The Src-homology domain 2-bearing protein tyrosine phosphatase-1 inhibits antigen receptor-induced apoptosis of activated peripheral T cells

Journal of Immunology

Volumn 162, Issue 11, 1999, Pages 6359-6367

  Zhang, Jinyi ^a   Somani, Ally Khan ^a   Watt, Stephen ^b   Mills, Gordon B ^b   Siminovitch, Katherine A ^a,c  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c MOUNT SINAI HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FAS LIGAND; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; ENZYME ACTIVITY; IMMUNE RESPONSE; IMMUNOSTIMULATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; ENZYME ACTIVATION; IMMUNOSUPPRESSIVE AGENTS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTORS, ANTIGEN, T-CELL; SHP1 PROTEIN TYROSINE PHOSPHATASE; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; T-LYMPHOCYTES;

EID: 0033151970     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (58)

1. Ashwell, J. D., D. L. Longo, and S. Bridges. 1987. T-cell tumor elimination as a result of T-cell receptor-mediated activation. Science 237:61.
2. Smith, C. A., G. T. Williams, R. Kingston, E. J. Jenkinson, and J. J. Owen. 1989. Antibodies to CD3/T cell receptor complex induce death by apoptosis in immature T cells in thymic cultures. Nature 337:181.
3. Shi, Y., B. M. Sahai, and D. R. Green. 1989. Cyclosporin A inhibits activation-induced cell death in T cell hybridomas and in thymocytes. Nature 339:625.
4. low thymocytes in vivo. Science 250: 1720.
5. + thymocytes in suspension culture by extrathymic antigen-presenting cells. Nature 351:150.
6. Green, D. R., and D. W. Scott. 1994. Activation-induced apoptosis in lymphocytes. Curr. Opin. Immunol. 6:476.
7. Steller, H. Mechanisms and genes of cellular suicide. 1995. Science 267:1445.
8. Von Boehmer, H., H. S. Teh, and P. Kisielow. 1989. The thymus selects the useful, neglects the useless and destroys the harmful. Immunol. Today 10:57.
9. + precursor stage. Nature 334:620.
10. Pricher, H., K. Burki, R. Lang, H. Hengartner, and R. M. Zinkernagel. 1989. Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature 342:559.
11. MacDonald, H. R., and R. K. Lees. 1990. Programmed death of autoreactive thymocytes. Nature 343:642.
12. Russell, J. H., C. L. White, D. Y. Loh, and P. Meleedy-Rey. 1991. Receptor-stimulated death pathway is opened by antigen in mature T cells. Proc. Natl. Acad. Sci. USA 88:2151.
13. Kabelitz, D., T. Pohl, and K. Pechhold. 1993. Activation-induced cell death (apoptosis) of mature peripheral T lymphocytes. Immunol. Today 14:338.
14. Radvanyi, L. G., G. B. Mills, and R. G. Miller. 1993, Religation of the T cell receptor after primary activation of mature T cells inhibits proliferation and induces apoptotic cell death. J. Immunol. 150:5704.
15. Brunner, T., R. J. Mogil, D. LaFace, N. J. Yoo, A. Mahboubi, F. Echeverri, S. J. Martin, W. R. Force, D. H. Lynch, C. F. Ware, and D. R. Green. 1995. Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature 373:441.
16. Ju, S. T., D. J. Panka, H. Cui, R. Ettinger, M. el-Khatib, D. H. Sherr, B. Z. Stanger, and A. Marshak-Rothstein. 1995. Fas (CD95)/FasL interactions required for programmed cell death after T-cell activation. Nature 373:444.
17. Dhein, J., H. Walczak, C. Baumler, K. M. Debatin, and P. H. Krammer. 1995. Autocrine T-cell suicide mediated by APO-1/(Fas/CD95). Nature 373:438.
18. Lai, N. S, Y. L. Lan, C. L. Yu, and R. H. Lin. 1995. Role of tumor necrosis factor-α in the regulation of activated synovial T cell growth: down-regulation of synovial T cells in rheumatoid arthritis patients. Eur. J. Immunol. 25:3243.
