-
1
-
-
4143125425
-
Genomic analysis of Drosophila melanogaster telomeres: Full-length copies of HeT-A and TART elements at telomeres
-
Abad JP, De Pablos B, Osoegawa K, De Jong PJ, Martin-Gallardo A, Villasante A (2004) Genomic analysis of Drosophila melanogaster telomeres: full-length copies of HeT-A and TART elements at telomeres. Mol Biol Evol 21: 1613-1619
-
(2004)
Mol Biol Evol
, vol.21
, pp. 1613-1619
-
-
Abad, J.P.1
De Pablos, B.2
Osoegawa, K.3
De Jong, P.J.4
Martin-Gallardo, A.5
Villasante, A.6
-
2
-
-
37349107849
-
Interplay of chromatin modifiers on a short basic patch of histone H4 tail defines the boundary of telomeric heterochromatin
-
Altaf M, Utley RT, Lacoste N, Tan S, Briggs SD, Cote J (2007) Interplay of chromatin modifiers on a short basic patch of histone H4 tail defines the boundary of telomeric heterochromatin. Mol Cell 28: 1002-1014
-
(2007)
Mol Cell
, vol.28
, pp. 1002-1014
-
-
Altaf, M.1
Utley, R.T.2
Lacoste, N.3
Tan, S.4
Briggs, S.D.5
Cote, J.6
-
3
-
-
0028873187
-
Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation
-
Allshire RC, Nimmo ER, Ekwall K, Javerzat JP, Cranston G (1995) Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation. Genes Dev 9: 218-233
-
(1995)
Genes Dev
, vol.9
, pp. 218-233
-
-
Allshire, R.C.1
Nimmo, E.R.2
Ekwall, K.3
Javerzat, J.P.4
Cranston, G.5
-
4
-
-
0037480961
-
Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation
-
Allsopp RC, Morin GB, DePinho R, Harley CB, Weissman IL (2003) Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation. Blood 102: 517-520
-
(2003)
Blood
, vol.102
, pp. 517-520
-
-
Allsopp, R.C.1
Morin, G.B.2
DePinho, R.3
Harley, C.B.4
Weissman, I.L.5
-
5
-
-
40849138186
-
Molecular population genetics of Drosophila subtelomeric DNA
-
Anderson JA, Song YS, Langley CH (2008) Molecular population genetics of Drosophila subtelomeric DNA. Genetics 178: 477-487
-
(2008)
Genetics
, vol.178
, pp. 477-487
-
-
Anderson, J.A.1
Song, Y.S.2
Langley, C.H.3
-
6
-
-
30544432864
-
Three distinct chromatin domains in telomere ends of polytene chromosomes in Drosophila melanogaster Tel mutants
-
Andreyeva EN, Belyaeva ES, Semeshin VF, Pokholkova GV, Zhimulev IF (2005) Three distinct chromatin domains in telomere ends of polytene chromosomes in Drosophila melanogaster Tel mutants. J Cell Sci 118: 5465-5477
-
(2005)
J Cell Sci
, vol.118
, pp. 5465-5477
-
-
Andreyeva, E.N.1
Belyaeva, E.S.2
Semeshin, V.F.3
Pokholkova, G.V.4
Zhimulev, I.F.5
-
7
-
-
0025900189
-
Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae
-
Aparicio OM, Billington BL, Gottschling DE (1991) Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae. Cell 66: 1279-1287
-
(1991)
Cell
, vol.66
, pp. 1279-1287
-
-
Aparicio, O.M.1
Billington, B.L.2
Gottschling, D.E.3
-
8
-
-
34248160438
-
Developmentally regulated piRNA clusters implicate MILI in transposon control
-
Aravin AA, Sachidanandam R, Girard A, Fejes-Toth K, Hannon GJ (2007) Developmentally regulated piRNA clusters implicate MILI in transposon control. Science 316: 744-747
-
(2007)
Science
, vol.316
, pp. 744-747
-
-
Aravin, A.A.1
Sachidanandam, R.2
Girard, A.3
Fejes-Toth, K.4
Hannon, G.J.5
-
9
-
-
0037062454
-
Constitutive telomerase expression promotes mammary carcinomas in aging mice
-
Artandi SE, Alson S, Tietze MK, Sharpless NE, Ye S, Greenberg RA, Castrillon DH, Homer JW, Weiler SR, Carrasco RD, DePinho RA (2002) Constitutive telomerase expression promotes mammary carcinomas in aging mice. Proc Natl Acad Sci USA 99: 8191-8196
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 8191-8196
-
-
Artandi, S.E.1
Alson, S.2
Tietze, M.K.3
Sharpless, N.E.4
Ye, S.5
Greenberg, R.A.6
Castrillon, D.H.7
Homer, J.W.8
Weiler, S.R.9
Carrasco, R.D.10
DePinho, R.A.11
-
10
-
-
37349043972
-
Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends
-
Azzalin CM, Reichenbach P, Khoriauli L, Giulotto E, Lingner J (2007) Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends. Science 318: 798-801
-
(2007)
Science
, vol.318
, pp. 798-801
-
-
Azzalin, C.M.1
Reichenbach, P.2
Khoriauli, L.3
Giulotto, E.4
Lingner, J.5
-
11
-
-
0035282458
-
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
-
Bannister AJ, Zegerman P, Partridge JF, Miska EA, Thomas JO, Allshire RC, Kouzarides T (2001) Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature 410: 120-124
-
(2001)
Nature
, vol.410
, pp. 120-124
-
-
Bannister, A.J.1
Zegerman, P.2
Partridge, J.F.3
Miska, E.A.4
Thomas, J.O.5
Allshire, R.C.6
Kouzarides, T.7
-
13
-
-
0032126345
-
Cytosine methylation of repeated sequences in eukaryotes: The role of DNA pairing
-
Bender J (1998) Cytosine methylation of repeated sequences in eukaryotes: the role of DNA pairing. Trends Biochem Sci 23: 252-256
-
(1998)
Trends Biochem Sci
, vol.23
, pp. 252-256
-
-
Bender, J.1
-
14
-
-
33846590977
-
Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres
-
Benetti R, Garcia-Cao M, Blasco MA (2007a) Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres. Nat Genet 39: 243-250
-
(2007)
Nat Genet
, vol.39
, pp. 243-250
-
-
Benetti, R.1
Garcia-Cao, M.2
Blasco, M.A.3
-
15
-
-
40949100837
-
A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases
-
Benetti R, Gonzalo S, Jaco I, Munoz P, Gonzalez S, Schoeftner S, Murchison E, Andl T, Chen T, Klatt P, Li E, Serrano M, Millar S, Hannon G, Blasco MA (2008a) A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases. Nat Struct Mol Biol 15: 268-279
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 268-279
-
-
Benetti, R.1
Gonzalo, S.2
Jaco, I.3
Munoz, P.4
Gonzalez, S.5
Schoeftner, S.6
Murchison, E.7
Andl, T.8
Chen, T.9
Klatt, P.10
Li, E.11
Serrano, M.12
Millar, S.13
Hannon, G.14
Blasco, M.A.15
-
16
-
-
34548827379
-
Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination
-
Benetti R, Gonzalo S, Jaco I, Schotta G, Klatt P, Jenuwein T, Blasco MA (2007b) Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination. J Cell Biol 178: 925-936
-
(2007)
J Cell Biol
, vol.178
, pp. 925-936
-
-
Benetti, R.1
Gonzalo, S.2
Jaco, I.3
Schotta, G.4
Klatt, P.5
Jenuwein, T.6
Blasco, M.A.7
-
18
-
-
23044437498
-
RNA meets chromatin
-
Bernstein E, Allis CD (2005) RNA meets chromatin. Genes Dev 19: 1635-1655
-
(2005)
Genes Dev
, vol.19
, pp. 1635-1655
-
-
Bernstein, E.1
Allis, C.D.2
-
19
-
-
33644558048
-
Subtelomeric proteins negatively regulate telomere elongation in budding yeast
-
Berthiau AS, Yankulov K, Bah A, Revardel E, Luciano P, Wellinger RJ, Geli V, Gilson E (2006) Subtelomeric proteins negatively regulate telomere elongation in budding yeast. EMBO J 25: 846-856
-
(2006)
EMBO J
, vol.25
, pp. 846-856
-
-
Berthiau, A.S.1
Yankulov, K.2
Bah, A.3
Revardel, E.4
Luciano, P.5
Wellinger, R.J.6
Geli, V.7
Gilson, E.8
-
20
-
-
27244436111
-
Drosophila ATM and ATR checkpoint kinases control partially redundant pathways for telomere maintenance
-
Bi X, Srikanta D, Fanti L, Pimpinelli S, Badugu R, Kellum R, Rong YS (2005) Drosophila ATM and ATR checkpoint kinases control partially redundant pathways for telomere maintenance. Proc Natl Acad Sci USA 102: 15167-15172
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 15167-15172
-
-
Bi, X.1
Srikanta, D.2
Fanti, L.3
Pimpinelli, S.4
Badugu, R.5
Kellum, R.6
Rong, Y.S.7
-
21
-
-
0027233733
-
The genomic organization of HeT-A retroposons in Drosophila melanogaster
-
Biessmann H, Kasravi B, Jakes K, Bui T, Ikenaga K, Mason JM (1993) The genomic organization of HeT-A retroposons in Drosophila melanogaster. Chromosoma 102: 297-305
-
(1993)
Chromosoma
, vol.102
, pp. 297-305
-
-
Biessmann, H.1
Kasravi, B.2
Jakes, K.3
Bui, T.4
Ikenaga, K.5
Mason, J.M.6
-
22
-
-
0345256398
-
Telomerase-independent mechanisms of telomere elongation
-
Biessmann H, Mason JM (2003) Telomerase-independent mechanisms of telomere elongation. Cell Mol Life Sci 60: 2325-2333
-
(2003)
Cell Mol Life Sci
, vol.60
, pp. 2325-2333
-
-
Biessmann, H.1
Mason, J.M.2
-
24
-
-
50849134865
-
Role of heterochromatin in suppressing subtelomeric recombination in fission yeast
-
Bisht KK, Arora S, Ahmed S, Singh J (2008) Role of heterochromatin in suppressing subtelomeric recombination in fission yeast. Yeast 25: 537-548
-
(2008)
Yeast
, vol.25
, pp. 537-548
-
-
Bisht, K.K.1
Arora, S.2
Ahmed, S.3
Singh, J.4
-
25
-
-
17144420804
-
Mice with bad ends: Mouse models for the study of telomeres and telomerase in cancer and aging
-
Blasco MA (2005) Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging. EMBO J 24: 1095-1103
-
(2005)
EMBO J
, vol.24
, pp. 1095-1103
-
-
Blasco, M.A.1
-
26
-
-
33947317206
-
The epigenetic regulation of mammalian telomeres
-
Blasco MA (2007) The epigenetic regulation of mammalian telomeres. Nat Rev Genet 8: 299-309
-
(2007)
Nat Rev Genet
, vol.8
, pp. 299-309
-
-
Blasco, M.A.1
-
27
-
-
0030931491
-
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
-
Blasco MA, Lee HW, Hande MP, Samper E, Lansdorp PM, DePinho RA, Greider CW (1997) Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 91: 25-34
-
(1997)
Cell
, vol.91
, pp. 25-34
-
-
Blasco, M.A.1
Lee, H.W.2
Hande, M.P.3
Samper, E.4
Lansdorp, P.M.5
DePinho, R.A.6
Greider, C.W.7
-
28
-
-
0010045614
-
Extension of life-span by introduction of telomerase into normal human cells
-
Bodnar AG, Ouellette M, Frolkis M, Holt SE, Chiu CP, Morin GB, Harley CB, Shay JW, Lichtsteiner S, Wright WE (1998) Extension of life-span by introduction of telomerase into normal human cells. Science 279: 349-352
-
(1998)
Science
, vol.279
, pp. 349-352
-
-
Bodnar, A.G.1
Ouellette, M.2
Frolkis, M.3
Holt, S.E.4
Chiu, C.P.5
Morin, G.B.6
Harley, C.B.7
Shay, J.W.8
Lichtsteiner, S.9
Wright, W.E.10
-
29
-
-
0038530976
-
Telomeric associated sequences of Drosophila recruit polycomb-group proteins in vivo and can induce pairing-sensitive repression
-
Boivin A, Gaily C, Netter S, Anxolabehere D, Ronsseray S (2003) Telomeric associated sequences of Drosophila recruit polycomb-group proteins in vivo and can induce pairing-sensitive repression. Genetics 164: 195-208
-
(2003)
Genetics
, vol.164
, pp. 195-208
-
-
Boivin, A.1
Gaily, C.2
Netter, S.3
Anxolabehere, D.4
Ronsseray, S.5
-
30
-
-
33947273235
-
Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila
-
Brennecke J, Aravin AA, Stark A, Dus M, Kellis M, Sachidanandam R, Hannon GJ (2007) Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell 128: 1089-1103
-
(2007)
Cell
, vol.128
, pp. 1089-1103
-
-
Brennecke, J.1
Aravin, A.A.2
Stark, A.3
Dus, M.4
Kellis, M.5
Sachidanandam, R.6
Hannon, G.J.7
-
31
-
-
0036682364
-
Gene silencing: Trans-histone regulatory pathway in chromatin
-
Briggs SD, Xiao T, Sun ZW, Caldwell JA, Shabanowitz J, Hunt DF, Allis CD, Strahl BD (2002) Gene silencing: trans-histone regulatory pathway in chromatin. Nature 418: 498
-
(2002)
Nature
, vol.418
, pp. 498
-
-
Briggs, S.D.1
Xiao, T.2
Sun, Z.W.3
Caldwell, J.A.4
Shabanowitz, J.5
Hunt, D.F.6
Allis, C.D.7
Strahl, B.D.8
-
32
-
-
34548822460
-
Drosophila PIWI associates with chromatin and interacts directly with HP1a
-
