-
1
-
-
0023143676
-
Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo
-
Jenkins, M. K., and R. H. Schwartz. 1987. Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo. J. Exp. Med. 165:302.
-
(1987)
J. Exp. Med.
, vol.165
, pp. 302
-
-
Jenkins, M.K.1
Schwartz, R.H.2
-
2
-
-
0030056468
-
Models of T cell anergy: Is there a common molecular mechanism?
-
Schwartz, R. H. 1996. Models of T cell anergy: is there a common molecular mechanism? J. Exp. Med. 184:1.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1
-
-
Schwartz, R.H.1
-
3
-
-
0027967385
-
Partial T cell signaling: Altered phospho-ζ and lack of zap70 recruitment in APL-induced T cell anergy
-
Sloan-Lancaster, J., A. S. Shaw, J. B. Rothbard, and P. M. Allen. 1994. Partial T cell signaling: altered phospho-ζ and lack of zap70 recruitment in APL-induced T cell anergy. Cell 79:913.
-
(1994)
Cell
, vol.79
, pp. 913
-
-
Sloan-Lancaster, J.1
Shaw, A.S.2
Rothbard, J.B.3
Allen, P.M.4
-
4
-
-
0028902752
-
Phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists
-
Madrenas, J., R. L. Wange, J. L. Wang, N. Isakov, L. E. Samelson, and R. N, Germain. 1995. ζ Phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists. Science 267:515.
-
(1995)
Science
, vol.267
, pp. 515
-
-
Madrenas, J.1
Wange, R.L.2
Wang, J.L.3
Isakov, N.4
Samelson, L.E.5
R N, G.6
-
5
-
-
0026503161
-
Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor
-
De Magistris, M. T., J. Alexander, M. Coggeshall, A. Altman, F. C. Gaeta, H. M. Grey, and A. Selte. 1992. Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor. Cell 68:625.
-
(1992)
Cell
, vol.68
, pp. 625
-
-
De Magistris, M.T.1
Alexander, J.2
Coggeshall, M.3
Altman, A.4
Gaeta, F.C.5
Grey, H.M.6
Selte, A.7
-
6
-
-
0027298445
-
Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells
-
Sloan-Lancaster, J., B. D. Evavold, and P. M. Allen. 1993. Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells. Nature 363:156.
-
(1993)
Nature
, vol.363
, pp. 156
-
-
Sloan-Lancaster, J.1
Evavold, B.D.2
Allen, P.M.3
-
7
-
-
0028025705
-
Th2 cell clonal anergy as a consequence of partial activation
-
Sloan-Lancaster, J., B. D. Evavold, and P. M. Allen. 1994. Th2 cell clonal anergy as a consequence of partial activation. J. Exp. Med. 180:1195.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1195
-
-
Sloan-Lancaster, J.1
Evavold, B.D.2
Allen, P.M.3
-
8
-
-
0027409792
-
Peptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signaling
-
Racioppi, L., F. Ronchese, L. A. Matis, and R. N. Germain. 1993. Peptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signaling. J. Exp. Med. 177:1047.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1047
-
-
Racioppi, L.1
Ronchese, F.2
Matis, L.A.3
Germain, R.N.4
-
10
-
-
0030113352
-
Responses of T cells to ligands for the T-cell receptor
-
Janeway, C. A. Jr., and K. Bottomly. 1996. Responses of T cells to ligands for the T-cell receptor. Semin. Immunol. 8:108.
-
(1996)
Semin. Immunol.
, vol.8
, pp. 108
-
-
Janeway C.A., Jr.1
Bottomly, K.2
-
11
-
-
0028913816
-
Ligands for the T-cell receptor: Hard times for avidity models
-
Janeway, C. A. 1995. Ligands for the T-cell receptor: hard times for avidity models. Immunol. Today 16:223.
-
(1995)
Immunol. Today
, vol.16
, pp. 223
-
-
Janeway, C.A.1
-
12
-
-
0029926145
-
Kinetic discrimination in T-cell activation
-
Rabinowitz, J. D., C. Beesen, D. S. Lyons, M. M. Davis, and H. M. McConnell. 1996. Kinetic discrimination in T-cell activation. Proc. Natl. Acad. Sci. USA 93:1401.
