-
1
-
-
0031972952
-
Telomere variation in Xenopus laevis
-
Bassham, S., Beam, A. & Shampay, J. 1998 Telomere variation in Xenopus laevis. Mol. Cell. Biol. 18, 269-275.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 269-275
-
-
Bassham, S.1
Beam, A.2
Shampay, J.3
-
3
-
-
0002974648
-
Telomerase
-
ed. R. F. Gesteland & J. F. Atkins, Cold Spring Harbor, NY: Cold Spring Harbor Laboratory
-
Blackburn, E. H. 1999 Telomerase. In The RNA world II (ed. R. F. Gesteland & J. F. Atkins), pp. 609-635. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
-
(1999)
The RNA World II
, pp. 609-635
-
-
Blackburn, E.H.1
-
4
-
-
0033788565
-
The end of the (DNA) line
-
Blackburn, E. H. 2000a The end of the (DNA) line. Nature Struct. Biol. 7, 847-850.
-
(2000)
Nature Struct. Biol.
, vol.7
, pp. 847-850
-
-
Blackburn, E.H.1
-
5
-
-
0034597794
-
Telomere states and cell fates
-
Blackburn, E. H. 2000b Telomere states and cell fates. Nature 408, 53-56.
-
(2000)
Nature
, vol.408
, pp. 53-56
-
-
Blackburn, E.H.1
-
6
-
-
0035929353
-
Switching and signaling at the telomere
-
Blackburn, E. H. 2001 Switching and signaling at the telomere. Cell 106, 661-673.
-
(2001)
Cell
, vol.106
, pp. 661-673
-
-
Blackburn, E.H.1
-
7
-
-
0021151105
-
The molecular structure of centomeres and telomeres
-
Blackburn, E. H. & Szostak, J. W. 1984 The molecular structure of centomeres and telomeres. A. Rev. Biochem. 53, 163-194.
-
(1984)
A. Rev. Biochem.
, vol.53
, pp. 163-194
-
-
Blackburn, E.H.1
Szostak, J.W.2
-
8
-
-
0034437351
-
Molecular manifestations and molecular determinants of telomere capping
-
Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
-
Blackburn, E. H., Chan, S., Chang, J., Fulton, T. B., Krauskopf, A., McEachern, M., Prescott, J., Roy, J., Smith, C. & Wang, H. 2000 Molecular manifestations and molecular determinants of telomere capping. In Cold Spring Harbor Symposia on Quantitative Biology: Biological responses to DNA damage. pp. 253-263. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
-
(2000)
Cold Spring Harbor Symposia on Quantitative Biology: Biological Responses to DNA Damage
, pp. 253-263
-
-
Blackburn, E.H.1
Chan, S.2
Chang, J.3
Fulton, T.B.4
Krauskopf, A.5
McEachern, M.6
Prescott, J.7
Roy, J.8
Smith, C.9
Wang, H.10
-
9
-
-
0036674425
-
Telomerase beyond telomeres
-
Blasco, M. A. 2002 Telomerase beyond telomeres. Nature Rev. Cancer 2, 627-633.
-
(2002)
Nature Rev. Cancer
, vol.2
, pp. 627-633
-
-
Blasco, M.A.1
-
10
-
-
0010045614
-
Extension of lifespan by introduction of telomerase into normal human cells
-
Bodnar, A. G., Ouellette, M., Frolkis, M., Holt, S. E., Chiu, C., Morin, M., Harley, C. B., Shay, J. W., Lichtsteiner, S. & Wright, W. E. 1998 Extension of lifespan by introduction of telomerase into normal human cells. Science 279, 349-352.
-
(1998)
Science
, vol.279
, pp. 349-352
-
-
Bodnar, A.G.1
Ouellette, M.2
Frolkis, M.3
Holt, S.E.4
Chiu, C.5
Morin, M.6
Harley, C.B.7
Shay, J.W.8
Lichtsteiner, S.9
Wright, W.E.10
-
11
-
-
0037308404
-
Association between telomere length in blood and mortality in people aged 60 years or older
-
Cawthon, R. M., Smith, K. R., O'Brien, E., Sivatchenko, A. & Kerber, R. A. 2003 Association between telomere length in blood and mortality in people aged 60 years or older. Lancet 361, 393-395.
-
(2003)
Lancet
, vol.361
, pp. 393-395
-
-
Cawthon, R.M.1
Smith, K.R.2
O'Brien, E.3
Sivatchenko, A.4
Kerber, R.A.5
-
12
-
-
0037228223
-
The Drosophila HOAP protein is required for telomere capping
-
Cenci, G., Siriaco, G., Raffa, G. D., Kellum, R. & Gatti, M. 2003 The Drosophila HOAP protein is required for telomere capping. Nature Cell Biol. 5, 82-84.
-
(2003)
Nature Cell Biol.