Brower-Toland B, Findley SD, Jiang L, Liu L, Yin H, Dus M, Zhou P, Elgin SC, Lin H (2007) Drosophila PIWI associates with chromatin and interacts directly with HP1a. Genes Dev 21: 2300-2311
-
(2007)
Genes Dev
, vol.21
, pp. 2300-2311
-
-
Brower-Toland, B.1
Findley, S.D.2
Jiang, L.3
Liu, L.4
Yin, H.5
Dus, M.6
Zhou, P.7
Elgin, S.C.8
Lin, H.9
-
33
-
-
2942538551
-
Constitutive expression of tert in thymocytes leads to increased incidence and dissemination of T-cell lymphoma in Lck-Tert mice
-
Canela A, Martin-Caballero J, Flores JM, Blasco MA (2004) Constitutive expression of tert in thymocytes leads to increased incidence and dissemination of T-cell lymphoma in Lck-Tert mice. Mol Cell Biol 24: 4275-4293
-
(2004)
Mol Cell Biol
, vol.24
, pp. 4275-4293
-
-
Canela, A.1
Martin-Caballero, J.2
Flores, J.M.3
Blasco, M.A.4
-
34
-
-
33947720638
-
MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline
-
Carmell MA, Girard A, van de Kant HJ, Bourc'his D, Bestor TH, de Rooij DG, Hannon GJ (2007) MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline. Dev Cell 12: 503-514
-
(2007)
Dev Cell
, vol.12
, pp. 503-514
-
-
Carmell, M.A.1
Girard, A.2
van de Kant, H.J.3
Bourc'his, D.4
Bestor, T.H.5
de Rooij, D.G.6
Hannon, G.J.7
-
35
-
-
0037085264
-
Acetylation of the yeast histone H4 N terminus regulates its binding to heterochromatin protein SIR3
-
Carmen AA, Milne L, Grunstein M (2002) Acetylation of the yeast histone H4 N terminus regulates its binding to heterochromatin protein SIR3. J Biol Chem 277: 4778-4781
-
(2002)
J Biol Chem
, vol.277
, pp. 4778-4781
-
-
Carmen, A.A.1
Milne, L.2
Grunstein, M.3
-
36
-
-
0037308404
-
Association between telomere length in blood and mortality in people aged 60 years or older
-
Cawthon RM, Smith KR, O'Brien E, Sivatchenko A, Kerber RA (2003) Association between telomere length in blood and mortality in people aged 60 years or older. Lancet 361: 393-395
-
(2003)
Lancet
, vol.361
, pp. 393-395
-
-
Cawthon, R.M.1
Smith, K.R.2
O'Brien, E.3
Sivatchenko, A.4
Kerber, R.A.5
-
37
-
-
25144468434
-
The mechanism of telomere protection: A comparison between Drosophila and humans
-
Cenci G, Ciapponi L, Gatti M (2005) The mechanism of telomere protection: a comparison between Drosophila and humans. Chromosoma 114: 135-145
-
(2005)
Chromosoma
, vol.114
, pp. 135-145
-
-
Cenci, G.1
Ciapponi, L.2
Gatti, M.3
-
38
-
-
33746429164
-
The Drosophila Nbs protein functions in multiple pathways for the maintenance of genome stability
-
Ciapponi L, Cenci G, Gatti M (2006) The Drosophila Nbs protein functions in multiple pathways for the maintenance of genome stability. Genetics 173: 1447-1454
-
(2006)
Genetics
, vol.173
, pp. 1447-1454
-
-
Ciapponi, L.1
Cenci, G.2
Gatti, M.3
-
39
-
-
0036884829
-
The retinoblastoma tumour suppressor in development and cancer
-
Classon M, Harlow E (2002) The retinoblastoma tumour suppressor in development and cancer. Nat Rev Cancer 2: 910-917
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 910-917
-
-
Classon, M.1
Harlow, E.2
-
40
-
-
0037148271
-
Telomerase in the human organism
-
Collins K, Mitchell JR (2002) Telomerase in the human organism. Oncogene 21: 564-579
-
(2002)
Oncogene
, vol.21
, pp. 564-579
-
-
Collins, K.1
Mitchell, J.R.2
-
41
-
-
0031038170
-
Regulation of telomere length and function by a Myb-domain protein in fission yeast
-
Cooper JP, Nimmo ER, Allshire RC, Cech TR (1997) Regulation of telomere length and function by a Myb-domain protein in fission yeast. Nature 385: 744-747
-
(1997)
Nature
, vol.385
, pp. 744-747
-
-
Cooper, J.P.1
Nimmo, E.R.2
Allshire, R.C.3
Cech, T.R.4
-
43
-
-
0037224923
-
Telomere-based crisis: Functional differences between telomerase activation and ALT in tumor progression
-
Chang S, Khoo CM, Naylor ML, Maser RS, DePinho RA (2003) Telomere-based crisis: functional differences between telomerase activation and ALT in tumor progression. Genes Dev 17: 88-100
-
(2003)
Genes Dev
, vol.17
, pp. 88-100
-
-
Chang, S.1
Khoo, C.M.2
Naylor, M.L.3
Maser, R.S.4
DePinho, R.A.5
-
44
-
-
29644440388
-
Establishment and maintenance of DNA methylation patterns in mammals
-
Chen T, Li E (2006) Establishment and maintenance of DNA methylation patterns in mammals. Curr Top Microbiol Immunol 301: 179-201
-
(2006)
Curr Top Microbiol Immunol
, vol.301
, pp. 179-201
-
-
Chen, T.1
Li, E.2
-
45
-
-
0035899866
-
Telomere binding of the Rap1 protein is required for meiosis in fission yeast
-
Chikashige Y, Hiraoka Y (2001) Telomere binding of the Rap1 protein is required for meiosis in fission yeast. Curr Biol 11: 1618-1623
-
(2001)
Curr Biol
, vol.11
, pp. 1618-1623
-
-
Chikashige, Y.1
Hiraoka, Y.2
-
46
-
-
0344441890
-
A DNA damage checkpoint response in telomere-initiated senescence
-
d'Adda di Fagagna F, Reaper PM, Clay-Farrace L, Fiegler H, Carr P, Von Zglinicki T, Saretzki G, Carter NP, Jackson SP (2003) A DNA damage checkpoint response in telomere-initiated senescence. Nature 426: 194-198
-
(2003)
Nature
, vol.426
, pp. 194-198
-
-
d'Adda di Fagagna, F.1
Reaper, P.M.2
Clay-Farrace, L.3
Fiegler, H.4
Carr, P.5
Von Zglinicki, T.6
Saretzki, G.7
Carter, N.P.8
Jackson, S.P.9
-
47
-
-
67149099680
-
Histone H4 lysine 16 acetylation regulates cellular lifespan
-
Dang W, Steffen KK, Perry R, Dorsey JA, Johnson FB, Shilatifard A, Kaeberlein M, Kennedy BK, Berger SL (2009) Histone H4 lysine 16 acetylation regulates cellular lifespan. Nature 459: 802-807
-
(2009)
Nature
, vol.459
, pp. 802-807
-
-
Dang, W.1
Steffen, K.K.2
Perry, R.3
Dorsey, J.A.4
Johnson, F.B.5
Shilatifard, A.6
Kaeberlein, M.7
Kennedy, B.K.8
Berger, S.L.9
-
48
-
-
0033781559
-
Telomere folding is required for the stable maintenance of telomere position effects in yeast
-
de Bruin D, Kantrow SM, Liberatore RA, Zakian VA (2000) Telomere folding is required for the stable maintenance of telomere position effects in yeast. Mol Cell Biol 20: 7991-8000
-
(2000)
Mol Cell Biol
, vol.20
, pp. 7991-8000
-
-
de Bruin, D.1
Kantrow, S.M.2
Liberatore, R.A.3
Zakian, V.A.4
-
49
-
-
33747798962
-
Non-coding RNA in fly dosage compensation
-
Deng X, Meller VH (2006) Non-coding RNA in fly dosage compensation. Trends Biochem Sci 31: 526-532
-
(2006)
Trends Biochem Sci
, vol.31
, pp. 526-532
-
-
Deng, X.1
Meller, V.H.2
-
50
-
-
57549088840
-
Telomeric position effect - a third silencing mechanism in eukaryotes
-
Doheny JG, Mottus R, Grigliatti TA (2008) Telomeric position effect - a third silencing mechanism in eukaryotes. PLoS One 3: e3864
-
(2008)
PLoS One
, vol.3
-
-
Doheny, J.G.1
Mottus, R.2
Grigliatti, T.A.3
-
51
-
-
12144290585
-
Enhanced gene targeting frequency in ES cells with low genomic methylation levels
-
Dominguez-Bendala J, McWhir J (2004) Enhanced gene targeting frequency in ES cells with low genomic methylation levels. Transgenic Res 13: 69-74
-
(2004)
Transgenic Res
, vol.13
, pp. 69-74
-
-
Dominguez-Bendala, J.1
McWhir, J.2
-
52
-
-
0037047323
-
Methylation of histone H3 by COMPASS requires ubiquitination of histone H2B by Rad6
-
Dover J, Schneider J, Tawiah-Boateng MA, Wood A, Dean K, Johnston M, Shilatifard A (2002) Methylation of histone H3 by COMPASS requires ubiquitination of histone H2B by Rad6. J Biol Chem 277: 28368-28371
-
(2002)
J Biol Chem
, vol.277
, pp. 28368-28371
-
-
Dover, J.1
Schneider, J.2
Tawiah-Boateng, M.A.3
Wood, A.4
Dean, K.5
Johnston, M.6
Shilatifard, A.7
-
53
-
-
0029120080
-
The chromodomain protein Swi6: A key component at fission yeast centromeres
-
Ekwall K, Javerzat JP, Lorentz A, Schmidt H, Cranston G, Allshire R (1995) The chromodomain protein Swi6: a key component at fission yeast centromeres. Science 269: 1429-1431
-
(1995)
Science
, vol.269
, pp. 1429-1431
-
-
Ekwall, K.1
Javerzat, J.P.2
Lorentz, A.3
Schmidt, H.4
Cranston, G.5
Allshire, R.6
-
54
-
-
0029859275
-
Mutations in the fission yeast silencing factors clr4 + and rik1 + disrupt the localisation of the chromo domain protein Swi6p and impair centromere function
-
Ekwall K, Nimmo ER, Javerzat JP, Borgstrom B, Egel R, Cranston G, Allshire R (1996) Mutations in the fission yeast silencing factors clr4 + and rik1 + disrupt the localisation of the chromo domain protein Swi6p and impair centromere function. J Cell Sci 109(Part 11): 2637-2648
-
(1996)
J Cell Sci
, vol.109
, Issue.PART 11
, pp. 2637-2648
-
-
Ekwall, K.1
Nimmo, E.R.2
Javerzat, J.P.3
Borgstrom, B.4
Egel, R.5
Cranston, G.6
Allshire, R.7
-
55
-
-
10344229954
-
Accelerated telomere shortening in response to life stress
-
Epel ES, Blackburn EH, Lin J, Dhabhar FS, Adler NE, Morrow JD, Cawthon RM (2004) Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci USA 101: 17312-17315
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 17312-17315
-
-
Epel, E.S.1
Blackburn, E.H.2
Lin, J.3
Dhabhar, F.S.4
Adler, N.E.5
Morrow, J.D.6
Cawthon, R.M.7
-
56
-
-
0032215539
-
The heterochromatin protein 1 prevents telomere fusions in Drosophila
-
Fanti L, Giovinazzo G, Berloco M, Pimpinelli S (1998) The heterochromatin protein 1 prevents telomere fusions in Drosophila. Mol Cell 2: 527-538
-
(1998)
Mol Cell
, vol.2
, pp. 527-538
-
-
Fanti, L.1
Giovinazzo, G.2
Berloco, M.3
Pimpinelli, S.4
-
57
-
-
34547949573
-
A charge-based interaction between histone H4 and Dot1 is required for H3K79 methylation and telomere silencing: Identification of a new trans-histone pathway
-
Fingerman IM, Li HC, Briggs SD (2007) A charge-based interaction between histone H4 and Dot1 is required for H3K79 methylation and telomere silencing: identification of a new trans-histone pathway. Genes Dev 21: 2018-2029
-
(2007)
Genes Dev
, vol.21
, pp. 2018-2029
-
-
Fingerman, I.M.1
Li, H.C.2
Briggs, S.D.3
-
58
-
-
40349085766
-
The longest telomeres: A general signature of adult stem cell compartments
-
Flores I, Canela A, Vera E, Tejera A, Cotsarelis G, Blasco MA (2008) The longest telomeres: a general signature of adult stem cell compartments. Genes Dev 22: 654-667
-
(2008)
Genes Dev
, vol.22
, pp. 654-667
-
-
Flores, I.1
Canela, A.2
Vera, E.3
Tejera, A.4
Cotsarelis, G.5
Blasco, M.A.6
-
59
-
-
23844540299
-
Effects of telomerase and telomere length on epidermal stem cell behavior
-
Flores I, Cayuela ML, Blasco MA (2005) Effects of telomerase and telomere length on epidermal stem cell behavior. Science 309: 1253-1256
-
(2005)
Science
, vol.309
, pp. 1253-1256
-
-
Flores, I.1
Cayuela, M.L.2
Blasco, M.A.3
-
60
-
-
20144388146
-
Loss of acetylation at Lysl6 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
-
Fraga MF, Ballestar E, Villar-Garea A, Boix-Chornet M, Espada J, Schotta G, Bonaldi T, Haydon C, Ropero S, Petrie K, Iyer NG, Perez-Rosado A, Calvo E, Lopez JA, Cano A, Calasanz MJ, Colomer D, Piris MA, Ahn N, Imhof A et al (2005) Loss of acetylation at Lysl6 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat Genet 37: 391-400
-
(2005)
Nat Genet
, vol.37
, pp. 391-400
-
-
Fraga, M.F.1
Ballestar, E.2
Villar-Garea, A.3
Boix-Chornet, M.4
Espada, J.5
Schotta, G.6
Bonaldi, T.7
Haydon, C.8
Ropero, S.9
Petrie, K.10
Iyer, N.G.11
Perez-Rosado, A.12
Calvo, E.13
Lopez, J.A.14
Cano, A.15
Calasanz, M.J.16
Colomer, D.17
Piris, M.A.18
Ahn, N.19
Imhof, A.20
more..
