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Volumn 160, Issue 8, 1998, Pages 3631-3636

Cutting edge: Predictable TCR antigen recognition based on peptide scans leads to the identification of agonist ligands with no sequence homology

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; HLA ANTIGEN CLASS 2; LIGAND; MYELIN BASIC PROTEIN; T LYMPHOCYTE ANTIGEN; ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; PEPTIDE; PEPTIDE FRAGMENT;

EID: 0032521903     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (129)

References (30)
  • 1
    • 0027333348 scopus 로고
    • Tickling the TCR: Selective T-cell functions stimulated by altered peptide ligands
    • Evavold, B. D., J. Sloan-Lancaster, and P. M. Allen. 1993. Tickling the TCR: selective T-cell functions stimulated by altered peptide ligands. Immunol. Today 14:602.
    • (1993) Immunol. Today , vol.14 , pp. 602
    • Evavold, B.D.1    Sloan-Lancaster, J.2    Allen, P.M.3
  • 2
    • 0028988331 scopus 로고
    • T-cell receptor antagonists and partial agonists
    • Jameson, S. C., and M. J. Bevan. 1995. T-cell receptor antagonists and partial agonists. Immunity 2:1.
    • (1995) Immunity , vol.2 , pp. 1
    • Jameson, S.C.1    Bevan, M.J.2
  • 3
    • 0028913816 scopus 로고
    • Ligands for the T-cell receptor: Hard times for avidity models
    • Janeway, C. A. 1995. Ligands for the T-cell receptor: hard times for avidity models. Immunol. Today 16:223.
    • (1995) Immunol. Today , vol.16 , pp. 223
    • Janeway, C.A.1
  • 4
    • 0030008145 scopus 로고    scopus 로고
    • Variant TCR ligands: New insights into the molecular basis of antigen-dependent signal transduction and T-cell activation
    • Madrenas, J., and R. N. Germain. 1996. Variant TCR ligands: new insights into the molecular basis of antigen-dependent signal transduction and T-cell activation. Semin. Immunol. 8:83.
    • (1996) Semin. Immunol. , vol.8 , pp. 83
    • Madrenas, J.1    Germain, R.N.2
  • 5
    • 0022375427 scopus 로고
    • Amino acid homology between the encephalitogenic site of myelin basic protein and virus: Mechanism for autoimmunity
    • Fujinami, R. S., and M. B. A. Oldstone. 1985. Amino acid homology between the encephalitogenic site of myelin basic protein and virus: mechanism for autoimmunity. Science 230:1043.
    • (1985) Science , vol.230 , pp. 1043
    • Fujinami, R.S.1    Oldstone, M.B.A.2
  • 7
    • 0027505094 scopus 로고
    • Degenerate recognition of a dissimilar antigenic peptide by myelin-basic protein-reactive T cells
    • Bhardwaj, V., V. Kumar, H. M. Geysen, and E. E. Sercarz. 1993. Degenerate recognition of a dissimilar antigenic peptide by myelin-basic protein-reactive T cells. J. Immunol. 151:5000.
    • (1993) J. Immunol. , vol.151 , pp. 5000
    • Bhardwaj, V.1    Kumar, V.2    Geysen, H.M.3    Sercarz, E.E.4
  • 8
    • 0028926223 scopus 로고
    • Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein
    • Wucherpfennig, K. W., and J. L. Strominger. 1995. Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein. Cell 80:695.
    • (1995) Cell , vol.80 , pp. 695
    • Wucherpfennig, K.W.1    Strominger, J.L.2
  • 9
    • 0029966057 scopus 로고    scopus 로고
    • Essential flexibility in the T-cell recognition of antigen
    • Kersh, G. J. Allen, P. M. 1996. Essential flexibility in the T-cell recognition of antigen. Nature 380:495.
    • (1996) Nature , vol.380 , pp. 495
    • Kersh, G.J.1    Allen, P.M.2
  • 10
    • 0028979705 scopus 로고
    • Specific T-cell recognition of minimally homologous peptides: Evidence for endogenous ligands
    • Evavold, B. D., J. Sloan-Lancaster, K. J. Wilson, J. B. Rothbard, and P. M. Allen. 1995. Specific T-cell recognition of minimally homologous peptides: evidence for endogenous ligands. Immunity 2:655.
    • (1995) Immunity , vol.2 , pp. 655
    • Evavold, B.D.1    Sloan-Lancaster, J.2    Wilson, K.J.3    Rothbard, J.B.4    Allen, P.M.5
  • 12