, vol.5
, pp. 82-84
-
-
Cenci, G.1
Siriaco, G.2
Raffa, G.D.3
Kellum, R.4
Gatti, M.5
-
13
-
-
0037148270
-
New ways not to make ends meet: Telomerase, DNA damage proteins and heterochromatin
-
Chan, S. W. & Blackburn, E. H. 2002 New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin. Oncogene 21, 553-563.
-
(2002)
Oncogene
, vol.21
, pp. 553-563
-
-
Chan, S.W.1
Blackburn, E.H.2
-
14
-
-
0037716757
-
Telomerase and the ATM homolog Tel1p protect telomeres from fusing to an induced double-stranded break
-
Chan, S. W. & Blackburn, E. H. 2003 Telomerase and the ATM homolog Tel1p protect telomeres from fusing to an induced double-stranded break. Mol. Cell 5, 1379-1387.
-
(2003)
Mol. Cell
, vol.5
, pp. 1379-1387
-
-
Chan, S.W.1
Blackburn, E.H.2
-
15
-
-
0035928740
-
Altering telomere structure allows telomerase to act in yeast lacking ATM kinases
-
Chan, S. W., Chang, J., Prescott, J. & Blackburn, E. H. 2001 Altering telomere structure allows telomerase to act in yeast lacking ATM kinases. Curr. Biol. 11, 1240-1250.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1240-1250
-
-
Chan, S.W.1
Chang, J.2
Prescott, J.3
Blackburn, E.H.4
-
16
-
-
0029155795
-
Telomerase in yeast
-
Cohn, M. & Blackburn, E. H. 1995 Telomerase in yeast. Science 269, 396-400.
-
(1995)
Science
, vol.269
, pp. 396-400
-
-
Cohn, M.1
Blackburn, E.H.2
-
17
-
-
0025222442
-
RAP1 protein interacts with yeast telomeres in vivo: Overproduction alters telomere structure and decreases chromosome stability
-
Conrad, M. N., Wright, J. H., Wolf, A. J. & Zakian, V. A. 1990 RAP1 protein interacts with yeast telomeres in vivo: overproduction alters telomere structure and decreases chromosome stability. Cell 63, 739-750.
-
(1990)
Cell
, vol.63
, pp. 739-750
-
-
Conrad, M.N.1
Wright, J.H.2
Wolf, A.J.3
Zakian, V.A.4
-
18
-
-
0031038170
-
Regulation of telomere length and function by a Mybdomain protein in fission yeast
-
Cooper, J. P., Nimmo, E. R., Allshire, R. C. & Cech, T. R. 1997 Regulation of telomere length and function by a Mybdomain protein in fission yeast. Nature 385, 744-747.
-
(1997)
Nature
, vol.385
, pp. 744-747
-
-
Cooper, J.P.1
Nimmo, E.R.2
Allshire, R.C.3
Cech, T.R.4
-
19
-
-
0026523228
-
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
-
Counter, C. M., Avilion, A. A., LeFeuvre, C. E., Stewart, N. G., Greider, C. W., Harley, C. B. & Bacchetti, S. 1992 Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J. 11, 1921-1929.
-
(1992)
EMBO J.
, vol.11
, pp. 1921-1929
-
-
Counter, C.M.1
Avilion, A.A.2
LeFeuvre, C.E.3
Stewart, N.G.4
Greider, C.W.5
Harley, C.B.6
Bacchetti, S.7
-
20
-
-
0035989348
-
Regulation of genome stability by TEL1 and MEC1, yeast homologs of the mammalian ATM and ATR genes
-
Craven, R. J., Greenwell, P. W., Dominska, M. & Petes, T. D. 2002 Regulation of genome stability by TEL1 and MEC1, yeast homologs of the mammalian ATM and ATR genes. Genetics 161, 493-507.
-
(2002)
Genetics
, vol.161
, pp. 493-507
-
-
Craven, R.J.1
Greenwell, P.W.2
Dominska, M.3
Petes, T.D.4
-
21
-
-
0033598944
-
Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta
-
Diede, S. J. & Gottschling, D. E. 1999 Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta. Cell 99, 723-733.
-
(1999)
Cell
, vol.99
, pp. 723-733
-
-
Diede, S.J.1
Gottschling, D.E.2
-
22
-
-
0036021349
-
A quantitative assay for telomere protection in Saccharomyces cerevisiae
-
DuBois, M. L., Haimberger, Z. W., McIntosh, M. W. & Gottschling., D. E. 2002 A quantitative assay for telomere protection in Saccharomyces cerevisiae. Genetics 161, 995-1013.