-
61
-
-
56049115829
-
HP1 is distributed within distinct chromatin domains at Drosophila telomeres
-
Frydrychova RC, Mason JM, Archer TK (2008) HP1 is distributed within distinct chromatin domains at Drosophila telomeres. Genetics 180: 121-131
-
(2008)
Genetics
, vol.180
, pp. 121-131
-
-
Frydrychova, R.C.1
Mason, J.M.2
Archer, T.K.3
-
62
-
-
0038412822
-
The DNA methyl-transferases associate with HP1 and the SUV39H1 histone methyltransferase
-
Fuks F, Hurd PJ, Deplus R, Kouzarides T (2003) The DNA methyl-transferases associate with HP1 and the SUV39H1 histone methyltransferase. Nucleic Acids Res 31: 2305-2312
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 2305-2312
-
-
Fuks, F.1
Hurd, P.J.2
Deplus, R.3
Kouzarides, T.4
-
63
-
-
33745223517
-
Increased p53 activity does not accelerate telomere-driven ageing
-
Garcia-Cao I, Garcia-Cao M, Tomas-Loba A, Martin-Caballero J, Flores JM, Klatt P, Blasco MA, Serrano M (2006) Increased p53 activity does not accelerate telomere-driven ageing. EMBO Rep 7: 546-552
-
(2006)
EMBO Rep
, vol.7
, pp. 546-552
-
-
Garcia-Cao, I.1
Garcia-Cao, M.2
Tomas-Loba, A.3
Martin-Caballero, J.4
Flores, J.M.5
Klatt, P.6
Blasco, M.A.7
Serrano, M.8
-
64
-
-
0347988045
-
Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases
-
Garcia-Cao M, O'Sullivan R, Peters AH, Jenuwein T, Blasco MA (2004) Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases. Nat Genet 36: 94-99
-
(2004)
Nat Genet
, vol.36
, pp. 94-99
-
-
Garcia-Cao, M.1
O'Sullivan, R.2
Peters, A.H.3
Jenuwein, T.4
Blasco, M.A.5
-
65
-
-
11144296359
-
Sir-mediated repression can occur independently of chromosomal and subnuclear contexts
-
Gartenberg MR, Neumann FR, Laroche T, Blaszczyk M, Gasser SM (2004) Sir-mediated repression can occur independently of chromosomal and subnuclear contexts. Cell 119: 955-967
-
(2004)
Cell
, vol.119
, pp. 955-967
-
-
Gartenberg, M.R.1
Neumann, F.R.2
Laroche, T.3
Blaszczyk, M.4
Gasser, S.M.5
-
66
-
-
0343228751
-
Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis
-
Gonzalez-Suarez E, Samper E, Flores JM, Blasco MA (2000) Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis. Nat Genet 26: 114-117
-
(2000)
Nat Genet
, vol.26
, pp. 114-117
-
-
Gonzalez-Suarez, E.1
Samper, E.2
Flores, J.M.3
Blasco, M.A.4
-
67
-
-
0035355340
-
Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes
-
Gonzalez-Suarez E, Samper E, Ramirez A, Flores JM, Martin-Caballero J, Jorcano JL, Blasco MA (2001) Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes. EMBO J 20: 2619-2630
-
(2001)
EMBO J
, vol.20
, pp. 2619-2630
-
-
Gonzalez-Suarez, E.1
Samper, E.2
Ramirez, A.3
Flores, J.M.4
Martin-Caballero, J.5
Jorcano, J.L.6
Blasco, M.A.7
-
68
-
-
25144491542
-
Role of Rb family in the epigenetic definition of chromatin
-
Gonzalo S, Blasco MA (2005) Role of Rb family in the epigenetic definition of chromatin. Cell Cycle 4: 752-755
-
(2005)
Cell Cycle
, vol.4
, pp. 752-755
-
-
Gonzalo, S.1
Blasco, M.A.2
-
69
-
-
20244376464
-
Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin
-
Gonzalo S, Garcia-Cao M, Fraga MF, Schotta G, Peters AH, Cotter SE, Eguia R, Dean DC, Esteller M, Jenuwein T, Blasco MA (2005) Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin. Nat Cell Biol 7: 420-428
-
(2005)
Nat Cell Biol
, vol.7
, pp. 420-428
-
-
Gonzalo, S.1
Garcia-Cao, M.2
Fraga, M.F.3
Schotta, G.4
Peters, A.H.5
Cotter, S.E.6
Eguia, R.7
Dean, D.C.8
Esteller, M.9
Jenuwein, T.10
Blasco, M.A.11
-
70
-
-
33645702660
-
DNA methyltransferases control telomere length and telomere recombination in mammalian cells
-
Gonzalo S, Jaco I, Fraga MF, Chen T, Li E, Esteller M, Blasco MA (2006) DNA methyltransferases control telomere length and telomere recombination in mammalian cells. Nat Cell Biol 8: 416-424
-
(2006)
Nat Cell Biol
, vol.8
, pp. 416-424
-
-
Gonzalo, S.1
Jaco, I.2
Fraga, M.F.3
Chen, T.4
Li, E.5
Esteller, M.6
Blasco, M.A.7
-
71
-
-
0025201982
-
Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription
-
Gottschling DE, Aparicio OM, Billington BL, Zakian VA (1990) Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription. Cell 63: 751-762
-
(1990)
Cell
, vol.63
, pp. 751-762
-
-
Gottschling, D.E.1
Aparicio, O.M.2
Billington, B.L.3
Zakian, V.A.4
-
72
-
-
0029088371
-
TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene
-
Greenwell PW, Kronmal SL, Porter SE, Gassenhuber J, Obermaier B, Petes TD (1995) TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene. Cell 82: 823-829
-
(1995)
Cell
, vol.82
, pp. 823-829
-
-
Greenwell, P.W.1
Kronmal, S.L.2
Porter, S.E.3
Gassenhuber, J.4
Obermaier, B.5
Petes, T.D.6
-
73
-
-
0033553536
-
Mammalian telomeres end in a large duplex loop
-
Griffith JD, Comeau L, Rosenfield S, Stansel RM, Bianchi A, Moss H, de Lange T (1999) Mammalian telomeres end in a large duplex loop. Cell 97: 503-514
-
(1999)
Cell
, vol.97
, pp. 503-514
-
-
Griffith, J.D.1
Comeau, L.2
Rosenfield, S.3
Stansel, R.M.4
Bianchi, A.5
Moss, H.6
de Lange, T.7
-
74
-
-
33947390781
-
A slicer-mediated mechanism for repeat-associated siRNA 5′ end formation in Drosophila
-
Gunawardane LS, Saito K, Nishida KM, Miyoshi K, Kawamura Y, Nagami T, Siomi H, Siomi MC (2007) A slicer-mediated mechanism for repeat-associated siRNA 5′ end formation in Drosophila. Science 315: 1587-1590
-
(2007)
Science
, vol.315
, pp. 1587-1590
-
-
Gunawardane, L.S.1
Saito, K.2
Nishida, K.M.3
Miyoshi, K.4
Kawamura, Y.5
Nagami, T.6
Siomi, H.7
Siomi, M.C.8
-
75
-
-
0033593814
-
Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice
-
Hande MP, Samper E, Lansdorp P, Blasco MA (1999) Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice. J Cell Biol 144: 589-601
-
(1999)
J Cell Biol
, vol.144
, pp. 589-601
-
-
Hande, M.P.1
Samper, E.2
Lansdorp, P.3
Blasco, M.A.4
-
76
-
-
0033678847
-
Chromatin remodeling and Rb activity
-
Harbour JW, Dean DC (2000a) Chromatin remodeling and Rb activity. Curr Opin Cell Biol 12: 685-689
-
(2000)
Curr Opin Cell Biol
, vol.12
, pp. 685-689
-
-
Harbour, J.W.1
Dean, D.C.2
-
77
-
-
0034306996
-
The Rb/E2F pathway: Expanding roles and emerging paradigms
-
Harbour JW, Dean DC (2000b) The Rb/E2F pathway: expanding roles and emerging paradigms. Genes Dev 14: 2393-2409
-
(2000)
Genes Dev
, vol.14
, pp. 2393-2409
-
-
Harbour, J.W.1
Dean, D.C.2
-
78
-
-
39749163359
-
Telomerase and cancer therapeutics
-
Harley CB (2008) Telomerase and cancer therapeutics. Nat Rev Cancer 8: 167-179
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 167-179
-
-
Harley, C.B.1
-
79
-
-
0025279931
-
Telomeres shorten during ageing of human fibroblasts
-
Harley CB, Futcher AB, Greider CW (1990) Telomeres shorten during ageing of human fibroblasts. Nature 345: 458-460
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
80
-
-
34447558659
-
piRNAs - the ancient hunters of genome invaders
-
Hartig JV, Tomari Y, Forstemann K (2007) piRNAs - the ancient hunters of genome invaders. Genes Dev 21: 1707-1713
-
(2007)
Genes Dev
, vol.21
, pp. 1707-1713
-
-
Hartig, J.V.1
Tomari, Y.2
Forstemann, K.3
-
81
-
-
0028919756
-
Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: A molecular model for the formation of heterochromatin in yeast
-
Hecht A, Laroche T, Strahl-Bolsinger S, Gasser SM, Grunstein M (1995) Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast. Cell 80: 583-592
-
(1995)
Cell
, vol.80
, pp. 583-592
-
-
Hecht, A.1
Laroche, T.2
Strahl-Bolsinger, S.3
Gasser, S.M.4
Grunstein, M.5
-
82
-
-
33644530693
-
Subtelomeric factors antagonize telomere anchoring and Tell-independent telomere length regulation
-
Hediger F, Berthiau AS, van Houwe G, Gilson E, Gasser SM (2006) Subtelomeric factors antagonize telomere anchoring and Tell-independent telomere length regulation. EMBO J 25: 857-867
-
(2006)
EMBO J
, vol.25
, pp. 857-867
-
-
Hediger, F.1
Berthiau, A.S.2
van Houwe, G.3
Gilson, E.4
Gasser, S.M.5
-
83
-
-
0035812845
-
The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability
-
Hemann MT, Strong MA, Hao LY, Greider CW (2001) The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability. Cell 107: 67-77
-
(2001)
Cell
, vol.107
, pp. 67-77
-
-
Hemann, M.T.1
Strong, M.A.2
Hao, L.Y.3
Greider, C.W.4
-
84
-
-
0343750697
-
Impaired germinal center reaction in mice with short telomeres
-
Herrera E, Martinez AC, Blasco MA (2000) Impaired germinal center reaction in mice with short telomeres. EMBO J 19: 472-481
-
(2000)
EMBO J
, vol.19
, pp. 472-481
-
-
Herrera, E.1
Martinez, A.C.2
Blasco, M.A.3
-
85
-
-
0033153424
-
Disease states associated with telomerase deficiency appear earlier in mice with short telomeres
-
Herrera E, Samper E, Martin-Caballero J, Flores JM, Lee HW, Blasco MA (1999) Disease states associated with telomerase deficiency appear earlier in mice with short telomeres. EMBO J 18: 2950-2960
-
(1999)
EMBO J
, vol.18
, pp. 2950-2960
-
-
Herrera, E.1
Samper, E.2
Martin-Caballero, J.3
Flores, J.M.4
Lee, H.W.5
Blasco, M.A.6
-
86
-
-
0034677535
-
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
-
Imai S, Armstrong CM, Kaeberlein M, Guarente L (2000) Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 403: 795-800
-
(2000)
Nature
, vol.403
, pp. 795-800
-
-
Imai, S.1
Armstrong, C.M.2
Kaeberlein, M.3
Guarente, L.4
-
87
-
-
45349089291
-
Centromere mitotic recombination in mammalian cells
-
Jaco I, Canela A, Vera E, Blasco MA (2008) Centromere mitotic recombination in mammalian cells. J Cell Biol 181: 885-892
-
(2008)
J Cell Biol
, vol.181
, pp. 885-892
-
-
Jaco, I.1
Canela, A.2
Vera, E.3
Blasco, M.A.4
-
88
-
-
0025002966
-
Genetic evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in Saccharomyces cerevisiae
-
Johnson LM, Kayne PS, Kahn ES, Grunstein M (1990) Genetic evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 87: 6286-6290
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 6286-6290
-
-
Johnson, L.M.1
Kayne, P.S.2
Kahn, E.S.3
Grunstein, M.4
-
89
-
-
0347432388
-
Stress-induced transcription of satellite III repeats
-
