Lack of SHPTP1 results in src-family kinase hyperactivation and thymocyte hyperresponsiveness

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 18, 1996, Pages 9624-9629

  Lorenz, Ulrike ^a,c   Ravichandran, Kodimangalam S ^b,c   Burakoff, Steven J ^b   Neel, Benjamin G ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Fyn; Lck; motheaten mice; protein tyrosine phosphatase; T lymphocytes

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CELL SURFACE RECEPTOR; INTERLEUKIN 2 RECEPTOR; PROTEIN KINASE P60; PROTEIN TYROSINE PHOSPHATASE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FLOW CYTOMETRY; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; THYMOCYTE;

ANIMALS; ANTIGENS, CD4; CELL DEATH; CELL DIVISION; ENZYME ACTIVATION; FLOW CYTOMETRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C3H; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTORS, ANTIGEN, T-CELL; SHP1 PROTEIN TYROSINE PHOSPHATASE; SRC-FAMILY KINASES; T-LYMPHOCYTES; TYROSINE;

EID: 0029844309     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.18.9624     Document Type: Article

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