Manipulating antigenic ligand strength to selectively target myelin-reactive CD4+ T cells in EAE

Journal of Neuroimmune Pharmacology

Volumn 5, Issue 2, 2010, Pages 176-188

  Sabatino Jr , Joseph J ^a   Rosenthal, Kristen M ^a   Evavold, Brian D ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Altered peptide ligands; Experimental autoimmune encephalomyelitis; Functional avidity; MHC variant peptides; SHP 1; Tolerance

Indexed keywords

ANTIGEN; BETA INTERFERON; LIGAND; MYELIN; MYELIN BASIC PROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; PEPTIDE DERIVATIVE; PROTEIN TYROSINE PHOSPHATASE SHP 1; PROTEOLIPID PROTEIN; RECEPTOR ANTIBODY; TOLL LIKE RECEPTOR;

AFFINITY CHROMATOGRAPHY; ALLERGIC ENCEPHALOMYELITIS; CD4+ T LYMPHOCYTE; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOSTIMULATION; LOW DRUG DOSE; LYMPHOCYTE ACTIVATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; ANTIBODY AFFINITY; ANTIGENS; CD4-POSITIVE T-LYMPHOCYTES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GENES, MHC CLASS I; HUMANS; LIGANDS; MYELIN SHEATH; PROTEIN BINDING; RECEPTORS, ANTIGEN, T-CELL;

EID: 77954563875     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-009-9181-3     Document Type: Review

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