Jolly C, Metz A, Govin J, Vigneron M, Turner BM, Khochbin S, Vourc'h C (2004) Stress-induced transcription of satellite III repeats. J Cell Biol 164: 25-33
-
(2004)
J Cell Biol
, vol.164
, pp. 25-33
-
-
Jolly, C.1
Metz, A.2
Govin, J.3
Vigneron, M.4
Turner, B.M.5
Khochbin, S.6
Vourc'h, C.7
-
90
-
-
52949107241
-
-
Jones B, Su H, Bhat A, Lei H, Bajko J, Hevi S, Baltus GA, Kadam S, Zhai H, Valdez R, Gonzalo S, Zhang Y, Li E, Chen T (2008) The histone H3K79 methyltransferase DotlL is essential for mammalian development and heterochromatin structure. PLoS Genet 4: e1000190
-
Jones B, Su H, Bhat A, Lei H, Bajko J, Hevi S, Baltus GA, Kadam S, Zhai H, Valdez R, Gonzalo S, Zhang Y, Li E, Chen T (2008) The histone H3K79 methyltransferase DotlL is essential for mammalian development and heterochromatin structure. PLoS Genet 4: e1000190
-
-
-
-
91
-
-
0037470569
-
The fission yeast spSet1p is a histone H3-K4 methyltransferase that functions in telomere maintenance and DNA repair in an ATM kinase Rad3-dependent pathway
-
Kanoh J, Francesconi S, Collura A, Schramke V, Ishikawa F, Baldacci G, Geli V (2003) The fission yeast spSet1p is a histone H3-K4 methyltransferase that functions in telomere maintenance and DNA repair in an ATM kinase Rad3-dependent pathway. J Mol Biol 326: 1081-1094
-
(2003)
J Mol Biol
, vol.326
, pp. 1081-1094
-
-
Kanoh, J.1
Francesconi, S.2
Collura, A.3
Schramke, V.4
Ishikawa, F.5
Baldacci, G.6
Geli, V.7
-
92
-
-
0035899938
-
spRap1 and spRif1, recruited to telomeres by Tazl, are essential for telomere function in fission yeast
-
Kanoh J, Ishikawa F (2001) spRap1 and spRif1, recruited to telomeres by Tazl, are essential for telomere function in fission yeast. Curr Biol 11: 1624-1630
-
(2001)
Curr Biol
, vol.11
, pp. 1624-1630
-
-
Kanoh, J.1
Ishikawa, F.2
-
93
-
-
27144554038
-
Telomere binding protein Tazl establishes Swi6 heterochromatin independently of RNAi at telomeres
-
Kanoh J, Sadaie M, Urano T, Ishikawa F (2005) Telomere binding protein Tazl establishes Swi6 heterochromatin independently of RNAi at telomeres. Curr Biol 15: 1808-1819
-
(2005)
Curr Biol
, vol.15
, pp. 1808-1819
-
-
Kanoh, J.1
Sadaie, M.2
Urano, T.3
Ishikawa, F.4
-
94
-
-
22344434734
-
RNA polymerase II is required for RNAi-dependent heterochromatin assembly
-
Kato H, Goto DB, Martienssen RA, Urano T, Furukawa K, Murakami Y (2005) RNA polymerase II is required for RNAi-dependent heterochromatin assembly. Science 309: 467-469
-
(2005)
Science
, vol.309
, pp. 467-469
-
-
Kato, H.1
Goto, D.B.2
Martienssen, R.A.3
Urano, T.4
Furukawa, K.5
Murakami, Y.6
-
95
-
-
0036843170
-
Chromosomal gradient of histone acetylation established by Sas2p and Sir2p functions as a shield against gene silencing
-
Kimura A, Umehara T, Horikoshi M (2002) Chromosomal gradient of histone acetylation established by Sas2p and Sir2p functions as a shield against gene silencing. Nat Genet 32: 370-377
-
(2002)
Nat Genet
, vol.32
, pp. 370-377
-
-
Kimura, A.1
Umehara, T.2
Horikoshi, M.3
-
96
-
-
0037901839
-
Transcription of mouse DNA methyltransferase 1 (Dnmt1) is regulated by both E2F-Rb-HDAC- dependent and -independent pathways
-
Kimura H, Nakamura T, Ogawa T, Tanaka S, Shiota K (2003) Transcription of mouse DNA methyltransferase 1 (Dnmt1) is regulated by both E2F-Rb-HDAC- dependent and -independent pathways. Nucleic Acids Res 31: 3101-3113
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 3101-3113
-
-
Kimura, H.1
Nakamura, T.2
Ogawa, T.3
Tanaka, S.4
Shiota, K.5
-
97
-
-
34548784928
-
Repeat-associated siRNAs cause chromatin silencing of retrotransposons in the Drosophila melanogaster germline
-
Klenov MS, Lavrov SA, Stolyarenko AD, Ryazansky SS, Aravin AA, Tuschl T, Gvozdev VA (2007) Repeat-associated siRNAs cause chromatin silencing of retrotransposons in the Drosophila melanogaster germline. Nucleic Acids Res 35: 5430-5438
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 5430-5438
-
-
Klenov, M.S.1
Lavrov, S.A.2
Stolyarenko, A.D.3
Ryazansky, S.S.4
Aravin, A.A.5
Tuschl, T.6
Gvozdev, V.A.7
-
98
-
-
0036867444
-
Human telomeric position effect is determined by chromosomal context and telomeric chromatin integrity
-
Koering CE, Pollice A, Zibella MP, Bauwens S, Puisieux A, Brunori M, Brun C, Martins L, Sabatier L, Pulitzer JF, Gilson E (2002) Human telomeric position effect is determined by chromosomal context and telomeric chromatin integrity. EMBO Rep 3: 1055-1061
-
(2002)
EMBO Rep
, vol.3
, pp. 1055-1061
-
-
Koering, C.E.1
Pollice, A.2
Zibella, M.P.3
Bauwens, S.4
Puisieux, A.5
Brunori, M.6
Brun, C.7
Martins, L.8
Sabatier, L.9
Pulitzer, J.F.10
Gilson, E.11
-
99
-
-
0029743764
-
Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats
-
Krauskopf A, Blackburn EH (1996) Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats. Nature 383: 354-357
-
(1996)
Nature
, vol.383
, pp. 354-357
-
-
Krauskopf, A.1
Blackburn, E.H.2
-
100
-
-
41649116098
-
DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes
-
Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Totoki Y, Toyoda A, Ikawa M, Asada N, Kojima K, Yamaguchi Y, Ijiri TW, Hata K, Li E, Matsuda Y, Kimura T, Okabe M, Sakaki Y, Sasaki H, Nakano T (2008) DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes. Genes Dev 22: 908-917
-
(2008)
Genes Dev
, vol.22
, pp. 908-917
-
-
Kuramochi-Miyagawa, S.1
Watanabe, T.2
Gotoh, K.3
Totoki, Y.4
Toyoda, A.5
Ikawa, M.6
Asada, N.7
Kojima, K.8
Yamaguchi, Y.9
Ijiri, T.W.10
Hata, K.11
Li, E.12
Matsuda, Y.13
Kimura, T.14
Okabe, M.15
Sakaki, Y.16
Sasaki, H.17
Nakano, T.18
-
101
-
-
0026657008
-
C-terminal truncation of RAP1 results in the deregulation of telomere size, stability, and function in Saccharomyces cerevisiae
-
Kyrion G, Boakye KA, Lustig AJ (1992) C-terminal truncation of RAP1 results in the deregulation of telomere size, stability, and function in Saccharomyces cerevisiae. Mol Cell Biol 12: 5159-5173
-
(1992)
Mol Cell Biol
, vol.12
, pp. 5159-5173
-
-
Kyrion, G.1
Boakye, K.A.2
Lustig, A.J.3
-
102
-
-
0035282573
-
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
-
Lachner M, O'Carroll D, Rea S, Mechtler K, Jenuwein T (2001) Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature 410: 116-120
-
(2001)
Nature
, vol.410
, pp. 116-120
-
-
Lachner, M.1
O'Carroll, D.2
Rea, S.3
Mechtler, K.4
Jenuwein, T.5
-
103
-
-
0034725085
-
Extension of cell life-span and telomere length in animals cloned from senescent somatic cells
-
Lanza RP, Cibelli JB, Blackwell C, Cristofalo VJ, Francis MK, Baerlocher GM, Mak J, Schertzer M, Chavez EA, Sawyer N, Lansdorp PM, West MD (2000) Extension of cell life-span and telomere length in animals cloned from senescent somatic cells. Science 288: 665-669
-
(2000)
Science
, vol.288
, pp. 665-669
-
-
Lanza, R.P.1
Cibelli, J.B.2
Blackwell, C.3
Cristofalo, V.J.4
Francis, M.K.5
Baerlocher, G.M.6
Mak, J.7
Schertzer, M.8
Chavez, E.A.9
Sawyer, N.10
Lansdorp, P.M.11
West, M.D.12
-
104
-
-
10744230544
-
Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin
-
Lehnertz B, Ueda Y, Derijck AA, Braunschweig U, Perez-Burgos L, Kubicek S, Chen T, Li E, Jenuwein T, Peters AH (2003) Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin. Curr Biol 13: 1192-1200
-
(2003)
Curr Biol
, vol.13
, pp. 1192-1200
-
-
Lehnertz, B.1
Ueda, Y.2
Derijck, A.A.3
Braunschweig, U.4
Perez-Burgos, L.5
Kubicek, S.6
Chen, T.7
Li, E.8
Jenuwein, T.9
Peters, A.H.10
-
105
-
-
0027145631
-
Transposons in place of telomeric repeats at a Drosophila telomere
-
Levis RW, Ganesan R, Houtchens K, Tolar LA, Sheen FM (1993) Transposons in place of telomeric repeats at a Drosophila telomere. Cell 75: 1083-1093
-
(1993)
Cell
, vol.75
, pp. 1083-1093
-
-
Levis, R.W.1
Ganesan, R.2
Houtchens, K.3
Tolar, L.A.4
Sheen, F.M.5
-
106
-
-
10044265469
-
Counting of Rif1p and Rif2p on Saccharomyces cerevisiae telomeres regulates telomere length
-
Levy DL, Blackburn EH (2004) Counting of Rif1p and Rif2p on Saccharomyces cerevisiae telomeres regulates telomere length. Mol Cell Biol 24: 10857-10867
-
(2004)
Mol Cell Biol
, vol.24
, pp. 10857-10867
-
-
Levy, D.L.1
Blackburn, E.H.2
-
107
-
-
19344377042
-
Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, a product of NAD-dependent histone deacetylation
-
Liou GG, Tanny JC, Kruger RG, Walz T, Moazed D (2005) Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, a product of NAD-dependent histone deacetylation. Cell 121: 515-527
-
(2005)
Cell
, vol.121
, pp. 515-527
-
-
Liou, G.G.1
Tanny, J.C.2
Kruger, R.G.3
Walz, T.4
Moazed, D.5
-
108
-
-
0033590071
-
The retinoblastoma gene family in differentiation and development
-
Lipinski MM, Jacks T (1999) The retinoblastoma gene family in differentiation and development. Oncogene 18: 7873-7882
-
(1999)
Oncogene
, vol.18
, pp. 7873-7882
-
-
Lipinski, M.M.1
Jacks, T.2
-
109
-
-
36749034760
-
Telomere lengthening early in development
-
Liu L, Bailey SM, Okuka M, Munoz P, Li C, Zhou L, Wu C, Czerwiec E, Sandier L, Seyfang A, Blasco MA, Keefe DL (2007) Telomere lengthening early in development. Nat Cell Biol 9: 1436-1441
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1436-1441
-
-
Liu, L.1
Bailey, S.M.2
Okuka, M.3
Munoz, P.4
Li, C.5
Zhou, L.6
Wu, C.7
Czerwiec, E.8
Sandier, L.9
Seyfang, A.10
Blasco, M.A.11
Keefe, D.L.12
-
110
-
-
0029417194
-
The chromosome ends of Saccharomyces cerevisiae
-
Louis EJ (1995) The chromosome ends of Saccharomyces cerevisiae. Yeast 11: 1553-1573
-
(1995)
Yeast
, vol.11
, pp. 1553-1573
-
-
Louis, E.J.1
-
111
-
-
55949106494
-
The Rat1p 5′ to 3′ exonuclease degrades telomeric repeat-containing RNA and promotes telomere elongation in Saccharomyces cerevisiae
-
Luke B, Panza A, Redon S, Iglesias N, Li Z, Lingner J (2008) The Rat1p 5′ to 3′ exonuclease degrades telomeric repeat-containing RNA and promotes telomere elongation in Saccharomyces cerevisiae. Mol Cell 32: 465-477
-
(2008)
Mol Cell
, vol.32
, pp. 465-477
-
-
Luke, B.1
Panza, A.2
Redon, S.3
Iglesias, N.4
Li, Z.5
Lingner, J.6
-
112
-