-
(2002)
Genetics
, vol.161
, pp. 995-1013
-
-
DuBois, M.L.1
Haimberger, Z.W.2
McIntosh, M.W.3
Gottschling, D.E.4
-
24
-
-
0037443874
-
Yeast telomerase is specialized for C/A-rich RNA templates
-
Forstemann, K., Zaug, A. J., Cech, T. R. & Lingner, J. 2003 Yeast telomerase is specialized for C/A-rich RNA templates. Nucleic Acids Res. 31, 1646-1655.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 1646-1655
-
-
Forstemann, K.1
Zaug, A.J.2
Cech, T.R.3
Lingner, J.4
-
25
-
-
13144305133
-
The rate of telomere sequence loss in human leukocytes varies with age
-
Frenck Jr, R. W., Blackburn, E. H. & Shannon, K. M. 1998 The rate of telomere sequence loss in human leukocytes varies with age. Proc. Natl Acad. Sci. USA 95, 5607-5610.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 5607-5610
-
-
Frenck Jr., R.W.1
Blackburn, E.H.2
Shannon, K.M.3
-
26
-
-
0031842099
-
Identification of Kluyveromyces lactis telomerase: Discontinuous synthesis along the 30-nucleotide-long templating domain
-
Fulton, T. B. & Blackburn, E. H. 1998 Identification of Kluyveromyces lactis telomerase: discontinuous synthesis along the 30-nucleotide-long templating domain. Mol. Cell. Biol. 18, 4961-4970.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 4961-4970
-
-
Fulton, T.B.1
Blackburn, E.H.2
-
27
-
-
0029655261
-
Specific RNA residue interactions required for enzymatic functions of Tetrahymena telomerase
-
Gilley, D. & Blackburn, E. H. 1996 Specific RNA residue interactions required for enzymatic functions of Tetrahymena telomerase. Mol. Cell. Biol. 16, 66-75.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 66-75
-
-
Gilley, D.1
Blackburn, E.H.2
-
28
-
-
0029144984
-
Altering specific telomerase RNA template residues affects active site function
-
Gilley, D., Lee, M. S. & Blackburn, E. H. 1995 Altering specific telomerase RNA template residues affects active site function. Genes Dev. 9, 2214-2226.
-
(1995)
Genes Dev.
, vol.9
, pp. 2214-2226
-
-
Gilley, D.1
Lee, M.S.2
Blackburn, E.H.3
-
29
-
-
0022402513
-
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
-
Greider, C. W. & Blackburn, E. H. 1985 Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 43, 405-413.
-
(1985)
Cell
, vol.43
, pp. 405-413
-
-
Greider, C.W.1
Blackburn, E.H.2
-
30
-
-
0023663881
-
The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two distinct primer specificity components
-
Greider, C. W. & Blackburn, E. H. 1987 The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two distinct primer specificity components. Cell 51, 887-898.
-
(1987)
Cell
, vol.51
, pp. 887-898
-
-
Greider, C.W.1
Blackburn, E.H.2
-
31
-
-
0024978857
-
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
-
Greider, C. W. & Blackburn, E. H. 1989 A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis. Nature 337, 331-337.
-
(1989)
Nature
, vol.337
, pp. 331-337
-
-
Greider, C.W.1
Blackburn, E.H.2
-
32
-
-
0025143252
-
Telomere reduction in human colorectal carcinoma and with ageing
-
Hastie, N. D., Dempster, M., Dunlop, M. G., Thompson, A. M., Green, D. K. & Allshire, R. C. 1990 Telomere reduction in human colorectal carcinoma and with ageing. Nature 346, 866-868.
-
(1990)
Nature
, vol.346
, pp. 866-868
-
-
Hastie, N.D.1
Dempster, M.2
Dunlop, M.G.3
Thompson, A.M.4
Green, D.K.5
Allshire, R.C.6
-
33
-
-
0036717650
-
Telomeres in T and B cells
-
Hodes, R. J., Hathcock, K. S. & Weng, N. P. 2002 Telomeres in T and B cells. Nature Rev. Immunol. 2, 699-706.
-
(2002)
Nature Rev. Immunol.
, vol.2
, pp. 699-706
-
-
Hodes, R.J.1
Hathcock, K.S.2
Weng, N.P.3
-
34
-
-
0037192462
-
Senescence induced by altered telomere state, not telomere loss
-
Karlseder, J., Smogorzewska, A. & de Lange, T. 2002 Senescence induced by altered telomere state, not telomere loss. Science 295, 2446-2449.
-
(2002)
Science
, vol.295
, pp. 2446-2449
-
-
Karlseder, J.1
Smogorzewska, A.2
De Lange, T.3
-
35
-
-
0035189448
-
ATM: A key determinant of multiple cellular responses to irradiation
-
Kastan, M. B., Lim, D. S., Kim, S. T. & Yang, D. 2001 ATM: a key determinant of multiple cellular responses to irradiation. Acta Oncol. 40, 686-688.
-
(2001)
Acta Oncol.