    • 0029855347 scopus 로고    scopus 로고
    • Structure of the complex between human T-cell receptor, viral peptide and HLA-A2
    • Garboczi, D. N., P. Ghosh, U. Utz, Q. R. Fan, W. E. Biddison, and D. C. Wiley. 1996. Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature 384:134.
    • (1996) Nature , vol.384 , pp. 134
    • Garboczi, D.N.1    Ghosh, P.2    Utz, U.3    Fan, Q.R.4    Biddison, W.E.5    Wiley, D.C.6
  • 13
    • 0030589221 scopus 로고    scopus 로고
    • Assembly, specific binding, and crystallization of a human TCR-α/β with an antigenic Tax peptide from human T lymphotropic virus type 1 and the class I MHC molecule HLA-A2
    • Garboczi, D. N., U. Utz, P. Ghosh, A. Seth, J. Kim, E. A. VanTienhoven, W. E. Biddison, and D. C. Wiley. 1996. Assembly, specific binding, and crystallization of a human TCR-α/β with an antigenic Tax peptide from human T lymphotropic virus type 1 and the class I MHC molecule HLA-A2. J. Immunol. 157:5403.
    • (1996) J. Immunol. , vol.157 , pp. 5403
    • Garboczi, D.N.1    Utz, U.2    Ghosh, P.3    Seth, A.4    Kim, J.5    VanTienhoven, E.A.6    Biddison, W.E.7    Wiley, D.C.8
  • 14
    • 0344650195 scopus 로고
    • Isolation, primary structure, and synthesis of human hypothalamic somatocrinin: Growth hormone-releasing factor
    • Ling, N., F. Esch, P. Böhlen, P. Brazeau, W. B. Wehrenberg, and R. Guillemin. 1984. Isolation, primary structure, and synthesis of human hypothalamic somatocrinin: growth hormone-releasing factor. Proc. Natl. Acad. Sci. USA 81:4302.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 4302
    • Ling, N.1    Esch, F.2    Böhlen, P.3    Brazeau, P.4    Wehrenberg, W.B.5    Guillemin, R.6
  • 16
    • 0030925578 scopus 로고    scopus 로고
    • Identification of high potency microbial and self ligands for a human autoreactive class II restricted T cell clone
    • Hemmer, B., B. Fleckenstein, M. Vergelli, G. Jung, H. McFarland, R. Martin, and K.-H. Wiesmüller. 1997. Identification of high potency microbial and self ligands for a human autoreactive class II restricted T cell clone. J. Exp. Med. 185:1651.
    • (1997) J. Exp. Med. , vol.185 , pp. 1651
    • Hemmer, B.1    Fleckenstein, B.2    Vergelli, M.3    Jung, G.4    McFarland, H.5    Martin, R.6    Wiesmüller, K.-H.7
  • 17
    • 0031569454 scopus 로고    scopus 로고
    • Modifications of peptide ligands enhancing T cell responsiveness imply large numbers of stimulatory ligands for autoreactive T cells
    • Vergelli, M., B. Hemmer, M. Kalbus, A. Vogt, N. Ling, P. Conlon, J. E. Coligan, H. F. McFarland, and R. Martin. 1997. Modifications of peptide ligands enhancing T cell responsiveness imply large numbers of stimulatory ligands for autoreactive T cells. J. Immunol. 158:3746.
    • (1997) J. Immunol. , vol.158 , pp. 3746
    • Vergelli, M.1    Hemmer, B.2    Kalbus, M.3    Vogt, A.4    Ling, N.5    Conlon, P.6    Coligan, J.E.7    McFarland, H.F.8    Martin, R.9
  • 18
    • 0029961893 scopus 로고    scopus 로고
    • Structural basis for T-cell recognition of altered peptide ligands: A single T-cell receptor can productively recognize a large continuum of related ligands
    • Kersh, G. J., and P. M. Allen. 1996. Structural basis for T-cell recognition of altered peptide ligands: a single T-cell receptor can productively recognize a large continuum of related ligands. J. Exp. Med. 184:1259.
    • (1996) J. Exp. Med. , vol.184 , pp. 1259
    • Kersh, G.J.1    Allen, P.M.2
  • 19
    • 0003104975 scopus 로고    scopus 로고
    • A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than agonists
    • Lyons, D. S., S. A. Lieberman, J. Hampl, J. J. Boniface, Y. Chien, L. J. Berg, and M. M. Davis. 1996. A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than agonists. Immunity 5:53.
    • (1996) Immunity , vol.5 , pp. 53
    • Lyons, D.S.1    Lieberman, S.A.2    Hampl, J.3    Boniface, J.J.4    Chien, Y.5    Berg, L.J.6    Davis, M.M.7
  • 20