-
34249909232
-
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution
-
Maherali N, Sridharan R, Xie W, Utikal J, Eminli S, Arnold K, Stadtfeld M, Yachechko R, Tchieu J, Jaenisch R, Plath K, Hochedlinger K (2007) Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell 1: 55-70
-
(2007)
Cell Stem Cell
, vol.1
, pp. 55-70
-
-
Maherali, N.1
Sridharan, R.2
Xie, W.3
Utikal, J.4
Eminli, S.5
Arnold, K.6
Stadtfeld, M.7
Yachechko, R.8
Tchieu, J.9
Jaenisch, R.10
Plath, K.11
Hochedlinger, K.12
-
113
-
-
0029746494
-
Evidence for silencing compartments within the yeast nucleus: A role for telomere proximity and Sir protein concentration in silencer-mediated repression
-
Maillet L, Boscheron C, Gotta M, Marcand S, Gilson E, Gasser SM (1996) Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression. Genes Dev 10: 1796-1811
-
(1996)
Genes Dev
, vol.10
, pp. 1796-1811
-
-
Maillet, L.1
Boscheron, C.2
Gotta, M.3
Marcand, S.4
Gilson, E.5
Gasser, S.M.6
-
114
-
-
0032079514
-
Suppression of crossing-over by DNA methylation in Ascobolus
-
Maloisel L, Rossignol JL (1998) Suppression of crossing-over by DNA methylation in Ascobolus. Genes Dev 12: 1381-1389
-
(1998)
Genes Dev
, vol.12
, pp. 1381-1389
-
-
Maloisel, L.1
Rossignol, J.L.2
-
115
-
-
0033564210
-
Progressive cis-inhibition of telomerase upon telomere elongation
-
Marcand S, Brevet V, Gilson E (1999) Progressive cis-inhibition of telomerase upon telomere elongation. EMBO J 18: 3509-3519
-
(1999)
EMBO J
, vol.18
, pp. 3509-3519
-
-
Marcand, S.1
Brevet, V.2
Gilson, E.3
-
116
-
-
0031036351
-
A protein-counting mechanism for telomere length regulation in yeast
-
Marcand S, Gilson E, Shore D (1997) A protein-counting mechanism for telomere length regulation in yeast. Science 275: 986-990
-
(1997)
Science
, vol.275
, pp. 986-990
-
-
Marcand, S.1
Gilson, E.2
Shore, D.3
-
117
-
-
58949094552
-
Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells
-
Marion RM, Strati K, Li H, Tejera A, Schoeftner S, Ortega S, Serrano M, Blasco MA (2009) Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells. Cell Stem Cell 4: 141-154
-
(2009)
Cell Stem Cell
, vol.4
, pp. 141-154
-
-
Marion, R.M.1
Strati, K.2
Li, H.3
Tejera, A.4
Schoeftner, S.5
Ortega, S.6
Serrano, M.7
Blasco, M.A.8
-
118
-
-
67749143935
-
Structure of propeller-type parallel-stranded RNA G-quadruplexes, formed by human telomeric RNA sequences in K+ solution
-
Martadinata H, Phan AT (2009) Structure of propeller-type parallel-stranded RNA G-quadruplexes, formed by human telomeric RNA sequences in K+ solution. J Am Chem Soc 131: 2570-2578
-
(2009)
J Am Chem Soc
, vol.131
, pp. 2570-2578
-
-
Martadinata, H.1
Phan, A.T.2
-
119
-
-
59649090017
-
Reconstitution of yeast silent chromatin: Multiple contact sites and O-AADPR binding load SIR complexes onto nucleosomes in vitro
-
Martino F, Kueng S, Robinson P, Tsai-Pflugfelder M, van Leeuwen F, Ziegler M, Cubizolles F, Cockell MM, Rhodes D, Gasser SM (2009) Reconstitution of yeast silent chromatin: multiple contact sites and O-AADPR binding load SIR complexes onto nucleosomes in vitro. Mol Cell 33: 323-334
-
(2009)
Mol Cell
, vol.33
, pp. 323-334
-
-
Martino, F.1
Kueng, S.2
Robinson, P.3
Tsai-Pflugfelder, M.4
van Leeuwen, F.5
Ziegler, M.6
Cubizolles, F.7
Cockell, M.M.8
Rhodes, D.9
Gasser, S.M.10
-
120
-
-
0028959218
-
The unusual telomeres of Drosophila
-
Mason JM, Biessmann H (1995) The unusual telomeres of Drosophila. Trends Genet 11: 58-62
-
(1995)
Trends Genet
, vol.11
, pp. 58-62
-
-
Mason, J.M.1
Biessmann, H.2
-
121
-
-
38049080704
-
Drosophila telomeres: An exception providing new insights
-
Mason JM, Frydrychova RC, Biessmann H (2008) Drosophila telomeres: an exception providing new insights. Bioessays 30: 25-37
-
(2008)
Bioessays
, vol.30
, pp. 25-37
-
-
Mason, J.M.1
Frydrychova, R.C.2
Biessmann, H.3
-
122
-
-
10844286385
-
A deficiency screen for dominant suppressors of telomeric silencing in Drosophila
-
Mason JM, Ransom J, Konev AY (2004) A deficiency screen for dominant suppressors of telomeric silencing in Drosophila. Genetics 168: 1353-1370
-
(2004)
Genetics
, vol.168
, pp. 1353-1370
-
-
Mason, J.M.1
Ransom, J.2
Konev, A.Y.3
-
123
-
-
18044373421
-
Dyskeratosis congenita - a disease of dysfunctional telomere maintenance
-
Mason PJ, Wilson DB, Bessler M (2005) Dyskeratosis congenita - a disease of dysfunctional telomere maintenance. Curr Mol Med 5: 159-170
-
(2005)
Curr Mol Med
, vol.5
, pp. 159-170
-
-
Mason, P.J.1
Wilson, D.B.2
Bessler, M.3
-
124
-
-
18144419362
-
Regulation of DNA methyltransferase 1 by the pRb/E2Fl pathway
-
McCabe MT, Davis JN, Day ML (2005) Regulation of DNA methyltransferase 1 by the pRb/E2Fl pathway. Cancer Res 65: 3624-3632
-
(2005)
Cancer Res
, vol.65
, pp. 3624-3632
-
-
McCabe, M.T.1
Davis, J.N.2
Day, M.L.3
-
125
-
-
0037423930
-
Conserved histone variant H2A. Z protects euchromatin from the ectopic spread of silent heterochromatin
-
Meneghini MD, Wu M, Madhani HD (2003) Conserved histone variant H2A. Z protects euchromatin from the ectopic spread of silent heterochromatin. Cell 112: 725-736
-
(2003)
Cell
, vol.112
, pp. 725-736
-
-
Meneghini, M.D.1
Wu, M.2
Madhani, H.D.3
-
126
-
-
41349090663
-
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
-
Michishita E, McCord RA, Berber E, Kioi M, Padilla-Nash H, Damian M, Cheung P, Kusumoto R, Kawahara TL, Barrett JC, Chang HY, Bohr VA, Ried T, Gozani O, Chua KF (2008) SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature 452: 492-496
-
(2008)
Nature
, vol.452
, pp. 492-496
-
-
Michishita, E.1
McCord, R.A.2
Berber, E.3
Kioi, M.4
Padilla-Nash, H.5
Damian, M.6
Cheung, P.7
Kusumoto, R.8
Kawahara, T.L.9
Barrett, J.C.10
Chang, H.Y.11
Bohr, V.A.12
Ried, T.13
Gozani, O.14
Chua, K.F.15
-
127
-
-
45549090631
-
Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length
-
Miyoshi T, Kanoh J, Saito M, Ishikawa F (2008) Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length. Science 320: 1341-1344
-
(2008)
Science
, vol.320
, pp. 1341-1344
-
-
Miyoshi, T.1
Kanoh, J.2
Saito, M.3
Ishikawa, F.4
-
128
-
-
10944248935
-
Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs
-
Motamedi MR, Verdel A, Colmenares SU, Gerber SA, Gygi SP, Moazed D (2004) Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs. Cell 119: 789-802
-
(2004)
Cell
, vol.119
, pp. 789-802
-
-
Motamedi, M.R.1
Verdel, A.2
Colmenares, S.U.3
Gerber, S.A.4
Gygi, S.P.5
Moazed, D.6
-
129
-
-
27744527486
-
The first molecular details of ALT in human tumor cells
-
Muntoni A, Reddel RR (2005) The first molecular details of ALT in human tumor cells. Hum Mol Genet 14(Spec No. 2): R191-R196
-
(2005)
Hum Mol Genet
, vol.14
, Issue.SPEC 2
-
-
Muntoni, A.1
Reddel, R.R.2
-
130
-
-
38049028459
-
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
-
Nakagawa M, Koyanagi M, Tanabe K, Takahashi K, Ichisaka T, Aoi T, Okita K, Mochiduki Y, Takizawa N, Yamanaka S (2008) Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol 26: 101-106
-
(2008)
Nat Biotechnol
, vol.26
, pp. 101-106
-
-
Nakagawa, M.1
Koyanagi, M.2
Tanabe, K.3
Takahashi, K.4
Ichisaka, T.5
Aoi, T.6
Okita, K.7
Mochiduki, Y.8
Takizawa, N.9
Yamanaka, S.10
-
131
-
-
0034724537
-
A chromodomain protein, Swi6, performs imprinting functions in fission yeast during mitosis and meiosis
-
Nakayama J, Klar AJ, Grewal SI (2000) A chromodomain protein, Swi6, performs imprinting functions in fission yeast during mitosis and meiosis. Cell 101: 307-317
-
(2000)
Cell
, vol.101
, pp. 307-317
-
-
Nakayama, J.1
Klar, A.J.2
Grewal, S.I.3
-
132
-
-
0035815360
-
Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly
-
Nakayama J, Rice JC, Strahl BD, Allis CD, Grewal SI (2001) Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly. Science 292: 110-113
-
(2001)
Science
, vol.292
, pp. 110-113
-
-
Nakayama, J.1
Rice, J.C.2
Strahl, B.D.3
Allis, C.D.4
Grewal, S.I.5
-
133
-
-
0037098044
-
Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association
-
Ng HH, Feng Q, Wang H, Erdjument-Bromage H, Tempst P, Zhang Y, Struhl K (2002a) Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association. Genes Dev 16: 1518-1527
-
(2002)
Genes Dev
, vol.16
, pp. 1518-1527
-
-
Ng, H.H.1
Feng, Q.2
Wang, H.3
Erdjument-Bromage, H.4
Tempst, P.5
Zhang, Y.6
Struhl, K.7
-
134
-
-
0037144393
-
Ubiquitination of histone H2B by Rad6 is required for efficient Dot1-mediated methylation of histone H3 lysine 79
-
Ng HH, Xu RM, Zhang Y, Struhl K (2002b) Ubiquitination of histone H2B by Rad6 is required for efficient Dot1-mediated methylation of histone H3 lysine 79. J Biol Chem 277: 34655-34657
-
(2002)
J Biol Chem
, vol.277
, pp. 34655-34657
-
-
Ng, H.H.1
Xu, R.M.2
Zhang, Y.3
Struhl, K.4
-
135
-
-
0034077143
-
Telomere maintenance in telomerase-deficient mouse embryonic stem cells: Characterization of an amplified telomeric DNA
-
Niida H, Shinkai Y, Hande MP, Matsumoto T, Takehara S, Tachibana M, Oshimura M, Lansdorp PM, Furuichi Y (2000) Telomere maintenance in telomerase-deficient mouse embryonic stem cells: characterization of an amplified telomeric DNA. Mol Cell Biol 20: 4115-4127
-
(2000)
Mol Cell Biol
, vol.20
, pp. 4115-4127
-
-
Niida, H.1
Shinkai, Y.2
Hande, M.P.3
Matsumoto, T.4
Takehara, S.5
Tachibana, M.6
Oshimura, M.7
Lansdorp, P.M.8
Furuichi, Y.9
-
136
-
-
0032560102
-
Defective meiosis in telomere-silencing mutants of Schizosaccharomyces pombe
-
Nimmo ER, Pidoux AL, Perry PE, Allshire RC (1998) Defective meiosis in telomere-silencing mutants of Schizosaccharomyces pombe. Nature 392: 825-828
-
(1998)
Nature
, vol.392
, pp. 825-828
-
-
Nimmo, E.R.1
Pidoux, A.L.2
Perry, P.E.3
Allshire, R.C.4
-
137
-
-
0030668324
-
SET1, a yeast member of the trithorax family, functions in transcriptional silencing and diverse cellular processes
-
Nislow C, Ray E, Pillus L (1997) SET1, a yeast member of the trithorax family, functions in transcriptional silencing and diverse cellular processes. Mol Biol Cell 8: 2421-2436
-
(1997)
Mol Biol Cell