, vol.40
, pp. 686-688
-
-
Kastan, M.B.1
Lim, D.S.2
Kim, S.T.3
Yang, D.4
-
36
-
-
0034933876
-
A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation
-
Kim, M. M., Rivera, M. A., Botchkina, I. L., Shalaby, R., Thor, A. D. & Blackburn, E. H. 2001 A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation. Proc. Nad Acad. Sci. USA 98, 7982-7987.
-
(2001)
Proc. Nad Acad. Sci. USA
, vol.98
, pp. 7982-7987
-
-
Kim, M.M.1
Rivera, M.A.2
Botchkina, I.L.3
Shalaby, R.4
Thor, A.D.5
Blackburn, E.H.6
-
37
-
-
0041562482
-
Catalytically normal human telomerase mutants with allele-specific biological properties
-
Kim, M. M., Xu, L. & Blackburn, E. H. 2003 Catalytically normal human telomerase mutants with allele-specific biological properties. Exp. Cell Res. 288, 277-287.
-
(2003)
Exp. Cell Res.
, vol.288
, pp. 277-287
-
-
Kim, M.M.1
Xu, L.2
Blackburn, E.H.3
-
38
-
-
0032727616
-
TIN2, a new regulator of telomere length in human cells
-
Kim, S. H., Kaminker, P. & Campisi, J. 1999 TIN2, a new regulator of telomere length in human cells. Nature Genet. 23, 405-412.
-
(1999)
Nature Genet.
, vol.23
, pp. 405-412
-
-
Kim, S.H.1
Kaminker, P.2
Campisi, J.3
-
39
-
-
0034614357
-
Molecular 'vitalism'
-
Kirschner, M., Gerhart, J. & Mitchison, T. 2000 Molecular 'vitalism'. Cell 100, 79-88.
-
(2000)
Cell
, vol.100
, pp. 79-88
-
-
Kirschner, M.1
Gerhart, J.2
Mitchison, T.3
-
40
-
-
0029743764
-
Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats
-
Krauskopf, A. & Blackburn, E. H. 1996 Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats. Nature 383, 354-357.
-
(1996)
Nature
, vol.383
, pp. 354-357
-
-
Krauskopf, A.1
Blackburn, E.H.2
-
41
-
-
0032514694
-
Rap1 protein regulates telomere turnover in yeast
-
Krauskopf, A. & Blackburn, E. H. 1998 Rap1 protein regulates telomere turnover in yeast. Proc. Natl Acad. Sci. USA 95, 12 486-12 491.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 12486-12491
-
-
Krauskopf, A.1
Blackburn, E.H.2
-
42
-
-
0033940731
-
The dynamics of yeast telomeres and silencing proteins through the cell cycle
-
Laroche, T., Martin, S. G., Tsai-Pflugfelder, M. & Gasser, S. M. 2000 The dynamics of yeast telomeres and silencing proteins through the cell cycle. J. Struct. Biol. 129, 159-174.
-
(2000)
J. Struct. Biol.
, vol.129
, pp. 159-174
-
-
Laroche, T.1
Martin, S.G.2
Tsai-Pflugfelder, M.3
Gasser, S.M.4
-
43
-
-
0027486026
-
Sequence-specific DNA primer effects on telomerase polymerization activity
-
Lee, M. S. & Blackburn, E. H. 1993 Sequence-specific DNA primer effects on telomerase polymerization activity. Mol. Cell. Biol. 13, 6586-6599.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 6586-6599
-
-
Lee, M.S.1
Blackburn, E.H.2
-
44
-
-
1642423569
-
Mutant telomere sequences lead to impaired chromosome separation and a unique checkpoint response
-
Submitted
-
Lin, J., Smith, D. L. & Blackburn, E. H. 2004 Mutant telomere sequences lead to impaired chromosome separation and a unique checkpoint response. Mol. Biol. Cell. (Submitted.)
-
(2004)
Mol. Biol. Cell.
-
-
Lin, J.1
Smith, D.L.2
Blackburn, E.H.3
-
45
-
-
0030938901
-
Reverse transcriptase motifs in the catalytic subunit of telomerase
-
Lingner, J., Hughes, T. R., Shevchenko, A., Mann, M., Lundblad, V. & Cech, T. R. 1997 Reverse transcriptase motifs in the catalytic subunit of telomerase. Science 276, 561-567.
-
(1997)
Science
, vol.276
, pp. 561-567
-
-
Lingner, J.1
Hughes, T.R.2
Shevchenko, A.3
Mann, M.4
Lundblad, V.5
Cech, T.R.6
-
46
-
-
0038305629
-
A role for a novel 'trans-pseudoknot' RNA-RNA interaction in the functional dimerization of human telomerase
-
Ly, H., Xu, L., Rivera, M. A., Parslow, T. G. & Blackburn, E. H. 2003a A role for a novel 'trans-pseudoknot' RNA-RNA interaction in the functional dimerization of human telomerase. Genes Dev. 17, 1078-1083.