-
(1996)
Proc. Natl. Acad. Sci. Usa
, vol.93
, pp. 1401
-
-
Rabinowitz, J.D.1
Beesen, C.2
Lyons, D.S.3
Davis, M.M.4
McConnell, H.M.5
-
13
-
-
0003104975
-
A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists
-
Lyons, D. S., S. A. Lieberman, J. Hampl, J. J. Boniface, Y. Chien, L. J. Berg, and M. M. Davis. 1996. A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists. Immunity 5:53.
-
(1996)
Immunity
, vol.5
, pp. 53
-
-
Lyons, D.S.1
Lieberman, S.A.2
Hampl, J.3
Boniface, J.J.4
Chien, Y.5
Berg, L.J.6
Davis, M.M.7
-
14
-
-
0030218942
-
Altered T cell receptor ligands trigger a subset of early T cell signals
-
Rabinowitz, J. D., C. Beeson, C. Wulfing, K. Tate, P. M. Allen, M. M. Davis, and H. M. McConnell. 1996. Altered T cell receptor ligands trigger a subset of early T cell signals. Immunity 5:125.
-
(1996)
Immunity
, vol.5
, pp. 125
-
-
Rabinowitz, J.D.1
Beeson, C.2
Wulfing, C.3
Tate, K.4
Allen, P.M.5
Davis, M.M.6
McConnell, H.M.7
-
15
-
-
0030002902
-
Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy
-
Valitutti, S., S. Muller, M. Dessing, and A. Lanzavecchia. 1996. Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy. J. Exp. Med. 183:1917.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 1917
-
-
Valitutti, S.1
Muller, S.2
Dessing, M.3
Lanzavecchia, A.4
-
17
-
-
0025286210
-
Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation
-
Harding, C. V., and E. R. Unanue. 1990. Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation. Nature 346:574.
-
(1990)
Nature
, vol.346
, pp. 574
-
-
Harding, C.V.1
Unanue, E.R.2
-
18
-
-
0025182003
-
The minimal number of class II MHC-antigen complexes needed for T cell activation
-
Demotz, S., H. M. Grey, and A. Sette. 1990. The minimal number of class II MHC-antigen complexes needed for T cell activation. Science 249:1028.
-
(1990)
Science
, vol.249
, pp. 1028
-
-
Demotz, S.1
Grey, H.M.2
Sette, A.3
-
19
-
-
0030057218
-
T cell activation determined by T cell receptor number and tunable thresholds
-
Viola, A., and A. Lanzavecchia. 1996. T cell activation determined by T cell receptor number and tunable thresholds. Science 273:104.
-
(1996)
Science
, vol.273
, pp. 104
-
-
Viola, A.1
Lanzavecchia, A.2
-
20
-
-
0025741031
-
Peptide binding to class I MHC on living cells and quantitation of complexes required for CTL lysis
-
Christinck, E. R., M. A. Luscher, B. H. Barber, and D. B. Williams. 1991. Peptide binding to class I MHC on living cells and quantitation of complexes required for CTL lysis. Nature 352:67.
-
(1991)
Nature
, vol.352
, pp. 67
-
-
Christinck, E.R.1
Luscher, M.A.2
Barber, B.H.3
Williams, D.B.4
-
21
-
-
0030176270
-
Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response
-
Sykulev, Y., M. Joo, I. Vturina, T. J. Tsomides, and H. N. Eisen. 1996. Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response. Immunity 4:565.
-
(1996)
Immunity
, vol.4
, pp. 565
-
-
Sykulev, Y.1
Joo, M.2
Vturina, I.3
Tsomides, T.J.4
Eisen, H.N.5
-
22
-
-
0029027698
-
Mapping T cell recognition: The identification of a T cell receptor residue critical to the specific interaction with an influenza hemagglutinin peptide
-
Wedderbum, L. R., S. J. Searle, A. R. Rees, J. R. Lamb, and M. J. Owen. 1995. Mapping T cell recognition: the identification of a T cell receptor residue critical to the specific interaction with an influenza hemagglutinin peptide. Eur. J. Immunol. 25:1654.
