Counting of Rif1p and Rif2p on Saccharomyces cerevisiae telomeres regulates telomere length?

Molecular and Cellular Biology

Volumn 24, Issue 24, 2004, Pages 10857-10867

  Levy, Daniel L ^a   Blackburn, Elizabeth H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL DNA; FUNGAL PROTEIN; PDZ PROTEIN; PROTEIN RIF; PROTEIN RIF1P; PROTEIN RIF2P; PROTEIN RIP1P; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA PROTEIN COMPLEX; NONHUMAN; NUCLEOTIDE REPEAT; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SACCHAROMYCES CEREVISIAE; TELOMERE;

BINDING SITES; CARRIER PROTEINS; DNA, FUNGAL; DNA-BINDING PROTEINS; FUNGAL PROTEINS; MODELS, BIOLOGICAL; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TELOMERE; TELOMERE-BINDING PROTEINS; TRANSCRIPTION FACTORS;

MAMMALIA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 10044265469     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.24.24.10857-10867.2004     Document Type: Article

References (51)

1. Alexander, M. K., and V. A. Zakian. 2003. Rap1p telomere association is not required for mitotic stability of a C(3)TA(2) telomere in yeast. EMBO J. 22:1688-1696.
2. Ancelin, K., M. Brunori, S. Bauwens, C.-E. Koering, C. Brun, M. Ricoul, J. P. Pommier, L. Sabatier, and E. Gilson. 2002. Targeting assay to study the cis functions of human telomeric proteins: evidence for inhibition of telomerase by TRF1 and for activation of telomere degradation by TRF2. Mol. Cell. Biol. 22:3474-3487.
3. Blackburn, E. H. 2000. The end of the (DNA) line. Nat. Struct. Biol. 7:847-850.
4. Blackburn, E. H. 2000. Telomere states and cell fates. Nature 408:53-56.
5. Bourns, B. D., M. K. Alexander, A. M. Smith, and V. A. Zakian. 1998. Sir proteins, Rif proteins, and Cdc13p bind Saccharomyces telomeres in vivo. Mol. Cell. Biol. 18:5600-5608.
6. Brachmann, C. B., A. Davies, G. J. Cost, E. Caputo, J. Li, P. Hieter, and J. D. Boeke. 1998. Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications. Yeast 14:115-132.
7. Brevet, V., A. S. Berthiau, L. Civitelli, P. Donini, V. Schramke, V. Geli, F. Ascenzioni, and E. Gilson. 2003. The number of vertebrate repeats can be regulated at yeast telomeres by Rap1-independent mechanisms. EMBO J. 22:1697-1706.
8. Buchman, A. R., W. J. Kimmerly, J. Rine, and R. D. Kornberg. 1988. Two DNA-binding factors recognize specific sequences at silencers, upstream activating sequences, autonomously replicating sequences, and telomeres in Saccharomyces cerevisiae. Mol. Cell. Biol. 8:210-225.
9. Christianson, T. W., R. S. Sikorski, M. Dante, J. H. Shero, and P. Hieter. 1992. Multifunctional yeast high-copy-number shuttle vectors. Gene 110:119-122.
10. Conrad, M. N., J. H. Wright, A. J. Wolf, and V. A. Zakian. 1990. RAP1 protein interacts with yeast telomeres in vivo: overproduction alters telomere structure and decreases chromosome stability. Cell 63:739-750.
11. de Bruin, D., S. M. Kantrow, R. A. Liberatore, and V. A. Zakian. 2000. Telomere folding is required for the stable maintenance of telomere position effects in yeast. Mol. Cell. Biol. 20:7991-8000.
12. Dong, H., P. Zhang, I. Song, R. S. Petralia, D. Liao, and R. L. Huganir. 1999. Characterization of the glutamate receptor-interacting proteins GRIP1 and GRIP2. J. Neurosci. 19:6930-6941.
