Oral tolerance in myelin basic protein T-cell receptor transgenic mice: Suppression of autoimmune encephalomyelitis and dose-dependent induction of regulatory cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 1, 1996, Pages 388-391

  Chen, Youhai ^a   Inobe, Jun Ichi ^a   Kuchroo, Vijay K ^a   Baron, Jody L ^b   Janeway Jr , Charles A ^b,c   Weiner, Howard L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

anergy; interleukin 4; peripheral tolerance; suppression; transforming growth factor

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; MYELIN BASIC PROTEIN; RECOMBINANT GAMMA INTERFERON; RECOMBINANT INTERLEUKIN 10; RECOMBINANT INTERLEUKIN 2; RECOMBINANT INTERLEUKIN 4; T LYMPHOCYTE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; CLONAL ANERGY; IMMUNIZATION; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SPLEEN CELL; TRANSGENIC MOUSE;

ADMINISTRATION, ORAL; ANIMALS; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; IMMUNE TOLERANCE; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-2; INTERLEUKIN-4; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYELIN BASIC PROTEINS; RECEPTORS, ANTIGEN, T-CELL; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA; MUS MUSCULUS;

EID: 0030043855     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.1.388     Document Type: Article

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