-
(1995)
Eur. J. Immunol.
, vol.25
, pp. 1654
-
-
Wedderbum, L.R.1
Searle, S.J.2
Rees, A.R.3
Lamb, J.R.4
Owen, M.J.5
-
23
-
-
0033559513
-
Sodium dodecyl sulfate stability of HLA-DR1 complexes correlates with burial of hydrophobic residues in pocket 1
-
Natarajan, S., L. Stern, and S. Sadegh-Nasseri. 1999. Sodium dodecyl sulfate stability of HLA-DR1 complexes correlates with burial of hydrophobic residues in pocket 1. J. Immunol. 162:3463
-
(1999)
J. Immunol.
, vol.162
, pp. 3463
-
-
Natarajan, S.1
Stern, L.2
Sadegh-Nasseri, S.3
-
24
-
-
0030584803
-
Induction of anergy in human T helper 0 cells by stimulation with altered T cell antigen receptor ligands
-
Tsitoura, D. C., W. Holter, A. Cerwenka, C. M. Gelder, and J. R. Lamb. 1996. Induction of anergy in human T helper 0 cells by stimulation with altered T cell antigen receptor ligands. J. Immunol. 156:2801.
-
(1996)
J. Immunol.
, vol.156
, pp. 2801
-
-
Tsitoura, D.C.1
Holter, W.2
Cerwenka, A.3
Gelder, C.M.4
Lamb, J.R.5
-
25
-
-
0019916069
-
Human T-cell clones recognize chemically synthesized peptides of influenza haemagglutinin
-
Lamb, J. R., D. D. Eckels, P. Lake, J. N. Woody, and N. Green. 1982. Human T-cell clones recognize chemically synthesized peptides of influenza haemagglutinin. Nature 300:66.
-
(1982)
Nature
, vol.300
, pp. 66
-
-
Lamb, J.R.1
Eckels, D.D.2
Lake, P.3
Woody, J.N.4
Green, N.5
-
26
-
-
0027941809
-
MHC class II function preserved by low-affinity peptide interactions preceding stable binding
-
Sadegh-Nasseri, S., L. J. Stern, D. C. Wiley, and R. N. Germain. 1994. MHC class II function preserved by low-affinity peptide interactions preceding stable binding. Nature 370:647.
-
(1994)
Nature
, vol.370
, pp. 647
-
-
Sadegh-Nasseri, S.1
Stern, L.J.2
Wiley, D.C.3
Germain, R.N.4
-
27
-
-
0029037210
-
Serial triggering of many T-cell receptors by a few peptide-MHC complexes
-
Valitutti, S., S. Muller, M. Cella, E. Padovan, and A. Lanzavecchia. 1995. Serial triggering of many T-cell receptors by a few peptide-MHC complexes. Nature 375:148.
-
(1995)
Nature
, vol.375
, pp. 148
-
-
Valitutti, S.1
Muller, S.2
Cella, M.3
Padovan, E.4
Lanzavecchia, A.5
-
28
-
-
0029797674
-
Signal extinction and T cell repolarization in T helper cell-antigen-presenting cell conjugates
-
Valitutti, S., S. Muller, M. Dessing, and A. Lanzavecchia. 1996. Signal extinction and T cell repolarization in T helper cell-antigen-presenting cell conjugates. Eur. J. Immunol. 26:2012.
-
(1996)
Eur. J. Immunol.