13. Dueber, J. E., B. J. Yeh, K. Chak, and W. A. Lim. 2003. Reprogramming control of an allosteric signaling switch through modular recombination. Science 301:1904-1908.
14. Enomoto, S., P. D. McCune-Zierath, M. Gerami-Nejad, M. A. Sanders, and J. Berman. 1997. RLF2, a subunit of yeast chromatin assembly factor-I, is required for telomeric chromatin function in vivo. Genes Dev. 11:358-370.
15. Gilson, E., M. Roberge, R. Giraldo, D. Rhodes, and S. M. Gasser. 1993. Distortion of the DNA double helix by RAP1 at silencers and multiple telomeric binding sites. J. Mol. Biol. 231:293-310.
16. Goldstein, A. L., and J. H. McCusker. 1999. Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae. Yeast 15:1541-1553.
17. Gotta, M., T. Laroche, A. Formenton, L. Maillet, H. Scherthan, and S. M. Gasser. 1996. The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisiae. J. Cell Biol. 134:1349-1363.
18. Graham, I. R., R. A. Haw, K. G. Spink, K. A. Halden, and A. Chambers. 1999. In vivo analysis of functional regions within yeast Rap1p. Mol. Cell. Biol. 19:7481-490.
19. Griffith, J. D., L. Comeau, S. Rosenfield, R. M. Stansel, A. Bianchi, H. Moss, and T. de Lange. 1999. Mammalian telomeres end in a large duplex loop. Cell 97:503-514.
20. Grossi, S., A. Bianchi, P. Damay, and D. Shore. 2001. Telomere formation by Rap1p binding site arrays reveals end-specific length regulation requirements and active telomeric recombination. Mol. Cell. Biol. 21:8117-8128.
21. Hardy, C. F., L. Sussel, and D. Shore. 1992. A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation. Genes Dev. 6:801-814.
22. Hediger, F., F. R. Neumann, G. Van Houwe, K. Dubrana, and S. M. Gasser. 2002. Live imaging of telomeres: yKu and Sir proteins define redundant telomere-anchoring pathways in yeast. Curr. Biol. 12:2076-2089.
23. Kanoh, J., and F. Ishikawa. 2001. spRap1 and spRif1, recruited to telomeres by Taz1, are essential for telomere function in fission yeast. Curr. Biol. 11:1624-1630.
24. Krauskopf, A., and E. H. Blackburn. 1996. Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats. Nature 383:354-357.
25. Kyrion, G., K. A. Boakye, and A. J. Lustig. 1992. C-terminal truncation of RAP1 results in the deregulation of telomere size, stability, and function in Saccharomyces cerevisiae. Mol. Cell. Biol. 12:5159-5173.
26. Laroche, T., S. G. Martin, M. Tsai-Pflugfelder, and S. M. Gasser. 2000. The dynamics of yeast telomeres and silencing proteins through the cell cycle. J. Struct. Biol. 129:159-174.
27. Li, B., and A. J. Lustig. 1996. A novel mechanism for telomere size control in Saccharomyces cerevisiae. Genes Dev. 10:1310-1326.
28. Li, B., S. Oestreich, and T. de Lange. 2000. Identification of human Rap1: implications for telomere evolution. Cell 101:471-483.
29. Lieb, J. D., X. Liu, D. Botstein, and P. O. Brown. 2001. Promoter-specific binding of Rap1 revealed by genome-wide maps of protein-DNA association. Nat. Genet. 28:327-334.
30. Longtine, M. S., A. McKenzie III, D. J. Demarini, N. G. Shah, A. Wach, A. Brachat, P. Philippsen, and J. R. Pringle. 1998. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14:953-961.
31. Lydall, D. 2003. Hiding at the ends of yeast chromosomes: telomeres, nucleases and checkpoint pathways. J. Cell Sci. 116:4057-4065.
32. Marcand, S., E. Gilson, and D. Shore. 1997. A protein-counting mechanism for telomere length regulation in yeast. Science 275:986-990.
