-
1
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate
-
Li, J., C. Yen, D. Liaw, K. Podsypanina, S. Bose, S. I. Wang, J. Puc, C. Miliaresis, L. Rodgers, R. McCombie, et al. 1997. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate. Science 275:1943.
-
(1997)
Science
, vol.275
, pp. 1943
-
-
Li, J.1
Yen, C.2
Liaw, D.3
Podsypanina, K.4
Bose, S.5
Wang, S.I.6
Puc, J.7
Miliaresis, C.8
Rodgers, L.9
McCombie, R.10
-
2
-
-
0031001041
-
TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor β
-
Li, D. M., and H. Sun. 1997. TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor β. Cancer Res. 57:2124.
-
(1997)
Cancer Res.
, vol.57
, pp. 2124
-
-
Li, D.M.1
Sun, H.2
-
3
-
-
17144436629
-
Identification of a candidate tumor suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
-
Steck, P. A., M. A. Pershouse, S. A. Jasser, W. K. A. Yung, H. Lin, A. H. Ligon, L. A. Langford, M. L. Baumgard, T. Hattier, T. Davis, et al. 1997. Identification of a candidate tumor suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nut. Genet. 15:356.
-
(1997)
Nut. Genet.
, vol.15
, pp. 356
-
-
Steck, P.A.1
Pershouse, M.A.2
Jasser, S.A.3
Yung, W.K.A.4
Lin, H.5
Ligon, A.H.6
Langford, L.A.7
Baumgard, M.L.8
Hattier, T.9
Davis, T.10
-
4
-
-
0026483761
-
Recurrent abnormalities of chromosome bands 10q23-25 in non-Hodgkin's lymphoma
-
Speaks, S. L., W. G. Sanger, A. S. Masih, D. S. Harrington, M. Hess, and J. O. Armitage. 1992. Recurrent abnormalities of chromosome bands 10q23-25 in non-Hodgkin's lymphoma. Genes Chromosomes Cancer 5:239.
-
(1992)
Genes Chromosomes Cancer
, vol.5
, pp. 239
-
-
Speaks, S.L.1
Sanger, W.G.2
Masih, A.S.3
Harrington, D.S.4
Hess, M.5
Armitage, J.O.6
-
5
-
-
0028851928
-
Allelotype analysis of childhood acute lymphoblastic leukemia
-
Takeuchi, S., C. R. Bartram, M. Wada, A. Reiter, Y. Hatta, T. Seriu, E. Lee, C. W. Miller, I. Miyoshi, and H. P. Koeffler. 1995. Allelotype analysis of childhood acute lymphoblastic leukemia. Cancer Res. 55:5377.
-
(1995)
Cancer Res.
, vol.55
, pp. 5377
-
-
Takeuchi, S.1
Bartram, C.R.2
Wada, M.3
Reiter, A.4
Hatta, Y.5
Seriu, T.6
Lee, E.7
Miller, C.W.8
Miyoshi, I.9
Koeffler, H.P.10
-
6
-
-
14444269482
-
MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines
-
Teng, D. H., R. Hu, H. Lin, T. Davis, D. Iliev, C. Frye, B. Swedlund, K. L. Hansen, V. L. Vinson, K. L. Gumpper, et al. 1997. MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines. Cancer Res. 57:5221.
-
(1997)
Cancer Res.
, vol.57
, pp. 5221
-
-
Teng, D.H.1
Hu, R.2
Lin, H.3
Davis, T.4
Iliev, D.5
Frye, C.6
Swedlund, B.7
Hansen, K.L.8
Vinson, V.L.9
Gumpper, K.L.10
-
7
-
-
0345147955
-
Alterations of the MMAC1/PTEN gene in lymphoid malignancies
-
Gronbaek, K., J. Zeuthen, P. Guldberg, E. Ralfkiaer, and K. Hou-Jensen. 1998. Alterations of the MMAC1/PTEN gene in lymphoid malignancies. Blood 91: 4388.
-
(1998)
Blood
, vol.91
, pp. 4388
-
-
Gronbaek, K.1
Zeuthen, J.2
Guldberg, P.3
Ralfkiaer, E.4
Hou-Jensen, K.5
-
8
-
-
0028228722
-
Cowden syndrome and lhermitte-Duclos disease in a family: A single genetic syndrome with pleiotropy?
-
Eng, C., V. Murday, S. Seal, S. Mohammed, S. V. Hodgson, M. A. Chaudary, I. S. Fentiman, B. A. J. Ponder, and R. A. Eeles. 1994. Cowden syndrome and Lhermitte-Duclos disease in a family: a single genetic syndrome with pleiotropy? J. Med. Genet. 31:458.
