Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes

EMBO Journal

Volumn 20, Issue 11, 2001, Pages 2619-2630

  González Suárez, Eva ^a   Samper, Enrique ^a   Ramírez, Angel ^b   Flores, Juana M ^b   Martín Caballero, Juan ^a   Jorcano, José L ^b   Blasco, María A ^a  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Epithelial tumors; Gene therapy; mTERT; Skin carcinogenesis; Telomerase transgenic mouse

Indexed keywords

KERATIN; PHORBOL ESTER; TELOMERASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME REGULATION; GENE THERAPY; HISTOLOGY; KERATINOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SKIN CARCINOGENESIS; TELOMERE; TRANSGENIC MOUSE; WOUND HEALING;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; CATALYTIC DOMAIN; CATTLE; DNA-BINDING PROTEINS; FEMALE; GASTRIC MUCOSA; GENE THERAPY; GENES, P53; HYPERPLASIA; KERATINOCYTES; KERATINS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MOUTH MUCOSA; NEOPLASMS, EXPERIMENTAL; PAPILLOMA; PROTEIN SUBUNITS; RNA; SKIN; SKIN NEOPLASMS; STOMACH; TELOMERASE; TELOMERE; TETRADECANOYLPHORBOL ACETATE; VAGINA; WOUND HEALING;

EID: 0035355340     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.11.2619     Document Type: Article

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