Expression of dopamine D1, receptor in Sf9 insect cells and agonism of l-12-chloroscoulerine on recombinant D1 receptor

Acta Pharmacologica Sinica

Volumn 24, Issue 3, 2003, Pages 225-229

  He, You ^a   Jin, Wen Qiao ^a   Shen, Qing Xiang ^b   Chen, Xin Jian ^a   Jin, Guo Zhang ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b SHANGHAI INSTITUTE OF PLANNED PARENTHOOD RESEARCH   (China)

Author keywords

Baculoviridae; Cyclic AMP; Dopamine D1 receptors; Insects; L 12 chloroscoulerine; Recombinant proteins

Indexed keywords

12 CHLOROSCOULERINE; 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; BUTACLAMOL; COMPLEMENTARY DNA; CYCLIC AMP; DOPAMINE 1 RECEPTOR; DOPAMINE 1 RECEPTOR STIMULATING AGENT; ISOBUTYLMETHYLXANTHINE; RECOMBINANT PROTEIN; SPIPERONE; UNCLASSIFIED DRUG; 12-CHLOROSCOULERINE; BERBERINE DERIVATIVE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOGRAPHA CALIFORNICA; BACULOVIRUS; CATTLE; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG RECEPTOR BINDING; INSECT CELL; NONHUMAN; PROTEIN EXPRESSION; RECEPTOR AFFINITY; ANIMAL; ARMYWORM; BIOSYNTHESIS; CELL LINE; CYTOLOGY; DRUG POTENTIATION; GENETIC TRANSFECTION; GENETICS; METABOLISM; STEREOISOMERISM; VIROLOGY;

2,3,4,5-TETRAHYDRO-7,8-DIHYDROXY-1-PHENYL-1H-3-BENZAZEPINE; ANIMALS; BACULOVIRIDAE; BERBERINE ALKALOIDS; CELL LINE; CYCLIC AMP; RECEPTORS, DOPAMINE D1; RECOMBINANT PROTEINS; SPODOPTERA; STEREOISOMERISM; TRANSFECTION;

EID: 0037337536     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Chen LJ, Xi Y, Pang DW, Zhou QT, Jin GZ. Effect of (±)12-chloroscoulerine on brain dopamine receptors. Acta Pharmacol Sin 1996; 17: 185-9.
2. Zhang XX, Jin GZ. (-)-Stepholidine vs 12-chloroscoulerine enantiomers on firing activity of substantia nigral dopamine neurons. Acta Pharmacol Sin 1996; 17: 18-22.
3. 2 autoreceptors. Acta Pharmacol Sin 1996; 17: 477-80.
4. Chen LJ, Zhou QT, Dong ZJ, Yu LP, Jin GZ. Comparison of 12-chloroscoulerine enantiomers on animal behavior to dopamine receptors. Acta Pharmacol Sin 1999; 20: 884-8.
5. White FJ, Bednarz LM, Wachtel SR, Hjorth S, Brooderson RJ. Is stimulation of D1 and D2 receptors necessary for the expression of dopamine-mediated behavors? Pharmacol Biochem Behav 1988; 30: 189-93.
6. Buonamici M, Caccia C, Carpentieri M, Pegrassi L, Rossi AC, DiChiara G. D-1 receptor supersensitivity in rat striatum after unilateral 6-hydroxydopamine lesions. Eur J Pharmacol 1986; 126: 347-8.
7. Porceddu ML, Giorgi O, DeMontis G, Mele S, Cocco L, Ongini E, et al. 6-Hydroxydopamine-induced degeneration of nigral dopamine neurons: differential effect on nigral and striatal D-1 dopamine receptors. Life Sci 1987; 41: 697-706.
8. 1 recpetor sybtypes exhibit distinct G protein coupling behaviors in membranes from Sf9 cells. Biochemistry 1997; 36: 12930-8.
9. Jansson CC, Karp M, Oker-Blom C, Nasman J, Savola JM, Akerman KE. Two human subtypes α-C10 and αB-C2 expressed in Sf9 cells couple to transduction pathway resulting in opposite effects on cAMP production. Eur J Pharmacol 1995; 290: 75-83.
10. George ST, Arbabian MA, Ruoho AE, Kiely J, Malbon CC. High-efficiency expression of mammalian β-adrenergic receptors in baculovirus-infected insect cells. Biochem Biophys Res Commun 1989; 163: 1265-9.
11. Ng GY, Mouillac B, George SR, Caron M, Dennis M, Bouvier M, et al. Desensitization, phosphorylation and palmitoylation of the human dopamine D1 receptor. Eur J Pharmacol 1994; 267: 7-19.
12. 2 antagonistic dual actions. Trends Pharmacol Sci 2002; 23: 4-7.