Reduced self-reactivity of an autoreactive T cell after activation with cross-reactive non-self-ligand

Journal of Experimental Medicine

Volumn 196, Issue 9, 2002, Pages 1151-1162

  Munder, Markus ^a   Bettelli, Estelle ^a   Monney, Laurent ^a   Slavik, Jacqueline M ^b   Nicholson, Lindsay B ^a   Kuchroo, Vijay K ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c NONE   (United States)

Author keywords

Autoimmunity; Selective peripheral tolerance; Superagonist; T cell cross reactivity; T lymphocyte anergy

Indexed keywords

CD4 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 4; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE; T LYMPHOCYTE RECEPTOR; THYMIDINE; TRITIUM; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOIMMUNITY; CALCIUM TRANSPORT; CLONAL ANERGY; CROSS REACTION; ENZYME ACTIVITY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; IMMUNOLOGICAL TOLERANCE; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD3; CALCIUM; CD4-POSITIVE T-LYMPHOCYTES; CROSS REACTIONS; FEMALE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIGANDS; LYMPHOCYTE ACTIVATION; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS P21(RAS); RECEPTORS, ANTIGEN, T-CELL; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 0037020853     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20020390     Document Type: Article

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