    • 0030293628 scopus 로고    scopus 로고
    • Response of a human T cell clone to a large panel of altered peptide ligands carrying single residue substitutions in an antigenic peptide: Characterization and frequencies of TCR agonism and TCR antagonism with or without partial activation
    • Chen, Y. Z., S. Matsushita, and Y. Nishimura. 1996. Response of a human T cell clone to a large panel of altered peptide ligands carrying single residue substitutions in an antigenic peptide: characterization and frequencies of TCR agonism and TCR antagonism with or without partial activation. J. Immunol. 157:3783.
    • (1996) J. Immunol. , vol.157 , pp. 3783
    • Chen, Y.Z.1    Matsushita, S.2    Nishimura, Y.3
  • 21
    • 0027937713 scopus 로고
    • Precise prediction of major histocompatibility complex class II-peptide interaction based on peptide side chain scanning
    • Hammer, J., E. Bono, F. Gallazzi, C. Belunis, Z. Nagy, and F. Sinigaglia. 1994. Precise prediction of major histocompatibility complex class II-peptide interaction based on peptide side chain scanning. J. Exp. Med. 180:2353.
    • (1994) J. Exp. Med. , vol.180 , pp. 2353
    • Hammer, J.1    Bono, E.2    Gallazzi, F.3    Belunis, C.4    Nagy, Z.5    Sinigaglia, F.6
  • 22
    • 0030465410 scopus 로고    scopus 로고
    • Complementary mutations in an antigenic peptide allow for crossreactivity of autoreactive T-cell clones
    • Ausubel, L. J., C. K. Kwan, A. Sette, V. Kuchroo, and D. A. Hafler. 1996. Complementary mutations in an antigenic peptide allow for crossreactivity of autoreactive T-cell clones. Proc. Natl. Acad. Sci. USA 93:15317.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 15317
    • Ausubel, L.J.1    Kwan, C.K.2    Sette, A.3    Kuchroo, V.4    Hafler, D.A.5
  • 23
    • 0030989505 scopus 로고    scopus 로고
    • Peptide-independent recognition by alloreactive cytotoxic T lymphocytes (CTL)
    • Smith, P. A., A. Brunmark, M. R. Jackson, and T. A. Potter. 1997. Peptide-independent recognition by alloreactive cytotoxic T lymphocytes (CTL). J. Exp. Med. 185:1023.
    • (1997) J. Exp. Med. , vol.185 , pp. 1023
    • Smith, P.A.1    Brunmark, A.2    Jackson, M.R.3    Potter, T.A.4
  • 24
    • 0029037210 scopus 로고
    • Serial triggering of many T-cell receptors by a few peptide-MHC complexes
    • Valitutti, S., S. Müller, M. Cella, E. Padovan, and A. Lanzavecchia. 1995. Serial triggering of many T-cell receptors by a few peptide-MHC complexes. Nature 375:148.
    • (1995) Nature , vol.375 , pp. 148
    • Valitutti, S.1    Müller, S.2    Cella, M.3    Padovan, E.4    Lanzavecchia, A.5
  • 25
    • 0030057218 scopus 로고    scopus 로고
    • T cell activation determined by T-cell receptor number and tunable thresholds
    • Viola, A., and A. Lanzavecchia. 1996. T cell activation determined by T-cell receptor number and tunable thresholds. Science 273:104.
    • (1996) Science , vol.273 , pp. 104
    • Viola, A.1    Lanzavecchia, A.2
  • 26
    • 0029967743 scopus 로고    scopus 로고
    • Specificity and degeneracy of minor histocompatibility antigen-specific MHC-restricted CTL
    • Gundlach B. R., K.-H. Wiesmüller, T. Junt, S. Kienle, G. Jung, P. Walden. 1996. Specificity and degeneracy of minor histocompatibility antigen-specific MHC-restricted CTL. J. Immunol. 156:3645.
    • (1996) J. Immunol. , vol.156 , pp. 3645
    • Gundlach, B.R.1    Wiesmüller, K.-H.2    Junt, T.3    Kienle, S.4    Jung, G.5    Walden, P.6
  • 27
    • 0029764534 scopus 로고    scopus 로고
    • A mutational analysis of the binding of two different proteins to the same antibody
    • Dall'Acqua, W., E. R. Goldman, E. Eisenstein, and R. A. Mariuzza. 1996. A mutational analysis of the binding of two different proteins to the same antibody. Biochemistry 35:9667.
    • (1996) Biochemistry , vol.35 , pp. 9667
    • Dall'Acqua, W.1    Goldman, E.R.2    Eisenstein, E.3    Mariuzza, R.A.4


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