, vol.26
, pp. 2012
-
-
Valitutti, S.1
Muller, S.2
Dessing, M.3
Lanzavecchia, A.4
-
29
-
-
0023390431
-
Molecular events in the induction of a nonresponsive state in interleukin 2-producing helper T-lymphocyte clones
-
Jenkins, M. K., D. M. Pardoll, J. Mizuguchi, T. M. Chused, and R. H. Schwartz. 1987. Molecular events in the induction of a nonresponsive state in interleukin 2-producing helper T-lymphocyte clones. Proc. Natl. Acad. Sci. USA 84:5409.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 5409
-
-
Jenkins, M.K.1
Pardoll, D.M.2
Mizuguchi, J.3
Chused, T.M.4
Schwartz, R.H.5
-
30
-
-
0029792922
-
Interleukin 2 production, not the pattern of early T-cell antigen receptor-dependent tyrosine phosphorylation, controls anergy induction by both agonists and partial agonists
-
Madrenas. J., R. H. Schwartz, and R. N. Germain. 1996. Interleukin 2 production, not the pattern of early T-cell antigen receptor-dependent tyrosine phosphorylation, controls anergy induction by both agonists and partial agonists. Proc. Natl. Acad. Sci. USA 93:9736.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9736
-
-
Madrenas, J.1
Schwartz, R.H.2
Germain, R.N.3
-
31
-
-
0024833664
-
Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation
-
Emmel, E. A., C. L. Verweij, D. B. Durand. K. M. Higgins, E. Lacy, and G. R. Crabtree. 1989. Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation. Science 246:1617.
-
(1989)
Science
, vol.246
, pp. 1617
-
-
Emmel, E.A.1
Verweij, C.L.2
Durand, D.B.3
Higgins, K.M.4
Lacy, E.5
Crabtree, G.R.6
-
32
-
-
0025893168
-
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
-
Liu, J., J. D. Farmer Jr., W. S. Lane, J. Friedman, I. Weissman, and S. L. Schreiber. 1991. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 66:807.
-
(1991)
Cell
, vol.66
, pp. 807
-
-
Liu, J.1
Farmer J.D., Jr.2
Lane, W.S.3
Friedman, J.4
Weissman, I.5
Schreiber, S.L.6
-
33
-
-
0026643141
-
Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation
-
Clipstone, N. A., and G. R. Crabtree. 1992. Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation. Nature 357:695.
-
(1992)
Nature
, vol.357
, pp. 695
-
-
Clipstone, N.A.1
Crabtree, G.R.2
-
34
-
-
0026575932
-
The mechanism of action of cyclosporin A and FK506
-
Schreiber, S. L., and G. R. Crabtree. 1992. The mechanism of action of cyclosporin A and FK506. Immunol. Today 13:136.
-
(1992)
Immunol. Today
, vol.13
, pp. 136
-
-
Schreiber, S.L.1
Crabtree, G.R.2
-
35
-
-
0025058266
-
Inhibition of antigen-specific proliferation of type 1 murine T cell clones after stimulation with immobilized anti-CD3 monoclonal antibody
-
Jenkins, M. K., C. A. Chen, G. Jung, D. L. Mueller, and R. H. Schwartz. 1990. Inhibition of antigen-specific proliferation of type 1 murine T cell clones after stimulation with immobilized anti-CD3 monoclonal antibody. J. Immunol. 144:16.
-
(1990)
J. Immunol.
, vol.144
, pp. 16
-
-
Jenkins, M.K.1
Chen, C.A.2
Jung, G.3
Mueller, D.L.4
Schwartz, R.H.5
-
36
-
-
0027333348
-
Tickling the TCR: Selective T-cell functions stimulated by altered peptide ligands
-
Evavold, B. D., J. Sloan-Lancaster, and P. M. Allen. 1993. Tickling the TCR: selective T-cell functions stimulated by altered peptide ligands. Immunol. Today 14:602.
-
(1993)
Immunol. Today
, vol.14
, pp. 602
-
-
Evavold, B.D.1
Sloan-Lancaster, J.2
Allen, P.M.3
-
37
-
-
0032192469
-
Initiation of signal transduction through the T cell receptor requires the peptide multivalent engagement of MHC ligands
-
Boniface, J., J. Rabinowitz, C. Wulfing, J. Hampl, Z. Reich, J. Altman, R. Kantor, C. Beeson, H. McConnell, and M. Davis. 1998. Initiation of signal transduction through the T cell receptor requires the peptide multivalent engagement of MHC ligands. Immunity 4:459.