-
(1994)
J. Med. Genet.
, vol.31
, pp. 458
-
-
Eng, C.1
Murday, V.2
Seal, S.3
Mohammed, S.4
Hodgson, S.V.5
Chaudary, M.A.6
Fentiman, I.S.7
Ponder, B.A.J.8
Eeles, R.A.9
-
9
-
-
0031203265
-
Germline mutations in PTEN are present in Bannayan-Zonana syndrome
-
Marsh, D. J., P. L. M. Dahia, Z. Zheng, D. Liaw, R. Parsons, R. J. Gorlin, and C. Eng. 1997. Germline mutations in PTEN are present in Bannayan-Zonana syndrome. Nat. Genet. 16:333.
-
(1997)
Nat. Genet.
, vol.16
, pp. 333
-
-
Marsh, D.J.1
Dahia, P.L.M.2
Zheng, Z.3
Liaw, D.4
Parsons, R.5
Gorlin, R.J.6
Eng, C.7
-
10
-
-
0032475861
-
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
-
Stambolic, V., A. Suzuki, J. L. de la Pompa, G. M. Brothers, C. Mirtsos, T. Sasaki, J. Rulans, J. M. Penninger, D. P. Siderovski, and T. K. Mak. 1998. Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell 95:29.
-
(1998)
Cell
, vol.95
, pp. 29
-
-
Stambolic, V.1
Suzuki, A.2
De La Pompa, J.L.3
Brothers, G.M.4
Mirtsos, C.5
Sasaki, T.6
Rulans, J.7
Penninger, J.M.8
Siderovski, D.P.9
Mak, T.K.10
-
11
-
-
0030837555
-
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase
-
Myers, M. P., J. Stolarov, C. Eng, J. Li, S. I. Wang, M. H. Wigler, R. Parsons, and N. K. Tonks. 1997. P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Proc. Natl. Acad. Sci. USA 94:9052.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9052
-
-
Myers, M.P.1
Stolarov, J.2
Eng, C.3
Li, J.4
Wang, S.I.5
Wigler, M.H.6
Parsons, R.7
Tonks, N.K.8
-
12
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylionsitol 3,4,5-trisphosphate
-
Maehama, T., and J. E. Dixon. 1998. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylionsitol 3,4,5-trisphosphate. J. Biol. Chem. 273:13375.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 13375
-
-
Maehama, T.1
Dixon, J.E.2
-
13
-
-
0032506011
-
The lipid phosphatase activity of PTEN is critical for its tumor suppressor function
-
Myers, M. P., I. Pass, I. H. Batty, J. Van der Kaay, J. P. Stolarov, B. A. Hemmings, M. H. Wigler, C. P. Downes, and N. K. Tonks. 1998. The lipid phosphatase activity of PTEN is critical for its tumor suppressor function. Prof. Natl. Acad. Sci. USA 95:13513.
-
(1998)
Prof. Natl. Acad. Sci. USA
, vol.95
, pp. 13513
-
-
Myers, M.P.1
Pass, I.2
Batty, I.H.3
Van Der Kaay, J.4
Stolarov, J.P.5
Hemmings, B.A.6
Wigler, M.H.7
Downes, C.P.8
Tonks, N.K.9
-
14
-
-
0025917376
-
Novel polyphosphoinositides in cell growth and activation
-
Auger, K. R., and L. C. Cantley. 1991. Novel polyphosphoinositides in cell growth and activation. Cancer Cells 3:263.
-
(1991)
Cancer Cells
, vol.3
, pp. 263
-
-
Auger, K.R.1
Cantley, L.C.2
-
15
-
-
0031004088
-
Germline mutations of the PTEN gene in cowden disease, an inherited breast and thyroid cancer syndrome
-
Liaw, D., D. J. Marsh, J. Li, P. L. M. Dahia, S. I. Wang, Z. Zheng, S. Bose, K. M. Call, H. C. Tsou, M. Peacocket, et al. 1997. Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat. Genet. 16:64.
-
(1997)
Nat. Genet.
, vol.16
, pp. 64
-
-
Liaw, D.1
Marsh, D.J.2
Li, J.3
Dahia, P.L.M.4
Wang, S.I.5
Zheng, Z.6
Bose, S.7
Call, K.M.8
Tsou, H.C.9
Peacocket, M.10
-
16
-
-
0030801275
-
Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in primary breast carcinomas
-
Rhei, E., L. Kang, F. Bogomolniy, M. G. Federici, P. I. Borgen, and J. Boyd. 1997. Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in primary breast carcinomas. Cancer Res. 57:3657.
-
(1997)
Cancer Res.
, vol.57
, pp. 3657
-
-
Rhei, E.1
Kang, L.2
Bogomolniy, F.3
Federici, M.G.4
Borgen, P.I.5
Boyd, J.6
-
17
-
-
0030761409
-
Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies
-
Tashiro, H., M. S. Blazes, R. Wu, K. R. Cho, S. Bose, S. I. Wang, J. Li, R. Parsons, and H. Ellenson. 1997. Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies. Cancer Res. 57:3935.
-
(1997)
Cancer Res.
