Molecular Biology: RNA polymerase II is required for RNAi-dependent heterochromatin assembly

Science

Volumn 309, Issue 5733, 2005, Pages 467-469

  Kato, Hiroaki ^a   Goto, Derek B ^b   Martienssen, Robert A ^b   Urano, Takeshi ^c   Furukawa, Koichi ^c   Murakami, Yota ^a  

^a KYOTO UNIVERSITY   (Japan)

^b Simons Center for Quantitative Biology   (United States)

^c NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

POLYMERS; RNA; SURFACE TREATMENT;

PERICENTROMERIC TRANSCRIPTION; RNA INTERFERENCE (RNAI); RNA POLYMERASE II (RNAPII); SMALL INTERFERING RNAS (SIRNA);

MOLECULAR BIOLOGY;

HISTONE; RNA POLYMERASE II; SMALL INTERFERING RNA; FUNGAL RNA; MESSENGER RNA;

RNA;

ARTICLE; CENTROMERE; ENZYME LOCALIZATION; ENZYME SUBUNIT; HETEROCHROMATIN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN MODIFICATION; RNA INTERFERENCE; RNA TRANSCRIPTION; SCHIZOSACCHAROMYCES POMBE; WILD TYPE; AMINO ACID SEQUENCE; CHEMISTRY; CHROMOSOME SEGREGATION; DNA MICROARRAY; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; METHYLATION; MOLECULAR GENETICS; POINT MUTATION; SCHIZOSACCHAROMYCES;

SCHIZOSACCHAROMYCES POMBE;

AMINO ACID SEQUENCE; CENTROMERE; CHROMOSOME SEGREGATION; GENE EXPRESSION REGULATION, FUNGAL; HETEROCHROMATIN; HISTONES; METHYLATION; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POINT MUTATION; RNA INTERFERENCE; RNA POLYMERASE II; RNA, FUNGAL; RNA, MESSENGER; RNA, SMALL INTERFERING; SCHIZOSACCHAROMYCES; TRANSCRIPTION, GENETIC;

EID: 22344434734     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1114955     Document Type: Article

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21. We thank R. C. Allshire, S. I. S. Grewal, D. Q. Ding, and Y. Hiraoka for their gifts of strains and plasmids, and members of the Murakami laboratory and K. Tanaka for their support and discussions. D.B.G. is a U.S. Department of Energy-Energy Biosciences Research Fellow of the Life Sciences Research Foundation. This work is supported in part by a grant from NIH (R01-GM067014) to R.A.M., and by a Grant-in-aid for Scientific Research (B) to Y.M. from the Japan Society for the Promotion of Science.