-
(2003)
Genes Dev.
, vol.17
, pp. 1078-1083
-
-
Ly, H.1
Xu, L.2
Rivera, M.A.3
Parslow, T.G.4
Blackburn, E.H.5
-
47
-
-
0141557781
-
Comprehensive structure-function analysis of the core domain of human telomerase RNA
-
Ly, H., Blackburn, E. H. & Parslow, T. G. 2003b Comprehensive structure-function analysis of the core domain of human telomerase RNA. Mol. Cell. Biol. 23, 6849-6856.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 6849-6856
-
-
Ly, H.1
Blackburn, E.H.2
Parslow, T.G.3
-
48
-
-
0002641054
-
The fusion of broken ends of sister half-chromatids following chromatid breakage at meiotic anaphase
-
McClintock, B. 1938 The fusion of broken ends of sister half-chromatids following chromatid breakage at meiotic anaphase. Res. Bull. Mo. Agric. Esp. Stn. 290, 1-48.
-
(1938)
Res. Bull. Mo. Agric. Esp. Stn.
, vol.290
, pp. 1-48
-
-
McClintock, B.1
-
49
-
-
0001294157
-
The stability of broken ends of chromosomes in Zea mays
-
McClintock, B. 1941 The stability of broken ends of chromosomes in Zea mays. Genetics 26, 234-282.
-
(1941)
Genetics
, vol.26
, pp. 234-282
-
-
McClintock, B.1
-
50
-
-
0000980730
-
The fusion of broken ends of chromosomes following nuclear fusion
-
McClintock, B. 1942 The fusion of broken ends of chromosomes following nuclear fusion. Proc. Natl Acad. Sci. USA 28, 458-463.
-
(1942)
Proc. Natl. Acad. Sci. USA
, vol.28
, pp. 458-463
-
-
McClintock, B.1
-
51
-
-
0030008072
-
A single telomerase RNA is sufficient for the synthesis of variable telomeric DNA repeats in ciliates of the genus Paramecium
-
McCormick-Graham, M. & Romero, D. P. 1996 A single telomerase RNA is sufficient for the synthesis of variable telomeric DNA repeats in ciliates of the genus Paramecium. Mol. Cell. Biol. 16, 1871-1879.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1871-1879
-
-
McCormick-Graham, M.1
Romero, D.P.2
-
52
-
-
0029102354
-
Runaway telomere elongation caused by telomerase RNA gene mutations
-
McEachern, M. J. & Blackburn, E. H. 1995 Runaway telomere elongation caused by telomerase RNA gene mutations. Nature 376, 403-409.
-
(1995)
Nature
, vol.376
, pp. 403-409
-
-
McEachern, M.J.1
Blackburn, E.H.2
-
53
-
-
0034500453
-
Telomeres and their control
-
McEachern, M. J., Krauskopf, A. & Blackburn, E. H. 2000 Telomeres and their control. A. Rev. Genet. 34, 331-358.
-
(2000)
A. Rev. Genet.
, vol.34
, pp. 331-358
-
-
McEachern, M.J.1
Krauskopf, A.2
Blackburn, E.H.3
-
54
-
-
0031036351
-
A protein-counting mechanism for telomere length regulation in yeast
-
Marcand, S., Gilson, E. & Shore, D. 1997 A protein-counting mechanism for telomere length regulation in yeast. Science 275, 986-990.
-
(1997)
Science
, vol.275
, pp. 986-990
-
-
Marcand, S.1
Gilson, E.2
Shore, D.3
-
55
-
-
0034175814
-
Cell cycle restriction of telomere elongation
-
Marcand, S., Brevet, V., Mann, C. & Gilson, E. 2000 Cell cycle restriction of telomere elongation. Curr. Biol. 10, 487-490.
-
(2000)
Curr. Biol.
, vol.10
, pp. 487-490
-
-
Marcand, S.1
Brevet, V.2
Mann, C.3
Gilson, E.4
-
56
-
-
0037112522
-
Telomere shortening is an early somatic DNA alteration in human prostate tumorigenesis
-
Meeker, A. K., Hicks, J. L., Platz, E. A., March, G. E., Bennett, C. J., Delannoy, M. J. & De Marzo, A. M. 2002 Telomere shortening is an early somatic DNA alteration in human prostate tumorigenesis. Cancer Res. 62, 6405-6409.
-
(2002)
Cancer Res.
, vol.62
, pp. 6405-6409
-
-
Meeker, A.K.1
Hicks, J.L.2
Platz, E.A.3
March, G.E.4
Bennett, C.J.5
Delannoy, M.J.6
De Marzo, A.M.7
-
57
-
-
0037023303
-
Conserved structure for single-stranded telomeric DNA recognition
-
Mitton-Fry, R. M., Anderson, E. M., Hughes, T. R., Lundblad, V. & Wuttke, D. S. 2002 Conserved structure for single-stranded telomeric DNA recognition. Science 296, 145-147.