33. McEachern, M. J., and E. H. Blackburn. 1995. Runaway telomere elongation caused by telomerase RNA gene mutations. Nature 376:403-409.
34. Moretti, P., K. Freeman, L. Coodly, and D. Shore. 1994. Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1. Genes Dev. 8:2257-2269.
35. Muller, T., E. Gilson, R. Schmidt, R. Giraldo, J. Sogo, H. Gross, and S. M. Gasser. 1994. Imaging the asymmetrical DNA bend induced by repressor activator protein 1 with scanning tunneling microscopy. J. Struct. Biol. 113:1-12.
36. Park, S. H., A. Zarrinpar, and W. A. Lim. 2003. Rewiring MAP kinase pathways using alternative scaffold assembly mechanisms. Science 299:1061-1064.
37. Prescott, J. C., and E. H. Blackburn. 2000. Telomerase RNA template mutations reveal sequence-specific requirements for the activation and repression of telomerase action at telomeres. Mol. Cell. Biol. 20:2941-2948.
38. Ray, A., and K. W. Runge. 1999. The yeast telomere length counting machinery is sensitive to sequences at the telomere-nontelomere junction. Mol. Cell. Biol. 19:31-45.
39. Runge, K. W., and V. A. Zakian. 1989. Introduction of extra telomeric DNA sequences into Saccharomyces cerevisiae results in telomere elongation. Mol. Cell. Biol. 9:1488-1497.
40. Rusche, L. N., A. L. Kirchmaier, and J. Rine. 2003. The establishment, inheritance, and function of silenced chromatin in Saccharomyces cerevisiae. Annu. Rev. Biochem. 72:481-516.
41. Sheng, M., and C. Sala. 2001. PDZ domains and the organization of supramolecular complexes. Annu. Rev. Neurosci. 24:1-29.
42. Silverman, J., H. Takai, S. B. C. Buonomo, F. Eisenhaber, and T. de Lange. 2004. Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint. Genes Dev. 18:2108-2119.
43. Smith, C. D., D. L. Smith, J. L. DeRisi, and E. H. Blackburn. 2003. Telomeric protein distributions and remodeling through the cell cycle in Saccharomyces cerevisiae. Mol. Biol. Cell 14:556-570.
44. Smogorzewska, A., B. van Steensel, A. Bianchi, S. Oelmann, M. R. Schaefer, G. Schnapp, and T. de Lange. 2000. Control of human telomere length by TRF1 and TRF2. Mol. Cell. Biol. 20:1659-1668.
45. Strahl-Bolsinger, S., A. Hecht, K. Luo, and M. Grunstein. 1997. SIR2 and SIR4 interactions differ in core and extended telomeric hcterochromatin in yeast. Genes Dev. 11:83-93.
46. Teixeira, M. T., M. Arneric, P. Sperisen, and J. Lingner. 2004. Telomere length homeostasis is achieved via a switch between telomerase-extendible and -nonextendible states. Cell 117:323-335.
47. Teng, S. C., J. Chang, B. McCowan, and V. A. Zakian. 2000. Telomerase-independent lengthening of yeast telomeres occurs by an abrupt Rad50p-dependent, Rif-inhibited recombinational process. Mol. Cell 6:947-952.
48. Vignais, M. L., J. Huet, J. M. Buhler, and A. Sentenac. 1990. Contacts between the factor TUF and RPG sequences. J. Biol. Chem. 265:14669-14674.
49. Vignais, M. L., and A. Sentenac. 1989. Asymmetric DNA bending induced by the yeast multifunctional factor TUF. J. Biol. Chem. 264:8463-8466.
50. Wotton, D., and D. Shore. 1997. A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae. Genes Dev. 11:748-760.
51. Zakian, V. A. 1996. Structure, function, and replication of Saccharomyces cerevisiae telomeres. Annu. Rev. Genet. 30:141-172.