DERIVATIVE; FENOTEROL; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; LIGAND; NORADRENALIN; PERTUSSIS TOXIN; PROCATEROL; SALBUTAMOL; ZINTEROL; BETA 2 ADRENERGIC RECEPTOR; DRUG;

DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; REVIEW; STEREOISOMERISM; ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CONFORMATION; DRUG EFFECT; DRUG POTENTIATION; METABOLISM; PROTEIN BINDING; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION;

BINDING SITES; EPINEPHRINE; FENOTEROL; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NOREPINEPHRINE; PHARMACEUTICAL PREPARATIONS; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, G-PROTEIN-COUPLED; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION; STEREOISOMERISM;

EID: 58849095075     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.108.052944     Document Type: Review

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