-
(2002)
Science
, vol.296
, pp. 145-147
-
-
Mitton-Fry, R.M.1
Anderson, E.M.2
Hughes, T.R.3
Lundblad, V.4
Wuttke, D.S.5
-
58
-
-
0036516868
-
Technical advances and pitfalls on the way to human cloning
-
Mollard, R., Denham, M. & Trounson, A. 2002 Technical advances and pitfalls on the way to human cloning. Differentiation 70, 1-9.
-
(2002)
Differentiation
, vol.70
, pp. 1-9
-
-
Mollard, R.1
Denham, M.2
Trounson, A.3
-
59
-
-
0000049842
-
The remaking of chromosomes
-
Muller, H. J. 1938 The remaking of chromosomes. Collecting Net. 13, 182-198.
-
(1938)
Collecting Net.
, vol.13
, pp. 182-198
-
-
Muller, H.J.1
-
60
-
-
0000757672
-
Concerning the healing of chromosome ends produced by breakage in Drosophila melanogaster
-
Muller, H. J. & Herskowitz, I. H. 1954 Concerning the healing of chromosome ends produced by breakage in Drosophila melanogaster. Am. Nat. 88, 177-208.
-
(1954)
Am. Nat.
, vol.88
, pp. 177-208
-
-
Muller, H.J.1
Herskowitz, I.H.2
-
61
-
-
0035963338
-
Multiple pathways cooperate in the suppression of genome instability in S. cerevisiae
-
Myung, K., Chen, C. & Kolodner, R. D. 2001 Multiple pathways cooperate in the suppression of genome instability in S. cerevisiae. Nature 411, 1073-1076.
-
(2001)
Nature
, vol.411
, pp. 1073-1076
-
-
Myung, K.1
Chen, C.2
Kolodner, R.D.3
-
62
-
-
0032489351
-
Reversing time: Origin of telomerase
-
Nakamura, T. M. & Cech, T. R. 1998 Reversing time: origin of telomerase. Cell 92, 587-590.
-
(1998)
Cell
, vol.92
, pp. 587-590
-
-
Nakamura, T.M.1
Cech, T.R.2
-
63
-
-
0030819894
-
Telomerase catalytic subunit homologs from fission yeast and human
-
Nakamura, T. M., Morin, G. B., Chapman, K. B., Weinrich, S. L., Andrews, W. H., Lingner, J., Harley, C. B. & Cech, T. R. 1997 Telomerase catalytic subunit homologs from fission yeast and human. Science 277, 955-959.
-
(1997)
Science
, vol.277
, pp. 955-959
-
-
Nakamura, T.M.1
Morin, G.B.2
Chapman, K.B.3
Weinrich, S.L.4
Andrews, W.H.5
Lingner, J.6
Harley, C.B.7
Cech, T.R.8
-
64
-
-
0015844590
-
A theory of marginotomy
-
Olovnikov, A. M. 1973 A theory of marginotomy. J. Theor. Biol. 41, 181-190.
-
(1973)
J. Theor. Biol.
, vol.41
, pp. 181-190
-
-
Olovnikov, A.M.1
-
65
-
-
0013687583
-
Drosophila telomeres: Another way to end it all
-
ed. E. H. Blackburn & C. W. Greider, Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
-
Pardue, M. L. 1995 Drosophila telomeres: another way to end it all. In Telomeres (ed. E. H. Blackburn & C. W. Greider), pp. 339-370. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
-
(1995)
Telomeres
, pp. 339-370
-
-
Pardue, M.L.1
-
66
-
-
0030781067
-
Functionally interacting telomerase RNAs in the yeast telomerase complex
-
Prescott, J. & Blackburn, E. H. 1997a Functionally interacting telomerase RNAs in the yeast telomerase complex. Genes Dev. 11, 2790-2800.
-
(1997)
Genes Dev.
, vol.11
, pp. 2790-2800
-
-
Prescott, J.1
Blackburn, E.H.2
-
67
-
-
0031029377
-
Telomerase RNA mutations in Saccharomyces cerevisiae alter telomerase action and reveal nonprocessivity in vivo and in vitro
-
Prescott, J. & Blackburn, E. H. 1997b Telomerase RNA mutations in Saccharomyces cerevisiae alter telomerase action and reveal nonprocessivity in vivo and in vitro. Genes Dev. 11, 528-540.
-
(1997)
Genes Dev.