, vol.8
, pp. 2421-2436
-
-
Nislow, C.1
Ray, E.2
Pillus, L.3
-
138
-
-
10644221797
-
RITS acts in cis to promote RNA interference-mediated transcriptional and post-transcriptional silencing
-
Noma K, Sugiyama T, Cam H, Verdel A, Zofall M, Jia S, Moazed D, Grewal SI (2004) RITS acts in cis to promote RNA interference-mediated transcriptional and post-transcriptional silencing. Nat Genet 36: 1174-1180
-
(2004)
Nat Genet
, vol.36
, pp. 1174-1180
-
-
Noma, K.1
Sugiyama, T.2
Cam, H.3
Verdel, A.4
Zofall, M.5
Jia, S.6
Moazed, D.7
Grewal, S.I.8
-
139
-
-
56749156405
-
SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging
-
Oberdoerffer P, Michan S, McVay M, Mostoslavsky R, Vann J, Park SK, Hartlerode A, Stegmuller J, Hafner A, Loerch P, Wright SM, Mills KD, Bonni A, Yankner BA, Scully R, Prolla TA, Alt FW, Sinclair DA (2008) SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell 135: 907-918
-
(2008)
Cell
, vol.135
, pp. 907-918
-
-
Oberdoerffer, P.1
Michan, S.2
McVay, M.3
Mostoslavsky, R.4
Vann, J.5
Park, S.K.6
Hartlerode, A.7
Stegmuller, J.8
Hafner, A.9
Loerch, P.10
Wright, S.M.11
Mills, K.D.12
Bonni, A.13
Yankner, B.A.14
Scully, R.15
Prolla, T.A.16
Alt, F.W.17
Sinclair, D.A.18
-
140
-
-
33646946743
-
Epigenetic telomere protection by Drosophila DNA damage response pathways
-
Oikemus SR, Queiroz-Machado J, Lai K, McGinnis N, Sunkel C, Brodsky MH (2006) Epigenetic telomere protection by Drosophila DNA damage response pathways. PLoS Genet 2: e71
-
(2006)
PLoS Genet
, vol.2
-
-
Oikemus, S.R.1
Queiroz-Machado, J.2
Lai, K.3
McGinnis, N.4
Sunkel, C.5
Brodsky, M.H.6
-
141
-
-
0031860739
-
Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltrans-ferases
-
Okano M, Xie S, Li E (1998) Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltrans-ferases. Nat Genet 19: 219-220
-
(1998)
Nat Genet
, vol.19
, pp. 219-220
-
-
Okano, M.1
Xie, S.2
Li, E.3
-
142
-
-
0035576789
-
The yeast SAS (something about silencing) protein complex contains a MYST-type putative acetyltransferase and functions with chromatin assembly factor ASF1
-
Osada S, Sutton A, Muster N, Brown CE, Yates III JR, Sternglanz R, Workman JL (2001) The yeast SAS (something about silencing) protein complex contains a MYST-type putative acetyltransferase and functions with chromatin assembly factor ASF1. Genes Dev 15: 3155-3168
-
(2001)
Genes Dev
, vol.15
, pp. 3155-3168
-
-
Osada, S.1
Sutton, A.2
Muster, N.3
Brown, C.E.4
Yates III, J.R.5
Sternglanz, R.6
Workman, J.L.7
-
143
-
-
46249125488
-
How shelterin protects mammalian telomeres
-
Palm W, de Lange T (2008) How shelterin protects mammalian telomeres. Annu Rev Genet 42: 301-334
-
(2008)
Annu Rev Genet
, vol.42
, pp. 301-334
-
-
Palm, W.1
de Lange, T.2
-
144
-
-
0027423154
-
SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres
-
Palladino F, Laroche T, Gilson E, Axelrod A, Pillus L, Gasser SM (1993) SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres. Cell 75: 543-555
-
(1993)
Cell
, vol.75
, pp. 543-555
-
-
Palladino, F.1
Laroche, T.2
Gilson, E.3
Axelrod, A.4
Pillus, L.5
Gasser, S.M.6
-
145
-
-
54049138948
-
Kcnqlotl antisense noncoding RNA mediates lineage-specific transcriptional silencing through chromatin-level regulation
-
Pandey RR, Mondal T, Mohammad F, Enroth S, Redrup L, Komorowski J, Nagano T, Mancini-Dinardo D, Kanduri C (2008) Kcnqlotl antisense noncoding RNA mediates lineage-specific transcriptional silencing through chromatin-level regulation. Mol Cell 32: 232-246
-
(2008)
Mol Cell
, vol.32
, pp. 232-246
-
-
Pandey, R.R.1
Mondal, T.2
Mohammad, F.3
Enroth, S.4
Redrup, L.5
Komorowski, J.6
Nagano, T.7
Mancini-Dinardo, D.8
Kanduri, C.9
-
146
-
-
0346786214
-
Retrotransposons provide an evolutionarily robust non-telomerase mechanism to maintain telomeres
-
Pardue ML, DeBaryshe PG (2003) Retrotransposons provide an evolutionarily robust non-telomerase mechanism to maintain telomeres. Annu Rev Genet 37: 485-511
-
(2003)
Annu Rev Genet
, vol.37
, pp. 485-511
-
-
Pardue, M.L.1
DeBaryshe, P.G.2
-
147
-
-
61849111590
-
Drosophila telomeres: A variation on the telomerase theme
-
Pardue ML, Debaryshe PG (2008) Drosophila telomeres: a variation on the telomerase theme. Fly (Austin) 2: 101-110
-
(2008)
Fly (Austin)
, vol.2
, pp. 101-110
-
-
Pardue, M.L.1
Debaryshe, P.G.2
-
148
-
-
23944501376
-
Two retrotransposons maintain telomeres in Drosophila
-
Pardue ML, Rashkova S, Casacuberta E, DeBaryshe PG, George JA, Traverse KL (2005) Two retrotransposons maintain telomeres in Drosophila. Chromosome Res 13: 443-453
-
(2005)
Chromosome Res
, vol.13
, pp. 443-453
-
-
Pardue, M.L.1
Rashkova, S.2
Casacuberta, E.3
DeBaryshe, P.G.4
George, J.A.5
Traverse, K.L.6
-
149
-
-
0036789523
-
A core nucleosome surface crucial for transcriptional silencing
-
Park JH, Cosgrove MS, Youngman E, Wolberger C, Boeke JD (2002) A core nucleosome surface crucial for transcriptional silencing. Nat Genet 32: 273-279
-
(2002)
Nat Genet
, vol.32
, pp. 273-279
-
-
Park, J.H.1
Cosgrove, M.S.2
Youngman, E.3
Wolberger, C.4
Boeke, J.D.5
-
150
-
-
34249099120
-
Silencing by imprinted noncoding RNAs: Is transcription the answer?
-
Pauler FM, Koerner MV, Barlow DP (2007) Silencing by imprinted noncoding RNAs: is transcription the answer? Trends Genet 23: 284-292
-
(2007)
Trends Genet
, vol.23
, pp. 284-292
-
-
Pauler, F.M.1
Koerner, M.V.2
Barlow, D.P.3
-
151
-
-
58549109636
-
X chromosome dosage compensation: How mammals keep the balance
-
Payer B, Lee JT (2008) X chromosome dosage compensation: how mammals keep the balance. Anna. Rev Genet 42: 733-772
-
(2008)
Anna. Rev Genet
, vol.42
, pp. 733-772
-
-
Payer, B.1
Lee, J.T.2
-
152
-
-
33644502519
-
Telomere position effect and silencing of transgenes near telomeres in the mouse
-
Pedram M, Sprung CN, Gao Q, Lo AW, Reynolds GE, Murnane JP (2006) Telomere position effect and silencing of transgenes near telomeres in the mouse. Mol Cell Biol 26: 1865-1878
-
(2006)
Mol Cell Biol
, vol.26
, pp. 1865-1878
-
-
Pedram, M.1
Sprung, C.N.2
Gao, Q.3
Lo, A.W.4
Reynolds, G.E.5
Murnane, J.P.6
-
153
-
-
4143116771
-
HP1 controls telomere capping, telomere elongation, and telomere silencing by two different mechanisms in Drosophila
-
Perrini B, Piacentini L, Fanti L, Altieri F, Chichiarelli S, Berloco M, Turano C, Ferraro A, Pimpinelli S (2004) HP1 controls telomere capping, telomere elongation, and telomere silencing by two different mechanisms in Drosophila. Mol Cell 15: 467-476
-
(2004)
Mol Cell
, vol.15
, pp. 467-476
-
-
Perrini, B.1
Piacentini, L.2
Fanti, L.3
Altieri, F.4
Chichiarelli, S.5
Berloco, M.6
Turano, C.7
Ferraro, A.8
Pimpinelli, S.9
-
154
-
-
9144268924
-
Partitioning and plasticity of repressive histone methylation states in mammalian chromatin
-
Peters AH, Kubicek S, Mechtler K, O'Sullivan RJ, Derijck AA, Perez-Burgos L, Kohlmaier A, Opravil S, Tachibana M, Shinkai Y, Martens JH, Jenuwein T (2003) Partitioning and plasticity of repressive histone methylation states in mammalian chromatin. Mol Cell 12: 1577-1589
-
(2003)
Mol Cell
, vol.12
, pp. 1577-1589
-
-
Peters, A.H.1
Kubicek, S.2
Mechtler, K.3
O'Sullivan, R.J.4
Derijck, A.A.5
Perez-Burgos, L.6
Kohlmaier, A.7
Opravil, S.8
Tachibana, M.9
Shinkai, Y.10
Martens, J.H.11
Jenuwein, T.12
-
155
-
-
17944380227
-
Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability
-
Peters AH, O'Carroll D, Scherthan H, Mechtler K, Sauer S, Schofer C, Weipoltshammer K, Pagani M, Lachner M, Kohlmaier A, Opravil S, Doyle M, Sibilia M, Jenuwein T (2001) Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability. Cell 107: 323-337
-
(2001)
Cell
, vol.107
, pp. 323-337
-
-
Peters, A.H.1
O'Carroll, D.2
Scherthan, H.3
Mechtler, K.4
Sauer, S.5
Schofer, C.6
Weipoltshammer, K.7
Pagani, M.8
Lachner, M.9
Kohlmaier, A.10
Opravil, S.11
Doyle, M.12
Sibilia, M.13
Jenuwein, T.14
-
156
-
-
33646142159
-
Histone H3 lysine 9 and H4 lysine 20 trimethylation and the expression of Suv4-20h2 and Suv-39hl histone methyltransferases in hepatocarcinogenesis induced by methyl deficiency in rats
-
Pogribny IP, Ross SA, Tryndyak VP, Pogribna M, Poirier LA, Karpinets TV (2006) Histone H3 lysine 9 and H4 lysine 20 trimethylation and the expression of Suv4-20h2 and Suv-39hl histone methyltransferases in hepatocarcinogenesis induced by methyl deficiency in rats. Carcinogenesis 27: 1180-1186
-
(2006)
Carcinogenesis
, vol.27
, pp. 1180-1186
-
-
Pogribny, I.P.1
Ross, S.A.2
Tryndyak, V.P.3
Pogribna, M.4
Poirier, L.A.5
Karpinets, T.V.6
-
157
-
-
0029919650
-
The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae
-
Porter SE, Greenwell PW, Ritchie KB, Petes TD (1996) The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae. Nucleic Acids Res 24: 582-585
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 582-585
-
-
Porter, S.E.1
Greenwell, P.W.2
Ritchie, K.B.3
Petes, T.D.4
-
158
-
-
60549097506
-
The Drosophila modigliani (moi) gene encodes a HOAP-interacting protein required for telomere protection
-
Raffa GD, Siriaco G, Cugusi S, Ciapponi L, Cenci G, Wojcik E, Gatti M (2009) The Drosophila modigliani (moi) gene encodes a HOAP-interacting protein required for telomere protection. Proc Natl Acad Sci USA 106: 2271-2276
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2271-2276
-
-
Raffa, G.D.1
Siriaco, G.2
Cugusi, S.3
Ciapponi, L.4
Cenci, G.5
Wojcik, E.6
Gatti, M.7
-
159
-
-
67649756727
-
Structure of long telomeric RNA transcripts: The G-rich RNA forms a compact repeating structure containing G-quartets
-
Randall A, Griffith JD (2009) Structure of long telomeric RNA transcripts: the G-rich RNA forms a compact repeating structure containing G-quartets. J Biol Chem 284: 13980-13986
-
(2009)
J Biol Chem
, vol.284
, pp. 13980-13986
-
-
Randall, A.1
Griffith, J.D.2
-
160
-
-
0037072660
-
Small RNAs correspond to centromereheterochromatic repeats
-
Reinhart BJ, Bartel DP (2002) Small RNAs correspond to centromereheterochromatic repeats. Science 297: 1831
-
(2002)
Science
, vol.297