19. Zheng, L., G. Fisher, R. E. Miller, J. Peschon, D. H. Lynch, and M. J. Leonardo. 1995. Induction of apoptosis in mature T cells by tumour necrosis factor. Nature 377:384.
20. Lin, R. H., Y. W. Hqang, B. C. Yang, and C. S. Lin. 1997. TNF receptor-2-triggered apoptosis is associated with the down-regulation of Bcl-xL on activated T cells and can be prevented by CD28 costimulation. J. Immunol. 158:598.
21. Alberola-Ila, J., S. Takaki, J. D. Kerner, and R. M. Perlmutter. 1997. Differential signaling by lymphocyte antigen receptors. Annu. Rev. Immunol. 15:125.
22. Lavin, M. F., D. Watters, and Q. Song. 1996. Role of protein kinase activity in apoptosis. Experientia 52:979.
23. King, L. B., and J. D. Ashwell. 1993. Signaling for death of lymphoid cells. Curr. Opin. Immunol. 5:368.
24. Orchansky, P. L., and H. S. Teh. 1994. Activation-induced cell death in proliferating T cells is associated with altered tyrosine phosphorylation of TCR/CD3 subunits. J. Immunol. 153:615.
25. lck plays a key role in transducing apoptotic signals in T cells. FEBS Lett. 363:101.
26. Migita, K., K. Eguchi, Y. Kawabe, and S. Nagataki. 1995. Tyrosine phosphorylation participates in peripheral T-cell activation and programmed cell death in vivo. Immunology 85:550.
27. Yamanashi, Y., T. Fukuda, H. Nishizumi, T. Inazu, K. Higashi, D. Kitamura, T. Ishida, H. Yamamura, T. Watanabe, and T. Yamamoto. 1997. Role of tyrosine phosphorylation of HS1 in B cell antigen receptor mediated apoptosis. J. Exp. Med. 185:1387.
28. Eischen, C. M., B. L. Williams, W. Zhang, L. E. Samelson, D. H. Lynch, and R. T. Abraham, and P. J. Leibson. 1997. Leibson ZAP70 tyrosine kinase is required for the up-regulation of Fas ligand in activation-induced T cell apoptosis. J. Immunol. 159:1135.
29. Gonzalez-Garcia, A., L. R-Borlado, E. Leonardo, I. Merida, C. Marinez-A, and A. C. Carrera. 1997. Lck is necessary and sufficient for Fas-ligand expression and apoptotic cell death in mature cycling T cells. J. Immunol. 158:4104.
30. Pani, G., and K. A. Siminovitch. 1997. Protein tyrosine phosphatase roles in the regulation of lymphocyte signaling. Clin. Immunol. Immunopathol. 84:1.
31. Pani, G., K. D. Fischer, I. Mlinari-Rascan, and K. A. Siminovitch. 1996. Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase. J. Exp. Med. 184:839.
32. Lorenz, U., K. S. Ravichandran, S. J. Burakoff, and B. G. Neel. 1996. Lack of SHPTP1 results in src-family kinase hyperactivation and thymocyte hyperresponsiveness. Proc. Natl. Acad. Sci. USA 93:9624.
33. Plas, D. R., R. Johnson, J. T. Pingel, R. J. Matthews, M. Dalton, G. Roy, A. C. Chan, and M. L. Thomas. 1996. Direct regulation of ZAP70 by SHP-1 in T cell antigen receptor signaling. Science 272:1173.
34. Musci, M. A., S. L. Beaves, S. E. Ross, T. Yi, and G. A. Koretzky. 1997. Surface expression of hemopoietic cell phosphatase fails to complement CD45 deficiency and inhibits TCR-mediated signal transduction in a Jurkat T cell clone. J. Immunol. 1158:1565.
35. lck phosphorylation and ZAP-70 binding to T cell receptor chain. Biochem. Biophys. Res. Comm. 222:50.
36. Cyster, J. G., and C. C. Goodnow. 1995. Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection. Immunity 2:13.
37. Ong, C. J., D. Chui, H. S. Teh, and J. D. Marth. 1994. Thymic CD45 tyrosine phosphatase regulates apoptosis and MHC-restricted negative selection. J. Immunol. 152:3793.