, vol.11
, pp. 528-540
-
-
Prescott, J.1
Blackburn, E.H.2
-
68
-
-
0034068910
-
Telomerase RNA template mutations reveal sequence-specific requirements for the activation and repression of telomerase action at telomeres
-
Prescott, J. C. & Blackburn, E. H. 2000 Telomerase RNA template mutations reveal sequence-specific requirements for the activation and repression of telomerase action at telomeres. Mol. Cell. Biol. 20, 2941-2948.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 2941-2948
-
-
Prescott, J.C.1
Blackburn, E.H.2
-
69
-
-
1642478139
-
Processive utilization of the human telomerase template: Lack of a requirement for template switching
-
Submitted
-
Rivera, M. A. & Blackburn, E. H. 2004 Processive utilization of the human telomerase template: lack of a requirement for template switching. Mol. Cell. Biol. (Submitted.)
-
(2004)
Mol. Cell. Biol.
-
-
Rivera, M.A.1
Blackburn, E.H.2
-
70
-
-
0037221969
-
Homeostasis of telomere length rather than telomere shortening after allogeneic peripheral blood stem cell transplantation
-
Roelofs, H., de Pauw, E. S., Zwinderman, A. H., Opdam, S. M., Willemze, R., Tanke, H. J. & Fibbe, W. E. 2003 Homeostasis of telomere length rather than telomere shortening after allogeneic peripheral blood stem cell transplantation. Blood 101, 358-362.
-
(2003)
Blood
, vol.101
, pp. 358-362
-
-
Roelofs, H.1
De Pauw, E.S.2
Zwinderman, A.H.3
Opdam, S.M.4
Willemze, R.5
Tanke, H.J.6
Fibbe, W.E.7
-
71
-
-
0032532428
-
Specific telomerase RNA residues distant from the template are essential for telomerase function
-
Roy, J., Fulton, T. B. & Blackburn, E. H. 1998 Specific telomerase RNA residues distant from the template are essential for telomerase function. Genes Dev. 12, 3286-3300.
-
(1998)
Genes Dev.
, vol.12
, pp. 3286-3300
-
-
Roy, J.1
Fulton, T.B.2
Blackburn, E.H.3
-
72
-
-
0025021235
-
Functional evidence for an RNA template in telomerase
-
Shippen-Lentz, D. & Blackburn, E. H. 1990 Functional evidence for an RNA template in telomerase. Science 247, 546-552.
-
(1990)
Science
, vol.247
, pp. 546-552
-
-
Shippen-Lentz, D.1
Blackburn, E.H.2
-
73
-
-
0027944347
-
TLC1: Template RNA component of Saccharomyces cerevisiae telomerase
-
Singer, M. S. & Gottschling, D. E. 1994 TLC1: template RNA component of Saccharomyces cerevisiae telomerase. Science 266, 404-409.
-
(1994)
Science
, vol.266
, pp. 404-409
-
-
Singer, M.S.1
Gottschling, D.E.2
-
74
-
-
0345643517
-
Uncapping and deregulation of telomeres lead to detrimental cellular consequences in yeast
-
Smith, C. D. & Blackburn, E. H. 1999 Uncapping and deregulation of telomeres lead to detrimental cellular consequences in yeast. J. Cell Biol. 145, 203-214.
-
(1999)
J. Cell Biol.
, vol.145
, pp. 203-214
-
-
Smith, C.D.1
Blackburn, E.H.2
-
75
-
-
0037326054
-
Telomeric protein distributions and remodeling through the cell cycle in S. cerevisiae
-
Smith, C. D., Smith, D. L., DeRisi, J. L. & Blackburn, E. H. 2002 Telomeric protein distributions and remodeling through the cell cycle in S. cerevisiae. Mol. Biol. Cell 14, 556-570.
-
(2002)
Mol. Biol. Cell
, vol.14
, pp. 556-570
-
-
Smith, C.D.1
Smith, D.L.2
DeRisi, J.L.3
Blackburn, E.H.4
-
76
-
-
0037047643
-
Est1p as a cell cycle-regulated activator of telomere-bound telomerase
-
Taggart, A. K., Teng, S. C. & Zakian, V. A. 2002 Est1p as a cell cycle-regulated activator of telomere-bound telomerase. Science 297, 1023-1026.
-
(2002)
Science
, vol.297
, pp. 1023-1026
-
-
Taggart, A.K.1
Teng, S.C.2
Zakian, V.A.3
-
77
-
-
0035806977
-
The role of the Mre11-Rad50-Xrs2 complex in telomerase-mediated lengthening of Saccharomyces cerevisiae telomeres
-
Tsukamoto, Y., Taggart, A. K. & Zakian, V. A. 2001 The role of the Mre11-Rad50-Xrs2 complex in telomerase-mediated lengthening of Saccharomyces cerevisiae telomeres. Curr. Biol. 11, 1328-1335.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1328-1335
-
-
Tsukamoto, Y.1
Taggart, A.K.2
Zakian, V.A.3
-
78
-
-
0037829618
-
A novel pseudoknot element is essential for the action of a yeast telomerase
-
Tzfati, Y., Knight, Z., Roy, J. & Blackburn, E. H. 2003 A novel pseudoknot element is essential for the action of a yeast telomerase. Genes Dev. 17, 1779-1788.