, pp. 1831
-
-
Reinhart, B.J.1
Bartel, D.P.2
-
162
-
-
0742270643
-
Transcriptional activation of a constitutive heterochromatic domain of the human genome in response to heat shock
-
Rizzi N, Denegri M, Chiodi I, Corioni M, Valgardsdottir R, Cobianchi F, Riva S, Biamonti G (2004) Transcriptional activation of a constitutive heterochromatic domain of the human genome in response to heat shock. Mol Biol Cell 15: 543-551
-
(2004)
Mol Biol Cell
, vol.15
, pp. 543-551
-
-
Rizzi, N.1
Denegri, M.2
Chiodi, I.3
Corioni, M.4
Valgardsdottir, R.5
Cobianchi, F.6
Riva, S.7
Biamonti, G.8
-
163
-
-
0033525558
-
Longevity, stress response, and cancer in aging telomerase-deficient mice
-
Rudolph KL, Chang S, Lee HW, Blasco M, Gottlieb GJ, Greider C, DePinho RA (1999) Longevity, stress response, and cancer in aging telomerase-deficient mice. Cell 96: 701-712
-
(1999)
Cell
, vol.96
, pp. 701-712
-
-
Rudolph, K.L.1
Chang, S.2
Lee, H.W.3
Blasco, M.4
Gottlieb, G.J.5
Greider, C.6
DePinho, R.A.7
-
164
-
-
33747369856
-
Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome
-
Saito K, Nishida KM, Mori T, Kawamura Y, Miyoshi K, Nagami T, Siomi H, Siomi MC (2006) Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome. Genes Dev 20: 2214-2222
-
(2006)
Genes Dev
, vol.20
, pp. 2214-2222
-
-
Saito, K.1
Nishida, K.M.2
Mori, T.3
Kawamura, Y.4
Miyoshi, K.5
Nagami, T.6
Siomi, H.7
Siomi, M.C.8
-
165
-
-
0034769105
-
Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres
-
Samper E, Flores JM, Blasco MA (2001) Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres. EMBO Rep 2: 800-807
-
(2001)
EMBO Rep
, vol.2
, pp. 800-807
-
-
Samper, E.1
Flores, J.M.2
Blasco, M.A.3
-
166
-
-
0033786367
-
Role for the silencing protein Dotl in meiotic checkpoint control
-
San-Segundo PA, Roeder GS (2000) Role for the silencing protein Dotl in meiotic checkpoint control. Mol Biol Cell 11: 3601-3615
-
(2000)
Mol Biol Cell
, vol.11
, pp. 3601-3615
-
-
San-Segundo, P.A.1
Roeder, G.S.2
-
167
-
-
23944516520
-
Conditional telomerase induction causes proliferation of hair follicle stem cells
-
Sarin KY, Cheung P, Gilison D, Lee E, Tennen RI, Wang E, Artandi MK, Oro AE, Artandi SE (2005) Conditional telomerase induction causes proliferation of hair follicle stem cells. Nature 436: 1048-1052
-
(2005)
Nature
, vol.436
, pp. 1048-1052
-
-
Sarin, K.Y.1
Cheung, P.2
Gilison, D.3
Lee, E.4
Tennen, R.I.5
Wang, E.6
Artandi, M.K.7
Oro, A.E.8
Artandi, S.E.9
-
168
-
-
0036236976
-
Heterochromatin protein 1 is involved in control of telomere elongation in Drosophila melanogaster
-
Savitsky M, Kravchuk O, Melnikova L, Georgiev P (2002) Heterochromatin protein 1 is involved in control of telomere elongation in Drosophila melanogaster. Mol Cell Biol 22: 3204-3218
-
(2002)
Mol Cell Biol
, vol.22
, pp. 3204-3218
-
-
Savitsky, M.1
Kravchuk, O.2
Melnikova, L.3
Georgiev, P.4
-
169
-
-
32044437792
-
Telomere elongation is under the control of the RNAi-based mechanism in the Drosophila germline
-
Savitsky M, Kwon D, Georgiev P, Kalmykova A, Gvozdev V (2006) Telomere elongation is under the control of the RNAi-based mechanism in the Drosophila germline. Genes Dev 20: 345-354
-
(2006)
Genes Dev
, vol.20
, pp. 345-354
-
-
Savitsky, M.1
Kwon, D.2
Georgiev, P.3
Kalmykova, A.4
Gvozdev, V.5
-
170
-
-
2542593234
-
Telomere length is reset during early mammalian embryogenesis
-
Schaetzlein S, Lucas-Hahn A, Lemme E, Kues WA, Dorsch M, Manns MP, Niemann H, Rudolph KL (2004) Telomere length is reset during early mammalian embryogenesis. Proc Natl Acad Sci USA 101: 8034-8038
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 8034-8038
-
-
Schaetzlein, S.1
Lucas-Hahn, A.2
Lemme, E.3
Kues, W.A.4
Dorsch, M.5
Manns, M.P.6
Niemann, H.7
Rudolph, K.L.8
-
171
-
-
38849111756
-
Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II
-
Schoeftner S, Blasco MA (2008) Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II. Nat Cell Biol 10: 228-236
-
(2008)
Nat Cell Biol
, vol.10
, pp. 228-236
-
-
Schoeftner, S.1
Blasco, M.A.2
-
172
-
-
2642542643
-
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin
-
Schotta G, Lachner M, Sarma K, Ebert A, Sengupta R, Reuter G, Reinberg D, Jenuwein T (2004) A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Genes Dev 18: 1251-1262
-
(2004)
Genes Dev
, vol.18
, pp. 1251-1262
-
-
Schotta, G.1
Lachner, M.2
Sarma, K.3
Ebert, A.4
Sengupta, R.5
Reuter, G.6
Reinberg, D.7
Jenuwein, T.8
-
173
-
-
48749102722
-
A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse
-
Schotta G, Sengupta R, Kubicek S, Malin S, Kauer M, Callen E, Celeste A, Pagani M, Opravil S, De La Rosa-Velazquez IA, Espejo A, Bedford MT, Nussenzweig A, Busslinger M, Jenuwein T (2008) A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse. Genes Dev 22: 2048-2061
-
(2008)
Genes Dev
, vol.22
, pp. 2048-2061
-
-
Schotta, G.1
Sengupta, R.2
Kubicek, S.3
Malin, S.4
Kauer, M.5
Callen, E.6
Celeste, A.7
Pagani, M.8
Opravil, S.9
De La Rosa-Velazquez, I.A.10
Espejo, A.11
Bedford, M.T.12
Nussenzweig, A.13
Busslinger, M.14
Jenuwein, T.15
-
174
-
-
22544461653
-
Histone H2B ubiquitylation controls processive methylation but not monomethylation by Dotl and Setl
-
Shahbazian MD, Zhang K, Grunstein M (2005) Histone H2B ubiquitylation controls processive methylation but not monomethylation by Dotl and Setl. Mol Cell 19: 271-277
-
(2005)
Mol Cell
, vol.19
, pp. 271-277
-
-
Shahbazian, M.D.1
Zhang, K.2
Grunstein, M.3
-
175
-
-
13744259076
-
Characterization of the grappa gene, the Drosophila histone H3 lysine 79 methyltransferase
-
Shanower GA, Muller M, Blanton JL, Honti V, Gyurkovics H, Schedl P (2005)
-
(2005)
Genetics
, vol.169
, pp. 173-184
-
-
Shanower, G.A.1
Muller, M.2
Blanton, J.L.3
Honti, V.4
Gyurkovics, H.5
Schedl, P.6
-
176
-
-
33748698658
-
SAS-mediated acetylation of histone H4 Lys 16 is required for H2A. Z incorporation at subtelomeric regions in Saccharomyces cerevisiae
-
Shia WJ, Li B, Workman JL (2006) SAS-mediated acetylation of histone H4 Lys 16 is required for H2A. Z incorporation at subtelomeric regions in Saccharomyces cerevisiae. Genes Dev 20: 2507-2512
-
(2006)
Genes Dev
, vol.20
, pp. 2507-2512
-
-
Shia, W.J.1
Li, B.2
Workman, J.L.3
-
177
-
-
15744369742
-
Characterization of the yeast trimeric-SAS acetyltransferase complex
-
Shia WJ, Osada S, Florens L, Swanson SK, Washburn MP, Workman JL (2005) Characterization of the yeast trimeric-SAS acetyltransferase complex. J Biol Chem 280: 11987-11994
-
(2005)
J Biol Chem
, vol.280
, pp. 11987-11994
-
-
Shia, W.J.1
Osada, S.2
Florens, L.3
Swanson, S.K.4
Washburn, M.P.5
Workman, J.L.6
-
178
-
-
35848929051
-
Characterization of Drosophila telomeric retroelement TAHRE: Transcription, transpositions, and RNAi-based regulation of expression
-
Shpiz S, Kwon D, Uneva A, Kim M, Klenov M, Rozovsky Y, Georgiev P, Savitsky M, Kalmykova A (2007) Characterization of Drosophila telomeric retroelement TAHRE: transcription, transpositions, and RNAi-based regulation of expression. Mol Biol Evol 24: 2535-2545
-
(2007)
Mol Biol Evol
, vol.24
, pp. 2535-2545
-
-
Shpiz, S.1
Kwon, D.2
Uneva, A.3
Kim, M.4
Klenov, M.5
Rozovsky, Y.6
Georgiev, P.7
Savitsky, M.8
Kalmykova, A.9
-
179
-
-
4143123447
-
ATM is required for telomere maintenance and chromosome stability during Drosophila development
-
Silva E, Tiong S, Pedersen M, Homola E, Royou A, Fasulo B, Siriaco G, Campbell SD (2004) ATM is required for telomere maintenance and chromosome stability during Drosophila development. Curr Biol 14: 1341-1347
-
(2004)
Curr Biol
, vol.14
, pp. 1341-1347
-
-
Silva, E.1
Tiong, S.2
Pedersen, M.3
Homola, E.4
Royou, A.5
Fasulo, B.6
Siriaco, G.7
Campbell, S.D.8
-
180
-
-
40949130398
-
MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells
-
Sinkkonen L, Hugenschmidt T, Berninger P, Gaidatzis D, Mohn F, Artus-Revel CG, Zavolan M, Svoboda P, Filipowicz W (2008) MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells. Nat Struct Mol Biol 15: 259-267
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 259-267
-
-
Sinkkonen, L.1
Hugenschmidt, T.2
Berninger, P.3
Gaidatzis, D.4
Mohn, F.5
Artus-Revel, C.G.6
Zavolan, M.7
Svoboda, P.8
Filipowicz, W.9
-
181
-
-
39149115929
-
Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse
-
Stadtfeld M, Maherali N, Breault DT, Hochedlinger K (2008) Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. Cell Stem Cell 2: 230-240
-
(2008)
Cell Stem Cell
, vol.2
, pp. 230-240
-
-
Stadtfeld, M.1
Maherali, N.2
Breault, D.T.3
Hochedlinger, K.4
-
183
-
-
0031027431
-
SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast
-
Strahl-Bolsinger S, Hecht A, Luo K, Grunstein M (1997) SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast. Genes Dev 11: 83-93
-
(1997)
Genes Dev
, vol.11
, pp. 83-93
-
-
Strahl-Bolsinger, S.1
Hecht, A.2
Luo, K.3
Grunstein, M.4
-
184
-
-
33846703987
-
SHREC, an effector complex for heterochromatic transcriptional silencing
-
Sugiyama T, Cam HP, Sugiyama R, Noma K, Zofall M, Kobayashi R, Grewal SI (2007) SHREC, an effector complex for heterochromatic transcriptional silencing. Cell 128: 491-504
-
(2007)
Cell
, vol.128
, pp. 491-504
-
-
Sugiyama, T.1
Cam, H.P.2
Sugiyama, R.3
Noma, K.4
Zofall, M.5
Kobayashi, R.6
Grewal, S.I.7
-
185
-
-
0036842129
-
Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 Iysine16 and spreading of heterochromatin
-
Suka N, Luo K, Grunstein M (2002) Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 Iysine16 and spreading of heterochromatin. Nat Genet 32: 378-383
-
(2002)
Nat Genet
, vol.32
, pp. 378-383
-
-
Suka, N.1
Luo, K.2
Grunstein, M.3
-
186
-
-
0037019333
-
Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast
-
Sun ZW, Allis CD (2002) Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast. Nature 418: 104-108
-
(2002)
Nature
, vol.418
, pp. 104-108
-
-
Sun, Z.W.1
Allis, C.D.2
-
187
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S (2007) Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131: 861-872