-
(1998)
Immunity
, vol.4
, pp. 459
-
-
Boniface, J.1
Rabinowitz, J.2
Wulfing, C.3
Hampl, J.4
Reich, Z.5
Altman, J.6
Kantor, R.7
Beeson, C.8
McConnell, H.9
Davis, M.10
-
38
-
-
0027217789
-
Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1
-
Brown, J. H., T. S. Jardetzky, J. C. Gorga, L. J. Stem, R. G. Urban, J. L. Strominger, and D. C. Wiley. 1993. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature 364:33.
-
(1993)
Nature
, vol.364
, pp. 33
-
-
Brown, J.H.1
Jardetzky, T.S.2
Gorga, J.C.3
Stem, L.J.4
Urban, R.G.5
Strominger, J.L.6
Wiley, D.C.7
-
39
-
-
0029150969
-
Involvement of both major histocompatibility complex class II α and β chains in CD4 function indicates a role for ordered oligomerization in T cell activation
-
Konig, R., X. Shen, and R. N. Germain. 1995. Involvement of both major histocompatibility complex class II α and β chains in CD4 function indicates a role for ordered oligomerization in T cell activation. J. Exp. Med. 182:779.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 779
-
-
Konig, R.1
Shen, X.2
Germain, R.N.3
-
40
-
-
0027398938
-
Effect of T-cell receptor antagonism on interaction between T cells and antigen-presenting cells and on T-cell signaling events
-
Ruppert, J., J. Alexander, K. Snoke, M. Coggeshall, E. Herbert, D. McKenzie, H. M. Grey, and A. Sette. 1993. Effect of T-cell receptor antagonism on interaction between T cells and antigen-presenting cells and on T-cell signaling events. Proc. Natl. Acad. Sci. USA 90:2671.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 2671
-
-
Ruppert, J.1
Alexander, J.2
Snoke, K.3
Coggeshall, M.4
Herbert, E.5
McKenzie, D.6
Grey, H.M.7
Sette, A.8
-
41
-
-
0029810397
-
Early biochemical signals arise from low affinity TCR-ligand reactions at the cell-cell interface
-
Beeson, C., J. Rabinowitz, K. Tate, I. Gutgemann, Y. H. Chien, P. P. Jones, M. M. Davis, and H. M. McConnell. 1996. Early biochemical signals arise from low affinity TCR-ligand reactions at the cell-cell interface. J. Exp. Med. 184:777.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 777
-
-
Beeson, C.1
Rabinowitz, J.2
Tate, K.3
Gutgemann, I.4
Chien, Y.H.5
Jones, P.P.6
Davis, M.M.7
McConnell, H.M.8
-
42
-
-
0032493277
-
Altered peptide ligands induce quantitatively but not qualitatively different intracellular signals in primary thymocytes
-
Smyth, L. A, O. Williams, R. D. J. Huby, T. Norton, O. Acuto, S. C. Ley, and D. Kioussis. 1998. Altered peptide ligands induce quantitatively but not qualitatively different intracellular signals in primary thymocytes. Proc. Natl. Acad. Sci. USA 95:8193.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8193
-
-
Smyth, L.A.1
Williams, O.2
Huby, R.D.J.3
Norton, T.4
Acuto, O.5
Ley, S.C.6
Kioussis, D.7
-
43
-
-
0032516084
-
T cell positive selection by a high density, low affinity ligand
-
Liu, C. P., F. Crawford, P. Marrack, and J. Kappler. 1998. T cell positive selection by a high density, low affinity ligand. Proc. Natl. Acad. Sci. USA 95:4522.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 4522
-
-
Liu, C.P.1
Crawford, F.2
Marrack, P.3
Kappler, J.4
-
44
-
-
0028273017
-
Evidence for a differential avidity model of T cell selection in the thymus
-
Ashton-Rickardt, P. G., A. Bandeira, J. R. Delaney, L. Van Kaer, H. P. Pircher, R. M. Zinkernagel, and S. Tonegawa. 1994. Evidence for a differential avidity model of T cell selection in the thymus. Cell 76:651.
-
(1994)
Cell
, vol.76
, pp. 651
-
-
Ashton-Rickardt, P.G.1
Bandeira, A.2
Delaney, J.R.3
Van Kaer, L.4
Pircher, H.P.5
Zinkernagel, R.M.6
Tonegawa, S.7
|