-
(2003)
Genes Dev.
, vol.17
, pp. 1779-1788
-
-
Tzfati, Y.1
Knight, Z.2
Roy, J.3
Blackburn, E.H.4
-
79
-
-
0031027618
-
Control of telomere length by the human telomeric protein TRF1
-
Van Steensel, B. & de Lange, T. 1997 Control of telomere length by the human telomeric protein TRF1. Nature 385, 740-743.
-
(1997)
Nature
, vol.385
, pp. 740-743
-
-
Van Steensel, B.1
De Lange, T.2
-
80
-
-
0036629255
-
Oxidative stress shortens telomeres
-
Von Zglinicki, T. 2002 Oxidative stress shortens telomeres. Trends Biochem. Sci. 27, 339-344.
-
(2002)
Trends Biochem. Sci.
, vol.27
, pp. 339-344
-
-
Von Zglinicki, T.1
-
81
-
-
0035960043
-
The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita
-
Vulliamy, T., Marrone, A., Goldman, F., Dearlove, A., Bessler, M., Mason, P. J. & Dokal, I. 2001 The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita. Nature 413, 432-435.
-
(2001)
Nature
, vol.413
, pp. 432-435
-
-
Vulliamy, T.1
Marrone, A.2
Goldman, F.3
Dearlove, A.4
Bessler, M.5
Mason, P.J.6
Dokal, I.7
-
83
-
-
0034659801
-
Three telomerases with completely non-telomeric template replacements are catalytically active
-
Ware, T. L., Wang, H. & Blackburn, E. H. 2000 Three telomerases with completely non-telomeric template replacements are catalytically active. EMBO J. 19, 3119-3131.
-
(2000)
EMBO J.
, vol.19
, pp. 3119-3131
-
-
Ware, T.L.1
Wang, H.2
Blackburn, E.H.3
-
84
-
-
0029953557
-
Evidence for a new step in telomere maintenance
-
Wellinger, R. J., Ethier, K., Labrecque, P. & Zakian, V. A. 1996 Evidence for a new step in telomere maintenance. Cell 85, 423-433.
-
(1996)
Cell
, vol.85
, pp. 423-433
-
-
Wellinger, R.J.1
Ethier, K.2
Labrecque, P.3
Zakian, V.A.4
-
85
-
-
0037421896
-
Telomere dysfunction and ATM deficiency compromises organ homeostasis and accelerates ageing
-
Wong, K. K., Maser, R. S., Bachoo, R. M., Menon, J., Carrasco, D. R., Gu, Y., Alt, F. W. & DePinho, R. A. 2003 Telomere dysfunction and ATM deficiency compromises organ homeostasis and accelerates ageing. Nature 421, 643-648.
-
(2003)
Nature
, vol.421
, pp. 643-648
-
-
Wong, K.K.1
Maser, R.S.2
Bachoo, R.M.3
Menon, J.4
Carrasco, D.R.5
Gu, Y.6
Alt, F.W.7
DePinho, R.A.8
-
86
-
-
0030995534
-
A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae
-
Wotton, D. & Shore, D. 1997 A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae. Genes Dev. 11, 748-760.
-
(1997)
Genes Dev.
, vol.11
, pp. 748-760
-
-
Wotton, D.1
Shore, D.2
-
87
-
-
0025279059
-
In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs
-
Yu, G. L., Bradley, J. D., Attardi, L. D. & Blackburn, E. H. 1990 In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs. Nature 344, 126-132.
-
(1990)
Nature
, vol.344
, pp. 126-132
-
-
Yu, G.L.1
Bradley, J.D.2
Attardi, L.D.3
Blackburn, E.H.4
-
88
-
-
0033616762
-
Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening
-
Zhu, J., Wang, H., Bishop, J. M. & Blackburn, E. H. 1999 Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening. Proc. Natl Acad. Sci. USA 96, 3723-3728.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 3723-3728
-
-
Zhu, J.1
Wang, H.2
Bishop, J.M.3
Blackburn, E.H.4
-
89
-
-
0342561644
-
Cell-cycle-regulated association of RAD50/MRE11/ NBS1 with TRF2 and human telomeres
-
Zhu, X. D., Kuster, B., Mann, M., Petrini, J. H. & de Lange, T. 2000 Cell-cycle-regulated association of RAD50/MRE11/ NBS1 with TRF2 and human telomeres. Nature Genet. 25, 347-352.
-
(2000)
Nature Genet.
, vol.25
, pp. 347-352
-
-
Zhu, X.D.1
Kuster, B.2
Mann, M.3
Petrini, J.H.4
De Lange, T.5
|