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
188
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126: 663-676
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
189
-
-
0033598942
-
An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing
-
Tanny JC, Dowd GJ, Huang J, Hilz H, Moazed D (1999) An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing. Cell 99: 735-745
-
(1999)
Cell
, vol.99
, pp. 735-745
-
-
Tanny, J.C.1
Dowd, G.J.2
Huang, J.3
Hilz, H.4
Moazed, D.5
-
190
-
-
2042534735
-
Telomere length homeostasis is achieved via a switch between telomerase-extendible and -nonextendible states
-
Teixeira MT, Arneric M, Sperisen P, Lingner J (2004) Telomere length homeostasis is achieved via a switch between telomerase-extendible and -nonextendible states. Cell 117: 323-335
-
(2004)
Cell
, vol.117
, pp. 323-335
-
-
Teixeira, M.T.1
Arneric, M.2
Sperisen, P.3
Lingner, J.4
-
191
-
-
0033636907
-
Telomerase-independent lengthening of yeast telomeres occurs by an abrupt Rad50p-dependent, Rif-inhibited recombinational process
-
Teng SC, Chang J, McCowan B, Zakian VA (2000) Telomerase-independent lengthening of yeast telomeres occurs by an abrupt Rad50p-dependent, Rif-inhibited recombinational process. Mol Cell 6: 947-952
-
(2000)
Mol Cell
, vol.6
, pp. 947-952
-
-
Teng, S.C.1
Chang, J.2
McCowan, B.3
Zakian, V.A.4
-
192
-
-
0037148368
-
Transcriptional silencing at Saccharomyces telomeres: Implications for other organisms
-
Tham WH, Zakian VA (2002) Transcriptional silencing at Saccharomyces telomeres: implications for other organisms. Oncogens 21: 512-521
-
(2002)
Oncogens
, vol.21
, pp. 512-521
-
-
Tham, W.H.1
Zakian, V.A.2
-
193
-
-
0026652376
-
The clr1 locus regulates the expression of the cryptic mating-type loci of fission yeast
-
Thon G, Klar AJ (1992) The clr1 locus regulates the expression of the cryptic mating-type loci of fission yeast. Genetics 131: 287-296
-
(1992)
Genetics
, vol.131
, pp. 287-296
-
-
Thon, G.1
Klar, A.J.2
-
194
-
-
33845417885
-
The cancer epigenome - components and functional correlates
-
Ting AH, McGarvey KM, Baylin SB (2006) The cancer epigenome - components and functional correlates. Genes Dev 20: 3215-3231
-
(2006)
Genes Dev
, vol.20
, pp. 3215-3231
-
-
Ting, A.H.1
McGarvey, K.M.2
Baylin, S.B.3
-
195
-
-
55449122193
-
Telomerase reverse tran-scriptase delays aging in cancer-resistant mice
-
Tomas-Loba A, Flores I, Fernandez-Marcos PJ, Cayuela ML, Maraver A, Tejera A, Borras C, Matheu A, Klatt P, Flores JM, Vina J, Serrano M, Blasco MA (2008) Telomerase reverse tran-scriptase delays aging in cancer-resistant mice. Cell 135: 609-622
-
(2008)
Cell
, vol.135
, pp. 609-622
-
-
Tomas-Loba, A.1
Flores, I.2
Fernandez-Marcos, P.J.3
Cayuela, M.L.4
Maraver, A.5
Tejera, A.6
Borras, C.7
Matheu, A.8
Klatt, P.9
Flores, J.M.10
Vina, J.11
Serrano, M.12
Blasco, M.A.13
-
196
-
-
58049204228
-
Fission yeast Ccq1 is telomerase recruiter and local checkpoint controller
-
Tomita K, Cooper JP (2008) Fission yeast Ccq1 is telomerase recruiter and local checkpoint controller. Genes Dev 22: 3461-3474
-
(2008)
Genes Dev
, vol.22
, pp. 3461-3474
-
-
Tomita, K.1
Cooper, J.P.2
-
198
-
-
32544452237
-
Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins
-
Tryndyak VP, Kovalchuk O, Pogribny IP (2006) Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins. Cancer Biol Ther 5: 65-70
-
(2006)
Cancer Biol Ther
, vol.5
, pp. 65-70
-
-
Tryndyak, V.P.1
Kovalchuk, O.2
Pogribny, I.P.3
-
199
-
-
34250614359
-
Adult-onset pulmonary fibrosis caused by mutations in telomerase
-
Tsakiri KD, Cronkhite JT, Kuan PJ, Xing C, Raghu G, Weissler JC, Rosenblatt RL, Shay JW, Garcia CK (2007) Adult-onset pulmonary fibrosis caused by mutations in telomerase. Proc Natl Acad Sci USA 104: 7552-7557
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7552-7557
-
-
Tsakiri, K.D.1
Cronkhite, J.T.2
Kuan, P.J.3
Xing, C.4
Raghu, G.5
Weissler, J.C.6
Rosenblatt, R.L.7
Shay, J.W.8
Garcia, C.K.9
-
200
-
-
23844517498
-
Obesity, cigarette smoking, and telomere length in women
-
Valdes AM, Andrew T, Gardner JP, Kimura M, Oelsner E, Cherkas LF, Aviv A, Spector TD (2005) Obesity, cigarette smoking, and telomere length in women. Lancet 366: 662-664
-
(2005)
Lancet
, vol.366
, pp. 662-664
-
-
Valdes, A.M.1
Andrew, T.2
Gardner, J.P.3
Kimura, M.4
Oelsner, E.5
Cherkas, L.F.6
Aviv, A.7
Spector, T.D.8
-
201
-
-
0037077178
-
Dot1p modulates silencing in yeast by methylation of the nucleosome core
-
van Leeuwen F, Gafken PR, Gottschling DE (2002) Dot1p modulates silencing in yeast by methylation of the nucleosome core. Cell 109: 745-756
-
(2002)
Cell
, vol.109
, pp. 745-756
-
-
van Leeuwen, F.1
Gafken, P.R.2
Gottschling, D.E.3
-
202
-
-
0036897852
-
Genome-wide histone modifications: Gaining specificity by preventing promiscuity
-
van Leeuwen F, Gottschling DE (2002) Genome-wide histone modifications: gaining specificity by preventing promiscuity. Curr Opin Cell Biol 14: 756-762
-
(2002)
Curr Opin Cell Biol
, vol.14
, pp. 756-762
-
-
van Leeuwen, F.1
Gottschling, D.E.2
-
203
-
-
0345257778
-
Hypomethylation of D4Z4 in 4q-linked and non-4q-linked facioscapulohumeral muscular dystrophy
-
van Overveld PG, Lemmers RJ, Sandkuijl LA, Enthoven L, Winokur ST, Bakels F, Padberg GW, van Ommen GJ, Frants RR, van der Maarel SM (2003) Hypomethylation of D4Z4 in 4q-linked and non-4q-linked facioscapulohumeral muscular dystrophy. Nat Genet 35: 315-317
-
(2003)
Nat Genet
, vol.35
, pp. 315-317
-
-
van Overveld, P.G.1
Lemmers, R.J.2
Sandkuijl, L.A.3
Enthoven, L.4
Winokur, S.T.5
Bakels, F.6
Padberg, G.W.7
van Ommen, G.J.8
Frants, R.R.9
van der Maarel, S.M.10
-
204
-
-
56649115881
-
Epigenetic regulation of telomeres in human cancer
-
Vera E, Canela A, Fraga MF, Esteller M, Blasco MA (2008) Epigenetic regulation of telomeres in human cancer. Oncogene 27: 6817-6833
-
(2008)
Oncogene
, vol.27
, pp. 6817-6833
-
-
Vera, E.1
Canela, A.2
Fraga, M.F.3
Esteller, M.4
Blasco, M.A.5
-
205
-
-
0942279635
-
RNAi-mediated targeting of heterochromatin by the RITS complex
-
Verdel A, Jia S, Gerber S, Sugiyama T, Gygi S, Grewal SI, Moazed D (2004) RNAi-mediated targeting of heterochromatin by the RITS complex. Science 303: 672-676
-
(2004)
Science
, vol.303
, pp. 672-676
-
-
Verdel, A.1
Jia, S.2
Gerber, S.3
Sugiyama, T.4
Gygi, S.5
Grewal, S.I.6
Moazed, D.7
-
206
-
-
0034699380
-
Cloning of miceto six generations
-
Wakayama T, Shinkai Y, Tamashiro KL, Niida H, Blanchard DC, Blanchard RJ, Ogura A, Tanemura K, Tachibana M, Perry AC, Colgan DF, Mombaerts P, Yanagimachi R (2000) Cloning of miceto six generations. Nature 407: 318-319
-
(2000)
Nature
, vol.407
, pp. 318-319
-
-
Wakayama, T.1
Shinkai, Y.2
Tamashiro, K.L.3
Niida, H.4
Blanchard, D.C.5
Blanchard, R.J.6
Ogura, A.7
Tanemura, K.8
Tachibana, M.9
Perry, A.C.10
Colgan, D.F.11
Mombaerts, P.12
Yanagimachi, R.13
-
207
-
-
33846635931
-
Effects of telomere length in Drosophila melanogaster onlife span, fecundity, and fertility
-
BiessmannH
-
Walter MF, Biessmann MR, Benitez C, Torok T, Mason JM, BiessmannH (2007) Effects of telomere length in Drosophila melanogaster onlife span, fecundity, and fertility. Chromosoma 116: 41-51
-
(2007)
Chromosoma
, vol.116
, pp. 41-51
-
-
Walter, M.F.1
Biessmann, M.R.2
Benitez, C.3
Torok, T.4
Mason, J.M.5
-
208
-
-
0029592588
-
DNA organization and polymorphism of awild-type Drosophila telomere region
-
Walter MF, Jang C, Kasravi B, Donath J, Mechler BM, Mason JM, Biessmann H (1995) DNA organization and polymorphism of awild-type Drosophila telomere region. Chromosoma 104: 229-241
-
(1995)
Chromosoma
, vol.104
, pp. 229-241
-
-
Walter, M.F.1
Jang, C.2
Kasravi, B.3
Donath, J.4
Mechler, B.M.5
Mason, J.M.6
Biessmann, H.7
-
209
-
-
0029033861
-
The retinoblastoma protein and cell cyclecontrol
-
Weinberg RA (1995) The retinoblastoma protein and cell cyclecontrol. Cell 81: 323-330
-
(1995)
Cell
, vol.81
, pp. 323-330
-
-
Weinberg, R.A.1
-
211
-
-
0026563895
-
Saccharomycestelomeres assume a non-nucleosomal chromatin structure
-
Wright JH, Gottschling DE, Zakian VA (1992) Saccharomycestelomeres assume a non-nucleosomal chromatin structure. Genes Dev 6: 197-210
-
(1992)
Genes Dev
, vol.6
, pp. 197-210
-
-
Wright, J.H.1
Gottschling, D.E.2
Zakian, V.A.3
-
212
-
-
64249119735
-
Human telomere RNA and DNA form an intermolecular G-quadruplex
-
Xu Y, Kimura T, Komiyama M (2008) Human telomere RNA and DNA form an intermolecular G-quadruplex. Nucleic Acids Symp Ser (Oxf) 52: 169-170
-
(2008)
Nucleic Acids Symp Ser (Oxf)
, vol.52
, pp. 169-170
-
-
Xu, Y.1
Kimura, T.2
Komiyama, M.3
-
213
-
-
15944422499
-
Mutations in TERT, the gene for telomerase reverse transcriptase, in aplasticanemia
-
Yamaguchi H, Calado RT, Ly H, Kajigaya S, Baerlocher GM, Chanock SJ, Lansdorp PM, Young NS (2005) Mutations in TERT, the gene for telomerase reverse transcriptase, in aplasticanemia. N Engl J Med 352: 1413-1424
-
(2005)
N Engl J Med
, vol.352
, pp. 1413-1424
-
-
Yamaguchi, H.1
Calado, R.T.2
Ly, H.3
Kajigaya, S.4
Baerlocher, G.M.5
Chanock, S.J.6
Lansdorp, P.M.7
Young, N.S.8
-
214
-
-
50849099769
-
Hypomethylation of subtelomeric regions in ICF syndrome isassociated with abnormally short telomeres and enhancedtranscription from telomeric regions
-
Yehezkel S, Segev Y, Viegas-Pequignot E, Skorecki K, Selig S (2008) Hypomethylation of subtelomeric regions in ICF syndrome isassociated with abnormally short telomeres and enhancedtranscription from telomeric regions. Hum Mol Genet 17: 2776-2789
-
(2008)
Hum Mol Genet
, vol.17
, pp. 2776-2789
-
-
Yehezkel, S.1
Segev, Y.2
Viegas-Pequignot, E.3
Skorecki, K.4
Selig, S.5
-
215
-
-
36048937264
-
An epigenetic activation role of Piwi and aPiwi-associated piRNA in Drosophila melanogaster
-
Yin H, Lin H (2007) An epigenetic activation role of Piwi and aPiwi-associated piRNA in Drosophila melanogaster. Nature 450: 304-308
-
(2007)
Nature
, vol.450
, pp. 304-308
-
-
Yin, H.1
Lin, H.2
|