38. Klaus, S. J., S. P. Sidorenko, and E. A. Clark. 1996. CD45 ligation induces programmed cell death in T and B lymphocytes. J. Immunol. 156:2743.
39. Pani, G., K. A. Siminovitch, and C. J. Paige. 1997. The motheaten mutation rescues B cell signaling and development in CD45-deficient mice. J. Exp. Med. 186:581.
40. + T cells responding to bacterial superantigen. J. Immunol. 154:4302.
41. Kozlowski, M., I. Mlinaric-Rascan, G. S. Feng, R. Shen, A. Pawson, and K. A. Siminovitch. 1993. Expression and catalytic activity of the tyrosine phosphatase PTP1C is severely impaired in motheaten and viable motheaten mice. J. Exp. Med. 178:2157.
42. Weiss, A., and D. R. Litttnan. 1994. Signal transduction by lymphocyte antigen receptors. Cell 76:263.
43. Pani, G., M. Kozlowski, J. C. Cambier, G. B. Mills, and K. A. Siminovitch. 1995. Identification of the tyrosine phosphatase PTP1C as a B cell antigen receptor-associated protein involved in the regulation of B cell signaling. J. Exp. Med. 181:2077.
44. Su, X., T. Zhou, Z. Wang, P. Yang, R. S. Jope, and J. D. Mountz. 1995. Defective expression of hematopoietic cell protein tyrosine phosphatase (HCP) in lymphoid cell blocks Fas-mediated apoptosis. Immunity 2:353.
45. Su, X., T. Zhou, P. A. Yang, Z. Wang, and J. D. Mountz. 1996. Hematopoietic cell protein-tyrosine phosphatase-deficient motheaten mice exhibit T cell apoptosis defect. J. Immunol. 156:4198.
46. Mountz, J. D., T. Zhou, X. Su, J. Wu, and J. Cheng. 1996. The role of programmed cell death as an emerging new concept for the pathogenesis of autoimmune diseases. Clin. Immunol. Immunopathol. 80:2.
47. Siminovitch K. A., and B. G. Neel. 1998. Regulation of B cell signal transduction by SH2-containing protein tyrosine phosphatases. Semin. Immunol. 10:329.
48. Doody, G. M., L. B. Justement, C. C. Delibrias, R. J. Matthews, J. Lin, M. L. Thomas, and D. T. Fearon, 1995. A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP. Science 269:242.
49. D'Ambrosio, D., K. L. Hippen, S. A. Minskoff, I. Mellman, G. Pani, K. A. Siminovitch, and J. C. Cambier. 1995. Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by FcγRIIB1. Science 268:293.
50. Tarakhovsky, A., S. B. Kanner, J. Hombach, J. A. Ledbetter, W. Müller, N. Killeen, and K. Rajewsky. 1995. A role for CD5 in TCR-mediated signal transduction and thymocyte selection. Science 269:535.
51. Miethke, T., R. Vabulas, R. Bittlingmaier, K. Heeg, and H. Wagner. 1996. Mechanisms of peripheral T cell deletion: anergized T cells are Fas resistant but undergo proliferaiton-associated apoptosis. Eur. J. Immunol. 26:1459.
52. lck in T cell receptor/CD3-mediated apoptosis and Fas ligand induction in Jurkat cells. Biochem. Biophys. Res. Comm. 213:994.
53. Takayama, H., M. H. Lee, and Y. Shirota-Somey. 1996. Lack of requirement for SHP-1 in both Fas-mediated and perforin-mediated cell death induced by CTL. J. Immunol. 157:3943.
54. Sprent, J., D. Loh, E. Gao, and T. Ron. 1998. T cell selection in the thymus. Immunol. Rev. 101:73.
55. Ohashi, P. S. 1996. T cell selection and autoimmunity. Curr. Opin. Immunol. 8:808.
56. Rajewsky, K. 1996. Clonal selection and learning in the antibody system. Nature 381:751.
57. Kisielow, P., and J. von Boehmer. 1995. Development and selection of T cells: facts and puzzles. Adv. Immunol 58:187.
58. Liblau, R. S., R. Tisch, K. Shokat, X. Yang, N. Dumont, C. C. Goodnow, and H. O. McDevitt. 1996. Intravenous injection of soluble antigen induces thymic and peripheral T cell apoptosis. Proc. Natl. Acad. Sci. USA 93:3031.