, vol.57
, pp. 3935
-
-
Tashiro, H.1
Blazes, M.S.2
Wu, R.3
Cho, K.R.4
Bose, S.5
Wang, S.I.6
Li, J.7
Parsons, R.8
Ellenson, H.9
-
18
-
-
0030728479
-
Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain
-
Furnari, F. B., H. Lin, H. S. Huang, and W. K. Cavenee. 1997. Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain. Proc. Natl. Acad. Sci. USA 94:12479.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 12479
-
-
Furnari, F.B.1
Lin, H.2
Huang, H.S.3
Cavenee, W.K.4
-
19
-
-
0032568273
-
Cancer predisposition: Where's the phosphate?
-
Smith, A., and A. Ashworth. 1998. Cancer predisposition: where's the phosphate? Curr. Biol. 8:241.
-
(1998)
Curr. Biol.
, vol.8
, pp. 241
-
-
Smith, A.1
Ashworth, A.2
-
20
-
-
0030024007
-
Inhibition of phosphatidylinositol 3-kinase blocks TCR/CD3-induced activation of the mitogen-activated kinase Erk2
-
von Willebrand, M., T. Jascur, N. Bonnefoy Berard, H. Yano, A. Altman, Y. Matsuda, and T. Mustelin. 1996. Inhibition of phosphatidylinositol 3-kinase blocks TCR/CD3-induced activation of the mitogen-activated kinase Erk2. Eur. J. Biochem. 235:828.
-
(1996)
Eur. J. Biochem.
, vol.235
, pp. 828
-
-
Von Willebrand, M.1
Jascur, T.2
Berard, N.B.3
Yano, H.4
Altman, A.5
Matsuda, Y.6
Mustelin, T.7
-
21
-
-
0029746173
-
Regulation of the lck SH2 domain by tyrosine phosphorylation
-
Couture, C., Z. Songyang, T. Jascur, S. Williams, P. Tailor, L. C. Cantley, and T. Mustelin. 1996. Regulation of the Lck SH2 domain by tyrosine phosphorylation. J. Biol. Chem. 271:24880.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 24880
-
-
Couture, C.1
Songyang, Z.2
Jascur, T.3
Williams, S.4
Tailor, P.5
Cantley, L.C.6
Mustelin, T.7
-
23
-
-
0029838105
-
Identification of the site in the Syk protein tyrosine kinase that binds the SH2 domain of lck
-
Couture, C., M. Deckert, S. Williams, F. Otero Russo, A. Altman, and T. Mustelin. 1996. Identification of the site in the Syk protein tyrosine kinase that binds the SH2 domain of Lck. J. Biol. Chem. 271:24294.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 24294
-
-
Couture, C.1
Deckert, M.2
Williams, S.3
Russo, F.O.4
Altman, A.5
Mustelin, T.6
-
24
-
-
0030970079
-
Reconstitution of TCR-induced Erk2 kinase activation in Lck-negative JCaM1 cells by Syk, but not Zap
-
Williams, S., C. Couture, J. Gilman, T. Jascur, M. Deckert, A. Altman, and T. Mustelin. 1997. Reconstitution of TCR-induced Erk2 kinase activation in Lck-negative JCaM1 cells by Syk, but not Zap. Eur. J. Biochem. 245:84.
-
(1997)
Eur. J. Biochem.
, vol.245
, pp. 84
-
-
Williams, S.1
Couture, C.2
Gilman, J.3
Jascur, T.4
Deckert, M.5
Altman, A.6
Mustelin, T.7
-
25
-
-
0029160069
-
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
-
Burgering, B. M., and P. J. Coffer. 1995. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376:599.
-
(1995)
Nature
, vol.376
, pp. 599
-
-
Burgering, B.M.1
Coffer, P.J.2
-
26
-
-
0029079275
-
The protein kinase encoded by the Akt proto-oncogene is a target of PDGF-activated phosphatidylinositol 3-kinase
-
Franke, T. F., S. I. Yang, T. O. Chan, K. Datta, A. Kazlauskas, D. K. Morrison, D. R. Kaplan, and, P. N. Tsichlis. 1995. The protein kinase encoded by the Akt proto-oncogene is a target of PDGF-activated phosphatidylinositol 3-kinase. Cell 81:727.
-
(1995)
Cell
, vol.81
, pp. 727
-
-
Franke, T.F.1
Yang, S.I.2
Chan, T.O.3
Datta, K.4
Kazlauskas, A.5
Morrison, D.K.6
Kaplan, D.R.7
Tsichlis, P.N.8
-
27
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
-
Datta, S. R., H. Dudek, X. Tao, S. Masters, H. Fu, Y. Gotoh, and M. E. Greenberg. 1997. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91:231.
-
(1997)
Cell
, vol.91
, pp. 231
-
-
Datta, S.R.1
Dudek, H.2
Tao, X.3
Masters, S.4
Fu, H.5
Gotoh, Y.6
Greenberg, M.E.7
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