Functional coupling of the human dopamine D 2 receptor with Gα i1, Gα i2, Gα i3 and Gα o G proteins: Evidence for agonist regulation of G protein selectivity

British Journal of Pharmacology

Volumn 138, Issue 5, 2003, Pages 775-786

  Gazi, Lucien ^a   Nickolls, Sarah A ^a   Strange, Philip G ^a  

^a UNIVERSITY OF READING   (United Kingdom)

Author keywords

35S GTP S binding; 3H spiperone binding; Baculovirus expression system; Dopamine D 2 receptor; G proteins

Indexed keywords

DOPAMINE; DOPAMINE 2 RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATE; MEMBRANE RECEPTOR; PRECLAMOL; SPIPERONE; TYRAMINE;

ANIMAL CELL; ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM;

ANIMALS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GTP-BINDING PROTEIN ALPHA SUBUNIT, GI2; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEINS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; INSECTS; PROTO-ONCOGENE PROTEINS; RECEPTORS, DOPAMINE D2;

EID: 0037350667     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705116     Document Type: Article

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